ATE156841T1 - Cs-peptide von p. falciparum als allgemeines t- zellen-epitop - Google Patents

Cs-peptide von p. falciparum als allgemeines t- zellen-epitop

Info

Publication number
ATE156841T1
ATE156841T1 AT89108618T AT89108618T ATE156841T1 AT E156841 T1 ATE156841 T1 AT E156841T1 AT 89108618 T AT89108618 T AT 89108618T AT 89108618 T AT89108618 T AT 89108618T AT E156841 T1 ATE156841 T1 AT E156841T1
Authority
AT
Austria
Prior art keywords
falciparum
peptide
cell epitope
mhc
immunogenic compositions
Prior art date
Application number
AT89108618T
Other languages
English (en)
Inventor
Francesco Dr Sinigaglia
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE156841T1 publication Critical patent/ATE156841T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00—Other engines
    • F02B75/02—Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/806—Antigenic peptides or proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT89108618T 1988-05-24 1989-05-12 Cs-peptide von p. falciparum als allgemeines t- zellen-epitop ATE156841T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888812214A GB8812214D0 (en) 1988-05-24 1988-05-24 Use of peptide from circumsporozoite protein of p falciparum as universally recognized t-cell epitope

Publications (1)

Publication Number Publication Date
ATE156841T1 true ATE156841T1 (de) 1997-08-15

Family

ID=10637401

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89108618T ATE156841T1 (de) 1988-05-24 1989-05-12 Cs-peptide von p. falciparum als allgemeines t- zellen-epitop

Country Status (11)

Country Link
US (1) US5114713A (de)
EP (1) EP0343460B1 (de)
JP (1) JP2761402B2 (de)
AT (1) ATE156841T1 (de)
AU (1) AU627459B2 (de)
CA (1) CA1340472C (de)
DE (1) DE68928251T2 (de)
DK (1) DK250589A (de)
GB (1) GB8812214D0 (de)
NZ (1) NZ229146A (de)
ZA (1) ZA893702B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2031197A1 (en) * 1989-04-12 1990-10-13 James P. Tam Dendritic polymer of multiple antigen peptide system useful as anti-malarial vaccine
GB8924438D0 (en) * 1989-10-31 1989-12-20 Hoffmann La Roche Vaccine composition
US5547669A (en) * 1989-11-03 1996-08-20 Immulogic Pharma Corp Recombinant peptides comprising T cell epitopes of the cat allergen, Fel d I
IT1241395B (it) * 1990-04-02 1994-01-10 Eniricerche Spa Composti immunogenici,il procedimento per la loro sintesi e loro impiego per la preparazione di vaccini antimalaria
CH683101A5 (de) * 1990-09-18 1994-01-14 Biotech Australia Pty Ltd T-Zellen-Epitope.
DE4102042A1 (de) * 1991-01-24 1992-07-30 Bayer Ag Substituierte aminosaeureamid-derivate deren herstellung und verwendung als fungizide
DK0614465T3 (da) * 1991-11-16 1999-09-27 Smithkline Beecham Biolog Hybridprotein mellem CS fra Plasmodium og HBsAg
US6169171B1 (en) 1992-02-27 2001-01-02 Smithkline Beecham Biologicals (S.A.) Hybrid protein between CS from plasmodium and HBSAG
US5928902A (en) * 1992-02-27 1999-07-27 Smithkline Beecham Biologicals (S.A.) Hybrid protein between CS from plasmodium and HBsAg
GB9215780D0 (en) * 1992-07-24 1992-09-09 Univ London Pharmacy Peptide compounds
BR9306984A (pt) 1992-08-27 1999-01-12 Deakin Res Ltd Análogo de antígeno de peptídeo de um antígeno de peptídeo nativo vacina anticorpo processo para vacinar um hospedeiro necessitando deste tratamento estojo diagnóstico processos para preparar um análogo de um antiígeno de um antígeno de peptídeo nativo para preparar uma vacina para analisar uma amostra para um antígeno de peptídeo nativo e para analisar uma amostra para um anticorpo
US5674977A (en) * 1993-02-05 1997-10-07 The Ontario Cancer Institute Branched synthetic peptide conjugate
JP3795914B2 (ja) * 1993-04-27 2006-07-12 ユナイテッド・バイオメディカル・インコーポレイテッド ワクチン用免疫原性ｌｈｒｈペプチド構築体および合成普遍免疫刺激器
US5759551A (en) * 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
WO1995000540A1 (en) * 1993-06-18 1995-01-05 Robert Webber Synthetic carrier and immunogen
DK96493D0 (da) * 1993-08-26 1993-08-26 Mouritsen Og Elsner Aps Fremgangsmaade til at inducere antistofresponser mod selvproteiner og autovaccine fremstillet ved fremgangsmaaden
AU707083B2 (en) * 1993-08-26 1999-07-01 Bavarian Nordic Inc. Inducing antibody response against self-proteins with the aid of foreign T-cell epitopes
US20050049197A1 (en) * 1993-09-14 2005-03-03 Epimmune Inc. Induction of immune response against desired determinants
US6413935B1 (en) * 1993-09-14 2002-07-02 Epimmune Inc. Induction of immune response against desired determinants
ES2318848T3 (es) * 1993-09-14 2009-05-01 Pharmexa Inc. Peptidos que se unen a pan dr para potenciar la respuesta inmunitaria.
GB9422294D0 (en) * 1994-11-04 1994-12-21 Peptide Therapeutics Ltd Peptides for anti-allergy treatment
US5773003A (en) * 1995-03-31 1998-06-30 Immulogic, Inc. Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same
PT814843E (pt) * 1995-03-31 2004-04-30 Xenova Res Ltd Conjugados de hapteno-transportador para utilizacao na terapia de abuso de drogas
US6410022B1 (en) 1995-05-01 2002-06-25 Avant Immunotherapeutics, Inc. Modulation of cholesteryl ester transfer protein (CETP) activity
EP0831881B1 (de) 1995-06-06 2003-03-12 Avant Immunotherapeutics, Inc. Cetp zur erhöhung des hdl-cholesterol-gehalts
US6284533B1 (en) 1996-05-01 2001-09-04 Avant Immunotherapeutics, Inc. Plasmid-based vaccine for treating atherosclerosis
US6846808B1 (en) 1996-05-01 2005-01-25 Avant Immunotherapeutics, Inc. Plasmid-based vaccine for treating atherosclerosis
WO1998031382A1 (en) * 1997-01-21 1998-07-23 New York University Universal t-cell epitopes for anti-malarial vaccines
EP0884327B1 (de) 1997-06-11 2001-03-14 The School Of Pharmacy, University Of London Dendritische, lysinhaltige Polypeptide zur gezielten Arzneimittelabreichung
US20030232055A1 (en) * 2000-07-31 2003-12-18 Ruslan Medzhitov Innate immune system-directed vaccines
US20030175287A1 (en) * 2001-01-03 2003-09-18 Yale University Innate immune system-directed vaccines
US7491690B2 (en) * 2001-11-14 2009-02-17 Northwestern University Self-assembly and mineralization of peptide-amphiphile nanofibers
US7371719B2 (en) * 2002-02-15 2008-05-13 Northwestern University Self-assembly of peptide-amphiphile nanofibers under physiological conditions
US7554021B2 (en) * 2002-11-12 2009-06-30 Northwestern University Composition and method for self-assembly and mineralization of peptide amphiphiles
ATE541580T1 (de) 2003-12-05 2012-02-15 Univ Northwestern Selbst anordnende peptid-amphiphile und relevante verfahren für die abgabe von wachstumsfaktor
WO2005070959A2 (en) * 2004-01-23 2005-08-04 Vievax Corp. Compositions comprising immune response altering agents and methods of use
KR20070100948A (ko) * 2005-01-21 2007-10-15 노오쓰웨스턴 유니버시티 세포의 캡슐화 방법 및 조성물
CA2598251A1 (en) * 2005-03-04 2006-09-14 Northwestern University Angiogenic heparin binding peptide amphiphiles
US8076295B2 (en) * 2007-04-17 2011-12-13 Nanotope, Inc. Peptide amphiphiles having improved solubility and methods of using same
JP5697447B2 (ja) * 2007-08-15 2015-04-08 サーカッシア リミテッド アレルゲンに対する脱感作のためのペプチド
US7642125B2 (en) * 2007-09-14 2010-01-05 Macronix International Co., Ltd. Phase change memory cell in via array with self-aligned, self-converged bottom electrode and method for manufacturing
WO2010086743A2 (en) 2009-02-02 2010-08-05 Chrontech Pharma Ab Compositions and methods that enhance an immune response
JP2012523463A (ja) * 2009-04-13 2012-10-04 ノースウエスタン ユニバーシティ 軟骨再生のための新規なペプチドベースの足場およびその使用方法
US9169304B2 (en) 2012-05-01 2015-10-27 Pfenex Inc. Process for purifying recombinant Plasmodium falciparum circumsporozoite protein
WO2014186409A1 (en) 2013-05-15 2014-11-20 Chrontech Pharma Ab Immunogenic compositions for inhibiting hepatitis d virus

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ213303A (en) * 1984-09-12 1988-09-29 Univ New York Plasmodium protein, dna sequence and vaccine
US4826957A (en) * 1985-07-12 1989-05-02 New York University Immunogenic recombinant yeast expression product and method for purifying it
US4886782A (en) * 1987-02-26 1989-12-12 The United States Of America As Represented By The Department Of Health And Human Services Malarial immunogen
US5028425A (en) * 1988-07-07 1991-07-02 The United States Of America As Represented By The Department Of Health And Human Services Synthetic vaccine against P. falciparum malaria
GB8819209D0 (en) * 1988-08-12 1988-09-14 Research Corp Ltd Polypeptide & dna encoding same

Also Published As

Publication number Publication date
DE68928251D1 (de) 1997-09-18
AU3504689A (en) 1989-11-30
AU627459B2 (en) 1992-08-27
EP0343460A2 (de) 1989-11-29
DE68928251T2 (de) 1998-03-12
JP2761402B2 (ja) 1998-06-04
US5114713A (en) 1992-05-19
EP0343460A3 (de) 1991-07-31
CA1340472C (en) 1999-03-30
NZ229146A (en) 1994-09-27
JPH0242099A (ja) 1990-02-13
EP0343460B1 (de) 1997-08-13
ZA893702B (en) 1990-02-28
DK250589D0 (da) 1989-05-23
GB8812214D0 (en) 1988-06-29
DK250589A (da) 1989-11-25

Similar Documents

Publication Publication Date Title
ATE156841T1 (de) Cs-peptide von p. falciparum als allgemeines t- zellen-epitop
TR200403064T2 (tr) Tüberkülozun teşhisi ve immünoterapi yolu ile önlenmesine mahsus yöntemler ve bileşikler.
DE69529219T2 (de) Helicobacter proteine und impstoffe
BR9708387A (pt) Processo para vacinação de um mamìfero a um antìgeno selecionado, células patogênica e hospedeira, composição de vacina, ácido nucleico, e, opsonina engenheirada.
DE69233772D1 (de) T-zell epitopen von den wichtigsten allergene von dermatophagoides (hausmilbe)
ATE486887T1 (de) Trägerprotein eines polyepitops
ES2074950A1 (es) Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
DK0427347T3 (da) Syntetiske peptider, der kan anvendes som universelle bærere til fremstilling af immunogene konjugater, og anvendelse deraf til udvikling af syntetiske vacciner
BR9910973A (pt) Vacina
HUP0101464A2 (hu) Mutáns rekombináns allergének
BR0314373A (pt) Produto imunogênico estável para a indução de anticorpos contra uma ou várias proteìnas antigênicas em um indivìduo, composições farmacêutica, imunogênica e de vacina e processo de preparação de um produto imunogênico
ATE413191T1 (de) Verwendung of interleukin-1 mutein als impfstoffadjuvans
BR0308860A (pt) Fator viii modificado
EA199900627A1 (ru) Универсальные т-клеточные эпитопы, используемые для получения антималярийных вакцин
DE69018926D1 (de) Vakzine gegen Bordetella.
DE69031351D1 (de) Zubereitungen und behandlungen von pneumonia in tieren
BR0207015A (pt) Eritropoientina modificada (epo) com imunogenicidade reduzida
BR0207014A (pt) Antagonista de receptor de interleucina-1 modificada (il-1ra) com imunogenicidade reduzida.
SE9604296D0 (sv) New pharmaceutical formulation of polypeptides
FI933210A0 (fi) Avirulent vaccin mot rabies
Skjødt et al. Isolation and characterization of chicken and turkey beta2-microglobulin
HUP0100130A2 (hu) Rekombináns Mycoplasma hyopneumoniae vakcina
PT99923A (pt) Processo para a preparacao de proteinas hibridas de plasmodium falciparum que contem sequencias dos antigenios da malaria hrpii e serp e de composicoes farmaceuticas que contem estas proteinas
Good et al. T-cell antigenic sites of the malaria circumsporozoite protein
AR012896A1 (es) Polipeptido flge de helicobacter pylori, composicion de vacuna, uso de dicho polipeptido para la fabricacion de composiciones, metodo de diagnostico invitro, y kit de diagnostico para la deteccion de la infeccion por helicobacter pylori

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee