FI841359A0 - Fenyl-kinolizidiner. - Google Patents

Fenyl-kinolizidiner.

Info

Publication number
FI841359A0
FI841359A0 FI841359A FI841359A FI841359A0 FI 841359 A0 FI841359 A0 FI 841359A0 FI 841359 A FI841359 A FI 841359A FI 841359 A FI841359 A FI 841359A FI 841359 A0 FI841359 A0 FI 841359A0
Authority
FI
Finland
Prior art keywords
kinolizidiner
phenyl
Prior art date
Application number
FI841359A
Other languages
English (en)
Other versions
FI70017C (fi
FI70017B (fi
FI841359A (fi
Inventor
Rene Imhof
Emilio Kyburz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI841359A0 publication Critical patent/FI841359A0/fi
Publication of FI841359A publication Critical patent/FI841359A/fi
Application granted granted Critical
Publication of FI70017B publication Critical patent/FI70017B/fi
Publication of FI70017C publication Critical patent/FI70017C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI841359A 1978-10-13 1984-04-05 Foerfarande foer framstaellning av nya farmakologiskt aktiva fenylkinolizidiner FI70017C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH1065478 1978-10-13
CH1065478 1978-10-13
CH715679 1979-08-03
CH715679 1979-08-03
FI793182 1979-10-12
FI793182A FI66611C (fi) 1978-10-13 1979-10-12 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenyl-kinolizidiner

Publications (4)

Publication Number Publication Date
FI841359A0 true FI841359A0 (fi) 1984-04-05
FI841359A FI841359A (fi) 1984-04-05
FI70017B FI70017B (fi) 1986-01-31
FI70017C FI70017C (fi) 1986-09-12

Family

ID=25700857

Family Applications (2)

Application Number Title Priority Date Filing Date
FI793182A FI66611C (fi) 1978-10-13 1979-10-12 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenyl-kinolizidiner
FI841359A FI70017C (fi) 1978-10-13 1984-04-05 Foerfarande foer framstaellning av nya farmakologiskt aktiva fenylkinolizidiner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI793182A FI66611C (fi) 1978-10-13 1979-10-12 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenyl-kinolizidiner

Country Status (22)

Country Link
US (6) US4236010A (fi)
EP (2) EP0044573B1 (fi)
AR (3) AR230446A1 (fi)
AT (1) ATE877T1 (fi)
AU (1) AU533075B2 (fi)
BR (1) BR7906543A (fi)
CA (1) CA1140927A (fi)
CS (2) CS613879A2 (fi)
CU (1) CU35149A (fi)
DE (2) DE2966740D1 (fi)
DK (1) DK433779A (fi)
ES (7) ES8200680A1 (fi)
FI (2) FI66611C (fi)
GR (1) GR73144B (fi)
HU (1) HU180249B (fi)
IE (1) IE49082B1 (fi)
IL (1) IL58415A (fi)
MC (1) MC1289A1 (fi)
NO (1) NO152787C (fi)
NZ (1) NZ191763A (fi)
PH (1) PH16131A (fi)
PT (1) PT70309A (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ191763A (en) * 1978-10-13 1984-05-31 Hoffmann La Roche 7-beta-phenyl-quinolidines, intermediates and pharmaceutical compositions
DK116181A (da) * 1980-04-11 1981-10-12 Hoffmann La Roche Fremgangsmaade til fremstilling af quinolizidinderivater
US4889848A (en) * 1984-11-06 1989-12-26 Hoffmann-La Roche Inc. Tricyclic pyridine derivatives
ZW17385A1 (en) * 1984-11-06 1986-02-19 Hoffmann La Roche Tricyclic pyridine derivatives
CA1317945C (en) * 1985-12-13 1993-05-18 Ulf Fischer Tricyclic pyridazopyridone derivatives
DE3614005A1 (de) * 1986-04-25 1987-10-29 Westfael Elekt Werke Verfahren zur rauchgasentschwefelung
EP0294599A3 (de) * 1987-06-12 1990-05-09 F. Hoffmann-La Roche Ag Tricyclische Pyridonderivate
US6992090B2 (en) * 2003-06-16 2006-01-31 Adolor Corporation Substituted piperidine compounds and methods of their use
US7538110B2 (en) 2005-10-27 2009-05-26 Adolor Corporation Opioid antagonists
US20100311782A1 (en) * 2009-06-08 2010-12-09 Adolor Corporation Substituted piperidinylpropanoic acid compounds and methods of their use
US8143273B2 (en) 2010-06-22 2012-03-27 Hoffman-La Roche Inc. Quinolizidine and indolizidine derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA668487A (en) * 1963-08-13 H. Tilford Charles Hexahydro quinolizines
US3031454A (en) * 1962-04-24 Hexahydro quinolizeses
GB1096589A (en) * 1964-03-31 1967-12-29 Chugai Pharmaceutical Co Ltd Novel quinolizidine derivatives or salts thereof and process for preparing the same
DE1470084A1 (de) * 1964-08-19 1969-05-29 Merck Ag E Verfahren zur Herstellung von substituierten Piperidin-derivaten
US3394141A (en) * 1965-11-12 1968-07-23 Fabio Sparatore Z-benzyaminobenzimidazoles
US3852452A (en) * 1970-02-10 1974-12-03 Ayerst Mckenna & Harrison Benzocycloheptaisoquinoline derivatives as cns depressants
NZ191763A (en) * 1978-10-13 1984-05-31 Hoffmann La Roche 7-beta-phenyl-quinolidines, intermediates and pharmaceutical compositions

Also Published As

Publication number Publication date
ES493198A0 (es) 1981-07-01
US4236010A (en) 1980-11-25
ES8105992A1 (es) 1981-07-01
US4316030A (en) 1982-02-16
CS241050B2 (en) 1986-03-13
FI793182A (fi) 1980-04-14
CA1140927A (en) 1983-02-08
DK433779A (da) 1980-04-14
ES493195A0 (es) 1981-07-01
GR73144B (fi) 1984-02-09
ES493196A0 (es) 1981-07-01
CS613879A2 (en) 1985-06-13
US4338444A (en) 1982-07-06
AR230636A1 (es) 1984-05-31
PH16131A (en) 1983-07-08
ES8105997A1 (es) 1981-07-01
ES8106304A1 (es) 1981-06-16
FI66611B (fi) 1984-07-31
FI70017C (fi) 1986-09-12
ES8105994A1 (es) 1981-07-01
DE2962580D1 (en) 1982-06-03
NO152787B (no) 1985-08-12
ES493199A0 (es) 1981-06-16
ES8105993A1 (es) 1981-07-01
NO152787C (no) 1985-11-20
ES493202A0 (es) 1981-07-01
EP0012170A1 (de) 1980-06-25
DE2966740D1 (de) 1984-04-05
EP0044573A1 (de) 1982-01-27
US4272627A (en) 1981-06-09
FI66611C (fi) 1984-11-12
US4329467A (en) 1982-05-11
IL58415A (en) 1982-11-30
AU5154579A (en) 1980-04-17
AR230637A1 (es) 1984-05-31
ES484930A0 (es) 1981-11-16
HU180249B (en) 1983-02-28
ATE877T1 (de) 1982-05-15
EP0012170B1 (de) 1982-04-21
MC1289A1 (fr) 1980-07-22
EP0044573B1 (de) 1984-02-29
CU35149A (en) 1983-04-06
BR7906543A (pt) 1980-07-15
FI70017B (fi) 1986-01-31
IE791943L (en) 1980-04-13
AU533075B2 (en) 1983-10-27
IL58415A0 (en) 1980-01-31
IE49082B1 (en) 1985-07-24
NO793300L (no) 1980-04-15
US4306067A (en) 1981-12-15
ES8105991A1 (es) 1981-07-01
AR230446A1 (es) 1984-04-30
FI841359A (fi) 1984-04-05
ES8200680A1 (es) 1981-11-16
NZ191763A (en) 1984-05-31
ES493204A0 (es) 1981-07-01
PT70309A (en) 1979-11-01

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE & CO.