ATE192152T1 - Piperidinderivate mit paf antagonistischer wirkung - Google Patents

Piperidinderivate mit paf antagonistischer wirkung

Info

Publication number
ATE192152T1
ATE192152T1 AT95932668T AT95932668T ATE192152T1 AT E192152 T1 ATE192152 T1 AT E192152T1 AT 95932668 T AT95932668 T AT 95932668T AT 95932668 T AT95932668 T AT 95932668T AT E192152 T1 ATE192152 T1 AT E192152T1
Authority
AT
Austria
Prior art keywords
pct
antagonistic effect
piperidine derivatives
paf
paf antagonistic
Prior art date
Application number
AT95932668T
Other languages
English (en)
Inventor
Elena Carceller
Pere J Jimenez
Nuria Recasens
Jordi Salas
Carmen Almansa
Javier Bartroli
Original Assignee
Uriach & Cia Sa J
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uriach & Cia Sa J filed Critical Uriach & Cia Sa J
Application granted granted Critical
Publication of ATE192152T1 publication Critical patent/ATE192152T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT95932668T 1994-11-07 1995-09-05 Piperidinderivate mit paf antagonistischer wirkung ATE192152T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES09402291A ES2087038B1 (es) 1994-11-07 1994-11-07 Nuevas piperidinas con actividad antagonista del paf.
PCT/EP1995/003487 WO1996014317A1 (en) 1994-11-07 1995-09-05 Novel piperidine derivatives with paf antagonist activity

Publications (1)

Publication Number Publication Date
ATE192152T1 true ATE192152T1 (de) 2000-05-15

Family

ID=8287905

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95932668T ATE192152T1 (de) 1994-11-07 1995-09-05 Piperidinderivate mit paf antagonistischer wirkung

Country Status (13)

Country Link
US (1) US5705504A (de)
EP (1) EP0738269B1 (de)
JP (1) JP4018137B2 (de)
KR (1) KR100514201B1 (de)
AT (1) ATE192152T1 (de)
AU (1) AU3563695A (de)
DE (1) DE69516503T2 (de)
DK (1) DK0738269T5 (de)
ES (2) ES2087038B1 (de)
GR (1) GR3033528T3 (de)
NO (1) NO306345B1 (de)
PT (1) PT738269E (de)
WO (1) WO1996014317A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4115522B2 (ja) * 1995-09-08 2008-07-09 ホタ． ウリアチ イ コンパニア ソシエダッド アノニマ 新規な５−アミノサリチル酸のアゾ誘導体
ES2165803B1 (es) * 2000-04-10 2003-09-16 Uriach & Cia Sa J Nueva sal de un derivado azo del acido 5-aminosalicilico
GB0013060D0 (en) * 2000-05-31 2000-07-19 Astrazeneca Ab Chemical compounds
JP2004516237A (ja) 2000-06-21 2004-06-03 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー ケモカイン受容体活性調節剤としてのピペリジンアミド類
PT1311269E (pt) * 2000-08-04 2012-05-10 Dmi Biosciences Inc Método de utilização de dicetopiperazinas e composição que contém as mesmas
GB0021670D0 (en) 2000-09-04 2000-10-18 Astrazeneca Ab Chemical compounds
GB0117899D0 (en) 2001-07-23 2001-09-12 Astrazeneca Ab Chemical compounds
CA3050734A1 (en) 2003-05-15 2004-12-02 Ampio Pharmaceuticals, Inc. Treatment of t-cell mediated diseases
FR2860514A1 (fr) * 2003-10-03 2005-04-08 Sanofi Synthelabo Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique
WO2007101270A1 (en) * 2006-03-02 2007-09-07 Incyte Corporation MODULATORS OF 11-β HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME
US7678785B2 (en) 2006-07-24 2010-03-16 Ucb Pharma S.A. Substituted aniline derivatives
KR100737397B1 (ko) 2007-01-31 2007-07-09 한국교세라정공(주) 밀링 커터
WO2009146320A1 (en) 2008-05-27 2009-12-03 Dmi Life Sciences, Inc. Therapeutic methods and compounds
FR2962649B1 (fr) 2010-07-19 2025-10-24 Conservatoire Nat Arts Et Metiers Traitement d'une pathologie liee a un effet excessif du tnf par un compose de benzene sulfonamide
GB201101517D0 (en) * 2011-01-28 2011-03-16 Proximagen Ltd Receptor antagonists
JP6203734B2 (ja) 2011-10-10 2017-09-27 アンピオ ファーマシューティカルズ，インコーポレイテッド 変形性関節疾患の治療
PH12014500686A1 (en) 2011-10-10 2020-12-18 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
HK1198812A1 (en) 2011-10-28 2015-06-12 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
MX2015010937A (es) 2013-03-15 2015-10-29 Ampio Pharmaceuticals Inc Composiciones para la movilizacion, autodireccion, expansion y diferenciacion de celulas madre y metodos para usar las mismas.
EP3183240A4 (de) 2014-08-18 2018-06-27 Ampio Pharmaceuticals, Inc. Behandlung von gelenkerkrankungen
HK1246669A1 (zh) 2015-06-22 2018-09-14 Ampio Pharmaceuticals, Inc. 人血清白蛋白低分子量组分在疾病治疗中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0029707B1 (de) * 1979-11-21 1984-02-01 Kyowa Hakko Kogyo Co., Ltd Piperidinderivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
IL85700A0 (en) * 1987-03-24 1988-08-31 Takeda Chemical Industries Ltd 1,4-disubstituted piperazine compounds,their production and use
EP0441226A1 (de) * 1990-01-29 1991-08-14 J. URIACH & CIA. S.A. (Cyanomethyl)-Pyridine verwendbar als PAF Antagonisten
GB9102997D0 (en) * 1991-02-13 1991-03-27 Pfizer Ltd Therapeutic agents
ES2036926B1 (es) * 1991-08-08 1994-01-16 Uriach & Cia Sa J "procedimiento para la obtencion de derivados de la (2-alquil-3-piridil)metilpiperazina".
US5268376A (en) * 1991-09-04 1993-12-07 Minnesota Mining And Manufacturing Company 1-substituted 1H-imidazo[4,5-c]quinolin-4-amines
US5283242A (en) * 1991-10-24 1994-02-01 American Home Products Corporation Substituted benzimidazoles and quinazolines as antihypertensives

Also Published As

Publication number Publication date
JPH09507862A (ja) 1997-08-12
EP0738269B1 (de) 2000-04-26
ES2087038A1 (es) 1996-07-01
DE69516503T2 (de) 2001-03-15
ES2087038B1 (es) 1997-03-16
MX9602559A (es) 1997-07-31
GR3033528T3 (en) 2000-09-29
NO962855L (no) 1996-07-05
PT738269E (pt) 2000-08-31
AU3563695A (en) 1996-05-31
KR100514201B1 (ko) 2005-12-29
WO1996014317A1 (en) 1996-05-17
JP4018137B2 (ja) 2007-12-05
ES2147616T3 (es) 2000-09-16
NO962855D0 (no) 1996-07-05
DK0738269T5 (da) 2000-12-18
US5705504A (en) 1998-01-06
NO306345B1 (no) 1999-10-25
DK0738269T3 (da) 2000-08-28
DE69516503D1 (de) 2000-05-31
EP0738269A1 (de) 1996-10-23

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee