ATE218882T1 - Gleichzeitige verarbeitung von interleukin-3 mutanten und kolonie stimulierungsfactor - Google Patents

Gleichzeitige verarbeitung von interleukin-3 mutanten und kolonie stimulierungsfactor

Info

Publication number
ATE218882T1
ATE218882T1 AT95908732T AT95908732T ATE218882T1 AT E218882 T1 ATE218882 T1 AT E218882T1 AT 95908732 T AT95908732 T AT 95908732T AT 95908732 T AT95908732 T AT 95908732T AT E218882 T1 ATE218882 T1 AT E218882T1
Authority
AT
Austria
Prior art keywords
interleukin
mutants
simultaneous processing
stimulation factor
colony stimulation
Prior art date
Application number
AT95908732T
Other languages
English (en)
Inventor
Christopher S Bauer
Mark Allen Abrams
Sarah Ruth Braford-Goldberg
Maire Helena Caparon
Alan Michael Easton
Barbara Kure Klein
John Patrick Mckearn
Peter O Olins
Kumnan Paik
John Warren Thomas
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of ATE218882T1 publication Critical patent/ATE218882T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5403—IL-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1816—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT95908732T 1994-02-04 1995-02-02 Gleichzeitige verarbeitung von interleukin-3 mutanten und kolonie stimulierungsfactor ATE218882T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/191,973 US5772992A (en) 1992-11-24 1994-02-04 Compositions for co-administration of interleukin-3 mutants and other cytokines and hematopoietic factors
PCT/US1995/001183 WO1995020976A1 (en) 1994-02-04 1995-02-02 Co-administration of interleukin-3 mutants with colony stimulating factors

Publications (1)

Publication Number Publication Date
ATE218882T1 true ATE218882T1 (de) 2002-06-15

Family

ID=22707677

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95908732T ATE218882T1 (de) 1994-02-04 1995-02-02 Gleichzeitige verarbeitung von interleukin-3 mutanten und kolonie stimulierungsfactor

Country Status (11)

Country Link
US (3) US5772992A (de)
EP (2) EP1199080A3 (de)
JP (1) JPH09508625A (de)
AT (1) ATE218882T1 (de)
AU (1) AU1695395A (de)
CA (1) CA2182473A1 (de)
DE (1) DE69527041T2 (de)
DK (1) DK0741576T3 (de)
ES (1) ES2180624T3 (de)
PT (1) PT741576E (de)
WO (1) WO1995020976A1 (de)

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Also Published As

Publication number Publication date
DE69527041D1 (de) 2002-07-18
JPH09508625A (ja) 1997-09-02
US5997860A (en) 1999-12-07
CA2182473A1 (en) 1995-08-10
US5997857A (en) 1999-12-07
ES2180624T3 (es) 2003-02-16
EP1199080A3 (de) 2003-11-26
US5772992A (en) 1998-06-30
EP0741576A1 (de) 1996-11-13
EP0741576B1 (de) 2002-06-12
WO1995020976A1 (en) 1995-08-10
EP1199080A2 (de) 2002-04-24
DE69527041T2 (de) 2002-12-19
DK0741576T3 (da) 2002-10-14
AU1695395A (en) 1995-08-21
PT741576E (pt) 2002-09-30

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Legal Events

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UEP Publication of translation of european patent specification
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