MXPA04009123A - Tecnologia de optimizacion del segmento del sistema de serotonina y catecolamina. - Google Patents

Tecnologia de optimizacion del segmento del sistema de serotonina y catecolamina.

Info

Publication number
MXPA04009123A
MXPA04009123A MXPA04009123A MXPA04009123A MXPA04009123A MX PA04009123 A MXPA04009123 A MX PA04009123A MX PA04009123 A MXPA04009123 A MX PA04009123A MX PA04009123 A MXPA04009123 A MX PA04009123A MX PA04009123 A MXPA04009123 A MX PA04009123A
Authority
MX
Mexico
Prior art keywords
serotonin
catecholamine
precursor
amino acid
techonology
Prior art date
Application number
MXPA04009123A
Other languages
English (en)
Inventor
C Hinz Martin
Original Assignee
C Hinz Martin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C Hinz Martin filed Critical C Hinz Martin
Publication of MXPA04009123A publication Critical patent/MXPA04009123A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describe un metodo para tratar disfuncion de neurotransmisor en un paciente. El metodo incluye la etapa de administrar un aminoacido precursor de una catecolamina en un intervalo equilibrado y terapeutico eficaz. El precursor de catecolamina preferiblemente es L-dopa, pero de manera alternativa puede ser tirosina, D- L-fenilalanina o un isomero activo del mismo y N-acetil-L-tirosina u otro aminoacido precursor de L-dopa. Tambien se administra un aminoacido precursor de serotonina en un intervalo terapeuticamente eficaz. El precursor de serotonina preferiblemente es 5-HTP, pero de manera alternativa puede ser triptofano. De manera preferible tambien se administra por lo menos un cofactor. Las opciones de cofactor incluyen vitamina B6, vitamina C, calcio, folato y cisteina. Tambien se describe un metodo de administracion periodica y verificacion del paciente.
MXPA04009123A 2002-03-21 2003-03-21 Tecnologia de optimizacion del segmento del sistema de serotonina y catecolamina. MXPA04009123A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36698302P 2002-03-21 2002-03-21
PCT/US2003/008843 WO2003079886A2 (en) 2002-03-21 2003-03-21 Serotonin and catecholamine system segment optimization techonology

Publications (1)

Publication Number Publication Date
MXPA04009123A true MXPA04009123A (es) 2005-09-08

Family

ID=28454829

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04009123A MXPA04009123A (es) 2002-03-21 2003-03-21 Tecnologia de optimizacion del segmento del sistema de serotonina y catecolamina.

Country Status (7)

Country Link
US (3) US20030181509A1 (es)
EP (1) EP1490073A4 (es)
AU (1) AU2003222045A1 (es)
BR (1) BR0308556A (es)
CA (1) CA2479218A1 (es)
MX (1) MXPA04009123A (es)
WO (1) WO2003079886A2 (es)

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Also Published As

Publication number Publication date
BR0308556A (pt) 2005-05-03
US20030181509A1 (en) 2003-09-25
EP1490073A4 (en) 2006-02-01
WO2003079886A3 (en) 2004-02-12
US20060178423A1 (en) 2006-08-10
AU2003222045A1 (en) 2003-10-08
US20080241278A1 (en) 2008-10-02
CA2479218A1 (en) 2003-10-02
AU2003222045A8 (en) 2003-10-08
WO2003079886A2 (en) 2003-10-02
EP1490073A2 (en) 2004-12-29

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