AU768081B2
(en)
*
|
1996-04-03 |
2003-12-04 |
Wellstat Therapeutics Corporation |
Inhibitor and stimulator of stem cell proliferation and uses thereof
|
AU3440797A
(en)
*
|
1996-07-01 |
1998-01-21 |
Novartis Ag |
Process of obtaining compositions enriched for hematopoietic stem cells and antibodies for use therein
|
AU7180398A
(en)
|
1996-11-13 |
1998-06-03 |
Morphogenesis, Inc. |
Antibody MG1 recognizing a small subset of human hematopoietic cells
|
CA2274469C
(en)
*
|
1996-12-10 |
2009-09-01 |
Tony Peled |
Serum-derived factor inducing cell differentiation and medical uses thereof
|
EP0848012A1
(de)
*
|
1996-12-13 |
1998-06-17 |
Roche Diagnostics GmbH |
Verwendung von Polypeptiden zur Behandlung von Thrombozytopenien
|
US7125714B2
(en)
*
|
1997-02-05 |
2006-10-24 |
Licentia Ltd. |
Progenitor cell materials and methods
|
AU6795498A
(en)
*
|
1997-04-08 |
1998-10-30 |
Pall Corporation |
Method of harvesting rare cells from blood products
|
US7361336B1
(en)
*
|
1997-09-18 |
2008-04-22 |
Ivan Bergstein |
Methods of cancer therapy targeted against a cancer stem line
|
US6153113A
(en)
*
|
1999-02-22 |
2000-11-28 |
Cobe Laboratories, Inc. |
Method for using ligands in particle separation
|
WO2001011011A2
(en)
|
1999-08-05 |
2001-02-15 |
Mcl Llc |
Multipotent adult stem cells and methods for isolation
|
US6790614B1
(en)
|
1999-11-19 |
2004-09-14 |
Novartis Ag |
Selectable cell surface marker genes
|
US7129326B2
(en)
*
|
2000-04-14 |
2006-10-31 |
Genencor International, Inc. |
Methods for selective targeting
|
ES2338097T3
(es)
*
|
2000-04-14 |
2010-05-04 |
Genencor International, Inc. |
Procedimiento de identificacion selectiva.
|
US6828145B2
(en)
|
2000-05-10 |
2004-12-07 |
Cedars-Sinai Medical Center |
Method for the isolation of stem cells by immuno-labeling with HLA/MHC gene product marker
|
US6632620B1
(en)
|
2000-06-22 |
2003-10-14 |
Andrew N. Makarovskiy |
Compositions for identification and isolation of stem cells
|
US20030068792A1
(en)
*
|
2000-12-14 |
2003-04-10 |
Yiyou Chen |
Targeted enzymes
|
US20030049689A1
(en)
*
|
2000-12-14 |
2003-03-13 |
Cynthia Edwards |
Multifunctional polypeptides
|
US20030147874A1
(en)
*
|
2000-12-14 |
2003-08-07 |
Volker Schellenberger |
Targeted enzyme prodrug therapy
|
US20080248544A1
(en)
*
|
2000-12-14 |
2008-10-09 |
Murray Christopher J |
Methods And Compositions For Grafting Functional Loops Into A Protein
|
US20030022249A1
(en)
*
|
2001-05-17 |
2003-01-30 |
Juergen Schmitz |
Antigen-binding fragments that recognize a subset of dendritic cells and methods of use thereof
|
US7129034B2
(en)
*
|
2001-10-25 |
2006-10-31 |
Cedars-Sinai Medical Center |
Differentiation of whole bone marrow
|
ATE438708T1
(de)
*
|
2001-11-15 |
2009-08-15 |
Childrens Medical Center |
Verfahren zur isolierung, expansion und differenzierung fötaler stammzellen aus chorionzotte, fruchtwasser und plazenta und therapeutische verwendungen davon
|
US7625752B2
(en)
*
|
2001-12-21 |
2009-12-01 |
Mount Sinai Hospital |
Cellular compositions and methods of making and using them
|
EP2107116A3
(de)
|
2002-06-12 |
2009-12-09 |
Genencor International, Inc. |
Verfahren zur Verbesserung der Bindungscharakteristika von Molekülen
|
WO2007116408A2
(en)
*
|
2006-04-11 |
2007-10-18 |
Nanodiagnostics Israel Ltd. |
Pluripotent stem cells characterized by expression of germline specific genes
|
US20110158966A1
(en)
*
|
2002-07-23 |
2011-06-30 |
Judith Seligman |
Stem cells characterized by expression of germline specific genes
|
CA2493768A1
(en)
*
|
2002-07-23 |
2004-01-29 |
Nanodiagnostics, Inc. |
Embryonic stem cell markers and uses thereof
|
US20040028661A1
(en)
*
|
2002-08-07 |
2004-02-12 |
Bartelmez Stephen H. |
Expansion of cells using thrombopoietin and anti-transforming growth factor-beta
|
ATE480550T1
(de)
*
|
2004-03-25 |
2010-09-15 |
California Inst Of Techn |
Hybridisierungskettenreaktion
|
EP1756267A2
(de)
|
2004-05-14 |
2007-02-28 |
Becton, Dickinson and Company |
Stammzellpopulationen und verwendungsverfahren
|
US20080233100A1
(en)
*
|
2004-06-30 |
2008-09-25 |
Yiyou Chen |
Targeted enzymes
|
JP4819809B2
(ja)
*
|
2004-07-28 |
2011-11-24 |
ユニベルシテ・ルネ・デカルト・パリ 5 |
血管幹細胞及びその使用
|
SI1799844T1
(sl)
*
|
2004-09-10 |
2010-04-30 |
Genencor Int |
Postopki za detektiranje tarŽŤ
|
WO2006044650A2
(en)
*
|
2004-10-15 |
2006-04-27 |
Genencor International, Inc. |
Competitive differential screening
|
WO2007001420A2
(en)
*
|
2004-10-22 |
2007-01-04 |
Genencor International, Inc. |
Isolating human antibodies
|
WO2006052991A2
(en)
|
2004-11-11 |
2006-05-18 |
The General Hosptial Corporation |
Parathyroid hormone receptor activation and stem and progenitor cell expansion
|
US20080044400A1
(en)
*
|
2004-12-09 |
2008-02-21 |
Volker Schellenberger |
Targeted enzyme prodrug therapy
|
US7727721B2
(en)
*
|
2005-03-08 |
2010-06-01 |
California Institute Of Technology |
Hybridization chain reaction amplification for in situ imaging
|
KR101004634B1
(ko)
*
|
2005-08-01 |
2011-01-04 |
뉴포텐셜, 인크. |
잠재력이 복원된 리프로그래밍된 세포의 제조
|
US7960357B2
(en)
*
|
2005-10-07 |
2011-06-14 |
California Institute Of Technology |
PKR activation via hybridization chain reaction
|
GEP20135796B
(en)
|
2006-03-07 |
2013-04-10 |
|
Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation
|
US20100172882A1
(en)
*
|
2007-01-11 |
2010-07-08 |
Glazer Peter M |
Compositions and methods for targeted inactivation of hiv cell surface receptors
|
JP2010516240A
(ja)
|
2007-01-18 |
2010-05-20 |
スオメン プナイネン リスティ,ヴェリパルベル |
ヒト細胞からの新規の炭水化物、ならびにその分析および修飾のための方法
|
JP2010516239A
(ja)
|
2007-01-18 |
2010-05-20 |
スオメン プナイネン リスティ,ヴェリパルベル |
細胞の産生に対する新規方法および試薬
|
WO2008106658A2
(en)
*
|
2007-03-01 |
2008-09-04 |
California Institute Of Technology |
TRIGGERED RNAi
|
US8574567B2
(en)
*
|
2007-05-03 |
2013-11-05 |
The Brigham And Women's Hospital, Inc. |
Multipotent stem cells and uses thereof
|
EP2155860B1
(de)
*
|
2007-05-03 |
2014-08-27 |
The Brigham and Women's Hospital, Inc. |
Multipotente stammzellen und ihre verwendung
|
EP2155770B1
(de)
|
2007-05-16 |
2013-10-16 |
California Institute of Technology |
Vielseitiges nukleinsäure-haarnadel-motiv zur programmierung biomolekularer selbstanordnungspfade
|
US8497364B2
(en)
*
|
2008-02-27 |
2013-07-30 |
California Institute Of Technology |
Triggered RNAi
|
US20100021904A1
(en)
*
|
2008-05-21 |
2010-01-28 |
Pierce Niles A |
Shielded cross-linking probes
|
US8241854B2
(en)
*
|
2008-05-22 |
2012-08-14 |
California Institute Of Technology |
Triggered RNAi
|
US20100021901A1
(en)
*
|
2008-05-22 |
2010-01-28 |
Peng Yin |
Compositions and methods for detecting analytes
|
HUE062339T2
(hu)
|
2009-02-13 |
2023-10-28 |
Immunomedics Inc |
Sejten belül hasítható kötést tartalmazó immunkonjugátumok
|
DK3329772T3
(da)
|
2009-07-15 |
2020-01-27 |
Calimmune Inc |
Dobbeltvektor til inhibering af human immundefektvirus
|
WO2011011500A1
(en)
|
2009-07-21 |
2011-01-27 |
Abt Holding Company |
Use of stem cells to reduce leukocyte extravasation
|
CN102482701B
(zh)
|
2009-09-16 |
2015-05-13 |
免疫医疗公司 |
I类抗-cea抗体及其使用
|
WO2011053989A2
(en)
|
2009-11-02 |
2011-05-05 |
Yale University |
Polymeric materials loaded with mutagenic and recombinagenic nucleic acids
|
WO2011068845A1
(en)
|
2009-12-02 |
2011-06-09 |
Immunomedics, Inc. |
Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
|
SG10201907877YA
(en)
|
2010-02-25 |
2019-09-27 |
Abt Holding Co |
Modulation of macrophage activation
|
WO2011133802A1
(en)
|
2010-04-21 |
2011-10-27 |
Helix Therapeutics, Inc. |
Compositions and methods for treatment of lysosomal storage disorders
|
WO2011133803A1
(en)
|
2010-04-21 |
2011-10-27 |
Helix Therapeutics, Inc. |
Compositions and methods for targeted inactivation of hiv cell surface receptors
|
US8658780B2
(en)
|
2010-05-18 |
2014-02-25 |
California Institute Of Technology |
Triggered covalent probes for imaging and silencing genetic expression
|
CA2802087A1
(en)
|
2010-06-15 |
2011-12-22 |
Cellular Dynamics International, Inc. |
A compendium of ready-built stem cell models for interrogation of biological response
|
EP2591093B1
(de)
|
2010-07-07 |
2018-11-28 |
FUJIFILM Cellular Dynamics, Inc. |
Endothelzellenproduktion durch programmierung
|
US8877438B2
(en)
|
2010-07-20 |
2014-11-04 |
California Institute Of Technology |
Self-assembled polynucleotide structure
|
US9834439B2
(en)
|
2010-07-20 |
2017-12-05 |
California Institute Of Technology |
Biomolecular self-assembly
|
US8962241B2
(en)
|
2010-07-20 |
2015-02-24 |
California Institute Of Technology |
Triggered molecular geometry based bioimaging probes
|
CN112516167A
(zh)
|
2010-08-12 |
2021-03-19 |
菲特治疗公司 |
改进的造血干细胞和祖细胞疗法
|
WO2012048276A2
(en)
|
2010-10-08 |
2012-04-12 |
Caridianbct, Inc. |
Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
|
CA2826386C
(en)
|
2011-02-08 |
2020-04-28 |
Cellular Dynamics International, Inc. |
Hematopoietic precursor cell production by programming
|
WO2012151199A1
(en)
|
2011-05-02 |
2012-11-08 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
SG10201914092XA
(en)
|
2011-06-06 |
2020-03-30 |
ReGenesys BVBA |
Expansion of stem cells in hollow fiber bioreactors
|
ES2710452T3
(es)
|
2011-06-10 |
2019-04-25 |
Bluebird Bio Inc |
Vectores de terapia génica para la adrenoleucodistrofia y la adrenomieloneuropatía
|
EP2739735A2
(de)
|
2011-08-01 |
2014-06-11 |
Alnylam Pharmaceuticals, Inc. |
Verfahren zur verbesserung der erfolgsquote von hämatopoetischen stammzellentransplantaten
|
AU2011377617B2
(en)
|
2011-09-23 |
2018-03-08 |
Bluebird Bio, Inc. |
Improved gene therapy methods
|
IN2014CN02518A
(de)
|
2011-09-30 |
2015-07-31 |
Bluebird Bio Inc |
|
ES2682255T3
(es)
|
2011-12-02 |
2018-09-19 |
Fate Therapeutics, Inc. |
Métodos mejorados de tratamiento de isquemia
|
US9452186B2
(en)
|
2011-12-02 |
2016-09-27 |
Fate Therapeutics, Inc. |
Enhanced stem cell composition
|
CN109513003A
(zh)
|
2012-08-14 |
2019-03-26 |
Ibc药品公司 |
用于治疗疾病的t-细胞重定向双特异性抗体
|
CN109554350B
(zh)
|
2012-11-27 |
2022-09-23 |
儿童医疗中心有限公司 |
用于胎儿血红蛋白再诱导的靶向bcl11a远端调控元件
|
JP6366111B2
(ja)
|
2012-12-13 |
2018-08-01 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
有効性の改善および毒性の減少のための、抗体およびsn−38からなるイムノコンジュゲートの投薬
|
CN105229144A
(zh)
|
2013-02-22 |
2016-01-06 |
细胞动力学国际有限公司 |
通过组合的遗传工程和化学工程经由正向编程产生肝细胞
|
US9943545B2
(en)
|
2013-03-15 |
2018-04-17 |
Fate Therapeutics, Inc. |
Stem cell culture media and methods of enhancing cell survival
|
US10851412B2
(en)
|
2013-03-15 |
2020-12-01 |
Fate Therapeutics, Inc. |
Cell potency assay for therapeutic potential
|
AU2014248167B2
(en)
|
2013-04-03 |
2019-10-10 |
FUJIFILM Cellular Dynamics, Inc. |
Methods and compositions for culturing endoderm progenitor cells in suspension
|
SG10201710638UA
(en)
|
2013-04-12 |
2018-01-30 |
Saverio Lafrancesca |
Improving organs for transplantation
|
ES2753323T3
(es)
|
2013-04-30 |
2020-04-08 |
Univ Leuven Kath |
Terapia celular para síndromes mielodisplásicos
|
US9856472B2
(en)
|
2013-07-01 |
2018-01-02 |
California Institute Of Technology |
Small conditional RNAs
|
US9789116B2
(en)
|
2013-10-15 |
2017-10-17 |
Case Western Reserve University |
Compositions and methods of modulating short-chain dehydrogenase activity
|
WO2015073918A1
(en)
|
2013-11-16 |
2015-05-21 |
Terumo Bct, Inc. |
Expanding cells in a bioreactor
|
MX2016010683A
(es)
|
2014-02-21 |
2017-05-11 |
Ibc Pharmaceuticals Inc |
Terapia para tratar enfermedades mediante la induccion de respuesta inmune de las células que expresan trop-2.
|
WO2015130416A1
(en)
|
2014-02-25 |
2015-09-03 |
Immunomedics, Inc. |
Humanized rfb4 anti-cd22 antibody
|
WO2015164228A1
(en)
|
2014-04-21 |
2015-10-29 |
Cellular Dynamics International, Inc. |
Hepatocyte production via forward programming by combined genetic and chemical engineering
|
CA2946309C
(en)
|
2014-04-25 |
2021-11-09 |
Michael MILSOM |
Synthetic bcl11a micrornas for treating hemoglobinopathies
|
US10238581B2
(en)
|
2014-05-09 |
2019-03-26 |
Yale University |
Hyperbranched polyglycerol-coated particles and methods of making and using thereof
|
US11918695B2
(en)
|
2014-05-09 |
2024-03-05 |
Yale University |
Topical formulation of hyperbranched polymer-coated particles
|
CA2953567C
(en)
|
2014-06-24 |
2023-09-05 |
Immunomedics, Inc. |
Anti-histone therapy for vascular necrosis in severe glomerulonephritis
|
PL3204018T3
(pl)
|
2014-10-07 |
2022-01-03 |
Immunomedics, Inc. |
Neoadiuwantowe zastosowanie koniugatów przeciwciało-lek
|
EP3770252A1
(de)
|
2015-01-26 |
2021-01-27 |
Fate Therapeutics, Inc. |
Zellen mit erhöhten immunregulatorischen eigenschaften und verfahren zu deren verwendung und herstellung
|
US9797907B2
(en)
|
2015-04-22 |
2017-10-24 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells
|
WO2016182917A1
(en)
|
2015-05-08 |
2016-11-17 |
Children's Medical Center Corporation |
Targeting bcl11a enhancer functional regions for fetal hemoglobin reinduction
|
CN107735104B
(zh)
|
2015-06-25 |
2022-05-03 |
免疫医疗公司 |
组合抗hla-dr抗体或抗trop-2抗体与微管抑制剂、parp抑制剂、布鲁顿激酶抑制剂或磷酸肌醇3-激酶抑制剂使癌症治疗结果显著改善
|
EP3316885B1
(de)
|
2015-07-01 |
2021-06-23 |
Immunomedics, Inc. |
Antikörper-sn-38-immunkonjugate mit einem cl2a-linker
|
KR20180033537A
(ko)
|
2015-07-21 |
2018-04-03 |
더 칠드런스 메디칼 센터 코포레이션 |
Pd-l1 발현 조혈 줄기 세포 및 용도
|
KR20180110112A
(ko)
|
2016-02-12 |
2018-10-08 |
블루버드 바이오, 인코포레이티드. |
Vcn 인핸서 조성물 및 이의 사용 방법
|
US11326183B2
(en)
|
2016-02-12 |
2022-05-10 |
Bluebird Bio, Inc. |
VCN enhancer compositions and methods of using the same
|
AU2017221424A1
(en)
|
2016-02-16 |
2018-09-20 |
Yale University |
Compositions and methods for treatment of cystic fibrosis
|
JP2019508037A
(ja)
|
2016-02-16 |
2019-03-28 |
イェール ユニバーシティーYale Universit |
標的化遺伝子編集を増強するための組成物およびその使用方法
|
DK3481843T3
(en)
|
2016-07-05 |
2022-02-07 |
California Inst Of Techn |
Fractional initiator hybridization chain reaction
|
US10815519B2
(en)
|
2016-08-30 |
2020-10-27 |
California Institute Of Technology |
Immunohistochemistry via hybridization chain reaction
|
US11690847B2
(en)
|
2016-11-30 |
2023-07-04 |
Case Western Reserve University |
Combinations of 15-PGDH inhibitors with corticosteroids and/or TNF inhibitors and uses thereof
|
WO2018145080A1
(en)
|
2017-02-06 |
2018-08-09 |
Case Western Reserve University |
Compositions and methods of modulating short-chain dehydrogenase activity
|
EP3583203B1
(de)
|
2017-02-15 |
2023-11-01 |
2seventy bio, Inc. |
Spenderreparaturtemplates für multiplex-genomeditierung
|
US11261441B2
(en)
|
2017-03-29 |
2022-03-01 |
Bluebird Bio, Inc. |
Vectors and compositions for treating hemoglobinopathies
|
WO2018187493A1
(en)
|
2017-04-04 |
2018-10-11 |
Yale University |
Compositions and methods for in utero delivery
|
AU2018261637A1
(en)
|
2017-05-03 |
2019-12-12 |
Biomarin Pharmaceutical Inc. |
Improved lentiviruses for transduction of hematopoietic stem cells.
|
WO2018218135A1
(en)
|
2017-05-25 |
2018-11-29 |
The Children's Medical Center Corporation |
Bcl11a guide delivery
|
WO2019060708A1
(en)
|
2017-09-22 |
2019-03-28 |
The Children's Medical Center Corporation |
TREATMENT OF TYPE 1 DIABETES AND AUTOIMMUNE DISEASES OR DISORDERS
|
KR20210054547A
(ko)
|
2018-08-31 |
2021-05-13 |
예일 유니버시티 |
삼중체 및 뉴클레아제 기반 유전자 편집을 향상시키기 위한 조성물 및 방법
|
EP3844287B1
(de)
|
2018-08-31 |
2024-05-22 |
Yale University |
Zusammensetzungen und verfahren zur verbesserung der oligonukleotidbasierten geneditierung
|
US20210340562A1
(en)
|
2018-10-19 |
2021-11-04 |
Board Of Regents, The University Of Texas System |
Engineered long interspersed element (line) transposons and methods of use
|
MX2021005982A
(es)
|
2018-11-21 |
2021-09-23 |
Univ Case Western Reserve |
Composiciones y metodos para modular la actividad de deshidrogenasas de cadena corta.
|
WO2020112195A1
(en)
|
2018-11-30 |
2020-06-04 |
Yale University |
Compositions, technologies and methods of using plerixafor to enhance gene editing
|
CA3142521A1
(en)
|
2019-06-17 |
2020-12-24 |
Vertex Pharmaceuticals Incorporated |
Compositions and methods for editing beta-globin for treatment of hemaglobinopathies
|
WO2020257779A1
(en)
|
2019-06-21 |
2020-12-24 |
Yale University |
Hydroxymethyl-modified gamma-pna compositions and methods of use thereof
|
WO2020257776A1
(en)
|
2019-06-21 |
2020-12-24 |
Yale University |
Peptide nucleic acid compositions with modified hoogsteen binding segments and methods of use thereof
|
WO2021013669A1
(en)
*
|
2019-07-24 |
2021-01-28 |
Miltenyi Biotec B.V. & Co. KG |
Assay for identifing colony-forming cells
|
WO2021022161A1
(en)
|
2019-07-31 |
2021-02-04 |
Yale University |
Compositions and methods for treating sickle cell disease
|
CN115151275A
(zh)
|
2019-08-30 |
2022-10-04 |
耶鲁大学 |
用于向细胞递送核酸的组合物和方法
|
AU2021275122A1
(en)
|
2020-05-20 |
2022-12-15 |
Board Of Regents Of The University Of Texas System |
Compositions and methods of modulating short-chain dehydrogenase activity
|
EP4204002A1
(de)
|
2020-08-31 |
2023-07-05 |
Yale University |
Zusammensetzungen und verfahren zur abgabe von nukleinsäuren an zellen
|
US20220228142A1
(en)
|
2020-12-17 |
2022-07-21 |
Vertex Pharmaceuticals Incorporated |
Compositions and methods for editing beta-globin for treatment of hemaglobinopathies
|
US11873485B2
(en)
|
2021-01-26 |
2024-01-16 |
California Institute Of Technology |
Allosteric conditional guide RNAs for cell-selective regulation of CRISPR/Cas
|
WO2022239720A1
(ja)
|
2021-05-10 |
2022-11-17 |
公益財団法人川崎市産業振興財団 |
抗原への結合親和性を低減させた抗体
|
WO2022261115A1
(en)
|
2021-06-07 |
2022-12-15 |
Yale University |
Peptide nucleic acids for spatiotemporal control of crispr-cas binding
|
WO2024020597A1
(en)
|
2022-07-22 |
2024-01-25 |
The Johns Hopkins University |
Dendrimer-enabled targeted intracellular crispr/cas system delivery and gene editing
|
WO2024081736A2
(en)
|
2022-10-11 |
2024-04-18 |
Yale University |
Compositions and methods of using cell-penetrating antibodies
|