ATE199393T1 - Von analogen der choleratoxin-untereinheit abgeleitete rekombinante dna - Google Patents

Von analogen der choleratoxin-untereinheit abgeleitete rekombinante dna

Info

Publication number
ATE199393T1
ATE199393T1 AT92915195T AT92915195T ATE199393T1 AT E199393 T1 ATE199393 T1 AT E199393T1 AT 92915195 T AT92915195 T AT 92915195T AT 92915195 T AT92915195 T AT 92915195T AT E199393 T1 ATE199393 T1 AT E199393T1
Authority
AT
Austria
Prior art keywords
recombinant dna
dna derived
choleratoxin
analogue
subunit analogue
Prior art date
Application number
AT92915195T
Other languages
English (en)
Inventor
W Neal Burnette
Harvey R Kaslow
Original Assignee
Amgen Inc
Univ Southern California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc, Univ Southern California filed Critical Amgen Inc
Application granted granted Critical
Publication of ATE199393T1 publication Critical patent/ATE199393T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/28Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/832Drug, bio-affecting and body treating compositions involving bacterial toxin that has modified amino acid sequence
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/909Vibrio

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT92915195T 1991-05-02 1992-05-04 Von analogen der choleratoxin-untereinheit abgeleitete rekombinante dna ATE199393T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69473391A 1991-05-02 1991-05-02
PCT/US1992/003703 WO1992019265A1 (en) 1991-05-02 1992-05-04 Recombinant dna-derived cholera toxin subunit analogs

Publications (1)

Publication Number Publication Date
ATE199393T1 true ATE199393T1 (de) 2001-03-15

Family

ID=24790064

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92915195T ATE199393T1 (de) 1991-05-02 1992-05-04 Von analogen der choleratoxin-untereinheit abgeleitete rekombinante dna

Country Status (18)

Country Link
US (2) US5874287A (de)
EP (1) EP0584284B9 (de)
JP (1) JP3242106B2 (de)
KR (1) KR100249888B1 (de)
CN (1) CN1067679A (de)
AR (1) AR248167A1 (de)
AT (1) ATE199393T1 (de)
AU (1) AU665013B2 (de)
CA (1) CA2102105A1 (de)
DE (1) DE69231708T2 (de)
DK (1) DK0584284T3 (de)
ES (1) ES2156110T3 (de)
GR (1) GR3035724T3 (de)
IL (1) IL101715A (de)
MX (1) MX9202030A (de)
NZ (1) NZ242539A (de)
WO (1) WO1992019265A1 (de)
ZA (1) ZA923162B (de)

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US4666837A (en) * 1982-05-24 1987-05-19 Smithkline-Rit DNA sequences, recombinant DNA molecules and processes for producing the A and B subunits of cholera toxin and preparations containing so-obtained subunit or subunits
US4935364A (en) * 1983-03-04 1990-06-19 Swiss Serum And Vaccine Institute Berne Method of isolating restriction fragment deletions in vibrio cholerae and products thereof
US4882278A (en) * 1983-04-29 1989-11-21 President And Fellows Of Harvard College Non-toxinogenic vibrio cholerae mutants

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AU2293092A (en) 1992-12-21
EP0584284A4 (de) 1995-03-15
EP0584284B1 (de) 2001-02-28
JP3242106B2 (ja) 2001-12-25
KR100249888B1 (ko) 2000-04-01
CN1067679A (zh) 1993-01-06
DE69231708T2 (de) 2001-07-05
AR248167A1 (es) 1995-06-30
IL101715A0 (en) 1992-12-30
DK0584284T3 (da) 2001-06-18
IL101715A (en) 2005-06-19
US5770203A (en) 1998-06-23
US5874287A (en) 1999-02-23
EP0584284A1 (de) 1994-03-02
JPH06507551A (ja) 1994-09-01
GR3035724T3 (en) 2001-07-31
MX9202030A (es) 1993-02-01
EP0584284B9 (de) 2002-11-13
WO1992019265A1 (en) 1992-11-12
AU665013B2 (en) 1995-12-14
CA2102105A1 (en) 1992-11-03
ZA923162B (en) 1993-04-28
NZ242539A (en) 1993-11-25
ES2156110T3 (es) 2001-06-16
DE69231708D1 (de) 2001-04-05

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