DE69620876D1 - Bestimmung von steroiden durch kompetitiven immunoassay - Google Patents
Bestimmung von steroiden durch kompetitiven immunoassayInfo
- Publication number
- DE69620876D1 DE69620876D1 DE69620876T DE69620876T DE69620876D1 DE 69620876 D1 DE69620876 D1 DE 69620876D1 DE 69620876 T DE69620876 T DE 69620876T DE 69620876 T DE69620876 T DE 69620876T DE 69620876 D1 DE69620876 D1 DE 69620876D1
- Authority
- DE
- Germany
- Prior art keywords
- steroid
- solid phase
- kit
- conjugate
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/806—Fertility tests
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/906—Fertility tests
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Endocrinology (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/398,226 US5663054A (en) | 1995-03-03 | 1995-03-03 | Determination of steroids by competitive immunoassay |
PCT/US1996/002495 WO1996027800A1 (en) | 1995-03-03 | 1996-02-26 | Determination of steroids by competitive immunoassay |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69620876D1 true DE69620876D1 (de) | 2002-05-29 |
DE69620876T2 DE69620876T2 (de) | 2002-12-12 |
Family
ID=23574524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69620876T Expired - Fee Related DE69620876T2 (de) | 1995-03-03 | 1996-02-26 | Bestimmung von steroiden durch kompetitiven immunoassay |
Country Status (8)
Country | Link |
---|---|
US (3) | US5663054A (de) |
EP (1) | EP0813684B1 (de) |
JP (1) | JP3640970B2 (de) |
AT (1) | ATE216780T1 (de) |
CA (1) | CA2214085A1 (de) |
DE (1) | DE69620876T2 (de) |
ES (1) | ES2176445T3 (de) |
WO (1) | WO1996027800A1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5854009A (en) * | 1995-09-19 | 1998-12-29 | Immuna Care Corporation | Method of detecting estrogen-sensitive pathologies |
US5977319A (en) * | 1996-10-21 | 1999-11-02 | Cambridge Antibody Technology Limited | Specific binding members for estradiol; materials and methods |
US6300082B1 (en) * | 1998-03-20 | 2001-10-09 | Ia, Inc. | Method and apparatus for measurement of the effect of test compounds on signal transduction at the level of biological receptors |
CA2283597C (en) | 1998-10-02 | 2008-02-05 | Ortho-Clinical Diagnostics, Inc. | Reduced cortisol conjugates |
US6174665B1 (en) | 1999-09-10 | 2001-01-16 | Biex, Inc. | Hormone replacement therapy monitoring |
WO2001020339A1 (en) * | 1999-09-10 | 2001-03-22 | Biex, Inc. | Hormone replacement therapy monitoring |
US7410807B2 (en) * | 2000-07-24 | 2008-08-12 | D Aurora Vito J | Pregnancy and sex identification test based on saliva or other bodily fluids |
US20030124618A1 (en) * | 2001-12-04 | 2003-07-03 | Lattec I/S | Device for analysing analyte compounds and use hereof |
JP3637392B2 (ja) * | 2002-04-08 | 2005-04-13 | 独立行政法人産業技術総合研究所 | 燃料電池 |
CA2496867A1 (en) | 2002-08-28 | 2004-03-11 | Hollis-Eden Pharmaceuticals, Inc. | Therapeutic treatment methods |
US20060068501A1 (en) * | 2004-09-30 | 2006-03-30 | Nj International Llc | Apparatus and methods for steroid hormone testing |
PL1982183T3 (pl) * | 2006-01-19 | 2012-11-30 | Lattec I/S | Urządzenie suchego paska i sposób oznaczania analitu w próbce |
DK1982182T3 (da) * | 2006-01-19 | 2012-05-14 | Lattec I S | Hidtil ukendt tør-stick-indretningskonstruktion og fremgangsmåde til bestemmelse af en analyt i en prøve under anvendelse af denne tør-stick-indretning |
WO2008106149A1 (en) * | 2007-02-28 | 2008-09-04 | Children's Medical Center Corporation | Methods for predicting the onset of menarche |
JP5701666B2 (ja) * | 2011-04-14 | 2015-04-15 | 株式会社Lsiメディエンス | 高親和性抗ハプテンポリクローナル抗体の作製法 |
ES2671238T3 (es) * | 2011-08-12 | 2018-06-05 | Siemens Healthcare Diagnostics Inc. | Detección de esteroides sexuales |
JP6221466B2 (ja) * | 2013-07-29 | 2017-11-01 | 東ソー株式会社 | ハプテンの測定方法 |
GB201317458D0 (en) * | 2013-10-02 | 2013-11-13 | Spd Swiss Prec Diagnostics Gmbh | Improved pregnancy test device and method |
CA2950166C (en) | 2014-07-25 | 2023-08-01 | Becton, Dickinson And Company | Analyte test strip assays, and test strips and kits for use in practicing the same |
EP3278114A1 (de) | 2015-04-02 | 2018-02-07 | Swiss Precision Diagnostics GmbH | Verbesserte schwangerschaftstestvorrichtung und verbessertes schwangerschaftstestverfahren |
CN110996956A (zh) | 2017-06-05 | 2020-04-10 | 奥布赛瓦股份公司 | 用于治疗子宫内膜异位症的促性腺激素释放激素拮抗剂给药方案 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4282325A (en) * | 1971-05-14 | 1981-08-04 | Syva Company | Enzyme bound corticosteroids |
US4275149A (en) * | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
JPS60260592A (ja) * | 1984-06-08 | 1985-12-23 | Teikoku Hormone Mfg Co Ltd | ステロイド測定用抗原 |
EP0200960A1 (de) * | 1985-05-08 | 1986-11-12 | Abbott Laboratories | Fluoreszenzpolarisationsimmunoassay auf Gesamtöstriol |
US4857652A (en) * | 1986-07-17 | 1989-08-15 | Board Of Governors Of Wayne State University | Chemiluminescent 1,2-dioxetane compounds |
US4962192A (en) * | 1986-07-17 | 1990-10-09 | Board Of Governors Of Wayne State University | Chemiluminescent 1,2-dioxetane compounds |
WO1988000695A1 (en) * | 1986-07-24 | 1988-01-28 | Quest Systems, Inc. | Method of detecting a substance using enzymatically-induced decomposition of dioxetanes |
US4990443A (en) * | 1988-01-25 | 1991-02-05 | Boehringer Mannheim Gmbh | Hapten-protein conjugates and methods of use in immunoassays |
FR2627588A1 (fr) * | 1988-02-24 | 1989-08-25 | Ire Medgenix Sa | Procede de dosage immunologique d'une substance de structure haptenique |
JPH02213766A (ja) * | 1989-02-15 | 1990-08-24 | Mochida Pharmaceut Co Ltd | 免疫測定用試薬および免疫測定器具 |
GB8926407D0 (en) * | 1989-11-22 | 1990-01-10 | Gen Electric Plc | Polymers |
US5342760A (en) * | 1992-06-10 | 1994-08-30 | Abbott Laboratories | Determination of estradiol by competitive immunoassay |
US5395938A (en) * | 1992-08-21 | 1995-03-07 | Nichols Institute Diagnostics | Biotinylated chemiluminescent labels and their conjugates, assays and assay kits |
US5491071A (en) * | 1993-08-03 | 1996-02-13 | Abbott Laboratories | Reagents and methods for the detection and quantification of testosterone in fluid samples |
-
1995
- 1995-03-03 US US08/398,226 patent/US5663054A/en not_active Expired - Fee Related
-
1996
- 1996-02-26 JP JP52689896A patent/JP3640970B2/ja not_active Expired - Fee Related
- 1996-02-26 ES ES96908511T patent/ES2176445T3/es not_active Expired - Lifetime
- 1996-02-26 WO PCT/US1996/002495 patent/WO1996027800A1/en active IP Right Grant
- 1996-02-26 AT AT96908511T patent/ATE216780T1/de not_active IP Right Cessation
- 1996-02-26 EP EP96908511A patent/EP0813684B1/de not_active Expired - Lifetime
- 1996-02-26 DE DE69620876T patent/DE69620876T2/de not_active Expired - Fee Related
- 1996-02-26 CA CA002214085A patent/CA2214085A1/en not_active Abandoned
-
1997
- 1997-04-16 US US08/840,782 patent/US5932431A/en not_active Expired - Lifetime
-
1999
- 1999-06-18 US US09/336,884 patent/US6201141B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5932431A (en) | 1999-08-03 |
JP3640970B2 (ja) | 2005-04-20 |
WO1996027800A1 (en) | 1996-09-12 |
EP0813684B1 (de) | 2002-04-24 |
ATE216780T1 (de) | 2002-05-15 |
DE69620876T2 (de) | 2002-12-12 |
CA2214085A1 (en) | 1996-09-12 |
US5663054A (en) | 1997-09-02 |
EP0813684A1 (de) | 1997-12-29 |
US6201141B1 (en) | 2001-03-13 |
ES2176445T3 (es) | 2002-12-01 |
JPH11501397A (ja) | 1999-02-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69620876D1 (de) | Bestimmung von steroiden durch kompetitiven immunoassay | |
Dressendörfer et al. | Synthesis of a cortisol-biotin conjugate and evaluation as a tracer in an immunoassay for salivary cortisol measurement | |
Leclercq et al. | Abbott monoclonal enzyme immunoassay measurement of estrogen receptors in human breast cancer: a European multicenter study | |
CA2217818A1 (en) | Chemiluminescent immunoassay for antibody detection | |
GB2029011A (en) | The use of a synthetic bifunctional ligand for the immunometric determination of the concentration ratio of two solutes | |
ATE221997T1 (de) | Immunoassays zum nachweis von antiphospholipid- antikörpern | |
Al-Dujaili | Development and validation of a simple and direct ELISA method for the determination of conjugated (glucuronide) and non-conjugated testosterone excretion in urine | |
Nakao | Practical procedure for enzyme immunoassay of progesterone in bovine serum | |
KR960029789A (ko) | 생체내 물질의 면역학적 분석용 키트 및 면역학적 분석 방법 | |
Ito et al. | Simultaneous determination of alpha-fetoprotein, human chorionic gonadotropin and estriol in serum of pregnant women by time-resolved fluoroimmunoassay | |
Oda et al. | Determination of bufalin-like immunoreactivity in serum of humans and rats by time-resolved fluoroimmunoassay for using a monoclonal antibody | |
Kayoko et al. | Enzyme immunoassay of serum testosterone | |
Mares et al. | Synthesis of a novel biotin-estradiol conjugate and its use for the development of a direct, broad range enzyme immunoassay for plasma estradiol | |
JP2669703B2 (ja) | 測定法、用途及び構成部品 | |
Yoshiharu et al. | Fluorescence quenching immunoassay of serum cortisol | |
Ren et al. | Development of a high‐throughput, indirect antibody immobilization format chemiluminescence enzyme immunoassay (CLEIA) for the determination of progesterone in human serum | |
KR880701380A (ko) | 고상 분석 방법 | |
Brun et al. | Enzyme-linked immunosorbent assays for the synthetic steroid gestrinone | |
El Jabri | Enzyme immunoassay for plasma estradiol using a monoclonal antibody | |
DE69725118D1 (en) | Reagentien für tests für mycophenolsäure | |
HUP0100948A2 (hu) | Antitest kompeticiós teszt (AKT) P-glikoprotein és egyéb sejtfelszíni receptorok, pumpák és fehérjék konformáció-változásainak kvalitatív, illetve konformáció-függő kvantitatív kimutatására és annak alkalmazásai | |
Van Weemen et al. | Enzyme-immunoassay of steroids: Possibilities and pitfalls | |
Harwood et al. | Development of enzyme immunoassay for endogenous ouabain-like compound in human plasma | |
Osterman et al. | Enzyme immunoassay of estrogen-like substances in plasma, with polyethylene glycol as precipitant. | |
Kakabakos et al. | Heterogeneous fluoroimmunoassays using fluorescein as label with measurement of the fluorescence signal directly onto the solid-phase |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |