ATE205598T1 - Oberflächenladungsbeschichtung für kapillare elektrophorese - Google Patents

Oberflächenladungsbeschichtung für kapillare elektrophorese

Info

Publication number
ATE205598T1
ATE205598T1 AT91900595T AT91900595T ATE205598T1 AT E205598 T1 ATE205598 T1 AT E205598T1 AT 91900595 T AT91900595 T AT 91900595T AT 91900595 T AT91900595 T AT 91900595T AT E205598 T1 ATE205598 T1 AT E205598T1
Authority
AT
Austria
Prior art keywords
tube
electroosmotic flow
surface charge
capillary electrophoresis
flow rate
Prior art date
Application number
AT91900595T
Other languages
English (en)
Inventor
John E Wiktorowicz
Original Assignee
Pe Corp Ny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pe Corp Ny filed Critical Pe Corp Ny
Application granted granted Critical
Publication of ATE205598T1 publication Critical patent/ATE205598T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44752—Controlling the zeta potential, e.g. by wall coatings
AT91900595T 1989-11-06 1990-11-06 Oberflächenladungsbeschichtung für kapillare elektrophorese ATE205598T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/432,061 US5015350A (en) 1989-11-06 1989-11-06 Flow-rate-controlled surface-charge coating for capillary electrophoresis
PCT/US1990/006435 WO1991006851A1 (en) 1989-11-06 1990-11-06 Flow-rate controlled surface charge coating for capillary electrophoresis

Publications (1)

Publication Number Publication Date
ATE205598T1 true ATE205598T1 (de) 2001-09-15

Family

ID=23714589

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91900595T ATE205598T1 (de) 1989-11-06 1990-11-06 Oberflächenladungsbeschichtung für kapillare elektrophorese

Country Status (6)

Country Link
US (1) US5015350A (de)
EP (1) EP0500784B1 (de)
JP (1) JP3044481B2 (de)
AT (1) ATE205598T1 (de)
DE (1) DE69033795T2 (de)
WO (1) WO1991006851A1 (de)

Families Citing this family (45)

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US5089106A (en) * 1986-10-21 1992-02-18 Northeastern University High performance capillary gel electrophoresis
US5122248A (en) * 1990-05-18 1992-06-16 Northeastern University Pulsed field capillary electrophoresis
US5332481A (en) 1991-01-29 1994-07-26 Beckman Instruments, Inc. Capillary electrophoresis using replaceable gels
US5212000A (en) * 1991-03-11 1993-05-18 The Dow Chemical Company Method for providing an inner-skinned functionalized coating on the lumen-defining surface of a hollow tube
US5098539A (en) * 1991-04-19 1992-03-24 Beckman Instruments, Inc. Gel-containing microcapillary column
US5213669A (en) * 1992-01-31 1993-05-25 Beckman Instruments, Inc. Capillary column containing a dynamically cross-linked composition and method of use
JPH07503542A (ja) * 1992-01-31 1995-04-13 ベックマン　インスツルメンツ　インコーポレーテッド 除去できる分離ゲル組成物を含有する毛管カラム及びその使用方法
US5296116A (en) * 1992-06-17 1994-03-22 Beckman Instruments, Inc. Capillary electrophoresis using time-varying field strength
US5302264A (en) * 1992-09-02 1994-04-12 Scientronix, Inc. Capillary eletrophoresis method and apparatus
US5286356A (en) * 1993-01-21 1994-02-15 Millipore Corporation Method for sample analysis using capillary electrophoresis
US5415747A (en) * 1993-08-16 1995-05-16 Hewlett-Packard Company Capillary electrophoresis using zwitterion-coated capillary tubes
US5342492A (en) * 1993-09-01 1994-08-30 The Board Of Trustees Of The Leland Stanford Junior University System for electrokinetic separation and detection where detection is performed at other than separation electric field
US5462646A (en) * 1993-09-29 1995-10-31 Beckman Instruments, Inc. Coated capillary columns and electrophoretic separation methods for their use
WO1995016910A1 (en) * 1993-12-17 1995-06-22 Perkin-Elmer Corporation Uncharged polymers for separation of biomolecules by capillary electrophoresis
US6358385B1 (en) * 1993-12-17 2002-03-19 The Perkin-Elmer Corporation Polymers for separation of biomolecules by capillary electrophoresis
US5423966A (en) * 1994-01-25 1995-06-13 Perkin-Elmer Corporation On line ion contaminant removal apparatus and method for capillary electrophoresis
US5573651A (en) * 1995-04-17 1996-11-12 The Dow Chemical Company Apparatus and method for flow injection analysis
US5578179A (en) 1995-07-12 1996-11-26 The Perkin-Elmer Corporation Method and silicate composition for conditioning silica surfaces
US5942443A (en) 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
SE9602638D0 (sv) * 1996-07-03 1996-07-03 Pharmacia Biotech Ab An improved method for the capillary electrophoresis of nucleic acids, proteins and low molecular charged compounds
US6110343A (en) * 1996-10-04 2000-08-29 Lockheed Martin Energy Research Corporation Material transport method and apparatus
ATE370406T1 (de) * 1996-12-03 2007-09-15 Eisai R&D Man Co Ltd Kapillare mit beschichteter innenwand
US7033474B1 (en) 1997-04-25 2006-04-25 Caliper Life Sciences, Inc. Microfluidic devices incorporating improved channel geometries
CA2287409C (en) * 1997-04-25 2003-06-03 Caliper Technologies Corporation Microfluidic devices incorporating improved channel geometries
US5976336A (en) 1997-04-25 1999-11-02 Caliper Technologies Corp. Microfluidic devices incorporating improved channel geometries
US6224830B1 (en) * 1998-01-30 2001-05-01 The Governors Of The University Of Alberta Absorbance cell for microfluid devices
US6537432B1 (en) 1998-02-24 2003-03-25 Target Discovery, Inc. Protein separation via multidimensional electrophoresis
US6706161B1 (en) * 1998-06-10 2004-03-16 Agilent Technologies, Inc. Methods and compositions for modifying the surface of a polymeric substrate
EP2278320B1 (de) * 1999-02-02 2018-07-18 Caliper Life Sciences, Inc. Verfahren und Vorrichtungen zur Charakterisierung von Proteinen
US6306273B1 (en) 1999-04-13 2001-10-23 Aclara Biosciences, Inc. Methods and compositions for conducting processes in microfluidic devices
US6764817B1 (en) 1999-04-20 2004-07-20 Target Discovery, Inc. Methods for conducting metabolic analyses
US6818112B2 (en) * 1999-04-20 2004-11-16 Target Discovery, Inc. Protein separation via multidimensional electrophoresis
US6706162B1 (en) 2000-09-25 2004-03-16 Applera Corporation High speed, high resolution compositions, methods, and kits for capillary electrophoresis
US6974528B2 (en) * 2001-07-24 2005-12-13 Biomics, Inc. High performance wide bore electrophoresis
US20050165558A1 (en) * 2002-02-26 2005-07-28 Becker Robert G. Sequence detection system calculator
US7381317B2 (en) * 2002-08-12 2008-06-03 Beckman Coulter, Inc. Methods and compositions for capillary electrophoresis (CE)
US20040115830A1 (en) * 2002-09-25 2004-06-17 Igor Touzov Components for nano-scale Reactor
US20050025741A1 (en) * 2003-05-15 2005-02-03 Lau Aldrich N.K. Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis
JP4450368B2 (ja) 2004-03-04 2010-04-14 独立行政法人産業技術総合研究所 マイクロ流路チップの製造方法、マイクロ流路チップ、そのマイクロ流路チップを用いる生体分子の分離方法、およびそのマイクロ流路チップを有する電気泳動装置
US20070014699A1 (en) 2005-06-23 2007-01-18 Beckman Coulter, Inc, Methods and apparatus for improving the sensitivity of capillary zone electrophoresis
CN100389323C (zh) * 2005-07-22 2008-05-21 中国科学院上海有机化学研究所 毛细管电泳酶微反应器的制备方法和用途
CN101501484B (zh) 2006-09-04 2012-12-26 独立行政法人产业技术综合研究所 通过毛细管电泳法分析试样的方法
WO2008029685A1 (fr) 2006-09-04 2008-03-13 National Institute Of Advanced Industrial Science And Technology Procédé pour analyse d'échantillon par électrophorèse capillaire
WO2013074314A1 (en) * 2011-11-16 2013-05-23 Luna Innovations Incorporated Method and apparatus for ofdr-based electrophoresis
CN103018310A (zh) * 2012-12-14 2013-04-03 凯晶生物科技(苏州)有限公司 用于实现多次进样的毛细管芯片电泳结构及其实现方法

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Publication number Priority date Publication date Assignee Title
US3909380A (en) * 1974-07-19 1975-09-30 Komline Sanderson Eng Corp Reference pattern zeta potential measurement apparatus and method therefor
FR2580812B1 (fr) * 1985-04-22 1988-04-22 Univ Caen Procede pour attenuer ou supprimer le phenomene d'electro-osmose dans une cellule d'electrophorese et cellule d'electrophorese ainsi obtenue
US4680201A (en) * 1985-10-30 1987-07-14 Stellan Hjerten Coating for electrophoresis tube
US4690749A (en) * 1985-12-16 1987-09-01 Universities Space Research Association Polymer-coated surfaces to control surface zeta potential
US4865707A (en) * 1986-10-21 1989-09-12 Northeastern University Capillary gel electrophoresis columns
US4865706A (en) * 1986-10-21 1989-09-12 Northeastern University High performance microcapillary gel electrophoresis

Also Published As

Publication number Publication date
JPH05503989A (ja) 1993-06-24
DE69033795T2 (de) 2002-05-23
EP0500784B1 (de) 2001-09-12
EP0500784A1 (de) 1992-09-02
JP3044481B2 (ja) 2000-05-22
US5015350A (en) 1991-05-14
DE69033795D1 (de) 2001-10-18
EP0500784A4 (en) 1993-03-17
WO1991006851A1 (en) 1991-05-16

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