ATE213738T1 - Azaheterocyclische tachykinin rezeptor antagoniste; nk1 und nk2 - Google Patents

Azaheterocyclische tachykinin rezeptor antagoniste; nk1 und nk2

Info

Publication number
ATE213738T1
ATE213738T1 AT96308711T AT96308711T ATE213738T1 AT E213738 T1 ATE213738 T1 AT E213738T1 AT 96308711 T AT96308711 T AT 96308711T AT 96308711 T AT96308711 T AT 96308711T AT E213738 T1 ATE213738 T1 AT E213738T1
Authority
AT
Austria
Prior art keywords
azaheterocyclic
tachykinin receptor
receptor antagonists
receptors
chem
Prior art date
Application number
AT96308711T
Other languages
English (en)
Inventor
Takahide Nishi
Koki Ishibashi
Katsuyoshi Nakajima
Tetsuya Fukazawa
Hitoshi Kurata
Takeshi Yamaguchi
Kazuhiro Ito
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of ATE213738T1 publication Critical patent/ATE213738T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT96308711T 1995-12-01 1996-12-02 Azaheterocyclische tachykinin rezeptor antagoniste; nk1 und nk2 ATE213738T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP31382895 1995-12-01
JP33636995 1995-12-25
JP29686996 1996-11-08

Publications (1)

Publication Number Publication Date
ATE213738T1 true ATE213738T1 (de) 2002-03-15

Family

ID=27338095

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96308711T ATE213738T1 (de) 1995-12-01 1996-12-02 Azaheterocyclische tachykinin rezeptor antagoniste; nk1 und nk2

Country Status (18)

Country Link
US (2) US6159967A (de)
EP (1) EP0776893B1 (de)
CN (1) CN1142932C (de)
AT (1) ATE213738T1 (de)
AU (1) AU719158B2 (de)
CA (1) CA2191815C (de)
CZ (1) CZ288498B6 (de)
DE (1) DE69619479T2 (de)
DK (1) DK0776893T3 (de)
ES (1) ES2170211T3 (de)
HU (1) HU224225B1 (de)
IL (1) IL119729A (de)
MX (1) MX9606082A (de)
NO (1) NO308300B1 (de)
NZ (1) NZ299859A (de)
PT (1) PT776893E (de)
RU (1) RU2135494C1 (de)
TW (1) TW367327B (de)

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FR2824828B1 (fr) * 2001-05-21 2005-05-20 Sanofi Synthelabo Nouveaux derives de piperidinecarboxamide, un procede pour leur preparation et les compositions pharmaceutiques les contenant
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JP2004067673A (ja) * 2002-06-11 2004-03-04 Sankyo Co Ltd 環状チオエーテル類の製造法及びその合成中間体
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Also Published As

Publication number Publication date
IL119729A0 (en) 1997-03-18
HUP9603298A3 (en) 1999-10-28
HU9603298D0 (en) 1997-01-28
NO308300B1 (no) 2000-08-28
CA2191815C (en) 2005-05-10
US6159967A (en) 2000-12-12
HU224225B1 (hu) 2005-06-28
US6448247B1 (en) 2002-09-10
DE69619479D1 (de) 2002-04-04
NZ299859A (en) 1997-11-24
MX9606082A (es) 1998-08-30
RU2135494C1 (ru) 1999-08-27
IL119729A (en) 2001-07-24
ES2170211T3 (es) 2002-08-01
NO965125L (no) 1997-06-02
CZ352196A3 (en) 1997-06-11
PT776893E (pt) 2002-06-28
HUP9603298A2 (hu) 1998-09-28
EP0776893A1 (de) 1997-06-04
CZ288498B6 (en) 2001-06-13
TW367327B (en) 1999-08-21
NO965125D0 (no) 1996-12-02
CA2191815A1 (en) 1997-06-02
DE69619479T2 (de) 2002-10-17
CN1157286A (zh) 1997-08-20
HK1011366A1 (en) 1999-07-09
EP0776893B1 (de) 2002-02-27
AU7406596A (en) 1997-06-05
DK0776893T3 (da) 2002-03-18
AU719158B2 (en) 2000-05-04
CN1142932C (zh) 2004-03-24

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