DE69524971D1 - Neue familie von proteaseinhibitoren und andere biologisch aktive substanzen - Google Patents

Neue familie von proteaseinhibitoren und andere biologisch aktive substanzen

Info

Publication number
DE69524971D1
DE69524971D1 DE69524971T DE69524971T DE69524971D1 DE 69524971 D1 DE69524971 D1 DE 69524971D1 DE 69524971 T DE69524971 T DE 69524971T DE 69524971 T DE69524971 T DE 69524971T DE 69524971 D1 DE69524971 D1 DE 69524971D1
Authority
DE
Germany
Prior art keywords
inhibitors
relates
biologically active
active substances
new family
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69524971T
Other languages
English (en)
Other versions
DE69524971T2 (de
Inventor
Gerard Voerman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vitaleech Bioscience N V
Original Assignee
Vitaleech Bioscience N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vitaleech Bioscience N V filed Critical Vitaleech Bioscience N V
Application granted granted Critical
Publication of DE69524971D1 publication Critical patent/DE69524971D1/de
Publication of DE69524971T2 publication Critical patent/DE69524971T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69524971T 1994-10-28 1995-10-27 Neue familie von proteaseinhibitoren und andere biologisch aktive substanzen Expired - Lifetime DE69524971T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94117053 1994-10-28
EP95103637 1995-03-14
PCT/EP1995/004223 WO1996013585A1 (en) 1994-10-28 1995-10-27 A novel family of protease inhibitors, and other biologic active substances

Publications (2)

Publication Number Publication Date
DE69524971D1 true DE69524971D1 (de) 2002-02-14
DE69524971T2 DE69524971T2 (de) 2002-08-29

Family

ID=26135896

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69524971T Expired - Lifetime DE69524971T2 (de) 1994-10-28 1995-10-27 Neue familie von proteaseinhibitoren und andere biologisch aktive substanzen

Country Status (11)

Country Link
US (1) US6239106B1 (de)
EP (1) EP0789764B1 (de)
JP (1) JP4278175B2 (de)
AT (1) ATE211765T1 (de)
AU (1) AU3870195A (de)
CA (1) CA2203827A1 (de)
DE (1) DE69524971T2 (de)
DK (1) DK0789764T3 (de)
ES (1) ES2171563T3 (de)
PT (1) PT789764E (de)
WO (1) WO1996013585A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2235394A1 (en) 1995-11-13 1997-05-22 Gerard Voerman Anti-viral isolates obtainable from leeches
AUPO427596A0 (en) * 1996-12-20 1997-01-23 Cooperative Research Centre For Tropical Plant Pathology Anti-microbial protein
EP0875564A1 (de) * 1997-05-02 1998-11-04 Gerard Voerman Biologisch aktives Extrakt aus den Blutegeln 'Limnatis nilotica'
FR2763944B1 (fr) * 1997-06-03 2000-12-15 Centre Nat Rech Scient Nouveaux derives de coumarines, leurs procedes de preparation et leur application comme medicaments en tant qu'inhibiteurs de proteases
US6232287B1 (en) * 1998-03-13 2001-05-15 The Burnham Institute Molecules that home to various selected organs or tissues
US6774107B1 (en) * 1999-03-18 2004-08-10 Merck Patent Gmbh Protein for blocking platelet adhesion
CN105592854A (zh) * 2013-08-05 2016-05-18 杰拉德·沃尔曼 使吸烟的不利作用减少的新方法
EP3193910A1 (de) * 2014-08-05 2017-07-26 Réunion Therapeutics B.V. Mutante von blutegelabgeleiteten inhibitoren der neutrophilen elastase und verwendungen davon
CN105646702B (zh) * 2016-04-13 2019-03-01 中国科学院昆明动物研究所 菲牛蛭Kazal型胰蛋白酶抑制剂Bdellin-HM及其编码基因和应用
JP2020531586A (ja) * 2017-08-27 2020-11-05 アンタイ−ヴァイラル テクノロジーズ， エルエルシー 合成リジンアナログ及び模倣物の抗ウイルス用途のための方法及び組成物
US11262125B2 (en) * 2018-01-02 2022-03-01 Praxair Technology, Inc. System and method for flexible recovery of argon from a cryogenic air separation unit
US20240207484A1 (en) * 2021-04-30 2024-06-27 The Regents Of The University Of California Cartilage treatment for use in eyelid reconstruction

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86857A (en) * 1988-06-24 1994-04-12 Yissum Res Dev Co Platelet-aggregating inhibitory agents from leech saliva and pharmaceutical preparations containing the same
US5863534A (en) * 1993-04-09 1999-01-26 Bio-Technology General Corp. Polypeptide having factor Xa inhibitory method of reducing blood coagulation with a novel polypeptide having factor Xa inhibitory activity

Also Published As

Publication number Publication date
DE69524971T2 (de) 2002-08-29
EP0789764A1 (de) 1997-08-20
DK0789764T3 (da) 2002-04-22
PT789764E (pt) 2002-06-28
CA2203827A1 (en) 1996-05-09
ES2171563T3 (es) 2002-09-16
JPH10509589A (ja) 1998-09-22
WO1996013585A1 (en) 1996-05-09
EP0789764B1 (de) 2002-01-09
ATE211765T1 (de) 2002-01-15
JP4278175B2 (ja) 2009-06-10
US6239106B1 (en) 2001-05-29
AU3870195A (en) 1996-05-23

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