ATE213159T1 - Pharmazeutische zusammensetzungen mit mirtazapin und einem oder mehreren selektiven serotonin- aufnahme inhibitoren - Google Patents

Pharmazeutische zusammensetzungen mit mirtazapin und einem oder mehreren selektiven serotonin- aufnahme inhibitoren

Info

Publication number
ATE213159T1
ATE213159T1 AT97201853T AT97201853T ATE213159T1 AT E213159 T1 ATE213159 T1 AT E213159T1 AT 97201853 T AT97201853 T AT 97201853T AT 97201853 T AT97201853 T AT 97201853T AT E213159 T1 ATE213159 T1 AT E213159T1
Authority
AT
Austria
Prior art keywords
pharmaceutical compositions
compositions containing
selective serotonin
uptake inhibitors
serotonin uptake
Prior art date
Application number
AT97201853T
Other languages
English (en)
Inventor
Victor Johannes Nickolson
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8224094&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE213159(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE213159T1 publication Critical patent/ATE213159T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97201853T 1996-06-19 1997-06-17 Pharmazeutische zusammensetzungen mit mirtazapin und einem oder mehreren selektiven serotonin- aufnahme inhibitoren ATE213159T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201703 1996-06-19

Publications (1)

Publication Number Publication Date
ATE213159T1 true ATE213159T1 (de) 2002-02-15

Family

ID=8224094

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97201853T ATE213159T1 (de) 1996-06-19 1997-06-17 Pharmazeutische zusammensetzungen mit mirtazapin und einem oder mehreren selektiven serotonin- aufnahme inhibitoren

Country Status (25)

Country Link
US (1) US5977099A (de)
JP (2) JP4925074B2 (de)
KR (1) KR100481254B1 (de)
CN (1) CN1132581C (de)
AR (1) AR007609A1 (de)
AT (1) ATE213159T1 (de)
AU (1) AU727851B2 (de)
BR (1) BR9703624A (de)
CA (1) CA2208199C (de)
CZ (1) CZ290691B6 (de)
DE (1) DE69710390T2 (de)
DK (1) DK0813873T3 (de)
ES (1) ES2172744T3 (de)
HK (1) HK1006081A1 (de)
HU (1) HU225534B1 (de)
ID (1) ID17051A (de)
IL (1) IL121076A (de)
NO (1) NO313177B1 (de)
NZ (1) NZ328113A (de)
PL (1) PL188520B1 (de)
PT (1) PT813873E (de)
RU (1) RU2181287C2 (de)
SG (1) SG60073A1 (de)
TR (1) TR199700522A3 (de)
ZA (1) ZA975335B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL121076A (en) * 1996-06-19 2000-10-31 Akzo Nobel Nv Pharmaceutical combinations comprising mirtazapine and one or more selective serotonin reuptake inhibitors
JP2001522891A (ja) * 1997-11-14 2001-11-20 アクゾ・ノベル・エヌ・ベー 睡眠時無呼吸を治療するためのミルタザピンの使用
US6960577B2 (en) * 1998-05-22 2005-11-01 Eli Lilly And Company Combination therapy for treatment of refractory depression
US6727283B2 (en) 1998-10-13 2004-04-27 Pfizer Inc. Sertraline oral concentrate
US6575147B2 (en) * 1999-02-25 2003-06-10 Go-Tec Internal combustion system adapted for use of a dual fuel composition including acetylene
EP1178805A4 (de) * 1999-04-19 2004-11-24 Teva Pharma Neue synthese und kristallisierung von piperazinringenthaltenden verbindungen
US6545149B2 (en) 1999-04-19 2003-04-08 Teva Pharmaceutical Industries Ltd. Synthesis and crystallization of piperazine ring-containing compounds
US6403657B1 (en) * 1999-10-04 2002-06-11 Martin C. Hinz Comprehensive pharmacologic therapy for treatment of obesity
US6759437B2 (en) * 1999-10-04 2004-07-06 Martin C. Hinz Comprehensive pharmacologic therapy for treatment of obesity including cysteine
RU2268725C2 (ru) * 2000-01-19 2006-01-27 Акцо Нобель Н.В. Комбинация лекарственных препаратов, включающая миртазапин, для лечения депрессии и связанных расстройств
WO2002036113A1 (en) * 2000-11-01 2002-05-10 Respiratorius Ab Composition comprising: serotonin receptor antagonists (5ht-2, 5ht-3) and agonist (5ht-4)
US20030105082A1 (en) * 2001-12-03 2003-06-05 Murphy Greer Marechal Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4
AU2002237847A1 (en) * 2001-02-12 2002-08-28 Akzo Nobel N.V Methods for improving the treatment of major depression by genotyping for the gene for apolipoproteine e4
US6399310B1 (en) 2001-02-12 2002-06-04 Akzo Nobel N.V. Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4
US20090311795A1 (en) * 2002-03-21 2009-12-17 Hinz Martin C Bilateral control of functions traditionally regulated by only serotonin or only dopamine
US20070293571A1 (en) * 2006-06-08 2007-12-20 Hinz Martin C Adminstration of dopa precursors with sources of dopa to effectuate optimal catecholamine neurotransmitter outcomes
MXPA04009123A (es) * 2002-03-21 2005-09-08 C Hinz Martin Tecnologia de optimizacion del segmento del sistema de serotonina y catecolamina.
AR042806A1 (es) * 2002-12-27 2005-07-06 Otsuka Pharma Co Ltd Combinacion de derivados de carboestirilo e inhibidores de la reabsorcion de serotonina para el tratamiento de trastornos del animo
DK1575590T3 (da) * 2002-12-27 2008-02-11 Otsuka Pharma Co Ltd Carbostyrilderivater og serotoningenoptagelsesinhibitorer til behandling af sindsstemningslidelser
CA2516653A1 (en) * 2003-02-21 2004-09-10 Martin C. Hinz Serotonin and catecholamine system segment optimization technology
TW200502222A (en) * 2003-04-02 2005-01-16 Novartis Ag Use of 10-hydroxy-10,11-dihydrocarbamazepine derivatives for the treatment of affective disorders
JP4343948B2 (ja) 2003-04-29 2009-10-14 オレキシジェン・セラピューティクス・インコーポレーテッド 体重減少に影響を及ぼすための組成物
US20050234093A1 (en) * 2003-06-25 2005-10-20 H. Lundbeck A/S Treatment of depression and other affective disorders
US7838029B1 (en) * 2003-07-31 2010-11-23 Watson Laboratories, Inc. Mirtazapine solid dosage forms
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
ES2426915T3 (es) 2003-09-10 2013-10-25 Brentwood Equities Ltd. Diastereoisómeros de 4-ariloxi-3-hidroxipiperidinas
US7713959B2 (en) * 2004-01-13 2010-05-11 Duke University Compositions of an anticonvulsant and mirtazapine to prevent weight gain
TW200538100A (en) * 2004-04-21 2005-12-01 Akzo Nobel Nv Mirtazapine salts
WO2006023702A2 (en) * 2004-08-20 2006-03-02 Cypress Bioscience, Inc. Method for treating sleep related breathing disorders with setiptiline
US20060122127A1 (en) * 2004-11-17 2006-06-08 Cypress Bioscience, Inc. Methods for reducing the side effects associated with mirtzapine treatment
EP1814589B1 (de) * 2004-11-19 2015-04-15 MSD Oss B.V. Arzneistoffkombination enthaltend einen selektiven inhibitor der serotoninwiederaufnahme und einen glucocorticoid rezeptor antagonist zur behandlung von depressionen
CA2630624C (en) 2005-11-22 2013-08-06 Orexigen Therapeutics, Inc. Compositions and methods for increasing insulin sensitivity
US8916195B2 (en) 2006-06-05 2014-12-23 Orexigen Therapeutics, Inc. Sustained release formulation of naltrexone
DK2089005T3 (da) 2006-11-09 2010-07-19 Orexigen Therapeutics Inc Lagdelte farmaceutiske formuleringer omfattende et hurtigt opløsende mellemlag
KR20160072276A (ko) 2006-11-09 2016-06-22 오렉시젠 세러퓨틱스 인크. 단위 용량 팩키지
EP2167096A4 (de) * 2007-06-13 2010-07-14 Cypress Bioscience Inc Verbesserung der verträglichkeit von mirtazapin und eines zweiten wirkstoffes durch ihre kombinierte verwendung
CN101332193B (zh) * 2007-06-29 2012-12-12 杭州民生药业有限公司 一种马来酸氟伏沙明药物组合物的制备方法
CA2725930A1 (en) 2008-05-30 2009-12-30 Orexigen Therapeutics, Inc. Methods for treating visceral fat conditions
WO2010143628A1 (ja) 2009-06-09 2010-12-16 住友重機械工業株式会社 ハイブリッド式ショベル及びその制御方法
US8785453B2 (en) * 2009-11-13 2014-07-22 Green Cross Corporation Arylpiperazine-containing purine derivatives and uses thereof
CN102724878A (zh) 2010-01-11 2012-10-10 奥雷西根治疗公司 在重度抑郁症患者中提供体重减轻疗法的方法
CN102000334B (zh) * 2010-10-15 2012-02-22 北京大学 用于治疗抑郁症的复方制剂
RU2475235C2 (ru) * 2011-03-15 2013-02-20 Общество с ограниченной ответственностью "ЭР ЭНД ДИ ФАРМА" Фармацевтическая композиция для профилактики и лечения депрессивных состояний
JOP20120083B1 (ar) * 2011-04-05 2021-08-17 Otsuka Pharma Co Ltd توليفات تشتمل على بريكس ببرازول أو ملح منه وعقار ثاني للاستخدام في علاج اضطراب cns
EA201492175A1 (ru) 2012-06-06 2015-10-30 Орексиджен Терапьютикс, Инк. Способы лечения избыточного веса и ожирения

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL189199C (nl) * 1975-04-05 1993-02-01 Akzo Nv Werkwijze ter bereiding van farmaceutische preparaten met werking op het centraal zenuwstelsel op basis van benz(aryl)azepinederivaten, de verkregen gevormde farmaceutische preparaten, alsmede werkwijze ter bereiding van de toe te passen benz(aryl)azepinederivaten.
AU8770282A (en) * 1981-08-27 1983-03-03 Shaun R. Coughlin Composition for the treatment of atherosclerosis
US4940585A (en) * 1989-02-17 1990-07-10 Hapworth William E Method for the treatment of nicotine withdrawal syndrome
US5208261A (en) * 1989-12-06 1993-05-04 Akzo N.V. Stabilized solutions of psychotropic agents
EP0431663B1 (de) * 1989-12-06 1994-01-12 Akzo Nobel N.V. Psychotropische Wirkstoffe enthaltende stabilisierte Lösungen
US5512593A (en) * 1993-03-02 1996-04-30 John S. Nagle Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhibitor
IL121076A (en) * 1996-06-19 2000-10-31 Akzo Nobel Nv Pharmaceutical combinations comprising mirtazapine and one or more selective serotonin reuptake inhibitors
TW587938B (en) * 1997-03-27 2004-05-21 Akzo Nobel Nv Pharmaceutical composition for the treatment and/or prophylaxis of psychotic disorder
CN1155410C (zh) * 1997-10-03 2004-06-30 卡里药品公司 治疗尼古丁成瘾的含有尼古丁受体拮抗剂和抗抑郁药或抗焦虑药的组合物

Also Published As

Publication number Publication date
HUP9701068A2 (hu) 1998-08-28
CN1132581C (zh) 2003-12-31
JP4925074B2 (ja) 2012-04-25
RU2181287C2 (ru) 2002-04-20
JPH1067663A (ja) 1998-03-10
SG60073A1 (en) 1999-02-22
CN1173330A (zh) 1998-02-18
DK0813873T3 (da) 2002-05-27
CZ187097A3 (cs) 1998-01-14
IL121076A (en) 2000-10-31
DE69710390T2 (de) 2002-08-14
ZA975335B (en) 1998-01-26
PL188520B1 (pl) 2005-02-28
BR9703624A (pt) 1998-09-01
HUP9701068A3 (en) 2000-07-28
US5977099A (en) 1999-11-02
HU225534B1 (en) 2007-02-28
IL121076A0 (en) 1997-11-20
KR100481254B1 (ko) 2005-09-12
JP2009137970A (ja) 2009-06-25
TR199700522A2 (xx) 1998-01-21
AU2612997A (en) 1998-01-08
ID17051A (id) 1997-12-04
TR199700522A3 (tr) 1998-01-21
CA2208199C (en) 2006-10-24
PT813873E (pt) 2002-06-28
MX9704579A (es) 1998-07-31
AU727851B2 (en) 2001-01-04
ES2172744T3 (es) 2002-10-01
NO972816D0 (no) 1997-06-18
NO972816L (no) 1997-12-22
CA2208199A1 (en) 1997-12-19
HK1006081A1 (en) 1999-02-12
AR007609A1 (es) 1999-11-10
CZ290691B6 (cs) 2002-09-11
NZ328113A (en) 1999-09-29
DE69710390D1 (de) 2002-03-21
KR980000447A (ko) 1998-03-30
PL320628A1 (en) 1997-12-22
HU9701068D0 (en) 1997-08-28
NO313177B1 (no) 2002-08-26

Similar Documents

Publication Publication Date Title
DE69710390D1 (de) Pharmazeutische Zusammensetzungen mit Mirtazapin und einem oder mehreren selektiven Serotonin-Aufnahme Inhibitoren
DE69726015D1 (de) Pharmazeutische zusammensetzung enthaltend koenzym q-10
NO955034L (no) Nye substituerte 1H-imidazoler og farmasöytiske preparater inneholdende disse
IL138028A0 (en) Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical use
DE68925814D1 (de) Hydrogeniertes block-copolymer und dessen zusammensetzung
DE69618587D1 (de) Chinazoline und pharmazeutische zusammensetzungen
DE69634053D1 (de) Oral anzuwendende Arzneizusammensetzung enthaltend 2-Methyl-thienobenzodiazepin
FI954767A (fi) Lipofiilisiä lääkeaineita sisältävä farmaseuttinen koostumus
FI955311A0 (fi) Farmaseuttinen koostumuspohja
BR9506119A (pt) Composição farmacêutica e forma de dosagem farmacêutica unitária
ATE180973T1 (de) Paroxetin enthaltende tabletten und verfahren
NO971811D0 (no) Bicykliske tetrahydropyrazolopyridiner og deres anvendelse som legemidler
HUP9900071A3 (en) Tribenzimidazoles useful as topoisomerase i inhibitors, pharmaceutical compositions containing them and their use
DE59801987D1 (de) Pharmazeutische zusammensetzung enthaltend peptichemio
IS4809A (is) Taxóíð, efnasmíði þeirra og lyfjasamsetning sem inniheldur þau
DE69739855D1 (de) Benzothiophene und denen enthaltende zusammensetzungen
ID18698A (id) Komposisi farmasi
DK0815126T3 (da) Bicykliske tachykinin-antagonister, fremstilling deraf og deres anvendelse i farmaceutiske præparater
DE19681529D2 (de) Pharmazeutische Darreichungsform
ITMI962628A0 (it) Composizione farmaceutica
IT1272935B (it) Composizione farmaceutica contenente n-acetil-cisteina
IS4909A (is) Spíró-píperidín afleiður og notkun þeirra sem lyfjafræðilegra miðla
IT1288113B1 (it) Composizioni farmaceutiche effervescenti contenenti sobrerolo
IT1284509B1 (it) Composizioni farmaceutiche effervescenti contenenti metansolfoanilidi
ID17133A (id) Komposisi farmasi

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee