ATE216780T1 - Bestimmung von steroiden durch kompetitiven immunoassay - Google Patents

Bestimmung von steroiden durch kompetitiven immunoassay

Info

Publication number
ATE216780T1
ATE216780T1 AT96908511T AT96908511T ATE216780T1 AT E216780 T1 ATE216780 T1 AT E216780T1 AT 96908511 T AT96908511 T AT 96908511T AT 96908511 T AT96908511 T AT 96908511T AT E216780 T1 ATE216780 T1 AT E216780T1
Authority
AT
Austria
Prior art keywords
steroid
solid phase
kit
conjugate
mixture
Prior art date
Application number
AT96908511T
Other languages
English (en)
Inventor
Gregg T Williams
William R Groskopf
Harold N Baker
Dalmacio A Agdeppa
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE216780T1 publication Critical patent/ATE216780T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/806—Fertility tests
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/906—Fertility tests

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT96908511T 1995-03-03 1996-02-26 Bestimmung von steroiden durch kompetitiven immunoassay ATE216780T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/398,226 US5663054A (en) 1995-03-03 1995-03-03 Determination of steroids by competitive immunoassay
PCT/US1996/002495 WO1996027800A1 (en) 1995-03-03 1996-02-26 Determination of steroids by competitive immunoassay

Publications (1)

Publication Number Publication Date
ATE216780T1 true ATE216780T1 (de) 2002-05-15

Family

ID=23574524

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96908511T ATE216780T1 (de) 1995-03-03 1996-02-26 Bestimmung von steroiden durch kompetitiven immunoassay

Country Status (8)

Country Link
US (3) US5663054A (de)
EP (1) EP0813684B1 (de)
JP (1) JP3640970B2 (de)
AT (1) ATE216780T1 (de)
CA (1) CA2214085A1 (de)
DE (1) DE69620876T2 (de)
ES (1) ES2176445T3 (de)
WO (1) WO1996027800A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5854009A (en) * 1995-09-19 1998-12-29 Immuna Care Corporation Method of detecting estrogen-sensitive pathologies
US5977319A (en) * 1996-10-21 1999-11-02 Cambridge Antibody Technology Limited Specific binding members for estradiol; materials and methods
US6300082B1 (en) * 1998-03-20 2001-10-09 Ia, Inc. Method and apparatus for measurement of the effect of test compounds on signal transduction at the level of biological receptors
CA2283597C (en) 1998-10-02 2008-02-05 Ortho-Clinical Diagnostics, Inc. Reduced cortisol conjugates
US6174665B1 (en) 1999-09-10 2001-01-16 Biex, Inc. Hormone replacement therapy monitoring
WO2001020339A1 (en) * 1999-09-10 2001-03-22 Biex, Inc. Hormone replacement therapy monitoring
US7410807B2 (en) * 2000-07-24 2008-08-12 D Aurora Vito J Pregnancy and sex identification test based on saliva or other bodily fluids
US20030124618A1 (en) * 2001-12-04 2003-07-03 Lattec I/S Device for analysing analyte compounds and use hereof
JP3637392B2 (ja) * 2002-04-08 2005-04-13 独立行政法人産業技術総合研究所 燃料電池
JP2006506445A (ja) 2002-08-28 2006-02-23 ホリス − イーデン ファーマスーティカルズ、 インコーポレイテッド 治療処置の方法
US20060068501A1 (en) * 2004-09-30 2006-03-30 Nj International Llc Apparatus and methods for steroid hormone testing
US8206944B2 (en) * 2006-01-19 2012-06-26 Lattec I/S Dry stick device construction and method for determining an analyte in a sample using said dry stick device
PL1982183T3 (pl) 2006-01-19 2012-11-30 Lattec I/S Urządzenie suchego paska i sposób oznaczania analitu w próbce
US20100105071A1 (en) * 2007-02-28 2010-04-29 Children's Medical Center Corporation Methods for predicting the onset of menarche
JP5701666B2 (ja) * 2011-04-14 2015-04-15 株式会社Ｌｓｉメディエンス 高親和性抗ハプテンポリクローナル抗体の作製法
WO2013025532A2 (en) * 2011-08-12 2013-02-21 Siemens Healthcare Diagnostics Inc. Detection of sex steroids
JP6221466B2 (ja) * 2013-07-29 2017-11-01 東ソー株式会社 ハプテンの測定方法
GB201317458D0 (en) 2013-10-02 2013-11-13 Spd Swiss Prec Diagnostics Gmbh Improved pregnancy test device and method
WO2016014162A1 (en) 2014-07-25 2016-01-28 Becton, Dickinson And Company Analyte test strip assays, and test strips and kits for use in practicing the same
US10794920B2 (en) 2015-04-02 2020-10-06 Spd Swiss Precision Diagnostics Gmbh Pregnancy test device and method
SG11201911598WA (en) 2017-06-05 2020-01-30 ObsEva SA Gonadotropin-releasing hormone antagonist dosing regimens for the treatment of endometriosis

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282325A (en) * 1971-05-14 1981-08-04 Syva Company Enzyme bound corticosteroids
US4275149A (en) * 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
JPS60260592A (ja) * 1984-06-08 1985-12-23 Teikoku Hormone Mfg Co Ltd ステロイド測定用抗原
EP0200960A1 (de) * 1985-05-08 1986-11-12 Abbott Laboratories Fluoreszenzpolarisationsimmunoassay auf Gesamtöstriol
US4962192A (en) * 1986-07-17 1990-10-09 Board Of Governors Of Wayne State University Chemiluminescent 1,2-dioxetane compounds
US4857652A (en) * 1986-07-17 1989-08-15 Board Of Governors Of Wayne State University Chemiluminescent 1,2-dioxetane compounds
BR8707399A (pt) * 1986-07-24 1988-09-13 Quest Systems Inc Metodo de detectar uma substancia usando decomposicao enzimaticamente induzida de dioxetanos
JPH0633315B2 (ja) * 1988-01-25 1994-05-02 ベーリンガー・マンハイム・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング ハプテン誘導体、その製法、ハプテン／蛋白質―接合体、その製法、抗体の製法及びイムノアッセイの標識酵素
FR2627588A1 (fr) * 1988-02-24 1989-08-25 Ire Medgenix Sa Procede de dosage immunologique d'une substance de structure haptenique
JPH02213766A (ja) * 1989-02-15 1990-08-24 Mochida Pharmaceut Co Ltd 免疫測定用試薬および免疫測定器具
GB8926407D0 (en) * 1989-11-22 1990-01-10 Gen Electric Plc Polymers
US5342760A (en) * 1992-06-10 1994-08-30 Abbott Laboratories Determination of estradiol by competitive immunoassay
US5395938A (en) * 1992-08-21 1995-03-07 Nichols Institute Diagnostics Biotinylated chemiluminescent labels and their conjugates, assays and assay kits
US5491071A (en) * 1993-08-03 1996-02-13 Abbott Laboratories Reagents and methods for the detection and quantification of testosterone in fluid samples

Also Published As

Publication number Publication date
US5663054A (en) 1997-09-02
DE69620876T2 (de) 2002-12-12
WO1996027800A1 (en) 1996-09-12
CA2214085A1 (en) 1996-09-12
EP0813684B1 (de) 2002-04-24
ES2176445T3 (es) 2002-12-01
EP0813684A1 (de) 1997-12-29
JPH11501397A (ja) 1999-02-02
US6201141B1 (en) 2001-03-13
DE69620876D1 (de) 2002-05-29
US5932431A (en) 1999-08-03
JP3640970B2 (ja) 2005-04-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee