ATE243882T1 - Keimbildung und wachstum von metalloxid- nanopartikeln und verwendung - Google Patents

Keimbildung und wachstum von metalloxid- nanopartikeln und verwendung

Info

Publication number
ATE243882T1
ATE243882T1 AT99925247T AT99925247T ATE243882T1 AT E243882 T1 ATE243882 T1 AT E243882T1 AT 99925247 T AT99925247 T AT 99925247T AT 99925247 T AT99925247 T AT 99925247T AT E243882 T1 ATE243882 T1 AT E243882T1
Authority
AT
Austria
Prior art keywords
magnetic
metal
oxide
metal ions
solution
Prior art date
Application number
AT99925247T
Other languages
English (en)
Inventor
Shlomo Margel
Sigalit Gura
Original Assignee
Univ Bar Ilan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bar Ilan filed Critical Univ Bar Ilan
Application granted granted Critical
Publication of ATE243882T1 publication Critical patent/ATE243882T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
    • A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
    • A61K49/1821—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles
    • A61K49/1824—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles
    • A61K49/1878—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles the nanoparticle having a magnetically inert core and a (super)(para)magnetic coating
    • A61K49/1881—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles the nanoparticle having a magnetically inert core and a (super)(para)magnetic coating wherein the coating consists of chelates, i.e. chelating group complexing a (super)(para)magnetic ion, bound to the surface
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0054—Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/44—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids
    • H01F1/445—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids the magnetic component being a compound, e.g. Fe3O4
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/30—Magnetic particle immunoreagent carriers the magnetic material being dispersed in the polymer composition before their conversion into particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/84—Polymer coating, e.g. gelatin

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Power Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Compounds Of Iron (AREA)
  • Hard Magnetic Materials (AREA)
  • Medicinal Preparation (AREA)
  • Soft Magnetic Materials (AREA)
AT99925247T 1998-05-26 1999-05-24 Keimbildung und wachstum von metalloxid- nanopartikeln und verwendung ATE243882T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8472698A 1998-03-09 1998-03-09
PCT/IL1999/000275 WO1999062079A1 (en) 1998-05-26 1999-05-24 Nucleation and growth of magnetic metal oxide nanoparticles and its use

Publications (1)

Publication Number Publication Date
ATE243882T1 true ATE243882T1 (de) 2003-07-15

Family

ID=22186847

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99925247T ATE243882T1 (de) 1998-05-26 1999-05-24 Keimbildung und wachstum von metalloxid- nanopartikeln und verwendung

Country Status (7)

Country Link
EP (1) EP1088315B1 (de)
JP (1) JP2002517085A (de)
AT (1) ATE243882T1 (de)
AU (1) AU4161399A (de)
DE (1) DE69909090T2 (de)
IL (1) IL139638A0 (de)
WO (1) WO1999062079A1 (de)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7393698B2 (en) * 2000-08-21 2008-07-01 National Institute Of Advanced Industrial Science And Technology Magnetic fine particles and process for producing the same
US7589070B2 (en) 2001-06-15 2009-09-15 The Children's Hospital Of Philadelphia Surface modification for improving biocompatibility
WO2003015109A1 (en) * 2001-08-09 2003-02-20 The Circle For The Promotion Of Science And Engineering Composite magnetic material prepared by compression forming of ferrite-coated metal particles and method for preparation thereof
US7462366B2 (en) * 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
FR2841156B1 (fr) * 2002-06-19 2004-09-10 Bio Merieux Nouvelles particules magnetiques fluorescentes,ainsi que les conjugues de telles particules et les compositions diagnostiques , therapeutiques ou prophylactiques les contenant
WO2004045494A2 (en) 2002-11-20 2004-06-03 Bar-Ilan University Biological glue based on thrombin-conjugated nanoparticles
FR2855315B1 (fr) * 2003-05-23 2005-08-19 Centre Nat Rech Scient Ferrofluides stables en milieu neutre et ferrofluides modifies obtenus par modification de la surface des particules de ces ferrofluides
JP2007505311A (ja) * 2003-09-09 2007-03-08 コニンクリユケ フィリップス エレクトロニクス エヌ．ブイ． 検体を検出するためのナノ粒子
JP4705377B2 (ja) * 2004-03-03 2011-06-22 ソニー株式会社 配線基板
US20060105052A1 (en) * 2004-11-15 2006-05-18 Acar Havva Y Cationic nanoparticle having an inorganic core
WO2006085668A1 (en) * 2005-02-08 2006-08-17 Fujifilm Corporation Magnetic composite body, production method thereof, method for removing substance with mannose on its surface, and method for concentrating substance with mannose on its surface
JP4903449B2 (ja) * 2005-02-08 2012-03-28 富士フイルム株式会社 磁性複合体およびその製造方法、マンノースを表面に有する物質の除去方法及びマンノースを表面に有する物質の濃縮方法
US8084275B2 (en) * 2005-02-08 2011-12-27 Fujifilm Corporation Magnetic composite body, production method thereof, method for removing substance with mannose on its surface, and method for concentrating substance with mannose on its surface
JP5174654B2 (ja) * 2005-03-21 2013-04-03 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 官能基化された磁性ナノ粒子およびその使用法
JP2006347949A (ja) * 2005-06-15 2006-12-28 Toda Kogyo Corp 磁性粒子含有医薬用原薬
DE102005047691A1 (de) * 2005-09-23 2007-03-29 Siemens Ag Mehrfach umhülltes Nanopartikel für die Krebstherapie
US20070140974A1 (en) * 2005-12-15 2007-06-21 General Electric Company Targeted nanoparticles for magnetic resonance imaging
EP1968649A4 (de) * 2005-12-20 2012-12-19 Fujifilm Corp Protein-nanoteilchen und ihre verwendung
JP2007335446A (ja) * 2006-06-12 2007-12-27 Sony Corp 配線基板
KR100846839B1 (ko) * 2006-12-05 2008-07-16 재단법인서울대학교산학협력재단 산화금속 중공 나노캡슐 및 이의 제조방법
DE102007004424A1 (de) * 2007-01-23 2008-07-24 Bayer Schering Pharma Aktiengesellschaft Eisenoxid-bindende Peptide
EP1970705A1 (de) * 2007-03-15 2008-09-17 Koninklijke Philips Electronics N.V. Analytnachweis anhand von Kügelchen
JP5176411B2 (ja) 2007-06-29 2013-04-03 Ｊｎｃ株式会社 上限臨界溶液温度を有する高分子の水溶液、この高分子で修飾された粒子の水分散体、及びそれらの保存方法
US8105493B2 (en) 2007-06-29 2012-01-31 Jnc Corporation Aggregation and dispersion methods of magnetic particles, separation and detection methods using the same and detection kit
WO2009040811A2 (en) * 2007-09-24 2009-04-02 Bar-Ilan University Polymer nanoparticles coated by magnetic metal oxide and uses thereof
JP2010208875A (ja) * 2009-03-09 2010-09-24 Tokyo Institute Of Technology 磁性中空粒子およびその製造方法
US20110014296A1 (en) * 2009-07-17 2011-01-20 National Chiao Tung University Drug Delivery Nanodevice, its Preparation Method and Uses Thereof
EP2797081A4 (de) * 2011-12-21 2016-04-06 Jnc Corp Verfahren zum entfernen von cäsiumionen in wässrigen lösungen unter verwendung magnetischer partikel
JP5920820B2 (ja) * 2012-03-05 2016-05-18 国立研究開発法人産業技術総合研究所 磁性ナノ粒子固定型酸化オスミウム
ES2439167B1 (es) * 2012-06-21 2014-11-17 Consejo Superior De Investigaciones Científicas (Csic) Compuestos con funcionalidad magnética, implantes o geles derivados de ellos, y el uso de ambos para determinar la actividad enzimática de una enzima
PL227182B1 (pl) * 2012-11-21 2017-11-30 Univ Jagiellonski Superparamagnetyczne nanoczastki tlenku zelaza z ultracienkimi warstwami polimerowymi, sposób ich wytwarzania i zastosowanie
KR101991912B1 (ko) * 2013-01-04 2019-06-24 주식회사 인벤테라제약 나노입자 지지체 표면에 코팅된 t1 조영물질을 포함하는 mri 조영제
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KR20170097510A (ko) * 2016-02-18 2017-08-28 연세대학교 산학협력단 T1 mri 조영제로서의 나노입자의 분산 안정도를 증가시키는 방법 및 t1 mri 조영제 나노입자
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KR102075593B1 (ko) * 2018-01-02 2020-02-10 경희대학교 산학협력단 균일한 크기의 자성 아밀로오스 마이크로비드의 제조 방법 및 이의 응용
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CN108636366A (zh) * 2018-04-17 2018-10-12 江苏国创环保科技有限公司 一种吸附重金属的磁性吸附材料的制备方法及应用
WO2019232312A1 (en) * 2018-06-01 2019-12-05 The Regents Of The University Of California System and method for making boron oxide nanoparticles
CN113289587B (zh) * 2021-05-10 2023-11-28 苏州君盟生物医药科技有限公司 巯基修饰的磁性纳米微球及其制备方法、应用
CN113881661A (zh) * 2021-09-29 2022-01-04 淮阴工学院 基于羧甲基淀粉修饰的磁性纳米粒子固定化酶的方法
CN114990101B (zh) * 2022-06-17 2024-01-12 上海中器环保科技有限公司 一种磁性纳米颗粒复合载体固定化脂肪酶及其制备方法
CN116037135B (zh) * 2023-02-15 2024-08-27 中国科学技术大学 一种人工纳米蛋白酶在蛋白质水解中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3582649D1 (de) * 1984-11-01 1991-05-29 Technicon Instr Magnetisch empfindlicher reagenstraeger und verfahren zur herstellung.
US5062991A (en) * 1990-06-04 1991-11-05 Coulter Corporation In situ use of gelatin in the preparation of uniform ferrite particles
US5349957A (en) * 1992-12-02 1994-09-27 Sterling Winthrop Inc. Preparation and magnetic properties of very small magnetite-dextran particles

Also Published As

Publication number Publication date
IL139638A0 (en) 2002-02-10
DE69909090D1 (de) 2003-07-31
WO1999062079A1 (en) 1999-12-02
EP1088315A1 (de) 2001-04-04
AU4161399A (en) 1999-12-13
DE69909090T2 (de) 2004-05-19
EP1088315B1 (de) 2003-06-25
JP2002517085A (ja) 2002-06-11

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