ATE24320T1 - Azabicyclo-alkyl-derivate. - Google Patents

Azabicyclo-alkyl-derivate.

Info

Publication number
ATE24320T1
ATE24320T1 AT82109116T AT82109116T ATE24320T1 AT E24320 T1 ATE24320 T1 AT E24320T1 AT 82109116 T AT82109116 T AT 82109116T AT 82109116 T AT82109116 T AT 82109116T AT E24320 T1 ATE24320 T1 AT E24320T1
Authority
AT
Austria
Prior art keywords
azabicyclo
alkyl derivatives
derivatives
alkyl
Prior art date
Application number
AT82109116T
Other languages
English (en)
Inventor
Michael Stewart Hadley
Francis David King
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Application granted granted Critical
Publication of ATE24320T1 publication Critical patent/ATE24320T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT82109116T 1978-12-30 1979-12-20 Azabicyclo-alkyl-derivate. ATE24320T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB7850380 1978-12-30
GB7909262 1979-03-15
GB7927831 1979-08-09
EP79302978A EP0013138B1 (de) 1978-12-30 1979-12-20 Azabicycloalkyl-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE24320T1 true ATE24320T1 (de) 1987-01-15

Family

ID=27260652

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82109116T ATE24320T1 (de) 1978-12-30 1979-12-20 Azabicyclo-alkyl-derivate.

Country Status (14)

Country Link
US (5) US4273778A (de)
EP (3) EP0081054B1 (de)
AR (1) AR225301A1 (de)
AT (1) ATE24320T1 (de)
AU (2) AU527837B2 (de)
CA (2) CA1218062A (de)
DE (3) DE2966476D1 (de)
DK (1) DK553979A (de)
ES (1) ES487379A0 (de)
IE (2) IE49736B1 (de)
IL (1) IL59004A0 (de)
MX (1) MX6255E (de)
NZ (1) NZ192476A (de)
ZA (1) ZA797054B (de)

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EP0069481A1 (de) * 1981-06-17 1983-01-12 Beecham Group Plc Azabicycloalkylbenzamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
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ZA832549B (en) * 1982-04-14 1988-09-28 Beecham Group Plc Pharmaceutically active compounds
CA1223873A (en) * 1982-04-14 1987-07-07 Francis D. King Pharmaceutically active compounds
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AU1508183A (en) * 1982-06-04 1983-12-08 Beecham Group Plc Benzamide and anilide derivatives of 8-azabicyclo-(3.2.1)- -octane
FI74707C (fi) * 1982-06-29 1988-03-10 Sandoz Ag Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror.
EP0099194A3 (de) * 1982-07-03 1984-04-11 Beecham Group Plc Benzamide
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EP0101641A3 (de) * 1982-07-22 1984-03-28 Beecham Group Plc Sulphonylamino-aza-bicycloalkyl-Derivate
EP0102195A3 (de) * 1982-08-03 1984-04-11 Beecham Group Plc Substituierte Azabicycloalkyl-Derivate mit dopaminantagonistischer Wirkung
WO1984001151A1 (en) * 1982-09-24 1984-03-29 Beecham Group Plc Amino-azabicycloalkyl derivatives as dopamine antagonists
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GB8516371D0 (en) * 1985-06-28 1985-07-31 Beecham Group Plc Compounds
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AT396870B (de) * 1986-08-07 1993-12-27 Sandoz Ag Verfahren zur herstellung einer galenischen formulierung zur nasalen verabreichung von serotoninantagonisten
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Also Published As

Publication number Publication date
EP0220339B1 (de) 1989-11-08
US4336259A (en) 1982-06-22
DE2967692D1 (de) 1989-12-14
DK553979A (da) 1980-08-15
AU9135182A (en) 1983-03-10
AU543825B2 (en) 1985-05-02
AU527837B2 (en) 1983-03-24
ZA797054B (en) 1980-12-31
IE49737B1 (en) 1985-12-11
EP0220339A1 (de) 1987-05-06
EP0013138B1 (de) 1983-12-07
NZ192476A (en) 1982-09-14
EP0081054B1 (de) 1986-12-17
US4705858A (en) 1987-11-10
DE2967642D1 (de) 1987-01-29
US4273778A (en) 1981-06-16
DE2966476D1 (en) 1984-01-12
CA1220473A (en) 1987-04-14
AU5425579A (en) 1980-07-03
ES8101072A1 (es) 1980-12-01
EP0081054A3 (en) 1983-08-24
IL59004A0 (en) 1980-03-31
AR225301A1 (es) 1982-03-15
MX6255E (es) 1985-02-15
IE792524L (en) 1980-06-30
ES487379A0 (es) 1980-12-01
US4599420A (en) 1986-07-08
EP0013138A1 (de) 1980-07-09
US4544660A (en) 1985-10-01
CA1218062A (en) 1987-02-17
IE49736B1 (en) 1985-12-11
EP0081054A2 (de) 1983-06-15

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