ATE235889T1 - Mikropartikel aus chitosan-gelatin a - Google Patents
Mikropartikel aus chitosan-gelatin aInfo
- Publication number
- ATE235889T1 ATE235889T1 AT98900600T AT98900600T ATE235889T1 AT E235889 T1 ATE235889 T1 AT E235889T1 AT 98900600 T AT98900600 T AT 98900600T AT 98900600 T AT98900600 T AT 98900600T AT E235889 T1 ATE235889 T1 AT E235889T1
- Authority
- AT
- Austria
- Prior art keywords
- bioadhesive
- chitosan
- microspheres
- gelatin microparticles
- chitosan gelatin
- Prior art date
Links
- 229920001661 Chitosan Polymers 0.000 title abstract 3
- 108010010803 Gelatin Proteins 0.000 title abstract 2
- 229920000159 gelatin Polymers 0.000 title abstract 2
- 239000008273 gelatin Substances 0.000 title abstract 2
- 235000019322 gelatine Nutrition 0.000 title abstract 2
- 235000011852 gelatine desserts Nutrition 0.000 title abstract 2
- 239000011859 microparticle Substances 0.000 title 1
- 239000000463 material Substances 0.000 abstract 4
- 239000000227 bioadhesive Substances 0.000 abstract 3
- 239000004005 microsphere Substances 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 abstract 1
- 229920002148 Gellan gum Polymers 0.000 abstract 1
- 102000015271 Intercellular Adhesion Molecule-1 Human genes 0.000 abstract 1
- 108010064593 Intercellular Adhesion Molecule-1 Proteins 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- 229940072056 alginate Drugs 0.000 abstract 1
- 235000010443 alginic acid Nutrition 0.000 abstract 1
- 229920000615 alginic acid Polymers 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 235000010492 gellan gum Nutrition 0.000 abstract 1
- 239000000216 gellan gum Substances 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
- 239000012669 liquid formulation Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9700624.1A GB9700624D0 (en) | 1997-01-14 | 1997-01-14 | Drug delivery composition |
| PCT/GB1998/000108 WO1998030207A1 (en) | 1997-01-14 | 1998-01-14 | Chitosan-gelatin a microparticles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE235889T1 true ATE235889T1 (de) | 2003-04-15 |
Family
ID=10805925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98900600T ATE235889T1 (de) | 1997-01-14 | 1998-01-14 | Mikropartikel aus chitosan-gelatin a |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6465626B1 (OSRAM) |
| EP (1) | EP0952822B1 (OSRAM) |
| JP (1) | JP2001508061A (OSRAM) |
| AT (1) | ATE235889T1 (OSRAM) |
| AU (1) | AU725460B2 (OSRAM) |
| CA (1) | CA2275717C (OSRAM) |
| DE (1) | DE69812887T2 (OSRAM) |
| DK (1) | DK0952822T3 (OSRAM) |
| ES (1) | ES2200306T3 (OSRAM) |
| GB (2) | GB9700624D0 (OSRAM) |
| NO (1) | NO993195D0 (OSRAM) |
| NZ (1) | NZ335815A (OSRAM) |
| PT (1) | PT952822E (OSRAM) |
| WO (1) | WO1998030207A1 (OSRAM) |
| ZA (1) | ZA98273B (OSRAM) |
Families Citing this family (87)
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| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6433040B1 (en) | 1997-09-29 | 2002-08-13 | Inhale Therapeutic Systems, Inc. | Stabilized bioactive preparations and methods of use |
| US6946117B1 (en) | 1997-09-29 | 2005-09-20 | Nektar Therapeutics | Stabilized preparations for use in nebulizers |
| AU3024399A (en) * | 1998-04-03 | 1999-10-25 | Bm Research A/S | Controlled release composition |
| US7022683B1 (en) | 1998-05-13 | 2006-04-04 | Carrington Laboratories, Inc. | Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation |
| WO2000004876A2 (en) * | 1998-07-23 | 2000-02-03 | Johns Hopkins University School Of Medicine | Controlled release of bioactive substances |
| US6916490B1 (en) | 1998-07-23 | 2005-07-12 | UAB Research Center | Controlled release of bioactive substances |
| ES2213948T3 (es) * | 1999-07-02 | 2004-09-01 | Cognis Iberia, S.L. | Microcapsulas ii. |
| GB9924797D0 (en) * | 1999-10-20 | 1999-12-22 | West Pharm Serv Drug Res Ltd | Compound |
| US20030206958A1 (en) * | 2000-12-22 | 2003-11-06 | Cattaneo Maurizio V. | Chitosan biopolymer for the topical delivery of active agents |
| GB0008411D0 (en) * | 2000-04-05 | 2000-05-24 | Vectura Ltd | Pharmaceutical preparations and their manufacture |
| US7442388B2 (en) | 2000-05-10 | 2008-10-28 | Weers Jeffry G | Phospholipid-based powders for drug delivery |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| CA2413251C (en) * | 2000-06-21 | 2012-06-12 | Cubist Pharmaceuticals, Inc. | Compositions and methods to improve the oral absorption of antimicrobial agents |
| US7527807B2 (en) * | 2000-06-21 | 2009-05-05 | Cubist Pharmaceuticals, Inc. | Compositions and methods for increasing the oral absorption of antimicrobials |
| IT1318618B1 (it) * | 2000-07-10 | 2003-08-27 | A C R Applied Coating Res S A | Microsfere bioadesive a rilascio rapido per la somministrazionesublinguale di principi attivi. |
| ITMI20010347A1 (it) | 2001-02-21 | 2002-08-21 | Grisotech S A | Complessi di immunoglobuline e polisaccaridi per assorbimento orale etrans-mucosale |
| US7494669B2 (en) | 2001-02-28 | 2009-02-24 | Carrington Laboratories, Inc. | Delivery of physiological agents with in-situ gels comprising anionic polysaccharides |
| US6777000B2 (en) | 2001-02-28 | 2004-08-17 | Carrington Laboratories, Inc. | In-situ gel formation of pectin |
| CN1543338B (zh) | 2001-08-16 | 2010-06-16 | Cmp医疗有限公司 | 壳多糖微粒及其医疗用途 |
| EP1443944A1 (de) * | 2001-11-12 | 2004-08-11 | Johannes Reinmüller | Pharmazeutische anwendungen von hyaluronsäure-präparaten |
| US7368102B2 (en) | 2001-12-19 | 2008-05-06 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
| US6830556B2 (en) | 2002-01-08 | 2004-12-14 | Zimmer Orthopaedic Surgical Products, Inc. | Debridement extension providing irrigation and mechanical scrubbing for removal of dead, devitalized, or contaminated tissue from a wound |
| AU2003207508A1 (en) * | 2002-01-10 | 2003-07-30 | Northeastern University | Hybrid immobilized catalytic system with controlled permeability |
| US7638138B2 (en) | 2003-02-21 | 2009-12-29 | Translational Research, Ltd. | Compositions for nasal administration of pharmaceuticals |
| WO2004087243A1 (ja) | 2003-03-27 | 2004-10-14 | Bioactis Limited | 鼻腔用粉末薬剤施薬装置 |
| US8383158B2 (en) | 2003-04-15 | 2013-02-26 | Abbott Cardiovascular Systems Inc. | Methods and compositions to treat myocardial conditions |
| AU2004235744A1 (en) * | 2003-05-01 | 2004-11-18 | Archimedes Development Limited | Nasal administration of the LH-RH analog leuprolide |
| CN100381110C (zh) * | 2003-06-16 | 2008-04-16 | 洛马林达大学医学中心 | 可展开的止血剂 |
| US20050118238A1 (en) * | 2003-06-16 | 2005-06-02 | Zhu Yong H. | Deployable hemostatic agent |
| AU2004253463B2 (en) * | 2003-06-16 | 2010-12-09 | Loma Linda University Medical Center | Deployable multifunctional hemostatic agent |
| GB0315632D0 (en) * | 2003-07-04 | 2003-08-13 | West Pharm Serv Drug Res Ltd | Pharmaceutical formulations |
| DE10332160A1 (de) * | 2003-07-15 | 2005-02-03 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Peptid- oder Protein-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
| GB0328186D0 (en) | 2003-12-05 | 2004-01-07 | West Pharm Serv Drug Res Ltd | Intranasal compositions |
| GB0329918D0 (en) | 2003-12-24 | 2004-01-28 | West Pharm Serv Drug Res Ltd | Intranasal compositions |
| US20050175679A1 (en) * | 2004-02-10 | 2005-08-11 | Michael Moshman | Controlled release formulations |
| JP4694214B2 (ja) * | 2004-02-20 | 2011-06-08 | ローム株式会社 | 比較器、ad変換回路、半導体装置、および撮像装置 |
| ES2384519T3 (es) | 2004-02-23 | 2012-07-06 | Loma Linda University Medical Center | Agente hemostático para uso tópico e interno |
| AU2004318688A1 (en) * | 2004-03-23 | 2005-11-03 | Lytone Enterprise, Inc. | Chitosan embedded or encapsulated capsule |
| US7740883B2 (en) * | 2004-03-28 | 2010-06-22 | University Of Debrecen | Nanoparticles from chitosan |
| EP1742612A2 (en) * | 2004-05-06 | 2007-01-17 | Ivrea Pharmaceuticals, Inc. | Particles for the delivery of active agents |
| WO2005112569A2 (en) * | 2004-05-13 | 2005-12-01 | Medtronic Vascular, Inc. | Methods for compounding and delivering a therapeutic agent to the adventitia of a vessel |
| GB0416328D0 (en) * | 2004-07-21 | 2004-08-25 | Univ Cardiff | Use of dry powder compositions for pulmonary delivery |
| WO2006016530A1 (ja) | 2004-08-10 | 2006-02-16 | Translational Research, Ltd. | 速効性でかつ高い吸収性を可能とする経鼻投与用組成物 |
| DE102004059792A1 (de) * | 2004-12-10 | 2006-06-14 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
| WO2006064331A1 (en) * | 2004-12-17 | 2006-06-22 | Medipol Sa | Hydrophilic particles based on cationic chitosan derivatives |
| US20090136505A1 (en) | 2005-02-23 | 2009-05-28 | Johanna Bentz | Intranasal Administration of Active Agents to the Central Nervous System |
| US9539410B2 (en) | 2005-04-19 | 2017-01-10 | Abbott Cardiovascular Systems Inc. | Methods and compositions for treating post-cardial infarction damage |
| US20080125745A1 (en) | 2005-04-19 | 2008-05-29 | Shubhayu Basu | Methods and compositions for treating post-cardial infarction damage |
| US8303972B2 (en) * | 2005-04-19 | 2012-11-06 | Advanced Cardiovascular Systems, Inc. | Hydrogel bioscaffoldings and biomedical device coatings |
| CA2606386C (en) * | 2005-04-29 | 2014-06-10 | Cubist Pharmaceuticals, Inc. | Therapeutic compositions |
| JP2007006849A (ja) * | 2005-07-04 | 2007-01-18 | Japan Science & Technology Agency | 6−アミノ−6−デオキシキトサン誘導体から成る核酸導入剤 |
| AU2007285472B2 (en) * | 2006-03-30 | 2013-10-24 | Engene, Inc. | Non-viral compositions and methods for transfecting gut cells in vivo |
| CA2848648C (en) * | 2006-06-02 | 2017-10-10 | Synedgen, Inc. | Chitosan-derivative compounds and methods of controlling microbial populations |
| WO2007148048A1 (en) | 2006-06-20 | 2007-12-27 | Cmp Therapeutics Limited | Compositions comprising chitin microparticles and their medical uses |
| US20080248508A1 (en) * | 2006-08-17 | 2008-10-09 | Shenda Baker | Methods of making a chitosan product having an ultra-low endotoxin concentration and the ultra-low endotoxin chitosan product derived therefrom and method of accurately determining inflammatory and anti-inflammatory cellular response to such materials |
| US9242005B1 (en) | 2006-08-21 | 2016-01-26 | Abbott Cardiovascular Systems Inc. | Pro-healing agent formulation compositions, methods and treatments |
| US9005672B2 (en) | 2006-11-17 | 2015-04-14 | Abbott Cardiovascular Systems Inc. | Methods of modifying myocardial infarction expansion |
| US8741326B2 (en) * | 2006-11-17 | 2014-06-03 | Abbott Cardiovascular Systems Inc. | Modified two-component gelation systems, methods of use and methods of manufacture |
| ES2652415T3 (es) | 2006-12-26 | 2018-02-02 | Shin Nippon Biomedical Laboratories, Ltd. | Preparación para aplicación transnasal |
| WO2008091588A1 (en) | 2007-01-22 | 2008-07-31 | Targacept, Inc. | Intranasal, buccal, and sublingual administration of metanicotine analogs |
| GB0716907D0 (en) | 2007-08-31 | 2007-10-10 | Archimedes Dev Ltd | Pharmaceutical powder compositions |
| GB0722507D0 (en) * | 2007-11-19 | 2007-12-27 | Zhao Xiaobin | Hyaluronic acid personal lubricant |
| DE102008059857A1 (de) * | 2008-12-01 | 2010-06-02 | Forschungsinstitut für Leder und Kunststoffbahnen gGmbH | Mit Kohlenhydrat-Derivaten additivierte Gelatinezusammensetzungen |
| EP2429495A4 (en) | 2009-05-15 | 2014-01-22 | Shin Nippon Biomedical Lab Ltd | INTRANASAL PHARMACEUTICAL COMPOSITION WITH IMPROVED PHARMACOKINETICS |
| GB2472327B (en) | 2009-07-31 | 2013-03-13 | Shin Nippon Biomedical Lab Ltd | Intranasal granisetron and nasal applicator |
| WO2011066471A1 (en) | 2009-11-25 | 2011-06-03 | Loma Linda University Medical Center | Chitosan-based hemostatic textile |
| GB201006218D0 (en) | 2010-04-14 | 2010-06-02 | Ayanda As | Composition |
| CA3023121A1 (en) * | 2011-04-11 | 2012-10-18 | Vitux Group As | Oral pharmaceutical dispersion compositions |
| US8968790B2 (en) * | 2011-12-09 | 2015-03-03 | Shaker A. Mousa | Nanoformulation of vitamin D derivatives and/or vitamin D metabolites |
| FR2991172A1 (fr) * | 2012-06-01 | 2013-12-06 | Galderma Res & Dev | Compositions pharmaceutiques topiques comprenant des microcapsules |
| EP2863892B1 (en) | 2012-06-20 | 2017-11-08 | University Of Waterloo | Mucoadhesive nanoparticle delivery system |
| US9878000B2 (en) | 2012-06-20 | 2018-01-30 | University Of Waterloo | Mucoadhesive nanoparticle composition comprising immunosuppresant and methods of use thereof |
| US9259357B2 (en) | 2014-04-16 | 2016-02-16 | Loma Linda University | Composition, preparation, and use of chitosan shards for biomedical applications |
| US10182993B2 (en) | 2015-04-06 | 2019-01-22 | Patheon Softgels Inc. | Compositions for colonic delivery of drugs |
| US12427224B1 (en) * | 2015-10-15 | 2025-09-30 | Oceanit Laboratories, Inc. | Hemostatic microparticles and dressing |
| SG10202107367SA (en) | 2016-12-31 | 2021-08-30 | Bioxcel Therapeutics Inc | Use of sublingual dexmedetomidine for the treatment of agitation |
| US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
| US12343472B2 (en) | 2018-02-26 | 2025-07-01 | Shin Nippon Biomedical Laboratories, Ltd. | Powder preparation, cartridge, and device |
| ES3004544T3 (en) | 2018-06-27 | 2025-03-12 | Bioxcel Therapeutics Inc | Film formulations containing dexmedetomidine and methods of producing them |
| NL2022788B1 (en) * | 2019-03-22 | 2020-09-28 | No Ceuticals B V | Chitosan nitrate for use as a nitric oxide donor (NO donor) |
| US20240024288A1 (en) | 2019-07-19 | 2024-01-25 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| CN112370437B (zh) * | 2020-10-20 | 2022-10-21 | 好医生药业集团有限公司 | 一种阿莫西林胶囊及其制备方法 |
| US11806334B1 (en) | 2023-01-12 | 2023-11-07 | Bioxcel Therapeutics, Inc. | Non-sedating dexmedetomidine treatment regimens |
| CN118304423B (zh) * | 2023-05-25 | 2024-10-11 | 无锡市第二人民医院 | 多层级壳聚糖明胶颗粒载P4HA1 siRNA通过抑制细胞EMT治疗脑胶质瘤的研究 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4226849A (en) | 1979-06-14 | 1980-10-07 | Forest Laboratories Inc. | Sustained release therapeutic compositions |
| JPS6034925B2 (ja) | 1979-07-31 | 1985-08-12 | 帝人株式会社 | 持続性鼻腔用製剤およびその製造法 |
| CA1219201A (en) | 1983-03-07 | 1987-03-17 | Albert E. Chu | Microorganism detection test |
| GB8712176D0 (en) | 1987-05-22 | 1987-06-24 | Cosmas Damian Ltd | Drug delivery system |
| GB8723846D0 (en) | 1987-10-10 | 1987-11-11 | Danbiosyst Ltd | Bioadhesive microsphere drug delivery system |
| CA2004270A1 (en) * | 1988-12-29 | 1990-06-29 | William R. Michael | Perfume microcapsules for use in granular detergent compositions |
| GB8904370D0 (en) | 1989-02-25 | 1989-04-12 | Cosmas Damian Ltd | Liquid delivery compositions |
| BE1003677A3 (nl) | 1990-01-29 | 1992-05-19 | Schacht Etienne | Werkwijze voor het bereiden van azobevattende polymeren en het gebruik ervan als geneesmiddelafgiftesystemen. |
| EP0454444A1 (en) | 1990-04-24 | 1991-10-30 | Nissan Chemical Industries Ltd. | Glutarimide derivatives and herbicides |
| CA2042529C (en) | 1990-08-10 | 2002-07-30 | Chokyun Rha | Polysaccharide article and uses therefor |
| IT1243390B (it) | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
| GB9414966D0 (en) * | 1994-07-26 | 1994-09-14 | Danbiosyst Uk | Pharmaceutical compositions for the nasal administration of antiviral agents |
| GB9416884D0 (en) | 1994-08-20 | 1994-10-12 | Danbiosyst Uk | Drug delivery compositions |
| GB9419979D0 (en) | 1994-10-04 | 1994-11-16 | Medeva Holdings Bv | Vaccine compositions |
| GB9516268D0 (en) | 1995-08-08 | 1995-10-11 | Danbiosyst Uk | Compositiion for enhanced uptake of polar drugs from the colon |
-
1997
- 1997-01-14 GB GBGB9700624.1A patent/GB9700624D0/en active Pending
-
1998
- 1998-01-13 ZA ZA9800273A patent/ZA98273B/xx unknown
- 1998-01-14 US US09/341,546 patent/US6465626B1/en not_active Expired - Lifetime
- 1998-01-14 GB GB9916018A patent/GB2335357B/en not_active Expired - Fee Related
- 1998-01-14 EP EP98900600A patent/EP0952822B1/en not_active Expired - Lifetime
- 1998-01-14 DK DK98900600T patent/DK0952822T3/da active
- 1998-01-14 PT PT98900600T patent/PT952822E/pt unknown
- 1998-01-14 WO PCT/GB1998/000108 patent/WO1998030207A1/en not_active Ceased
- 1998-01-14 DE DE69812887T patent/DE69812887T2/de not_active Expired - Lifetime
- 1998-01-14 JP JP53067598A patent/JP2001508061A/ja not_active Ceased
- 1998-01-14 AU AU55689/98A patent/AU725460B2/en not_active Ceased
- 1998-01-14 AT AT98900600T patent/ATE235889T1/de active
- 1998-01-14 NZ NZ335815A patent/NZ335815A/en not_active IP Right Cessation
- 1998-01-14 ES ES98900600T patent/ES2200306T3/es not_active Expired - Lifetime
- 1998-01-14 CA CA002275717A patent/CA2275717C/en not_active Expired - Fee Related
-
1999
- 1999-06-28 NO NO993195A patent/NO993195D0/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2001508061A (ja) | 2001-06-19 |
| GB2335357B (en) | 2000-12-13 |
| EP0952822A1 (en) | 1999-11-03 |
| WO1998030207A1 (en) | 1998-07-16 |
| ZA98273B (en) | 1999-07-13 |
| GB9700624D0 (en) | 1997-03-05 |
| NO993195L (no) | 1999-06-28 |
| ES2200306T3 (es) | 2004-03-01 |
| AU5568998A (en) | 1998-08-03 |
| PT952822E (pt) | 2003-08-29 |
| DE69812887D1 (de) | 2003-05-08 |
| AU725460B2 (en) | 2000-10-12 |
| CA2275717A1 (en) | 1998-07-16 |
| NZ335815A (en) | 2001-03-30 |
| US6465626B1 (en) | 2002-10-15 |
| DE69812887T2 (de) | 2003-12-18 |
| EP0952822B1 (en) | 2003-04-02 |
| CA2275717C (en) | 2007-09-11 |
| GB2335357A (en) | 1999-09-22 |
| GB9916018D0 (en) | 1999-09-08 |
| NO993195D0 (no) | 1999-06-28 |
| DK0952822T3 (da) | 2003-07-21 |
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