DE69535463D1 - Ersatz für Zielobjekte und verbesserten Referenzplatten - Google Patents
Ersatz für Zielobjekte und verbesserten ReferenzplattenInfo
- Publication number
- DE69535463D1 DE69535463D1 DE69535463T DE69535463T DE69535463D1 DE 69535463 D1 DE69535463 D1 DE 69535463D1 DE 69535463 T DE69535463 T DE 69535463T DE 69535463 T DE69535463 T DE 69535463T DE 69535463 D1 DE69535463 D1 DE 69535463D1
- Authority
- DE
- Germany
- Prior art keywords
- reactivity
- receptor
- panel
- panels
- members
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Laminated Bodies (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Forklifts And Lifting Vehicles (AREA)
- Control Of Driving Devices And Active Controlling Of Vehicle (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US177673 | 1980-08-13 | ||
US08/177,673 US5587293A (en) | 1994-01-06 | 1994-01-06 | Method to identify binding partners |
US308813 | 1994-09-19 | ||
US08/308,813 US5798275A (en) | 1994-01-06 | 1994-09-19 | Profiling reference panel enriched by non-IG proteins |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69535463D1 true DE69535463D1 (de) | 2007-05-24 |
DE69535463T2 DE69535463T2 (de) | 2008-01-03 |
Family
ID=26873529
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69530179T Expired - Fee Related DE69530179T2 (de) | 1994-01-06 | 1995-01-05 | Surrogate für bindemoleküle und verbesserte referenzpanele |
DE69535463T Expired - Fee Related DE69535463T2 (de) | 1994-01-06 | 1995-01-05 | Ersatz für Zielobjekte und verbesserte Referenzplatten |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69530179T Expired - Fee Related DE69530179T2 (de) | 1994-01-06 | 1995-01-05 | Surrogate für bindemoleküle und verbesserte referenzpanele |
Country Status (11)
Country | Link |
---|---|
US (1) | US5741653A (de) |
EP (1) | EP0738390B1 (de) |
JP (1) | JPH09507300A (de) |
AT (2) | ATE359509T1 (de) |
AU (1) | AU700497B2 (de) |
CA (1) | CA2178096C (de) |
DE (2) | DE69530179T2 (de) |
DK (2) | DK0738390T3 (de) |
ES (2) | ES2284743T3 (de) |
PT (1) | PT738390E (de) |
WO (1) | WO1995018969A1 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE244300T1 (de) | 1996-01-17 | 2003-07-15 | Imp College Innovations Ltd | Immunotherapie mit verwendung von zytotoxischen t lymphozyten (ctl) |
US6054286A (en) * | 1996-06-18 | 2000-04-25 | Telik, Inc. | Methods to identify immunomodulators using cognate interaction of PKC-theta |
AU5902098A (en) * | 1997-01-03 | 1998-07-31 | Terrapin Technologies, Inc. | Method to classify gene products |
CA2238283C (en) * | 1997-05-30 | 2002-08-20 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of neoplastic lesions, pharmaceutical compositions from such compounds and uses of such compounds and compositions for treating neoplastic lesions |
US5858694A (en) * | 1997-05-30 | 1999-01-12 | Cell Pathways, Inc. | Method for identifying compounds for inhibition of cancerous lesions |
US20010003648A1 (en) | 1997-11-12 | 2001-06-14 | Michael W. Pantoliano | High throughput method for functionally classifying proteins identified using a genomics approach |
CN1285001A (zh) * | 1997-12-18 | 2001-02-21 | 塞普拉科有限公司 | 同时鉴定新型生物靶和用于药物开发的引导结构的方法 |
US6410584B1 (en) | 1998-01-14 | 2002-06-25 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells with indole derivatives |
AU5337599A (en) * | 1998-08-05 | 2000-02-28 | University Of Pittsburgh | Modelling organic compound reactivity in cytochrome p450 mediated reactions |
US6625547B1 (en) | 1998-08-05 | 2003-09-23 | Washington State University Research Foundation | Relative rates of cytochrome p450 metabolism |
ATE343132T1 (de) * | 1998-08-12 | 2006-11-15 | Zycos Inc | Darstellung des profils und katalogisierung von exprimierten proteinmarkern |
US20040224338A1 (en) * | 1998-08-12 | 2004-11-11 | Zycos Inc., A Delaware Corporation | Profiling and cataloging expressed protein tags |
US6200771B1 (en) | 1998-10-15 | 2001-03-13 | Cell Pathways, Inc. | Method of using a novel phosphodiesterase in pharmaceutical screeing to identify compounds for treatment of neoplasia |
US6569631B1 (en) | 1998-11-12 | 2003-05-27 | 3-Dimensional Pharmaceuticals, Inc. | Microplate thermal shift assay for ligand development using 5-(4″dimethylaminophenyl)-2-(4′-phenyl)oxazole derivative fluorescent dyes |
US6133271A (en) * | 1998-11-19 | 2000-10-17 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells and related conditions by exposure thienopyrimidine derivatives |
US6187779B1 (en) | 1998-11-20 | 2001-02-13 | Cell Pathways, Inc. | Method for inhibiting neoplastic cells and related conditions by exposure to 2,8-disubstituted quinazoline derivatives |
US6369092B1 (en) | 1998-11-23 | 2002-04-09 | Cell Pathways, Inc. | Method for treating neoplasia by exposure to substituted benzimidazole derivatives |
US6486155B1 (en) | 1998-11-24 | 2002-11-26 | Cell Pathways Inc | Method of inhibiting neoplastic cells with isoquinoline derivatives |
US6077842A (en) * | 1998-11-24 | 2000-06-20 | Cell Pathways, Inc. | Method of inhibiting neoplastic cells with pyrazolopyridylpyridazinone derivatives |
US6034099A (en) * | 1998-11-24 | 2000-03-07 | Cell Pathways, Inc. | Method for inhibiting neoplastic lesions by administering 4-(arylmethylene)- 2, 3- dihydro-pyrazol-3-ones |
US6875575B1 (en) | 1998-11-25 | 2005-04-05 | Osi Pharmaceuticals, Inc. | Diagnostic methods for neoplasia |
US6025394A (en) | 1999-01-29 | 2000-02-15 | Cell Pathways, Inc. | Method for treating patients with acne by administering substituted sulfonyl indenyl acetic acids, amides and alcohols |
US6020379A (en) * | 1999-02-19 | 2000-02-01 | Cell Pathways, Inc. | Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia |
EP3712897A1 (de) * | 2019-03-22 | 2020-09-23 | Tata Consultancy Services Limited | Automatisierte vorhersage der biologischen reaktion von chemischen verbindungen auf der basis chemischer informationen |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE81146B1 (en) * | 1987-10-13 | 2000-05-03 | Terrapin Tech Inc | Method to produce immunodiagnostic reagents |
US5300425A (en) * | 1987-10-13 | 1994-04-05 | Terrapin Technologies, Inc. | Method to produce immunodiagnostic reagents |
US5338659A (en) * | 1991-04-02 | 1994-08-16 | Terrapin Technologies, Inc. | Method for determining analyte concentration by cross-reactivity profiling |
US5217869A (en) * | 1987-10-13 | 1993-06-08 | Terrapin Technologies, Inc. | Method to produce immunodiagnostic reagents |
US5133866A (en) * | 1988-03-24 | 1992-07-28 | Terrapin Technologies, Inc. | Method to identify analyte-bending ligands |
US4963263A (en) * | 1988-03-24 | 1990-10-16 | Terrapin Technologies, Inc. | Method of identity analyte-binding peptides |
US5340474A (en) * | 1988-03-24 | 1994-08-23 | Terrapin Technologies, Inc. | Panels of analyte-binding ligands |
WO1991010140A2 (en) * | 1989-12-29 | 1991-07-11 | University Technologies International Inc. | Methods for modelling tertiary structures of biologically active ligands including agonists and antagonists thereto and novel synthetic antagonists based on angiotensin |
JPH06502723A (ja) * | 1990-11-09 | 1994-03-24 | ヴェリジェン,インコーポレーテッド | 抗体を検出する分析系の感度及び/又は特異性の決定方法 |
-
1995
- 1995-01-05 WO PCT/US1995/000081 patent/WO1995018969A1/en active IP Right Grant
- 1995-01-05 AU AU15221/95A patent/AU700497B2/en not_active Ceased
- 1995-01-05 AT AT02009879T patent/ATE359509T1/de not_active IP Right Cessation
- 1995-01-05 CA CA002178096A patent/CA2178096C/en not_active Expired - Fee Related
- 1995-01-05 DK DK95906754T patent/DK0738390T3/da active
- 1995-01-05 ES ES02009879T patent/ES2284743T3/es not_active Expired - Lifetime
- 1995-01-05 DE DE69530179T patent/DE69530179T2/de not_active Expired - Fee Related
- 1995-01-05 DE DE69535463T patent/DE69535463T2/de not_active Expired - Fee Related
- 1995-01-05 DK DK02009879T patent/DK1235072T3/da active
- 1995-01-05 JP JP7518574A patent/JPH09507300A/ja active Pending
- 1995-01-05 PT PT95906754T patent/PT738390E/pt unknown
- 1995-01-05 ES ES95906754T patent/ES2196056T3/es not_active Expired - Lifetime
- 1995-01-05 AT AT95906754T patent/ATE236401T1/de not_active IP Right Cessation
- 1995-01-05 EP EP95906754A patent/EP0738390B1/de not_active Expired - Lifetime
-
1996
- 1996-03-26 US US08/622,693 patent/US5741653A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JPH09507300A (ja) | 1997-07-22 |
ES2284743T3 (es) | 2007-11-16 |
CA2178096A1 (en) | 1995-07-13 |
DK1235072T3 (da) | 2007-07-16 |
ATE359509T1 (de) | 2007-05-15 |
EP0738390B1 (de) | 2003-04-02 |
DE69530179D1 (de) | 2003-05-08 |
ATE236401T1 (de) | 2003-04-15 |
DK0738390T3 (da) | 2003-07-21 |
AU1522195A (en) | 1995-08-01 |
AU700497B2 (en) | 1999-01-07 |
DE69530179T2 (de) | 2004-04-08 |
CA2178096C (en) | 2004-03-09 |
DE69535463T2 (de) | 2008-01-03 |
ES2196056T3 (es) | 2003-12-16 |
US5741653A (en) | 1998-04-21 |
PT738390E (pt) | 2003-07-31 |
EP0738390A1 (de) | 1996-10-23 |
WO1995018969A1 (en) | 1995-07-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |