DE69530179D1 - Surrogate für bindemoleküle und verbesserte referenzpanele - Google Patents

Surrogate für bindemoleküle und verbesserte referenzpanele

Info

Publication number
DE69530179D1
DE69530179D1 DE69530179T DE69530179T DE69530179D1 DE 69530179 D1 DE69530179 D1 DE 69530179D1 DE 69530179 T DE69530179 T DE 69530179T DE 69530179 T DE69530179 T DE 69530179T DE 69530179 D1 DE69530179 D1 DE 69530179D1
Authority
DE
Germany
Prior art keywords
reactivity
panels
receptor
panel
members
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69530179T
Other languages
English (en)
Other versions
DE69530179T2 (de
Inventor
M Kauvar
O Villar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Telik Inc
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/177,673 external-priority patent/US5587293A/en
Application filed by Telik Inc filed Critical Telik Inc
Publication of DE69530179D1 publication Critical patent/DE69530179D1/de
Application granted granted Critical
Publication of DE69530179T2 publication Critical patent/DE69530179T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Laminated Bodies (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Control Of Driving Devices And Active Controlling Of Vehicle (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Forklifts And Lifting Vehicles (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
DE69530179T 1994-01-06 1995-01-05 Surrogate für bindemoleküle und verbesserte referenzpanele Expired - Fee Related DE69530179T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US177673 1980-08-13
US08/177,673 US5587293A (en) 1994-01-06 1994-01-06 Method to identify binding partners
US308813 1994-09-19
US08/308,813 US5798275A (en) 1994-01-06 1994-09-19 Profiling reference panel enriched by non-IG proteins
PCT/US1995/000081 WO1995018969A1 (en) 1994-01-06 1995-01-05 Surrogates for targets and improved reference panels

Publications (2)

Publication Number Publication Date
DE69530179D1 true DE69530179D1 (de) 2003-05-08
DE69530179T2 DE69530179T2 (de) 2004-04-08

Family

ID=26873529

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69530179T Expired - Fee Related DE69530179T2 (de) 1994-01-06 1995-01-05 Surrogate für bindemoleküle und verbesserte referenzpanele
DE69535463T Expired - Fee Related DE69535463T2 (de) 1994-01-06 1995-01-05 Ersatz für Zielobjekte und verbesserte Referenzplatten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69535463T Expired - Fee Related DE69535463T2 (de) 1994-01-06 1995-01-05 Ersatz für Zielobjekte und verbesserte Referenzplatten

Country Status (11)

Country Link
US (1) US5741653A (de)
EP (1) EP0738390B1 (de)
JP (1) JPH09507300A (de)
AT (2) ATE359509T1 (de)
AU (1) AU700497B2 (de)
CA (1) CA2178096C (de)
DE (2) DE69530179T2 (de)
DK (2) DK0738390T3 (de)
ES (2) ES2284743T3 (de)
PT (1) PT738390E (de)
WO (1) WO1995018969A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE244300T1 (de) 1996-01-17 2003-07-15 Imp College Innovations Ltd Immunotherapie mit verwendung von zytotoxischen t lymphozyten (ctl)
US6054286A (en) * 1996-06-18 2000-04-25 Telik, Inc. Methods to identify immunomodulators using cognate interaction of PKC-theta
AU5902098A (en) * 1997-01-03 1998-07-31 Terrapin Technologies, Inc. Method to classify gene products
CA2238283C (en) * 1997-05-30 2002-08-20 Cell Pathways, Inc. Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions
US5858694A (en) * 1997-05-30 1999-01-12 Cell Pathways, Inc. Method for identifying compounds for inhibition of cancerous lesions
US20010003648A1 (en) 1997-11-12 2001-06-14 Michael W. Pantoliano High throughput method for functionally classifying proteins identified using a genomics approach
CN1285001A (zh) * 1997-12-18 2001-02-21 塞普拉科有限公司 同时鉴定新型生物靶和用于药物开发的引导结构的方法
US6410584B1 (en) 1998-01-14 2002-06-25 Cell Pathways, Inc. Method for inhibiting neoplastic cells with indole derivatives
AU5337599A (en) * 1998-08-05 2000-02-28 University Of Pittsburgh Modelling organic compound reactivity in cytochrome p450 mediated reactions
US6625547B1 (en) 1998-08-05 2003-09-23 Washington State University Research Foundation Relative rates of cytochrome p450 metabolism
ATE343132T1 (de) * 1998-08-12 2006-11-15 Zycos Inc Darstellung des profils und katalogisierung von exprimierten proteinmarkern
US20040224338A1 (en) * 1998-08-12 2004-11-11 Zycos Inc., A Delaware Corporation Profiling and cataloging expressed protein tags
US6200771B1 (en) 1998-10-15 2001-03-13 Cell Pathways, Inc. Method of using a novel phosphodiesterase in pharmaceutical screeing to identify compounds for treatment of neoplasia
US6569631B1 (en) 1998-11-12 2003-05-27 3-Dimensional Pharmaceuticals, Inc. Microplate thermal shift assay for ligand development using 5-(4″dimethylaminophenyl)-2-(4′-phenyl)oxazole derivative fluorescent dyes
US6133271A (en) * 1998-11-19 2000-10-17 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives
US6187779B1 (en) 1998-11-20 2001-02-13 Cell Pathways, Inc. Method for inhibiting neoplastic cells and related conditions by exposure to 2,8-disubstituted quinazoline derivatives
US6369092B1 (en) 1998-11-23 2002-04-09 Cell Pathways, Inc. Method for treating neoplasia by exposure to substituted benzimidazole derivatives
US6486155B1 (en) 1998-11-24 2002-11-26 Cell Pathways Inc Method of inhibiting neoplastic cells with isoquinoline derivatives
US6077842A (en) * 1998-11-24 2000-06-20 Cell Pathways, Inc. Method of inhibiting neoplastic cells with pyrazolopyridylpyridazinone derivatives
US6034099A (en) * 1998-11-24 2000-03-07 Cell Pathways, Inc. Method for inhibiting neoplastic lesions by administering 4-(arylmethylene)- 2, 3- dihydro-pyrazol-3-ones
US6875575B1 (en) 1998-11-25 2005-04-05 Osi Pharmaceuticals, Inc. Diagnostic methods for neoplasia
US6025394A (en) 1999-01-29 2000-02-15 Cell Pathways, Inc. Method for treating patients with acne by administering substituted sulfonyl indenyl acetic acids, amides and alcohols
US6020379A (en) * 1999-02-19 2000-02-01 Cell Pathways, Inc. Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia
EP3712897A1 (de) * 2019-03-22 2020-09-23 Tata Consultancy Services Limited Automatisierte vorhersage der biologischen reaktion von chemischen verbindungen auf der basis chemischer informationen

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE81146B1 (en) * 1987-10-13 2000-05-03 Terrapin Tech Inc Method to produce immunodiagnostic reagents
US5300425A (en) * 1987-10-13 1994-04-05 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5338659A (en) * 1991-04-02 1994-08-16 Terrapin Technologies, Inc. Method for determining analyte concentration by cross-reactivity profiling
US5217869A (en) * 1987-10-13 1993-06-08 Terrapin Technologies, Inc. Method to produce immunodiagnostic reagents
US5133866A (en) * 1988-03-24 1992-07-28 Terrapin Technologies, Inc. Method to identify analyte-bending ligands
US4963263A (en) * 1988-03-24 1990-10-16 Terrapin Technologies, Inc. Method of identity analyte-binding peptides
US5340474A (en) * 1988-03-24 1994-08-23 Terrapin Technologies, Inc. Panels of analyte-binding ligands
WO1991010140A2 (en) * 1989-12-29 1991-07-11 University Technologies International Inc. Methods for modelling tertiary structures of biologically active ligands including agonists and antagonists thereto and novel synthetic antagonists based on angiotensin
JPH06502723A (ja) * 1990-11-09 1994-03-24 ヴェリジェン，インコーポレーテッド 抗体を検出する分析系の感度及び／又は特異性の決定方法

Also Published As

Publication number Publication date
JPH09507300A (ja) 1997-07-22
ES2284743T3 (es) 2007-11-16
CA2178096A1 (en) 1995-07-13
DK1235072T3 (da) 2007-07-16
DE69535463D1 (de) 2007-05-24
ATE359509T1 (de) 2007-05-15
EP0738390B1 (de) 2003-04-02
ATE236401T1 (de) 2003-04-15
DK0738390T3 (da) 2003-07-21
AU1522195A (en) 1995-08-01
AU700497B2 (en) 1999-01-07
DE69530179T2 (de) 2004-04-08
CA2178096C (en) 2004-03-09
DE69535463T2 (de) 2008-01-03
ES2196056T3 (es) 2003-12-16
US5741653A (en) 1998-04-21
PT738390E (pt) 2003-07-31
EP0738390A1 (de) 1996-10-23
WO1995018969A1 (en) 1995-07-13

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: TELIK, INC., PALO ALTO, CALIF., US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee