ATE239451T1 - Verfahren zur stabilen einarbeitung von substanzen in trockene geschäumte glasmatrizen und auf diese weise hergestellte zusammensetzungen - Google Patents
Verfahren zur stabilen einarbeitung von substanzen in trockene geschäumte glasmatrizen und auf diese weise hergestellte zusammensetzungenInfo
- Publication number
- ATE239451T1 ATE239451T1 AT96917569T AT96917569T ATE239451T1 AT E239451 T1 ATE239451 T1 AT E239451T1 AT 96917569 T AT96917569 T AT 96917569T AT 96917569 T AT96917569 T AT 96917569T AT E239451 T1 ATE239451 T1 AT E239451T1
- Authority
- AT
- Austria
- Prior art keywords
- substances
- way
- compositions produced
- foamed glass
- stable incorporation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/04—Preserving or maintaining viable microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Microbiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Glass Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48604395A | 1995-06-07 | 1995-06-07 | |
| PCT/GB1996/001367 WO1996040077A2 (en) | 1995-06-07 | 1996-06-07 | Methods for stably incorporating substances within dry, foamed glass matrices and compositions obtained thereby |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239451T1 true ATE239451T1 (de) | 2003-05-15 |
Family
ID=23930384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96917569T ATE239451T1 (de) | 1995-06-07 | 1996-06-07 | Verfahren zur stabilen einarbeitung von substanzen in trockene geschäumte glasmatrizen und auf diese weise hergestellte zusammensetzungen |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0831790B1 (de) |
| JP (1) | JP4502406B2 (de) |
| KR (1) | KR19990022710A (de) |
| CN (1) | CN1245957C (de) |
| AP (1) | AP852A (de) |
| AT (1) | ATE239451T1 (de) |
| AU (1) | AU713599B2 (de) |
| BR (1) | BR9609188A (de) |
| CA (1) | CA2223438C (de) |
| CZ (1) | CZ391297A3 (de) |
| DE (1) | DE69628007T2 (de) |
| DK (1) | DK0831790T3 (de) |
| ES (1) | ES2194992T3 (de) |
| HU (1) | HUP9901716A3 (de) |
| IL (1) | IL122482A (de) |
| MX (1) | MX9709716A (de) |
| NO (1) | NO975773L (de) |
| NZ (1) | NZ309841A (de) |
| PL (1) | PL184823B1 (de) |
| PT (1) | PT831790E (de) |
| SK (1) | SK167597A3 (de) |
| WO (1) | WO1996040077A2 (de) |
Families Citing this family (59)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2145418A1 (en) | 1992-09-29 | 1994-04-14 | John S. Patton | Pulmonary delivery of active fragments of parathyroid hormone |
| WO1995024183A1 (en) | 1994-03-07 | 1995-09-14 | Inhale Therapeutic Systems | Methods and compositions for pulmonary delivery of insulin |
| EP0762897B1 (de) | 1994-06-02 | 2003-04-02 | Elan Drug Delivery Limited | Methode zum verhindern der aggregation von proteinen/peptiden bei rehydratation oder auftauen |
| US6964771B1 (en) | 1995-06-07 | 2005-11-15 | Elan Drug Delivery Limited | Method for stably incorporating substances within dry, foamed glass matrices |
| US6509146B1 (en) | 1996-05-29 | 2003-01-21 | Universal Preservation Technologies, Inc. | Scalable long-term shelf preservation of sensitive biological solutions and suspensions |
| US5766520A (en) * | 1996-07-15 | 1998-06-16 | Universal Preservation Technologies, Inc. | Preservation by foam formation |
| US6468782B1 (en) | 1996-12-05 | 2002-10-22 | Quadrant Healthcare (Uk) Limited | Methods of preserving prokaryotic cells and compositions obtained thereby |
| GB9705588D0 (en) | 1997-03-18 | 1997-05-07 | Anglia Research Foundation | Stable particle in liquid formulations |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| EP1032647B1 (de) * | 1997-11-26 | 2006-03-29 | Universal Preservation Technologies, Inc. | Konservierung empfindlicher biologischer proben durch verglasung |
| US6352722B1 (en) | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
| WO1999047174A1 (en) * | 1998-03-18 | 1999-09-23 | Cambridge Biostability Limited | Amorphous glasses for stabilising sensitive products |
| US6306345B1 (en) * | 1998-05-06 | 2001-10-23 | Universal Preservation Technologies, Inc. | Industrial scale barrier technology for preservation of sensitive biological materials at ambient temperatures |
| JP2011025068A (ja) * | 1999-02-22 | 2011-02-10 | Chugai Pharmaceut Co Ltd | プレフィルドシリンジタンパク質溶液製剤 |
| GB9904049D0 (en) * | 1999-02-22 | 1999-04-14 | Quadrant Holdings Cambridge | Rapidly-soluble compositions |
| BR0010249A (pt) * | 1999-05-04 | 2002-02-13 | Eric Edward Worrall | Processo para a preservação de vìrus e micoplasma |
| US6692695B1 (en) | 1999-05-06 | 2004-02-17 | Quadrant Drug Delivery Limited | Industrial scale barrier technology for preservation of sensitive biological materials |
| GB9914412D0 (en) * | 1999-06-22 | 1999-08-18 | Worrall Eric E | Method for the preservation of viruses,bacteria and biomolecules |
| CA2382061A1 (en) * | 1999-08-19 | 2001-02-22 | Victor Bronshtein | Preservation of bacterial cells at ambient temperatures |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| PL203804B1 (pl) * | 2000-06-27 | 2009-11-30 | Hoffmann La Roche | Sposób wytwarzania kompozycji farmaceutycznej w postaci spoistej, płytkowej, piankowej, gąbczastej lub ciastowatej struktury i kompozycja farmaceutyczna otrzymana tym sposobem |
| GB0017999D0 (en) * | 2000-07-21 | 2000-09-13 | Smithkline Beecham Biolog | Novel device |
| US6653062B1 (en) | 2000-07-26 | 2003-11-25 | Wisconsin Alumni Research Foundation | Preservation and storage medium for biological materials |
| US6537666B1 (en) | 2000-10-23 | 2003-03-25 | Universal Preservation Technologies, Inc. | Methods of forming a humidity barrier for the ambient temperature preservation of sensitive biologicals |
| MXPA04004459A (es) * | 2001-11-09 | 2005-05-16 | Johnson & Johnson | Composiciones liofilizadas de anticuerpo monoclonal. |
| ATE508735T1 (de) | 2001-12-19 | 2011-05-15 | Novartis Ag | Pulmonale verabreichung von aminoglykosiden |
| AU2003287980B2 (en) * | 2002-11-01 | 2009-06-25 | Glaxosmithkline Biologicals S.A. | Drying process |
| EP1428526A1 (de) * | 2002-12-13 | 2004-06-16 | Rijksuniversiteit Groningen | Zusammensetzung zur schnellen Freisetzung von lipophilen Stoffen |
| GB0409795D0 (en) * | 2004-04-30 | 2004-06-09 | Glaxosmithkline Biolog Sa | Drying method |
| DE602005016402D1 (de) | 2004-05-24 | 2009-10-15 | Genvault Corp | Stabile lagerung von protein und stabile lagerung von nukleinsäure in wiedergewinnbarer form |
| US9469835B2 (en) | 2004-06-02 | 2016-10-18 | Victor Bronshtein | Preservation by vaporization |
| GB0517688D0 (en) * | 2005-08-31 | 2005-10-05 | Cambridge Biostability Ltd | Improvements in the stabilisation of biological materials |
| GB0523638D0 (en) * | 2005-11-21 | 2005-12-28 | Cambridge Biostability Ltd | Pharmaceutical device for the administration of substances to patients |
| US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| US8097245B2 (en) * | 2005-12-28 | 2012-01-17 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| CA2673120C (en) | 2006-12-18 | 2012-08-07 | Advanced Bionutrition Corporation | A dry food product containing live probiotic |
| BRPI0814594A2 (pt) * | 2007-07-26 | 2015-01-20 | Sanofi Pasteur Ltd | Composições e métodos adjuvantes de antígeno |
| EP2334792B1 (de) | 2008-09-12 | 2020-09-09 | GenTegra LLC | Matrizes und medien zur lagerung und stabilisierung von biomolekülen |
| CA2986751A1 (en) | 2009-03-27 | 2010-09-30 | Intervet International B.V. | Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish |
| EP2435554B1 (de) | 2009-05-26 | 2017-07-26 | Advanced Bionutrition Corporation | Stabile trockenpulverzusammensetzung mit biologisch aktiven mikroorganismen und/oder bioaktiven materialien sowie herstellungsverfahren dafür |
| GB0918450D0 (en) | 2009-10-21 | 2009-12-09 | Innovata Ltd | Composition |
| EP2529004B1 (de) | 2010-01-28 | 2017-06-07 | Advanced Bionutrition Corporation | Trockenglaszusammensetzung mit einem bioaktiven material |
| US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
| CN104147605A (zh) * | 2010-08-13 | 2014-11-19 | 高级生物营养公司 | 用于生物材料的干的贮存稳定用组合物及其制备方法 |
| AU2012222150A1 (en) * | 2011-02-24 | 2013-09-26 | Paxvax, Inc. | Formulations useful for spray drying vaccines |
| KR102374576B1 (ko) * | 2011-05-17 | 2022-03-15 | 솔리제닉스, 인크. | 열안정성 백신 조성물 및 그의 제조방법 |
| EP4088736A1 (de) | 2011-10-25 | 2022-11-16 | Prothena Biosciences Limited | Humanisierte anti-amyloid-antikörper-formulierungen und verfahren |
| GB2498774A (en) | 2012-01-27 | 2013-07-31 | Bruce Roser | Glass-stabilised biological materials and syringe |
| BR112018001784B1 (pt) | 2015-07-29 | 2022-05-10 | Advanced Bionutrition Corp | Composições probióticas secas estáveis para usos dietéticos especiais, seu método de preparação e método de preparação de uma fórmula para bebês |
| ES2963004T3 (es) * | 2015-09-09 | 2024-03-22 | Drawbridge Health Inc | Dispositivos para la recopilación, estabilización y conservación de muestras |
| CN106434840B (zh) * | 2016-12-02 | 2019-08-09 | 北京中检葆泰生物技术有限公司 | 一种用于微生物法定量检测维生素b12的微孔板、其试剂盒及其制备方法 |
| CN106701887B (zh) * | 2017-01-03 | 2020-01-17 | 北京中检葆泰生物技术有限公司 | 一种用于微生物法定量检测叶酸的微孔板、其试剂盒及其制备方法 |
| CN106676160B (zh) * | 2017-01-03 | 2020-02-21 | 北京中检葆泰生物技术有限公司 | 一种用于微生物法定量检测泛酸的微孔板、其试剂盒及其制备方法 |
| CN106591415B (zh) * | 2017-01-03 | 2019-12-10 | 北京中检葆泰生物技术有限公司 | 一种用于微生物法定量检测生物素的微孔板、其试剂盒及其制备方法 |
| CN106676161B (zh) * | 2017-01-03 | 2020-01-21 | 北京中检葆泰生物技术有限公司 | 一种用于微生物法定量检测烟酸的微孔板、其试剂盒及其制备方法 |
| CN210383905U (zh) | 2017-01-10 | 2020-04-24 | 集联健康有限公司 | 一种用于从受试者收集流体样品的装置以及运输套筒 |
| CN118086244B (zh) * | 2023-08-18 | 2024-08-06 | 北京中检葆泰生物技术有限公司 | 一种乳源碱性磷酸酶标准品的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3362830A (en) * | 1966-04-04 | 1968-01-09 | American Mach & Foundry | Preparation of water soluble product |
| JPS57100177A (en) * | 1980-12-16 | 1982-06-22 | Showa Denko Kk | Mixed agent composition of amino acid with saccharide |
| EP0166440A3 (de) * | 1984-06-28 | 1987-06-03 | THE PROCTER & GAMBLE COMPANY | Antacidum |
| GB8604983D0 (en) * | 1986-02-28 | 1986-04-09 | Biocompatibles Ltd | Protein preservation |
| GB8801338D0 (en) * | 1988-01-21 | 1988-02-17 | Quadrant Bioresources Ltd | Preservation of viruses |
| JP3016096B2 (ja) * | 1989-05-01 | 2000-03-06 | バクスター インターナショナル インコーポレーテッド | 有益な薬剤から成る組成物および制御された溶解により該組成物を投与する方法 |
| DE3918051A1 (de) * | 1989-06-02 | 1990-12-06 | Haensel Otto Gmbh | Verfahren zur satzweisen herstellung einer beluefteten suesswarenschaummasse aus einer zuckerloesung und einer aufschlagmittelloesung |
| GB9010742D0 (en) * | 1990-05-14 | 1990-07-04 | Quadrant Bioresources Ltd | Stabilization of biological macromolecular substances |
| JPH06182189A (ja) * | 1991-05-31 | 1994-07-05 | Res Corp Technol Inc | 自己乳化型ガラス |
| JP3164854B2 (ja) * | 1991-10-31 | 2001-05-14 | 雪印乳業株式会社 | 皮膚衛生用シート |
| AU3125193A (en) * | 1991-12-05 | 1993-06-28 | Pitman-Moore, Inc. | A carbohydrate glass matrix for the sustained release of a therapeutic agent |
| ATE147261T1 (de) * | 1992-01-13 | 1997-01-15 | Pfizer | Verfahren zur herstellung von tabletten mit hoher festigkeit |
| US5523106A (en) * | 1994-02-03 | 1996-06-04 | Nabisco, Inc. | Juice-based expanded snacks and process for preparing them |
| JPH10500982A (ja) * | 1994-05-27 | 1998-01-27 | ファーマーク、ネダーランド、ベスローテン、フェンノートシャップ | 医薬組成物 |
-
1996
- 1996-06-07 KR KR1019970709152A patent/KR19990022710A/ko not_active Withdrawn
- 1996-06-07 JP JP50023597A patent/JP4502406B2/ja not_active Expired - Lifetime
- 1996-06-07 CN CNB961946172A patent/CN1245957C/zh not_active Expired - Fee Related
- 1996-06-07 WO PCT/GB1996/001367 patent/WO1996040077A2/en not_active Ceased
- 1996-06-07 SK SK1675-97A patent/SK167597A3/sk unknown
- 1996-06-07 AT AT96917569T patent/ATE239451T1/de not_active IP Right Cessation
- 1996-06-07 CA CA002223438A patent/CA2223438C/en not_active Expired - Fee Related
- 1996-06-07 AU AU60098/96A patent/AU713599B2/en not_active Ceased
- 1996-06-07 AP APAP/P/1997/001151A patent/AP852A/en active
- 1996-06-07 EP EP96917569A patent/EP0831790B1/de not_active Revoked
- 1996-06-07 NZ NZ309841A patent/NZ309841A/en not_active IP Right Cessation
- 1996-06-07 ES ES96917569T patent/ES2194992T3/es not_active Expired - Lifetime
- 1996-06-07 DK DK96917569T patent/DK0831790T3/da active
- 1996-06-07 PT PT96917569T patent/PT831790E/pt unknown
- 1996-06-07 MX MX9709716A patent/MX9709716A/es not_active IP Right Cessation
- 1996-06-07 IL IL12248296A patent/IL122482A/xx not_active IP Right Cessation
- 1996-06-07 BR BR9609188A patent/BR9609188A/pt not_active IP Right Cessation
- 1996-06-07 HU HU9901716A patent/HUP9901716A3/hu unknown
- 1996-06-07 DE DE69628007T patent/DE69628007T2/de not_active Expired - Fee Related
- 1996-06-07 CZ CZ973912A patent/CZ391297A3/cs unknown
- 1996-06-07 PL PL96323902A patent/PL184823B1/pl not_active IP Right Cessation
-
1997
- 1997-12-08 NO NO975773A patent/NO975773L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| MX9709716A (es) | 1998-03-31 |
| IL122482A (en) | 1999-10-28 |
| IL122482A0 (en) | 1998-06-15 |
| CA2223438C (en) | 2008-05-13 |
| KR19990022710A (ko) | 1999-03-25 |
| DE69628007D1 (de) | 2003-06-12 |
| WO1996040077A3 (en) | 1997-01-23 |
| HUP9901716A3 (en) | 2000-04-28 |
| AP852A (en) | 2000-06-16 |
| PT831790E (pt) | 2003-07-31 |
| EP0831790B1 (de) | 2003-05-07 |
| SK167597A3 (en) | 1998-10-07 |
| NO975773D0 (no) | 1997-12-08 |
| DE69628007T2 (de) | 2003-11-27 |
| CN1193908A (zh) | 1998-09-23 |
| PL184823B1 (pl) | 2002-12-31 |
| PL323902A1 (en) | 1998-04-27 |
| AU713599B2 (en) | 1999-12-09 |
| EP0831790A2 (de) | 1998-04-01 |
| HUP9901716A2 (hu) | 1999-09-28 |
| NZ309841A (en) | 1999-10-28 |
| NO975773L (no) | 1998-02-03 |
| CN1245957C (zh) | 2006-03-22 |
| JP4502406B2 (ja) | 2010-07-14 |
| AU6009896A (en) | 1996-12-30 |
| ES2194992T3 (es) | 2003-12-01 |
| CZ391297A3 (cs) | 1998-05-13 |
| WO1996040077A2 (en) | 1996-12-19 |
| CA2223438A1 (en) | 1996-12-19 |
| AP9701151A0 (en) | 1998-01-31 |
| DK0831790T3 (da) | 2003-09-01 |
| JPH11506467A (ja) | 1999-06-08 |
| BR9609188A (pt) | 1999-05-11 |
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