ATE237138T1 - Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen - Google Patents
Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffenInfo
- Publication number
- ATE237138T1 ATE237138T1 AT97904060T AT97904060T ATE237138T1 AT E237138 T1 ATE237138 T1 AT E237138T1 AT 97904060 T AT97904060 T AT 97904060T AT 97904060 T AT97904060 T AT 97904060T AT E237138 T1 ATE237138 T1 AT E237138T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrophobic
- groups
- conformatively
- fluorophore
- create
- Prior art date
Links
- 230000002209 hydrophobic effect Effects 0.000 title abstract 3
- 229920000642 polymer Polymers 0.000 title 1
- PVVYECWIEUSSDK-UHFFFAOYSA-O 1-(2-phenylethenyl)pyridin-1-ium-2-amine Chemical compound NC1=CC=CC=[N+]1C=CC1=CC=CC=C1 PVVYECWIEUSSDK-UHFFFAOYSA-O 0.000 abstract 1
- 229920000858 Cyclodextrin Polymers 0.000 abstract 1
- 238000000684 flow cytometry Methods 0.000 abstract 1
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B69/00—Dyes not provided for by a single group of this subclass
- C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/141111—Diverse hetero atoms in same or different rings [e.g., alkaloids, opiates, etc.]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/18—Sulfur containing
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/595,092 US5994143A (en) | 1996-02-01 | 1996-02-01 | Polymeric fluorophores enhanced by moieties providing a hydrophobic and conformationally restrictive microenvironment |
| PCT/US1997/001429 WO1997028447A1 (en) | 1996-02-01 | 1997-01-30 | Polymeric fluorophores enhanced by moieties providing a hydrophobic and conformationally restrictive microenvironment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE237138T1 true ATE237138T1 (de) | 2003-04-15 |
Family
ID=24381697
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97904060T ATE237138T1 (de) | 1996-02-01 | 1997-01-30 | Durch gruppen erweiterte fluorophore polymere, die eine hydrophobe und konformativ eingeschrankte mikroumgebung schaffen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5994143A (OSRAM) |
| EP (1) | EP1019722B1 (OSRAM) |
| JP (1) | JP4255514B2 (OSRAM) |
| AT (1) | ATE237138T1 (OSRAM) |
| DE (1) | DE69720809T2 (OSRAM) |
| ES (1) | ES2197332T3 (OSRAM) |
| WO (1) | WO1997028447A1 (OSRAM) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6437099B1 (en) * | 1998-01-07 | 2002-08-20 | Hamamatsu Photonics K.K. | Fluorescene—activating antisera and IgG fraction therefrom |
| JP3437094B2 (ja) * | 1998-07-03 | 2003-08-18 | 松下電器産業株式会社 | 多波長蛍光偏光法 |
| US8323903B2 (en) * | 2001-10-12 | 2012-12-04 | Life Technologies Corporation | Antibody complexes and methods for immunolabeling |
| US20050069962A1 (en) | 2001-10-12 | 2005-03-31 | Archer Robert M | Antibody complexes and methods for immunolabeling |
| DE10331093A1 (de) * | 2003-07-09 | 2005-02-10 | Schering Ag | Vorrichtung und Verfahren zur direkten quantitativen in vitro-Bestimmung einer in einer Probe enthaltenen Substanz |
| US20050233465A1 (en) * | 2004-04-14 | 2005-10-20 | Bioprocessors Corp. | Compositions of matter useful as pH indicators and related methods |
| DE102004033050A1 (de) * | 2004-07-08 | 2006-01-26 | International University Bremen Gmbh | Photostabilisierung von Fluoreszenzfarbstoffen |
| WO2007053594A2 (en) * | 2005-10-31 | 2007-05-10 | Clontech Laboratories, Inc. | Large dynamic range proteomic analysis methods and compositions for practicing the same |
| US7781187B2 (en) * | 2005-12-30 | 2010-08-24 | Corning Incorporated | Fluorescent dyes |
| GB2437545B (en) * | 2006-04-28 | 2011-07-06 | Novexin Ltd | Dextrin-containing reagents for detecting and quantifying proteins |
| JP2013040136A (ja) * | 2011-08-17 | 2013-02-28 | Tosoh Corp | 4−アルコキシ−2−(4−アミノスチリル)ベンゾチアゾリウム塩、その製造方法およびそれを用いる核酸の検出方法 |
| US9765220B2 (en) | 2013-08-22 | 2017-09-19 | Sony Corporation | Water soluble fluorescent or colored dyes and methods for their use |
| CN103525117A (zh) * | 2013-10-30 | 2014-01-22 | 苏州大学 | 一种半花菁荧光染料、制备方法及应用 |
| JP6464534B2 (ja) * | 2014-08-02 | 2019-02-06 | エルジー・ケム・リミテッド | 染料複合体、光変換フィルムおよびそれを含む電子素子 |
| CN107454903B (zh) | 2015-02-26 | 2021-01-01 | 索尼公司 | 包含共轭基团的水溶性荧光或着色染料 |
| CN104788991B (zh) * | 2015-03-04 | 2017-01-25 | 苏州大学 | 一种二氯三嗪反应基半花菁荧光活性染料及其制备方法 |
| BR112018070164B1 (pt) | 2016-04-01 | 2022-09-27 | Sony Corporation Of America | Corantes diméricos ou poliméricos ultrabrilhantes |
| US11434377B2 (en) | 2016-04-01 | 2022-09-06 | Sony Corporation | Ultra bright dimeric or polymeric dyes with rigid spacing groups |
| US9851359B2 (en) | 2016-04-06 | 2017-12-26 | Sony Corporation Of America | Ultra bright dimeric or polymeric dyes with spacing linker groups |
| EP3455238A1 (en) | 2016-05-10 | 2019-03-20 | Sony Corporation | Ultra bright polymeric dyes with peptide backbones |
| WO2017197014A2 (en) * | 2016-05-10 | 2017-11-16 | Sony Corporation | Compositions comprising a polymeric dye and a cyclodextrin and uses thereof |
| BR112018073199A2 (pt) | 2016-05-11 | 2019-04-16 | Sony Corporation | corantes diméricos ou poliméricos ultrabrilhantes |
| JP7068191B2 (ja) | 2016-06-06 | 2022-05-16 | ソニーグループ株式会社 | 蛍光または有色レポーター基を含むイオン性ポリマー |
| US12018159B2 (en) | 2016-07-29 | 2024-06-25 | Sony Group Corporation | Ultra bright dimeric or polymeric dyes and methods for preparation of the same |
| KR20200067132A (ko) | 2017-10-05 | 2020-06-11 | 소니 주식회사 | 프로그램가능한 중합체성 약물 |
| KR20200064059A (ko) | 2017-10-05 | 2020-06-05 | 소니 주식회사 | 프로그램가능한 수지상 약물 |
| CN111836645A (zh) | 2017-11-16 | 2020-10-27 | 索尼公司 | 可编程的聚合药物 |
| CN111565756A (zh) | 2018-01-12 | 2020-08-21 | 索尼公司 | 包含生物活性化合物的具有刚性间隔基团的聚合物 |
| EP4616912A3 (en) | 2018-01-12 | 2025-11-19 | Sony Group Corporation | Phosphoalkyl ribose polymers comprising biologically active compounds |
| EP3769085B1 (en) | 2018-03-19 | 2022-08-24 | Sony Group Corporation | Use of divalent metals for enhancement of fluorescent signals |
| KR102864292B1 (ko) | 2018-03-21 | 2025-09-26 | 소니그룹주식회사 | 링커 군을 갖는 중합체성 텐덤 염료 |
| JP7580689B2 (ja) | 2018-06-27 | 2024-11-12 | ソニーグループ株式会社 | デオキシリボースを含むリンカー基を有するポリマー色素 |
| CN113383043A (zh) | 2019-09-26 | 2021-09-10 | 索尼集团公司 | 具有连接体基团的聚合物串联染料 |
| CN111500110B (zh) * | 2020-04-28 | 2022-09-06 | 陕西大风印务科技有限公司 | 烟用包装纸用透明油墨及其涂层、烟用包装纸 |
| US20240132725A1 (en) | 2020-12-07 | 2024-04-25 | Sony Group Corporation | Spacing linker group design for brightness enhancement in dimeric or polymeric dyes |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4619990A (en) * | 1985-03-11 | 1986-10-28 | Minnesota Mining And Manufacturing Company | Polymeric dyes with pendent chromophore groups capable of undergoing thermoplastic deformation |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5002883A (en) * | 1987-10-30 | 1991-03-26 | Abbott Laboratories | Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents |
| CA1323293C (en) * | 1987-12-11 | 1993-10-19 | Keith C. Backman | Assay using template-dependent nucleic acid probe reorganization |
| DE3921498A1 (de) * | 1988-09-28 | 1990-03-29 | Bayer Ag | Polymer-gebundene-farbstoffe, verfahren zu deren herstellung und verwendung |
| US5401469A (en) * | 1989-04-19 | 1995-03-28 | Ibiden Co., Ltd. | Plastic optical biomaterials assay device |
| EP0439182B1 (en) * | 1990-01-26 | 1996-04-24 | Abbott Laboratories | Improved method of amplifying target nucleic acids applicable to both polymerase and ligase chain reactions |
| US5401847A (en) * | 1990-03-14 | 1995-03-28 | Regents Of The University Of California | DNA complexes with dyes designed for energy transfer as fluorescent markers |
| DE4114482A1 (de) * | 1991-05-03 | 1992-11-05 | Bayer Ag | Polymere farbstoffe, verfahren zu deren herstellung und deren verwendung |
| WO1992020746A1 (en) * | 1991-05-14 | 1992-11-26 | Hybritech, Incorporated | Polymeric compositions having bound antibodies |
| JPH09500411A (ja) * | 1993-07-13 | 1997-01-14 | アボツト・ラボラトリーズ | 蛍光性ポリマー標識された接合体および中間体 |
-
1996
- 1996-02-01 US US08/595,092 patent/US5994143A/en not_active Expired - Lifetime
-
1997
- 1997-01-30 DE DE69720809T patent/DE69720809T2/de not_active Expired - Fee Related
- 1997-01-30 EP EP97904060A patent/EP1019722B1/en not_active Expired - Lifetime
- 1997-01-30 AT AT97904060T patent/ATE237138T1/de not_active IP Right Cessation
- 1997-01-30 JP JP52779397A patent/JP4255514B2/ja not_active Expired - Fee Related
- 1997-01-30 WO PCT/US1997/001429 patent/WO1997028447A1/en not_active Ceased
- 1997-01-30 ES ES97904060T patent/ES2197332T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1019722B1 (en) | 2003-04-09 |
| DE69720809T2 (de) | 2004-04-01 |
| EP1019722A1 (en) | 2000-07-19 |
| DE69720809D1 (de) | 2003-05-15 |
| WO1997028447A1 (en) | 1997-08-07 |
| US5994143A (en) | 1999-11-30 |
| JP4255514B2 (ja) | 2009-04-15 |
| JP2000509412A (ja) | 2000-07-25 |
| ES2197332T3 (es) | 2004-01-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1019722 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |