ATE243882T1 - Keimbildung und wachstum von metalloxid- nanopartikeln und verwendung - Google Patents

Keimbildung und wachstum von metalloxid- nanopartikeln und verwendung

Info

Publication number
ATE243882T1
ATE243882T1 AT99925247T AT99925247T ATE243882T1 AT E243882 T1 ATE243882 T1 AT E243882T1 AT 99925247 T AT99925247 T AT 99925247T AT 99925247 T AT99925247 T AT 99925247T AT E243882 T1 ATE243882 T1 AT E243882T1
Authority
AT
Austria
Prior art keywords
magnetic
metal
oxide
metal ions
solution
Prior art date
Application number
AT99925247T
Other languages
English (en)
Inventor
Shlomo Margel
Sigalit Gura
Original Assignee
Univ Bar Ilan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bar Ilan filed Critical Univ Bar Ilan
Application granted granted Critical
Publication of ATE243882T1 publication Critical patent/ATE243882T1/de

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1878Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles the nanoparticle having a magnetically inert core and a (super)(para)magnetic coating
    • A61K49/1881Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles the nanoparticle having a magnetically inert core and a (super)(para)magnetic coating wherein the coating consists of chelates, i.e. chelating group complexing a (super)(para)magnetic ion, bound to the surface
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • G01N33/5434Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01FMAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0054Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01FMAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/44Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids
    • H01F1/445Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids the magnetic component being a compound, e.g. Fe3O4
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/20Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/30Magnetic particle immunoreagent carriers the magnetic material being dispersed in the polymer composition before their conversion into particulate form
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers
    • G01N2446/80Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/84Polymer coating, e.g. gelatin

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Power Engineering (AREA)
  • Hematology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Hard Magnetic Materials (AREA)
  • Compounds Of Iron (AREA)
  • Soft Magnetic Materials (AREA)
  • Medicinal Preparation (AREA)
AT99925247T 1998-05-26 1999-05-24 Keimbildung und wachstum von metalloxid- nanopartikeln und verwendung ATE243882T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8472698A 1998-05-26 1998-05-26
PCT/IL1999/000275 WO1999062079A1 (en) 1998-05-26 1999-05-24 Nucleation and growth of magnetic metal oxide nanoparticles and its use

Publications (1)

Publication Number Publication Date
ATE243882T1 true ATE243882T1 (de) 2003-07-15

Family

ID=22186847

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99925247T ATE243882T1 (de) 1998-05-26 1999-05-24 Keimbildung und wachstum von metalloxid- nanopartikeln und verwendung

Country Status (7)

Country Link
EP (1) EP1088315B1 (de)
JP (1) JP2002517085A (de)
AT (1) ATE243882T1 (de)
AU (1) AU4161399A (de)
DE (1) DE69909090T2 (de)
IL (1) IL139638A0 (de)
WO (1) WO1999062079A1 (de)

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US20110014296A1 (en) * 2009-07-17 2011-01-20 National Chiao Tung University Drug Delivery Nanodevice, its Preparation Method and Uses Thereof
WO2013094711A1 (ja) 2011-12-21 2013-06-27 Jnc株式会社 磁性粒子を用いた水溶液中のセシウムイオンの除去方法
JP5920820B2 (ja) * 2012-03-05 2016-05-18 国立研究開発法人産業技術総合研究所 磁性ナノ粒子固定型酸化オスミウム
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KR20170097510A (ko) 2016-02-18 2017-08-28 연세대학교 산학협력단 T1 mri 조영제로서의 나노입자의 분산 안정도를 증가시키는 방법 및 t1 mri 조영제 나노입자
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KR102075593B1 (ko) * 2018-01-02 2020-02-10 경희대학교 산학협력단 균일한 크기의 자성 아밀로오스 마이크로비드의 제조 방법 및 이의 응용
CN117064634A (zh) 2018-03-01 2023-11-17 巴伊兰大学 用于修正眼部状态的系统、方法及材料组成物
CN108636366A (zh) * 2018-04-17 2018-10-12 江苏国创环保科技有限公司 一种吸附重金属的磁性吸附材料的制备方法及应用
US12281021B2 (en) 2018-06-01 2025-04-22 The Regents Of The University Of California System and method for making boron oxide nanoparticles
CN113289587B (zh) * 2021-05-10 2023-11-28 苏州君盟生物医药科技有限公司 巯基修饰的磁性纳米微球及其制备方法、应用
CN113881661A (zh) * 2021-09-29 2022-01-04 淮阴工学院 基于羧甲基淀粉修饰的磁性纳米粒子固定化酶的方法
KR102928416B1 (ko) 2021-11-15 2026-02-19 가톨릭대학교 산학협력단 입자 크기를 조절할 수 있는 하프늄 나노입자 제조방법
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CN116037135B (zh) * 2023-02-15 2024-08-27 中国科学技术大学 一种人工纳米蛋白酶在蛋白质水解中的应用
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Also Published As

Publication number Publication date
DE69909090T2 (de) 2004-05-19
WO1999062079A1 (en) 1999-12-02
EP1088315B1 (de) 2003-06-25
AU4161399A (en) 1999-12-13
IL139638A0 (en) 2002-02-10
JP2002517085A (ja) 2002-06-11
EP1088315A1 (de) 2001-04-04
DE69909090D1 (de) 2003-07-31

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