NL7900354A - Spirothienohydantoinen. - Google Patents
Spirothienohydantoinen.Info
- Publication number
- NL7900354A NL7900354A NL7900354A NL7900354A NL7900354A NL 7900354 A NL7900354 A NL 7900354A NL 7900354 A NL7900354 A NL 7900354A NL 7900354 A NL7900354 A NL 7900354A NL 7900354 A NL7900354 A NL 7900354A
- Authority
- NL
- Netherlands
- Prior art keywords
- spirothienohydanoins
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/870,542 US4127665A (en) | 1978-01-18 | 1978-01-18 | Thienohydantoin derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NL7900354A true NL7900354A (nl) | 1979-07-20 |
| NL176459B NL176459B (nl) | 1984-11-16 |
Family
ID=25355609
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE7900354,A NL176459B (nl) | 1978-01-18 | 1979-01-17 | Farmaceutisch preparaat met remmende werking op aldose-reductase, alsmede tricyclisch, gecondenseerd heterocyclisch imide. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4127665A (nl) |
| JP (1) | JPS54109975A (nl) |
| BE (1) | BE873500A (nl) |
| DE (1) | DE2901477C2 (nl) |
| DK (1) | DK151260C (nl) |
| FR (1) | FR2415112A1 (nl) |
| GB (1) | GB2012759B (nl) |
| IE (1) | IE47726B1 (nl) |
| IT (1) | IT1110007B (nl) |
| LU (1) | LU80795A1 (nl) |
| NL (1) | NL176459B (nl) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4147797A (en) * | 1978-08-11 | 1979-04-03 | Pfizer Inc. | Spiro-furanohydantoin derivatives |
| US4181728A (en) * | 1978-11-16 | 1980-01-01 | Pfizer Inc. | Spiro-polycyclicimidazolidinedione derivatives |
| US4181729A (en) * | 1979-03-21 | 1980-01-01 | Pfizer Inc. | Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives |
| US4210667A (en) * | 1979-04-19 | 1980-07-01 | Pfizer Inc. | Pharmaceutical preparations containing coumarin carboxylic acid derivatives |
| AU532110B2 (en) * | 1979-11-13 | 1983-09-15 | Ici Ltd. | Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives |
| EP0065393B1 (en) * | 1981-05-12 | 1984-12-27 | Imperial Chemical Industries Plc | Pyrrole derivatives |
| US4540700A (en) * | 1982-04-15 | 1985-09-10 | Alcon Laboratories, Inc. | Treatment of diabetic complications with certain spiro-imidazolidine-diones |
| US4464385A (en) * | 1982-04-15 | 1984-08-07 | Alcon Laboratories, Inc. | Treatment of diabetic complications with hydantoins |
| US4438272A (en) | 1982-04-15 | 1984-03-20 | Alcon Laboratories, Inc. | Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones |
| US4436745A (en) | 1982-04-15 | 1984-03-13 | Alcon Laboratories, Inc. | Method of inhibiting aldose reductase activity |
| US5070100A (en) * | 1983-09-14 | 1991-12-03 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives |
| US4537892A (en) * | 1983-09-14 | 1985-08-27 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase |
| US4864028A (en) * | 1983-09-14 | 1989-09-05 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives |
| US5153211A (en) * | 1983-09-14 | 1992-10-06 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase |
| HU198212B (en) * | 1984-07-20 | 1989-08-28 | Pfizer | Process for production of spiro-imidasolones |
| US4966911A (en) * | 1984-11-20 | 1990-10-30 | Washington Research Foundation | Immunoregulatory agents |
| US5340829A (en) * | 1984-11-20 | 1994-08-23 | Washington Research Foundation | Immunoregulatory agents |
| JP2708507B2 (ja) * | 1988-04-07 | 1998-02-04 | 株式会社三和化学研究所 | （ｄ）‐６‐フルオロ‐２，３‐ジヒドロ‐２’，５’‐ジオキソ‐スピロ［４Ｈ‐１‐ベンゾピラン‐４，４’‐イミダゾリジン］‐２‐カルボキサミド誘導体、これらの製法及び用途 |
| WO1992000071A1 (en) * | 1989-02-10 | 1992-01-09 | Washington Research Foundation | Immunoregulatory agents |
| BR122021013836B1 (pt) * | 2009-12-04 | 2022-05-24 | Sunovion Pharmaceuticals, Inc. | Composto e seu uso, composição farmacêutica |
| JP2019523279A (ja) | 2016-07-29 | 2019-08-22 | サノビオン ファーマシューティカルズ インクＳｕｎｏｖｉｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． | 化合物および組成物ならびにそれらの使用 |
| MX2019000980A (es) | 2016-07-29 | 2019-07-04 | Sunovion Pharmaceuticals Inc | Compuestos y composiciones y usos de los mismos. |
| JP7146782B2 (ja) | 2017-02-16 | 2022-10-04 | サノビオン ファーマシューティカルズ インク | 統合失調症を処置する方法 |
| MX2020000523A (es) | 2017-08-02 | 2020-08-20 | Sunovion Pharmaceuticals Inc | Compuestos de isocromano y usos de los mismos. |
| CN118406063A (zh) | 2018-02-16 | 2024-07-30 | 赛诺维信制药公司 | 盐、晶型及其制备方法 |
| US11136304B2 (en) | 2019-03-14 | 2021-10-05 | Sunovion Pharmaceuticals Inc. | Salts of a heterocyclic compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
| MX2022012833A (es) | 2020-04-14 | 2022-11-07 | Sunovion Pharmaceuticals Inc | (s)-(4,5-dihidro-7h-tieno[2,3-c]piran-7-il)-n-metilmetanamina para tratar trastornos neurologicos y psiquiatricos. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB796069A (en) * | 1955-12-23 | 1958-06-04 | Ici Ltd | Substituted hydantoins |
| DE1135915B (de) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Verfahren zur Herstellung neuer, antikonvulsiv wirksamer Spirohydantoine |
| CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
-
1978
- 1978-01-18 US US05/870,542 patent/US4127665A/en not_active Expired - Lifetime
-
1979
- 1979-01-16 DE DE2901477A patent/DE2901477C2/de not_active Expired
- 1979-01-16 BE BE0/192915A patent/BE873500A/xx not_active IP Right Cessation
- 1979-01-16 LU LU80795A patent/LU80795A1/xx unknown
- 1979-01-17 IT IT19369/79A patent/IT1110007B/it active
- 1979-01-17 DK DK019579A patent/DK151260C/da not_active IP Right Cessation
- 1979-01-17 NL NLAANVRAGE7900354,A patent/NL176459B/nl not_active IP Right Cessation
- 1979-01-17 FR FR7901155A patent/FR2415112A1/fr active Granted
- 1979-01-17 GB GB791692A patent/GB2012759B/en not_active Expired
- 1979-01-17 JP JP444379A patent/JPS54109975A/ja active Granted
- 1979-01-30 IE IE88/79A patent/IE47726B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2901477A1 (de) | 1979-07-19 |
| JPS54109975A (en) | 1979-08-29 |
| IE47726B1 (en) | 1984-05-30 |
| FR2415112B1 (nl) | 1983-01-14 |
| IE790088L (en) | 1979-07-18 |
| BE873500A (fr) | 1979-07-16 |
| DK151260C (da) | 1988-05-09 |
| NL176459B (nl) | 1984-11-16 |
| GB2012759A (en) | 1979-08-01 |
| IT1110007B (it) | 1985-12-23 |
| GB2012759B (en) | 1982-05-26 |
| DK19579A (da) | 1979-07-19 |
| LU80795A1 (fr) | 1979-09-07 |
| US4127665A (en) | 1978-11-28 |
| DK151260B (da) | 1987-11-16 |
| DE2901477C2 (de) | 1982-06-09 |
| JPS612067B2 (nl) | 1986-01-22 |
| IT7919369A0 (it) | 1979-01-17 |
| FR2415112A1 (fr) | 1979-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1A | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| A85 | Still pending on 85-01-01 | ||
| V1 | Lapsed because of non-payment of the annual fee |