ATE227579T1 - Verfahren zur herstellung von makrophagen und ausrüstungen zur durchführung dieses verfahrens - Google Patents

Verfahren zur herstellung von makrophagen und ausrüstungen zur durchführung dieses verfahrens

Info

Publication number
ATE227579T1
ATE227579T1 AT96901848T AT96901848T ATE227579T1 AT E227579 T1 ATE227579 T1 AT E227579T1 AT 96901848 T AT96901848 T AT 96901848T AT 96901848 T AT96901848 T AT 96901848T AT E227579 T1 ATE227579 T1 AT E227579T1
Authority
AT
Austria
Prior art keywords
stage
carrying
equipment
monocytes
constituents
Prior art date
Application number
AT96901848T
Other languages
English (en)
Inventor
Jean-Loup Romet-Lemonne
Mohamed Chokri
Original Assignee
Idm Immuno Designed Molecules
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Idm Immuno Designed Molecules filed Critical Idm Immuno Designed Molecules
Application granted granted Critical
Publication of ATE227579T1 publication Critical patent/ATE227579T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0645—Macrophages, e.g. Kuepfer cells in the liver; Monocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/24—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/25—Tumour necrosing factors [TNF]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT96901848T 1995-01-24 1996-01-24 Verfahren zur herstellung von makrophagen und ausrüstungen zur durchführung dieses verfahrens ATE227579T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9500785A FR2729570A1 (fr) 1995-01-24 1995-01-24 Procede de preparation de macrophages actives, trousses et compositions pour la mise en oeuvre de ce procede
PCT/FR1996/000121 WO1996022781A1 (fr) 1995-01-24 1996-01-24 Procede de preparation de macrophages, trousses et compositions pour la mise en ×uvre de ce procede

Publications (1)

Publication Number Publication Date
ATE227579T1 true ATE227579T1 (de) 2002-11-15

Family

ID=9475438

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96901848T ATE227579T1 (de) 1995-01-24 1996-01-24 Verfahren zur herstellung von makrophagen und ausrüstungen zur durchführung dieses verfahrens

Country Status (10)

Country Link
US (3) US5804442A (de)
EP (1) EP0806959B1 (de)
JP (1) JP3537443B2 (de)
AT (1) ATE227579T1 (de)
AU (1) AU720285B2 (de)
CA (1) CA2210449C (de)
DE (1) DE69624789T2 (de)
ES (1) ES2185759T3 (de)
FR (1) FR2729570A1 (de)
WO (1) WO1996022781A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL110195A (en) * 1994-07-03 2003-10-31 David Danon Method and system for cultivating macrophages
FR2729570A1 (fr) * 1995-01-24 1996-07-26 Idm Immuno Designed Molecules Procede de preparation de macrophages actives, trousses et compositions pour la mise en oeuvre de ce procede
EP0808897A1 (de) * 1996-05-21 1997-11-26 I.D.M. Immuno-Designed Molecules Antigenpräsentierende Zellen, ein Verfahren zur deren Herstellung und deren Verwendung als zelluläre Impfstoffen
US20020068048A1 (en) * 1997-09-05 2002-06-06 Patrick A. Dreyfus Method for the treatment or diagnosis of human pathologies with disseminated or difficult to access cells or tissues
CA2320491A1 (en) 1998-03-30 1999-10-07 I.D.M. Immuno-Designed Molecules Stimulated monocyte derived cells, their preparation and uses
JP2002509717A (ja) * 1998-03-30 2002-04-02 イ・デ・エム・イミュノ−デジネ・モレキュル 抑制された単球由来細胞、それらの調製法及びそれらの医薬組成物における使用
US6616925B1 (en) * 1998-04-02 2003-09-09 I.D.M. Immuno-Designed Molecules Combined preparation for the treatment of neoplasic diseases or of infectious diseases
AU3601299A (en) * 1998-04-09 1999-11-01 I.D.M. Immuno-Designed Molecules Use of monocytes derived cells and antibodies in a synergic way for optimal induction of immunotherapeutic efficiency
US20020168347A1 (en) * 1998-04-09 2002-11-14 Jacques Bartholeyns Use of monocytes derived cells, antigens and antibodies for optimal induction of immunotherapeutic efficiency
AU4251300A (en) 1999-05-07 2000-11-21 University Of Virginia Patent Foundation Biological production of stable glutamine, poly-glutamine derivatives in transgenic organisms and their use for therapeutic purposes
US6867041B2 (en) * 2000-02-24 2005-03-15 Xcyte Therapies, Inc. Simultaneous stimulation and concentration of cells
US20030119185A1 (en) * 2000-02-24 2003-06-26 Xcyte Therapies, Inc. Activation and expansion of cells
US7572631B2 (en) * 2000-02-24 2009-08-11 Invitrogen Corporation Activation and expansion of T cells
US20030235908A1 (en) * 2000-02-24 2003-12-25 Xcyte Therapies, Inc. Activation and expansion of cells
US6797514B2 (en) * 2000-02-24 2004-09-28 Xcyte Therapies, Inc. Simultaneous stimulation and concentration of cells
US7541184B2 (en) 2000-02-24 2009-06-02 Invitrogen Corporation Activation and expansion of cells
JP2003534283A (ja) * 2000-05-25 2003-11-18 エクサイト セラピーズ， インコーポレイテッド 天然で誘導されたかまたは人工的に誘導された免疫抑制後にｔ細胞免疫サーベイランスを回復もしくは増強するための方法
EP1454135B1 (de) * 2001-12-05 2009-01-21 CaridianBCT, Inc. Verfahren und vorrichtung zur trennung von blutbestandteilen
US20040175373A1 (en) * 2002-06-28 2004-09-09 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
US20050084967A1 (en) * 2002-06-28 2005-04-21 Xcyte Therapies, Inc. Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
US20040151704A1 (en) * 2002-06-28 2004-08-05 Xcyte Therapies, Inc. Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
US6914120B2 (en) * 2002-11-13 2005-07-05 Eastman Chemical Company Method for making isosorbide containing polyesters
DK1623017T3 (da) * 2003-05-08 2011-01-10 Life Technologies Corp Frembringelse og isolering af antigenspecifikke T-celler
DE10339762B4 (de) * 2003-08-27 2007-08-02 Infineon Technologies Ag Chipstapel von Halbleiterchips und Verfahren zur Herstellung desselben
EP1663308A1 (de) * 2003-09-22 2006-06-07 Xcyte Therapies, Inc Zusammensetzungen und verfahren zur beschleunigung der hämatologischen erholung
DE10358590A1 (de) * 2003-12-12 2005-07-07 Newfrey Llc, Newark Verfahren zur Vorbehandlung von Oberflächen von Schweissteilen aus Aluminium oder seinen Legierungen und entsprechende Schweissteile
FR2915398B1 (fr) * 2007-04-25 2012-12-28 Lab Francais Du Fractionnement "ensemble de moyens pour le traitement d'une pathologie maligne, d'une maladie auto-immune ou d'une maladie infectieuse"
EP2495567A1 (de) * 2011-03-04 2012-09-05 Erasmus University Medical Center Rotterdam Verfahren und Vorrichtungen zur Überwachung von Störungen der Gewebehomöostase im gesamten Körper
US9517584B2 (en) 2013-12-18 2016-12-13 Eastman Chemical Company Articles comprising isosorbide and processes for their manufacture
US11421074B2 (en) 2015-01-30 2022-08-23 Zephyros, Inc. Adhesive material, and method of use thereof
EP3253814A1 (de) 2015-02-03 2017-12-13 Zephyros Inc. Einteilige epoxidbasierte zusammensetzung

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DE2742086A1 (de) * 1977-09-19 1979-03-29 Siemens Ag Vorrichtung zum trocknen der schlichte von glasseidefaeden o.dgl.
US4912045A (en) 1980-01-08 1990-03-27 Ortho Pharmaceutical Corporation Hybrid cell line for producing monoclonal antibody to a human monocyte, antigen, antibody and methods
US4434237A (en) 1982-03-31 1984-02-28 Dinarello Charles A Human leukocytic pyrogen test for the detection of exogenous fever-producing substances
US5112948A (en) 1986-10-10 1992-05-12 Jones C Michael Methods and compositions for inducing monocyte cytotoxicity
US5374549A (en) 1991-01-31 1994-12-20 Terumo Corporation Process of enriching adherent CD4+ T cells from monocyte depleted peripheral blood mononuclear cells with interleukin 2 and interleukin 4
WO1994026875A1 (en) * 1993-05-18 1994-11-24 I.D.M. Immuno-Designed Molecules New macrophages, process for preparing the same and their use as active substances of pharmaceutical compositions
FR2729570A1 (fr) * 1995-01-24 1996-07-26 Idm Immuno Designed Molecules Procede de preparation de macrophages actives, trousses et compositions pour la mise en oeuvre de ce procede

Also Published As

Publication number Publication date
FR2729570B1 (de) 1997-02-28
EP0806959B1 (de) 2002-11-13
US5804442A (en) 1998-09-08
CA2210449C (fr) 2003-03-18
AU4626596A (en) 1996-08-14
WO1996022781A1 (fr) 1996-08-01
FR2729570A1 (fr) 1996-07-26
ES2185759T3 (es) 2003-05-01
DE69624789D1 (de) 2002-12-19
US6221576B1 (en) 2001-04-24
JPH11505512A (ja) 1999-05-21
CA2210449A1 (fr) 1996-08-01
US6140122A (en) 2000-10-31
JP3537443B2 (ja) 2004-06-14
EP0806959A1 (de) 1997-11-19
DE69624789T2 (de) 2003-07-03
AU720285B2 (en) 2000-05-25

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