IT1255467B - Ammidi acriliche farmacologicamente attive - Google Patents
Ammidi acriliche farmacologicamente attiveInfo
- Publication number
- IT1255467B IT1255467B ITMI921851A ITMI921851A IT1255467B IT 1255467 B IT1255467 B IT 1255467B IT MI921851 A ITMI921851 A IT MI921851A IT MI921851 A ITMI921851 A IT MI921851A IT 1255467 B IT1255467 B IT 1255467B
- Authority
- IT
- Italy
- Prior art keywords
- starches
- pharmacologically active
- formula
- active acrylic
- acrylic
- Prior art date
Links
- 229920002472 Starch Polymers 0.000 title 1
- 235000019698 starch Nutrition 0.000 title 1
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical class NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000000954 anitussive effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000002825 nitriles Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Vengono descritte ammidi acriliche di formula (FORMULA I) in cui Ar rappresenta un radicale piridile o benzile eventualmente sostituito; Ra rappresenta idrogeno, alchile inferiore, fenile, nitrile; Q rappresenta il radicale tropile o chinuclidile eventualmente N-ossido.I composti di formula (I) presentano attività antitosse.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI921851A IT1255467B (it) | 1992-07-29 | 1992-07-29 | Ammidi acriliche farmacologicamente attive |
| EP19930111579 EP0581165A3 (en) | 1992-07-29 | 1993-07-20 | Acrylamide derivatives as antirussive agent |
| JP5188048A JPH0710872A (ja) | 1992-07-29 | 1993-07-29 | アミド誘導体およびそれを含有する鎮咳活性を有する調剤学的組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI921851A IT1255467B (it) | 1992-07-29 | 1992-07-29 | Ammidi acriliche farmacologicamente attive |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI921851A0 ITMI921851A0 (it) | 1992-07-29 |
| ITMI921851A1 ITMI921851A1 (it) | 1994-01-29 |
| IT1255467B true IT1255467B (it) | 1995-11-02 |
Family
ID=11363773
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI921851A IT1255467B (it) | 1992-07-29 | 1992-07-29 | Ammidi acriliche farmacologicamente attive |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0581165A3 (it) |
| JP (1) | JPH0710872A (it) |
| IT (1) | IT1255467B (it) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1265057B1 (it) * | 1993-08-05 | 1996-10-28 | Dompe Spa | Tropil 7-azaindolil-3-carbossiamidi |
| SE9903760D0 (sv) | 1999-10-18 | 1999-10-18 | Astra Ab | New compounds |
| SE9904176D0 (sv) | 1999-11-18 | 1999-11-18 | Astra Ab | New use |
| AU2002339810A1 (en) * | 2001-10-16 | 2003-04-28 | Astrazeneca Ab | Azabicyclic compounds for the treatment of fibromyalgia syndrome |
| KR101563370B1 (ko) * | 2007-01-08 | 2015-10-26 | 앤드로사이언스 코포레이션 | (치환된 페닐)-프로페날 잔기를 갖는 화합물, 이의 유도체, 생물학적 활성, 및 이의 용도 |
| AR085073A1 (es) * | 2012-01-11 | 2013-09-11 | Richmond Sa Com Ind Y Financiera Lab | Compuestos con actividad antibacteriana, un procedimiento para su obtencion y composiciones farmaceuticas que los comprenden |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL59004A0 (en) * | 1978-12-30 | 1980-03-31 | Beecham Group Ltd | Substituted benzamides their preparation and pharmaceutical compositions containing them |
| DE4115215A1 (de) * | 1991-05-10 | 1992-11-12 | Merck Patent Gmbh | Indolderivate |
-
1992
- 1992-07-29 IT ITMI921851A patent/IT1255467B/it active IP Right Grant
-
1993
- 1993-07-20 EP EP19930111579 patent/EP0581165A3/en not_active Withdrawn
- 1993-07-29 JP JP5188048A patent/JPH0710872A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ITMI921851A0 (it) | 1992-07-29 |
| ITMI921851A1 (it) | 1994-01-29 |
| JPH0710872A (ja) | 1995-01-13 |
| EP0581165A2 (en) | 1994-02-02 |
| EP0581165A3 (en) | 1994-06-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |