ATE232109T1 - Synthetische, vielfache tandemwiederholungen des mucinpeptides und seiner derivate und deren verwendung - Google Patents
Synthetische, vielfache tandemwiederholungen des mucinpeptides und seiner derivate und deren verwendungInfo
- Publication number
- ATE232109T1 ATE232109T1 AT94925121T AT94925121T ATE232109T1 AT E232109 T1 ATE232109 T1 AT E232109T1 AT 94925121 T AT94925121 T AT 94925121T AT 94925121 T AT94925121 T AT 94925121T AT E232109 T1 ATE232109 T1 AT E232109T1
- Authority
- AT
- Austria
- Prior art keywords
- muc
- tandem repeats
- derivatives
- peptides
- multiple tandem
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 101100346932 Mus musculus Muc1 gene Proteins 0.000 abstract 3
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000013595 glycosylation Effects 0.000 abstract 1
- 238000006206 glycosylation reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4727—Mucins, e.g. human intestinal mucin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
- F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
- F02B75/00—Other engines
- F02B75/02—Engines characterised by their cycles, e.g. six-stroke
- F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
- F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/099,354 US5744144A (en) | 1993-07-30 | 1993-07-30 | Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof |
| PCT/US1994/008477 WO1995003825A1 (en) | 1993-07-30 | 1994-07-29 | Synthetic multiple tandem repeat mucin and mucin-like peptides, and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE232109T1 true ATE232109T1 (de) | 2003-02-15 |
Family
ID=22274597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94925121T ATE232109T1 (de) | 1993-07-30 | 1994-07-29 | Synthetische, vielfache tandemwiederholungen des mucinpeptides und seiner derivate und deren verwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US5744144A (de) |
| EP (1) | EP0804231B1 (de) |
| JP (1) | JPH09501159A (de) |
| AT (1) | ATE232109T1 (de) |
| CA (1) | CA2167730A1 (de) |
| DE (1) | DE69432109T2 (de) |
| WO (1) | WO1995003825A1 (de) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPN568095A0 (en) * | 1995-09-27 | 1995-10-26 | Austin Research Institute, The | Anti-Galalpha(1,3)Gal antibody binding peptides |
| AU703120B2 (en) | 1995-10-20 | 1999-03-18 | University Of Nebraska Board Of Regents | Composition and methods for enhancing immune responses mediated by antigen-presenting cells |
| US20080286228A1 (en) * | 1995-10-20 | 2008-11-20 | Tarantolo Stefano R | Compositions and methods for enhancing immune responses mediated by antigen-presenting cells |
| AU2116497A (en) * | 1996-01-31 | 1997-08-22 | Population Council, The | Multivalent chimeric peptides as microbicides |
| AU734253B2 (en) * | 1996-03-20 | 2001-06-07 | Sloan-Kettering Institute For Cancer Research | Conjugated mucin peptide vaccines |
| AU2540897A (en) * | 1996-03-21 | 1997-10-10 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Methods and compositions of chimeric polypeptides for tumor antigen vaccines |
| JP3945822B2 (ja) * | 1996-05-24 | 2007-07-18 | カイロン コーポレイション | 複数エピトープ融合タンパク質 |
| US6514731B1 (en) | 1996-05-24 | 2003-02-04 | Chiron Corporation | Methods for the preparation of hepatitis C virus multiple copy epitope fusion antigens |
| AU741258B2 (en) * | 1996-09-10 | 2001-11-29 | Biomira Inc. | MUC-1 as an immunosuppressive therapeutic agent for the treatment of inflammatory and autoimmune conditions |
| WO1998017300A1 (en) * | 1996-10-25 | 1998-04-30 | Dana-Farber Cancer Institute, Inc. | Mucin-mediated immunomodulation |
| EP1012276A2 (de) * | 1997-02-24 | 2000-06-28 | Therion Biologics Corporation | Rekombinantes poxvirus zur immunisierung gegen muc1 tumor-assoziiertes antigen |
| GB9810040D0 (en) | 1998-05-11 | 1998-07-08 | Univ Nottingham | Blood borne tumour markers |
| AU755017B2 (en) * | 1998-06-26 | 2002-11-28 | Biomira Inc. | Method of detecting T-cell activation |
| DE69941627D1 (de) * | 1998-11-05 | 2009-12-17 | Univ Michigan | Für krebs |
| GB9827228D0 (en) * | 1998-12-10 | 1999-02-03 | Univ Nottingham | Cancer detection method and reagents |
| DE19906615A1 (de) * | 1999-02-17 | 2000-09-28 | Hanisch Franz Georg | Peptid-Varianten des Tumormarkers MUC1 und ihre Verwendung |
| GB9904695D0 (en) * | 1999-03-01 | 1999-04-21 | Imp Cancer Res Tech | Peptide |
| GB9930359D0 (en) * | 1999-12-22 | 2000-02-09 | Glaxo Group Ltd | Novel polypeptides |
| CA2322057A1 (en) * | 2000-05-18 | 2001-11-18 | Dnavec Research Inc. | Paramyxovirus vectors used for transfer of foreign genes |
| US20030232399A1 (en) * | 2000-06-14 | 2003-12-18 | Robertson John Forsyth Russell | Cancer detection methods and reagents |
| DK1889630T3 (da) | 2000-10-18 | 2012-03-05 | Glaxosmithkline Biolog Sa | Vacciner omfattende MAGE-antigen koblet til protein D-fragment |
| WO2002062319A2 (en) * | 2001-01-19 | 2002-08-15 | Corixa Corporation | Microsphere delivery of mucin peptides |
| JP2004533421A (ja) | 2001-03-27 | 2004-11-04 | バイオミラ,インコーポレイテッド | T1免疫応答とt2免疫応答との間で調節するためのワクチン |
| US7183388B2 (en) * | 2001-03-30 | 2007-02-27 | The Regents Of The University Of California | Anti-MUC-1 single chain antibodies for tumor targeting |
| EP1383802A4 (de) * | 2001-03-30 | 2005-08-03 | Univ California | Anti-muc-1-einzelkettenantikörper zum targeting von tumoren |
| GB0109297D0 (en) | 2001-04-12 | 2001-05-30 | Glaxosmithkline Biolog Sa | Vaccine |
| US7247297B2 (en) * | 2001-09-14 | 2007-07-24 | The University Of Chicago | Use of DF3/MUC1 regulated expression in gene therapy |
| AU2002240734A1 (en) * | 2001-10-18 | 2003-04-28 | Zlatko Ademovic | Repetitive motifs from salivary proline rich proteins, mucin and collagen |
| AU2002332697A1 (en) * | 2001-12-12 | 2003-06-23 | Leon J. Lewandowski | Photophoretic auto immune stimulation |
| US7659240B2 (en) * | 2002-01-14 | 2010-02-09 | Vertex Pharmaceuticals Incorporated | Mucin immobilized chromatography |
| AU2003203079B8 (en) * | 2002-02-04 | 2009-01-15 | Oncothyreon Inc. | Immunostimulatory, covalently lipidated oligonucleotides |
| US20060069238A1 (en) * | 2002-04-15 | 2006-03-30 | Biomira, Inc. | Synthetic glyco-lipo-peptides as vaccines |
| CN100360555C (zh) | 2002-04-19 | 2008-01-09 | 多伦多大学董事局 | 治疗阿尔茨海默氏病的免疫学方法及组合物 |
| GB0212036D0 (en) * | 2002-05-24 | 2002-07-03 | Glaxo Group Ltd | Vaccines |
| AU2003258710A1 (en) * | 2002-09-05 | 2004-03-29 | Universitat Zu Koln | Immunogenic muc1 glycopeptides |
| GB2395270B (en) * | 2002-11-14 | 2006-08-16 | Univ Nottingham | Tumour marker proteins and uses thereof |
| US8343502B2 (en) * | 2002-12-16 | 2013-01-01 | Globeimmune, Inc. | Yeast-based vaccines as immunotherapy |
| KR101241272B1 (ko) | 2002-12-16 | 2013-03-15 | 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 | 면역 요법으로서의 효모계 백신 |
| US7696306B2 (en) * | 2003-07-11 | 2010-04-13 | Board of Agents of the University of Nebraska | Compositions and methods for preventing or treating cancer |
| CN1902312B (zh) | 2003-11-04 | 2011-02-23 | 株式会社载体研究所 | 制备导入了基因的树突细胞的方法 |
| WO2005046614A2 (en) * | 2003-11-12 | 2005-05-26 | Therion Biologics Corporation | System for treating and preventing breast cancer |
| US8901093B2 (en) * | 2003-11-12 | 2014-12-02 | The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services | Custom vectors for treating and preventing pancreatic cancer |
| AU2004299457B2 (en) | 2003-12-12 | 2011-03-24 | Government Of The United States Of America, As Represented By The Secretary Department Of Health And Human Services | A human cytotoxic T-lymphocyte epitope and its agonist epitope from the non-variable number of tandem repeat sequence of MUC-1 |
| TW201204410A (en) * | 2004-04-01 | 2012-02-01 | Oncothyreon Inc | Mucinous glycoprotein (MUC-1) vaccine |
| US20100129385A1 (en) * | 2005-02-08 | 2010-05-27 | Jackson David C | Immunogenic molecules |
| GB2426581A (en) * | 2005-05-27 | 2006-11-29 | Univ Nottingham | Immunoassay methods |
| PT1889059E (pt) | 2005-05-27 | 2009-10-01 | Oncimmune Ltd | Métodos de imunoensaio melhorados |
| JP5364371B2 (ja) | 2005-06-28 | 2013-12-11 | オンコセリオン インコーポレイテッド | ムチン糖タンパク質(muc−1)ワクチンによって患者を処置する方法 |
| TWI457133B (zh) | 2005-12-13 | 2014-10-21 | Glaxosmithkline Biolog Sa | 新穎組合物 |
| EP2025762A3 (de) | 2006-01-17 | 2009-09-30 | Health Research Inc. | Heteroduplex-Trackingassay |
| EP1983048A4 (de) | 2006-01-17 | 2009-04-22 | Dnavec Corp | Neues proteinexpressionssystem |
| EP2048232A4 (de) | 2006-07-13 | 2010-10-13 | Dnavec Corp | Nichtreplizierender paramyxoviridae-virusvektor |
| US20090317414A1 (en) * | 2006-07-25 | 2009-12-24 | 4G Vaccines Pty Ltd | Cancer vaccine comprising a mucin 1 (muc1) t cell epitope-derived peptide |
| US8574848B2 (en) | 2006-09-13 | 2013-11-05 | Oncimmune Ltd. | Immunoassay methods |
| WO2008127680A2 (en) * | 2007-04-11 | 2008-10-23 | The Jackson Laboratory | Diagnosis and treatment of diseases caused by misfolded proteins |
| US20090124557A1 (en) * | 2007-04-16 | 2009-05-14 | Yeda Research And Development Co. Ltd. | Compositions and methods for treating cancer |
| KR101238795B1 (ko) | 2007-05-24 | 2013-03-07 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 동결건조 항원 조성물 |
| GB0725239D0 (en) * | 2007-12-24 | 2008-02-06 | Oncimmune Ltd | Calibrator for autoantibody assay |
| WO2010055900A1 (ja) | 2008-11-14 | 2010-05-20 | ディナベック株式会社 | 樹状細胞の製造方法 |
| JP6096111B2 (ja) | 2010-05-10 | 2017-03-15 | アセンド・バイオファーマシューティカルズ・リミテッド | 免疫刺激組成物及びワクチン組成物 |
| CN105193724A (zh) | 2011-02-24 | 2015-12-30 | 肿瘤防护公司 | 含有佐剂的以muc1 为基础的糖脂肽疫苗 |
| WO2013103658A1 (en) | 2012-01-03 | 2013-07-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Native and agonist ctl epitopes of the muc1 tumor antigen |
| WO2016105536A2 (en) * | 2014-12-23 | 2016-06-30 | University Of Maryland, Baltimore | Muc1 decoy peptides for treatment and prevention of bacterial infections |
| EP3518964A2 (de) | 2016-09-28 | 2019-08-07 | Bavarian Nordic A/S | Zusammensetzungen und verfahren zur erhöhung der stabilität von transgenen in pockenviren |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2003211A1 (en) * | 1988-11-17 | 1990-05-17 | Pei-Xiang Xing | Monoclonal antibodies |
| WO1991008217A1 (en) * | 1989-12-05 | 1991-06-13 | The Regents Of The University Of California | Human intestinal mucins |
-
1993
- 1993-07-30 US US08/099,354 patent/US5744144A/en not_active Expired - Lifetime
-
1994
- 1994-07-29 DE DE69432109T patent/DE69432109T2/de not_active Expired - Fee Related
- 1994-07-29 AT AT94925121T patent/ATE232109T1/de not_active IP Right Cessation
- 1994-07-29 JP JP7505945A patent/JPH09501159A/ja active Pending
- 1994-07-29 EP EP94925121A patent/EP0804231B1/de not_active Expired - Lifetime
- 1994-07-29 CA CA002167730A patent/CA2167730A1/en not_active Abandoned
- 1994-07-29 WO PCT/US1994/008477 patent/WO1995003825A1/en not_active Ceased
- 1994-08-10 US US08/288,059 patent/US5827666A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995003825A1 (en) | 1995-02-09 |
| DE69432109T2 (de) | 2003-11-20 |
| EP0804231B1 (de) | 2003-02-05 |
| DE69432109D1 (de) | 2003-03-13 |
| US5827666A (en) | 1998-10-27 |
| CA2167730A1 (en) | 1995-02-09 |
| EP0804231A4 (de) | 1999-08-18 |
| JPH09501159A (ja) | 1997-02-04 |
| US5744144A (en) | 1998-04-28 |
| EP0804231A1 (de) | 1997-11-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |