ATE236401T1 - Surrogate für bindemoleküle und verbesserte referenzpanele - Google Patents

Surrogate für bindemoleküle und verbesserte referenzpanele

Info

Publication number
ATE236401T1
ATE236401T1 AT95906754T AT95906754T ATE236401T1 AT E236401 T1 ATE236401 T1 AT E236401T1 AT 95906754 T AT95906754 T AT 95906754T AT 95906754 T AT95906754 T AT 95906754T AT E236401 T1 ATE236401 T1 AT E236401T1
Authority
AT
Austria
Prior art keywords
reactivity
panels
receptor
panel
members
Prior art date
Application number
AT95906754T
Other languages
English (en)
Inventor
Lawrence M Kauvar
Hugo O Villar
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/177,673 external-priority patent/US5587293A/en
Application filed by Telik Inc filed Critical Telik Inc
Application granted granted Critical
Publication of ATE236401T1 publication Critical patent/ATE236401T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Laminated Bodies (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Control Of Driving Devices And Active Controlling Of Vehicle (AREA)
  • Forklifts And Lifting Vehicles (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
AT95906754T 1994-01-06 1995-01-05 Surrogate für bindemoleküle und verbesserte referenzpanele ATE236401T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/177,673 US5587293A (en) 1994-01-06 1994-01-06 Method to identify binding partners
US08/308,813 US5798275A (en) 1994-01-06 1994-09-19 Profiling reference panel enriched by non-IG proteins
PCT/US1995/000081 WO1995018969A1 (en) 1994-01-06 1995-01-05 Surrogates for targets and improved reference panels

Publications (1)

Publication Number Publication Date
ATE236401T1 true ATE236401T1 (de) 2003-04-15

Family

ID=26873529

Family Applications (2)

Application Number Title Priority Date Filing Date
AT95906754T ATE236401T1 (de) 1994-01-06 1995-01-05 Surrogate für bindemoleküle und verbesserte referenzpanele
AT02009879T ATE359509T1 (de) 1994-01-06 1995-01-05 Ersatz für zielobjekte und verbesserten referenzplatten

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT02009879T ATE359509T1 (de) 1994-01-06 1995-01-05 Ersatz für zielobjekte und verbesserten referenzplatten

Country Status (11)

Country Link
US (1) US5741653A (de)
EP (1) EP0738390B1 (de)
JP (1) JPH09507300A (de)
AT (2) ATE236401T1 (de)
AU (1) AU700497B2 (de)
CA (1) CA2178096C (de)
DE (2) DE69535463T2 (de)
DK (2) DK1235072T3 (de)
ES (2) ES2284743T3 (de)
PT (1) PT738390E (de)
WO (1) WO1995018969A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2203782T3 (es) 1996-01-17 2004-04-16 Imperial College Innovations Limited Inmunoterapia que utiliza linfocitos t citotoxicos (ctl).
US6054286A (en) * 1996-06-18 2000-04-25 Telik, Inc. Methods to identify immunomodulators using cognate interaction of PKC-theta
WO1998029744A2 (en) * 1997-01-03 1998-07-09 Telik, Inc. Method to classify gene products
US5858694A (en) * 1997-05-30 1999-01-12 Cell Pathways, Inc. Method for identifying compounds for inhibition of cancerous lesions
CA2238283C (en) * 1997-05-30 2002-08-20 Cell Pathways, Inc. Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions
IL136046A0 (en) 1997-11-12 2001-05-20 Dimensional Pharm Inc Methods for classifying proteins
CN1285001A (zh) * 1997-12-18 2001-02-21 塞普拉科有限公司 同时鉴定新型生物靶和用于药物开发的引导结构的方法
US6410584B1 (en) 1998-01-14 2002-06-25 Cell Pathways, Inc. Method for inhibiting neoplastic cells with indole derivatives
IL141107A0 (en) * 1998-08-05 2002-02-10 Univ Pittsburgh A method for determining the tendency for metabolism of a compound by an enzyme
US6625547B1 (en) 1998-08-05 2003-09-23 Washington State University Research Foundation Relative rates of cytochrome p450 metabolism
DE69933679T2 (de) * 1998-08-12 2007-08-23 Zycos Inc., Cambridge Darstellung des profils und katalogisierung von exprimierten proteinmarkern
US20040224338A1 (en) * 1998-08-12 2004-11-11 Zycos Inc., A Delaware Corporation Profiling and cataloging expressed protein tags
US6200771B1 (en) 1998-10-15 2001-03-13 Cell Pathways, Inc. Method of using a novel phosphodiesterase in pharmaceutical screeing to identify compounds for treatment of neoplasia
US6569631B1 (en) 1998-11-12 2003-05-27 3-Dimensional Pharmaceuticals, Inc. Microplate thermal shift assay for ligand development using 5-(4″dimethylaminophenyl)-2-(4′-phenyl)oxazole derivative fluorescent dyes
US6133271A (en) * 1998-11-19 2000-10-17 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives
US6187779B1 (en) 1998-11-20 2001-02-13 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to 2,8-disubstituted quinazoline derivatives
US6369092B1 (en) 1998-11-23 2002-04-09 Cell Pathways, Inc. Method for treating neoplasia by exposure to substituted benzimidazole derivatives
US6077842A (en) * 1998-11-24 2000-06-20 Cell Pathways, Inc. Method of inhibiting neoplastic cells with pyrazolopyridylpyridazinone derivatives
US6034099A (en) * 1998-11-24 2000-03-07 Cell Pathways, Inc. Method for inhibiting neoplastic lesions by administering 4-(arylmethylene)- 2, 3- dihydro-pyrazol-3-ones
US6486155B1 (en) 1998-11-24 2002-11-26 Cell Pathways Inc Method of inhibiting neoplastic cells with isoquinoline derivatives
US6875575B1 (en) 1998-11-25 2005-04-05 Osi Pharmaceuticals, Inc. Diagnostic methods for neoplasia
US6025394A (en) 1999-01-29 2000-02-15 Cell Pathways, Inc. Method for treating patients with acne by administering substituted sulfonyl indenyl acetic acids, amides and alcohols
US6020379A (en) * 1999-02-19 2000-02-01 Cell Pathways, Inc. Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia
EP3712897A1 (de) * 2019-03-22 2020-09-23 Tata Consultancy Services Limited Automatisierte vorhersage der biologischen reaktion von chemischen verbindungen auf der basis chemischer informationen

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE152244T1 (de) * 1987-10-13 1997-05-15 Terrapin Tech Inc Verfahren zur herstellung von imunodiagnose- mitteln
US4963263A (en) * 1988-03-24 1990-10-16 Terrapin Technologies, Inc. Method of identity analyte-binding peptides
US5217869A (en) * 1987-10-13 1993-06-08 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5300425A (en) * 1987-10-13 1994-04-05 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5133866A (en) * 1988-03-24 1992-07-28 Terrapin Technologies, Inc. Method to identify analyte-bending ligands
US5338659A (en) * 1991-04-02 1994-08-16 Terrapin Technologies, Inc. Method for determining analyte concentration by cross-reactivity profiling
US5340474A (en) * 1988-03-24 1994-08-23 Terrapin Technologies, Inc. Panels of analyte-binding ligands
EP0557276A1 (de) * 1989-12-29 1993-09-01 University Technologies International Inc. (Uti) Verfahren zur modellierung von tertiärstrukturen von biologisch aktiven liganden einschliesslich ihrer agonisten und antagonisten und neue synthetische antagonisten auf angiotensinbasis
JPH06502723A (ja) * 1990-11-09 1994-03-24 ヴェリジェン，インコーポレーテッド 抗体を検出する分析系の感度及び／又は特異性の決定方法

Also Published As

Publication number Publication date
EP0738390A1 (de) 1996-10-23
DK0738390T3 (da) 2003-07-21
DE69530179D1 (de) 2003-05-08
US5741653A (en) 1998-04-21
PT738390E (pt) 2003-07-31
DE69535463T2 (de) 2008-01-03
CA2178096A1 (en) 1995-07-13
WO1995018969A1 (en) 1995-07-13
DK1235072T3 (da) 2007-07-16
EP0738390B1 (de) 2003-04-02
AU700497B2 (en) 1999-01-07
AU1522195A (en) 1995-08-01
JPH09507300A (ja) 1997-07-22
DE69535463D1 (de) 2007-05-24
ES2284743T3 (es) 2007-11-16
DE69530179T2 (de) 2004-04-08
ES2196056T3 (es) 2003-12-16
ATE359509T1 (de) 2007-05-15
CA2178096C (en) 2004-03-09

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