ATE203748T1 - Indazolcarboxamide - Google Patents

Indazolcarboxamide

Info

Publication number
ATE203748T1
ATE203748T1 AT96301682T AT96301682T ATE203748T1 AT E203748 T1 ATE203748 T1 AT E203748T1 AT 96301682 T AT96301682 T AT 96301682T AT 96301682 T AT96301682 T AT 96301682T AT E203748 T1 ATE203748 T1 AT E203748T1
Authority
AT
Austria
Prior art keywords
alkyl
phenyl
naphthyl
amino
substituted
Prior art date
Application number
AT96301682T
Other languages
English (en)
Inventor
John Thomas Catlow
Marlene Lois Cohen
Michael John Martinelli
John Mehnert Schaus
Steven Phillip Swanson
Dennis Charles Thompson
Thomas Michael Wilson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/485,956 external-priority patent/US5654320A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE203748T1 publication Critical patent/ATE203748T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
AT96301682T 1995-03-16 1996-03-12 Indazolcarboxamide ATE203748T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40511995A 1995-03-16 1995-03-16
US08/485,956 US5654320A (en) 1995-03-16 1995-06-07 Indazolecarboxamides

Publications (1)

Publication Number Publication Date
ATE203748T1 true ATE203748T1 (de) 2001-08-15

Family

ID=27018928

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96301682T ATE203748T1 (de) 1995-03-16 1996-03-12 Indazolcarboxamide

Country Status (23)

Country Link
US (2) US5817676A (de)
EP (1) EP0732333B1 (de)
JP (1) JPH11502230A (de)
CN (1) CN1112923C (de)
AT (1) ATE203748T1 (de)
AU (1) AU700842B2 (de)
BR (1) BR9608223A (de)
CA (1) CA2215359A1 (de)
DE (1) DE69614164T2 (de)
DK (1) DK0732333T3 (de)
EA (1) EA000699B1 (de)
ES (1) ES2159345T3 (de)
GR (1) GR3037029T3 (de)
HU (1) HU223973B1 (de)
IL (1) IL117438A (de)
NO (1) NO312833B1 (de)
NZ (1) NZ315971A (de)
PL (1) PL183867B1 (de)
PT (1) PT732333E (de)
RO (1) RO119617B1 (de)
SK (1) SK283924B6 (de)
TR (1) TR199700956T1 (de)
WO (1) WO1996033713A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1291569B1 (it) * 1997-04-15 1999-01-11 Angelini Ricerche Spa Indazolammidi come agenti serotoninergici
US6069152A (en) * 1997-10-07 2000-05-30 Eli Lilly And Company 5-HT4 agonists and antagonists
US5914405A (en) * 1997-10-07 1999-06-22 Eli Lilly And Company Process for preparing 3-substituted indazoles
HU228179B1 (en) * 1998-08-21 2013-01-28 Novartis Ag Pharmaceutical, oral compositions containing 5-ht4 agonists or antagonists as active agent
EP1112270B1 (de) 1998-09-10 2007-03-21 F. Hoffmann-La Roche Ag Dihydrobenzodioxincarbonsäureamid- und ketonderivate als 5-ht4-rezeptorantagonisten
AU2001270304A1 (en) 2000-07-07 2002-01-21 The Administrators Of The Tulane Educational Fund Methods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor
KR20030027010A (ko) * 2000-08-07 2003-04-03 라보라뜨와르 글락소스미스클라인 심방 세동 예방 또는 치료용 의약의 제조에서의 5ｈｔ4수용체 길항제의 용도
EP1321142A1 (de) * 2001-12-21 2003-06-25 Novartis AG Feste orale Zubereitung mit Tegaserod
ATE401072T1 (de) 2002-02-12 2008-08-15 Organon Nv 1-arylsulfonyl-3-substituierte indol und indolinederivate verwendbar zur behandlung von erkrankungen des zentralnervensystem
ITMI20030287A1 (it) 2003-02-18 2004-08-19 Acraf Indazolammidi dotate di attivita' analgesica metodo, per
ITMI20031468A1 (it) * 2003-07-18 2005-01-19 Acraf Farmaco ativo nel dolore neuropatico
ITMI20031467A1 (it) * 2003-07-18 2005-01-19 Acraf Farmaco attivo nel dolore neuropatico
SE0401969D0 (sv) * 2004-08-02 2004-08-02 Astrazeneca Ab Piperidine derivatives
EP1910340B1 (de) * 2005-07-22 2009-11-18 Pfizer, Inc. Indazolcarbonsäureamidderivate als agonisten des 5ht4-rezeptors
WO2009106980A2 (en) * 2008-02-29 2009-09-03 Pfizer Inc. Indazole derivatives
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145215A (en) * 1961-12-19 1964-08-18 Sterling Drug Inc Indazole derivatives
JP2795460B2 (ja) * 1988-06-20 1998-09-10 協和醗酵工業株式会社 ピラゾロアクリドン誘導体
NZ230068A (en) * 1988-07-29 1991-07-26 Dainippon Pharmaceutical Co Indazole-3-carboxylic acid esters and amides of diaza compounds having 6,7, or 8 ring members: preparatory processes and pharmaceutical compositions
EP0410509A1 (de) * 1989-07-25 1991-01-30 Duphar International Research B.V Substituierte 1H-Indazol-3-carboxamide
HU211081B (en) * 1990-12-18 1995-10-30 Sandoz Ag Process for producing indole derivatives as serotonin antagonists and pharmaceutical compositions containing the same
JPH06510283A (ja) * 1991-08-20 1994-11-17 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー ５−ｈｔ４レセプター拮抗薬
US5552398A (en) * 1991-09-12 1996-09-03 Smithkline Beecham P.L.C. Azabicyclic compounds as 5-HT4 receptor antagonists
JPH07507290A (ja) * 1992-05-23 1995-08-10 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー 不安症の治療のための医薬
WO1994000113A2 (en) * 1992-06-27 1994-01-06 Smithkline Beecham Plc Medicaments containing 5-ht4 receptor antagonists
MX9305947A (es) * 1992-09-29 1994-06-30 Smithkline Beecham Plc Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
TW251287B (de) * 1993-04-30 1995-07-11 Nissei Co Ltd
GB9310582D0 (en) * 1993-05-22 1993-07-07 Smithkline Beecham Plc Pharmaceuticals

Also Published As

Publication number Publication date
EA199700242A1 (ru) 1998-04-30
RO119617B1 (ro) 2005-01-28
GR3037029T3 (en) 2002-01-31
EA000699B1 (ru) 2000-02-28
US5817676A (en) 1998-10-06
BR9608223A (pt) 1998-12-29
WO1996033713A1 (en) 1996-10-31
EP0732333A1 (de) 1996-09-18
CN1112923C (zh) 2003-07-02
NO974221D0 (no) 1997-09-12
US5798367A (en) 1998-08-25
JPH11502230A (ja) 1999-02-23
PT732333E (pt) 2001-11-30
AU6894896A (en) 1996-11-18
HUP9801386A2 (hu) 1999-06-28
PL322362A1 (en) 1998-01-19
NZ315971A (en) 1999-01-28
CN1183041A (zh) 1998-05-27
DE69614164T2 (de) 2002-04-25
EP0732333B1 (de) 2001-08-01
DE69614164D1 (de) 2001-09-06
DK0732333T3 (da) 2001-10-08
HU223973B1 (hu) 2005-03-29
TR199700956T1 (xx) 1998-02-21
AU700842B2 (en) 1999-01-14
CA2215359A1 (en) 1996-10-31
ES2159345T3 (es) 2001-10-01
HUP9801386A3 (en) 2000-03-28
SK283924B6 (sk) 2004-05-04
NO974221L (no) 1997-10-27
MX9706967A (es) 1997-11-29
IL117438A (en) 2001-12-23
NO312833B1 (no) 2002-07-08
IL117438A0 (en) 1996-07-23
PL183867B1 (pl) 2002-07-31
SK124297A3 (en) 1998-02-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee