ATE238271T1 - Desformoterol und verfahren zu seiner herstellung - Google Patents
Desformoterol und verfahren zu seiner herstellungInfo
- Publication number
- ATE238271T1 ATE238271T1 AT99930556T AT99930556T ATE238271T1 AT E238271 T1 ATE238271 T1 AT E238271T1 AT 99930556 T AT99930556 T AT 99930556T AT 99930556 T AT99930556 T AT 99930556T AT E238271 T1 ATE238271 T1 AT E238271T1
- Authority
- AT
- Austria
- Prior art keywords
- desformoterol
- production
- amino
- disclosed
- benzenemethanol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/103,212 US5965622A (en) | 1998-06-23 | 1998-06-23 | Desformoterol and process for its preparation |
| PCT/US1999/014082 WO1999067198A1 (en) | 1998-06-23 | 1999-06-22 | Desformoterol and process for its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE238271T1 true ATE238271T1 (de) | 2003-05-15 |
Family
ID=22293976
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99930556T ATE238271T1 (de) | 1998-06-23 | 1999-06-22 | Desformoterol und verfahren zu seiner herstellung |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US5965622A (de) |
| EP (1) | EP1093450B1 (de) |
| JP (1) | JP4328021B2 (de) |
| AT (1) | ATE238271T1 (de) |
| AU (1) | AU747329B2 (de) |
| CA (1) | CA2335154C (de) |
| DE (1) | DE69907190T2 (de) |
| ES (1) | ES2193722T3 (de) |
| WO (1) | WO1999067198A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20010428A1 (it) * | 2001-03-02 | 2002-09-02 | Chemo Breath S A | Composizioni ad uso inalatorio a base di formoterolo |
| US20030055026A1 (en) * | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
| US6667344B2 (en) | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
| US20040023935A1 (en) * | 2002-08-02 | 2004-02-05 | Dey, L.P. | Inhalation compositions, methods of use thereof, and process for preparation of same |
| KR101369631B1 (ko) * | 2002-08-21 | 2014-03-05 | 노턴 헬스케어 리미티드 | 흡입용 조성물 |
| GB0219511D0 (en) * | 2002-08-21 | 2002-10-02 | Norton Healthcare Ltd | Method of preparing dry powder inhalation compositions |
| US20050158248A1 (en) * | 2002-08-21 | 2005-07-21 | Xian-Ming Zeng | Method of preparing dry powder inhalation compositions |
| US20040109826A1 (en) * | 2002-12-06 | 2004-06-10 | Dey, L.P. | Stabilized albuterol compositions and method of preparation thereof |
| TWI359675B (en) * | 2003-07-10 | 2012-03-11 | Dey L P | Bronchodilating β-agonist compositions |
| WO2008035380A2 (en) * | 2006-09-19 | 2008-03-27 | Natco Pharma Limited | An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts |
| CN101391962A (zh) * | 2007-09-21 | 2009-03-25 | 北京德众万全药物技术开发有限公司 | 一种高纯度的(R)-α-(溴甲基)-4-苄氧基-3-硝基苯甲醇及其制备方法 |
| CN101462971B (zh) * | 2007-12-19 | 2014-05-07 | 北京德众万全药物技术开发有限公司 | 高纯度的用于制备福莫特罗的关键中间体及其制备方法 |
| EP2285770B1 (de) | 2008-06-02 | 2015-05-20 | Cipla Limited | Verfahren zur herstellung von arformoterol |
| US20110313199A1 (en) | 2008-12-26 | 2011-12-22 | Actavis Group Ptc Ehf | processes for preparing substantially pure arformoterol and its intermediates |
| US8282512B1 (en) | 2009-03-26 | 2012-10-09 | Warrior Sports, Inc. | Lacrosse head |
| CN101921200B (zh) * | 2009-06-16 | 2014-01-15 | 上海医药工业研究院 | 一种n-苄基-1-(4-甲氧基苯基)-2-丙胺的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2031407A6 (es) * | 1988-10-05 | 1992-12-01 | Lasa Lab | Mejoras introducidas en el objeto de la patente principal n{ 8703715 por: procedimiento de obtencion de n-(2-hidroxi-5-(1-hidroxi-2-((2-(4-metoxifenil)-1-metiletil)amino)etil)fenil)formamida". |
-
1998
- 1998-06-23 US US09/103,212 patent/US5965622A/en not_active Expired - Lifetime
-
1999
- 1999-05-05 US US09/305,534 patent/US6071971A/en not_active Expired - Lifetime
- 1999-06-22 DE DE69907190T patent/DE69907190T2/de not_active Expired - Lifetime
- 1999-06-22 JP JP2000555854A patent/JP4328021B2/ja not_active Expired - Lifetime
- 1999-06-22 ES ES99930556T patent/ES2193722T3/es not_active Expired - Lifetime
- 1999-06-22 WO PCT/US1999/014082 patent/WO1999067198A1/en active IP Right Grant
- 1999-06-22 AT AT99930556T patent/ATE238271T1/de not_active IP Right Cessation
- 1999-06-22 EP EP99930556A patent/EP1093450B1/de not_active Expired - Lifetime
- 1999-06-22 CA CA002335154A patent/CA2335154C/en not_active Expired - Lifetime
- 1999-06-22 AU AU47072/99A patent/AU747329B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA2335154C (en) | 2008-11-18 |
| AU4707299A (en) | 2000-01-10 |
| JP4328021B2 (ja) | 2009-09-09 |
| DE69907190T2 (de) | 2004-02-12 |
| CA2335154A1 (en) | 1999-12-29 |
| US5965622A (en) | 1999-10-12 |
| WO1999067198A1 (en) | 1999-12-29 |
| JP2002518468A (ja) | 2002-06-25 |
| AU747329B2 (en) | 2002-05-16 |
| EP1093450A1 (de) | 2001-04-25 |
| ES2193722T3 (es) | 2003-11-01 |
| US6071971A (en) | 2000-06-06 |
| EP1093450B1 (de) | 2003-04-23 |
| DE69907190D1 (de) | 2003-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |