ATE223043T1 - Verfahren und reagenszusammensetzung zur durchführung von differenzierenden leukocytzählungen in frischen und gealteren vollblutproben, auf der grundlage der bereitsvorhandenen peroxidaseaktivität der leukocyten - Google Patents

Verfahren und reagenszusammensetzung zur durchführung von differenzierenden leukocytzählungen in frischen und gealteren vollblutproben, auf der grundlage der bereitsvorhandenen peroxidaseaktivität der leukocyten

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Publication number
ATE223043T1
ATE223043T1 AT96106957T AT96106957T ATE223043T1 AT E223043 T1 ATE223043 T1 AT E223043T1 AT 96106957 T AT96106957 T AT 96106957T AT 96106957 T AT96106957 T AT 96106957T AT E223043 T1 ATE223043 T1 AT E223043T1
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AT
Austria
Prior art keywords
reagent composition
blood samples
fresh
analysis
whole blood
Prior art date
Application number
AT96106957T
Other languages
English (en)
Inventor
Michael J Malin
Phyllis Shapiro
John F Cremins
Original Assignee
Bayer Ag
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Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE223043T1 publication Critical patent/ATE223043T1/de

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/106664—Blood serum or blood plasma standard or control
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Ecology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT96106957T 1995-05-16 1996-05-03 Verfahren und reagenszusammensetzung zur durchführung von differenzierenden leukocytzählungen in frischen und gealteren vollblutproben, auf der grundlage der bereitsvorhandenen peroxidaseaktivität der leukocyten ATE223043T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/442,491 US5639630A (en) 1995-05-16 1995-05-16 Method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples, based on intrinsic peroxidase activity of leukocytes

Publications (1)

Publication Number Publication Date
ATE223043T1 true ATE223043T1 (de) 2002-09-15

Family

ID=23756987

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96106957T ATE223043T1 (de) 1995-05-16 1996-05-03 Verfahren und reagenszusammensetzung zur durchführung von differenzierenden leukocytzählungen in frischen und gealteren vollblutproben, auf der grundlage der bereitsvorhandenen peroxidaseaktivität der leukocyten

Country Status (12)

Country Link
US (1) US5639630A (de)
EP (1) EP0743519B1 (de)
JP (1) JP4361142B2 (de)
KR (1) KR960042055A (de)
AT (1) ATE223043T1 (de)
AU (1) AU699086C (de)
CA (1) CA2173519A1 (de)
DE (1) DE69623174T2 (de)
ES (1) ES2181821T3 (de)
IL (1) IL117862A (de)
PT (1) PT743519E (de)
TW (1) TW448295B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888752A (en) * 1995-05-16 1999-03-30 Bayer Corporation Universal rinse reagent and method for use in hematological analyses of whole blood samples
US5843608A (en) * 1995-06-08 1998-12-01 Coulter International Corp. Reagent and method for differential determination of leukocytes in blood
US5817518A (en) * 1995-12-18 1998-10-06 Coulter International Corp. Reagent and method for differential determination of leukocytes in blood
US5830701A (en) * 1997-03-28 1998-11-03 Tao Medical Electronics Co., Ltd. Method of detecting hematopoietic progenitor cells
JP3830613B2 (ja) * 1997-04-18 2006-10-04 シスメックス株式会社 血液中の白血球及びヘモグロビン濃度測定試薬
US5858794A (en) * 1997-05-13 1999-01-12 Bayer Corporation Cyanide-containing hemoglobin reagent composition and method providing acceptable precision, accuracy and freedom from white cell interference on automated hematology analyzers
US8071384B2 (en) * 1997-12-22 2011-12-06 Roche Diagnostics Operations, Inc. Control and calibration solutions and methods for their use
US7494816B2 (en) 1997-12-22 2009-02-24 Roche Diagnostic Operations, Inc. System and method for determining a temperature during analyte measurement
CA2335747A1 (en) * 1998-06-30 2000-01-06 Lamina, Inc. Cytological and histological fixative composition and methods of use
FR2782166B1 (fr) * 1998-08-04 2000-10-06 Abx Sa Reactif pour la mesure de l'hemoglobine et la determination des leucocytes dans un echantillon de sang
US6599713B1 (en) 1999-03-29 2003-07-29 Asahi Kasei Kabushiki Kaisha Method for quantitating leukocyte count in whole blood sample
US6225124B1 (en) * 1999-06-02 2001-05-01 Sysmex Corporation Diluting reagent and method compelling time-independent consistency in MCV assay
US6632676B1 (en) * 1999-09-24 2003-10-14 Clinical Diagnostic Solutions Multi-purpose reagent system and method for enumeration of red blood cells, white blood cells and thrombocytes and differential determination of white blood cells
US7282347B2 (en) 2000-07-04 2007-10-16 Fisher Bioimage Aps Method for extracting quantitative information relating to interactions between cellular components
EP1422509A1 (de) * 2002-11-01 2004-05-26 Streck Laboratories, Inc. Lysierungsreagenz und Verfahren zum Lysieren von Roten Blutkörperchen für die Hämatologie
US7723099B2 (en) * 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
US7803523B2 (en) * 2004-08-27 2010-09-28 University Health Network Whole blood preparation for cytometric analysis of cell signaling pathways
EP1794596B1 (de) * 2004-09-01 2013-11-06 Maine Standards Company LLC Neue stabile lipidstandards
US7625757B2 (en) * 2006-01-27 2009-12-01 Sysmex Corporation Reagent for immature leukocyte analysis and reagent kit
CN101078720B (zh) * 2006-05-22 2010-12-01 深圳迈瑞生物医疗电子股份有限公司 一种改进的用于对白细胞进行分类的试剂及方法
CN101078721B (zh) * 2006-05-23 2010-12-22 深圳迈瑞生物医疗电子股份有限公司 对白细胞进行分类的试剂及方法
ATE452336T1 (de) 2006-06-06 2010-01-15 Hoffmann La Roche Gebrauchsfertiges sammelgefäss für vollblut
US20080026366A1 (en) * 2006-06-07 2008-01-31 Newcomer Supply, Inc. Biological fixative and method of using the biological fixative
US7449337B2 (en) * 2007-01-24 2008-11-11 Idexx Laboratories, Inc. Lytic reagent and method for leukocytes differential in whole blood
CN101311725B (zh) * 2007-05-25 2014-03-26 深圳迈瑞生物医疗电子股份有限公司 一种五分类白细胞质控物及其制备方法
CN101349644B (zh) * 2007-07-20 2012-06-27 深圳迈瑞生物医疗电子股份有限公司 一种白细胞分类试剂和其使用方法
US9909098B2 (en) 2007-08-06 2018-03-06 The Regents Of The University Of California Methods of tissue-based diagnosis
US9814422B2 (en) 2007-08-06 2017-11-14 The Regents Of The University Of California Compositions for solubilizing cells and/or tissue
US8642664B2 (en) 2007-08-06 2014-02-04 Samir Mitragotri Composition for solubilizing tissue and cells comprising N-tetradecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate and polyoxyethylene (10) cetyl ether
US8102161B2 (en) * 2007-09-25 2012-01-24 Tdk Corporation Stable output in a switching power supply by smoothing the output of the secondary coil
CN105440725A (zh) * 2008-01-04 2016-03-30 深圳迈瑞生物医疗电子股份有限公司 不对称菁类荧光染料，组合物及在生物样品染色中的用途
CN101602762B (zh) * 2008-06-10 2013-10-16 深圳迈瑞生物医疗电子股份有限公司 不对称菁类化合物、其制备方法及应用
CN101726579B (zh) * 2008-10-17 2014-06-18 深圳迈瑞生物医疗电子股份有限公司 血液检测试剂和方法
CN101750274B (zh) * 2008-12-17 2014-06-25 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒以及白细胞分类计数的方法
EP2396654B1 (de) 2009-02-13 2016-02-10 The Regents of The University of California Zusammensetzung und Verfahren für die gewebebasierte Diagnose
CN101988082B (zh) * 2009-07-31 2015-04-08 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法
US9091677B2 (en) 2010-08-09 2015-07-28 Beckman Coulter, Inc. Isotonic buffered composition and method that enables counting of cells
KR102035881B1 (ko) 2012-03-30 2019-10-23 세키스이 메디칼 가부시키가이샤 혈액시료 내의 물질 측정 방법
MX369625B (es) * 2012-05-16 2019-11-14 Univ California Composiciones para solubilizar celulas y/o tejido.
JP6692743B2 (ja) * 2013-03-12 2020-05-13 アボット・ラボラトリーズＡｂｂｏｔｔ Ｌａｂｏｒａｔｏｒｉｅｓ 白血球を分析するための試薬、システム、及び方法
BE1021926B1 (nl) * 2014-04-01 2016-01-27 FertiPro N.V. Werkijze voor semenanalyse
WO2019111355A1 (ja) * 2017-12-06 2019-06-13 オリンパス株式会社 学習モデル作成方法、画像処理方法、学習モデル作成装置、画像処理装置、学習モデル作成プログラム、及び画像処理プログラム
JP7143678B2 (ja) * 2018-08-24 2022-09-29 東ソー株式会社 標的細胞を検出する方法
CN114127535A (zh) * 2019-06-19 2022-03-01 深圳迈瑞动物医疗科技有限公司 一种细胞分析仪、基于阻抗法对白细胞进行分类的方法及计算机可读存储介质
CN111239120A (zh) * 2020-02-26 2020-06-05 绍兴市人民医院 一种血液钙离子检测试纸

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3741875A (en) * 1970-10-30 1973-06-26 Mount Sinai Res Foundation Inc Process and apparatus for obtaining a differential white blood cell count
US4099917A (en) * 1977-07-21 1978-07-11 Technicon Instruments Corporation Process for preparing a cell suspension from blood for discrimination of white blood cells and platelets from other blood particles
US4506018A (en) * 1982-12-30 1985-03-19 Becton, Dickinson And Company Blood diluent
CA1255197A (en) * 1984-09-24 1989-06-06 Joseph L. Orlik Leukocyte differentiation composition and method
US4801549A (en) * 1985-09-06 1989-01-31 Technicon Instruments Corporation Method for the determination of a differential white blood cell count
AU602129B2 (en) * 1985-09-06 1990-10-04 Technicon Instruments Corportion Method for the determination of a differential white blood cell count
US4978624A (en) * 1985-09-06 1990-12-18 Technicon Instruments Corporation Reagent for the determination of a differential white blood cell count
US5426029A (en) * 1986-03-31 1995-06-20 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using leukocyte surface antigens
US5262302A (en) * 1987-03-13 1993-11-16 Coulter Corporation Method for screening white blood cells
DE3855153T2 (de) * 1987-05-29 1996-11-14 Toa Medical Electronics Verfahren zum klassifizieren von leukozyten und reagenzien
US5389549A (en) * 1987-05-29 1995-02-14 Toa Medical Electronics Co., Ltd. Method for classifying leukocytes and a reagent used therefor
JP2619900B2 (ja) * 1988-01-27 1997-06-11 東亜医用電子株式会社 血液中の白血球およびヘモグロビンの測定用試薬および方法
CA2016699C (en) * 1989-05-15 2003-11-18 Paul N. Marshall Lytic agents and uses thereof
US5116734A (en) * 1989-09-01 1992-05-26 Digene Diagnostics, Inc. Highly sensitive method for detecting peroxidase
IT8921788A0 (it) * 1989-09-21 1989-09-21 Diesse Diagnostica Reattivo utile per la rilevazione e la determinazione quantitativa dei leucociti in fluidi biologici.
FR2654744B1 (fr) * 1989-11-20 1992-03-13 Abx Sa Reactif et methode d'utilisation de celui-ci pour la determination automatique en cytometrie de flux d'au moins une sous-population leucocytaire a partir du sang total.
US5227304A (en) * 1991-01-16 1993-07-13 Sequoia Turner Corporation Method for counting whole blood diluent and detergent reagent system
JP3048260B2 (ja) * 1991-07-29 2000-06-05 シスメックス株式会社 白血球分類計数用試料調製方法
US5525461A (en) * 1991-11-01 1996-06-11 T Cell Diagnostics, Inc. Therapeutic and diagnostic methods using total leukocyte surface antigens
JP3467310B2 (ja) * 1994-04-21 2003-11-17 シスメックス株式会社 白血球分析用試薬及び白血球の分類方法

Also Published As

Publication number Publication date
KR960042055A (ko) 1996-12-19
EP0743519A2 (de) 1996-11-20
IL117862A (en) 1999-12-22
TW448295B (en) 2001-08-01
EP0743519B1 (de) 2002-08-28
JPH08308593A (ja) 1996-11-26
JP4361142B2 (ja) 2009-11-11
PT743519E (pt) 2002-12-31
DE69623174D1 (de) 2002-10-02
AU5226296A (en) 1996-11-28
CA2173519A1 (en) 1996-11-17
US5639630A (en) 1997-06-17
DE69623174T2 (de) 2002-12-19
AU699086B2 (en) 1998-11-19
ES2181821T3 (es) 2003-03-01
IL117862A0 (en) 1996-08-04
AU699086C (en) 2001-06-21
EP0743519A3 (de) 1998-07-29

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