PT99923A - Processo para a preparacao de proteinas hibridas de plasmodium falciparum que contem sequencias dos antigenios da malaria hrpii e serp e de composicoes farmaceuticas que contem estas proteinas - Google Patents
Processo para a preparacao de proteinas hibridas de plasmodium falciparum que contem sequencias dos antigenios da malaria hrpii e serp e de composicoes farmaceuticas que contem estas proteinasInfo
- Publication number
- PT99923A PT99923A PT99923A PT9992391A PT99923A PT 99923 A PT99923 A PT 99923A PT 99923 A PT99923 A PT 99923A PT 9992391 A PT9992391 A PT 9992391A PT 99923 A PT99923 A PT 99923A
- Authority
- PT
- Portugal
- Prior art keywords
- proteins
- hrpii
- serp
- malaria
- amino acids
- Prior art date
Links
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 201000004792 malaria Diseases 0.000 title abstract 3
- 241000223960 Plasmodium falciparum Species 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001413 amino acids Chemical class 0.000 abstract 4
- QEVHRUUCFGRFIF-UHFFFAOYSA-N 6,18-dimethoxy-17-[oxo-(3,4,5-trimethoxyphenyl)methoxy]-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylic acid methyl ester Chemical compound C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(C(=O)OC)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 QEVHRUUCFGRFIF-UHFFFAOYSA-N 0.000 abstract 2
- 101100533283 Dictyostelium discoideum serp gene Proteins 0.000 abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000001681 protective effect Effects 0.000 abstract 2
- 101710203310 Apical membrane antigen 1 Proteins 0.000 abstract 1
- 241000282693 Cercopithecidae Species 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000011081 inoculation Methods 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4041836A DE4041836A1 (de) | 1990-12-24 | 1990-12-24 | Protektive plasmodium falciparum hybridproteine, die teilsequenzen der malaria-antigene hrpii und serp enthalten, ihre herstellung und verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT99923A true PT99923A (pt) | 1992-12-31 |
| PT99923B PT99923B (pt) | 1999-06-30 |
Family
ID=6421479
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99923A PT99923B (pt) | 1990-12-24 | 1991-12-23 | Processo para a preparacao de proteinas hibridas de plasmodium falciparum que contem sequencias dos antigenios da malaria hrpii e serp e de composicoes farmaceuticas que contem estas proteinas |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5395614A (pt) |
| EP (1) | EP0492500B1 (pt) |
| JP (1) | JPH06121688A (pt) |
| KR (1) | KR920012116A (pt) |
| AT (1) | ATE136586T1 (pt) |
| AU (1) | AU660437B2 (pt) |
| CA (1) | CA2057761A1 (pt) |
| DE (2) | DE4041836A1 (pt) |
| DK (1) | DK0492500T3 (pt) |
| ES (1) | ES2085947T3 (pt) |
| GR (1) | GR3019825T3 (pt) |
| IE (1) | IE80429B1 (pt) |
| PT (1) | PT99923B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5928902A (en) * | 1992-02-27 | 1999-07-27 | Smithkline Beecham Biologicals (S.A.) | Hybrid protein between CS from plasmodium and HBsAg |
| US6254869B1 (en) * | 1996-03-27 | 2001-07-03 | The Regents Of The University Of California | Cryptopain vaccines, antibodies, proteins, peptides, DNA and RNA for prophylaxis, treatment and diagnosis and for detection of cryptosporidium species |
| BR9812945A (pt) * | 1997-10-20 | 2000-08-08 | Genzyme Transgenics Corp | Sequências de ácido nucléico modificadas e processos para aumentar os nìveis de mrna e expressão de sistemas celulares |
| ATE442440T1 (de) * | 2001-01-24 | 2009-09-15 | Univ Osaka Res Found | Malaria-plasmodium antigen-polypeptid se36, verfahren zu seiner reinigung und impfstoff und diagnose unter verwendung des so erhaltenen antigens |
| CN100385004C (zh) * | 2002-03-01 | 2008-04-30 | 宝生物工程株式会社 | 冷休克诱导的异源多肽的表达和生产 |
| US8556843B2 (en) * | 2008-02-02 | 2013-10-15 | AccelDx | Blood purification method and apparatus for the treatment of malaria |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4859465A (en) * | 1984-04-20 | 1989-08-22 | The Regents Of The University Of California | Vaccine capable of eliciting multivalent antibodies |
| CA1302805C (en) * | 1986-05-15 | 1992-06-09 | Thomas Alan Taylor | Liquid film coating of iron-based metals |
| EP0254862A1 (en) * | 1986-06-26 | 1988-02-03 | BEHRINGWERKE Aktiengesellschaft | Vaccines against protozoan parasites |
| US5130416A (en) * | 1986-08-13 | 1992-07-14 | The United States Of America As Represented By The Department Of Health And Human Services | Recombinant DNA clone containing a genomic fragment of PfHRP-II gene from plasmodium falciparum |
| WO1988002757A1 (en) * | 1986-10-17 | 1988-04-21 | Saramane Pty. Ltd.; | Hybrid proteins or polypeptides |
| US4957738A (en) * | 1987-01-14 | 1990-09-18 | Patarroyo Manuel E | Protein copolymer malaria vaccine |
| DE3741057A1 (de) * | 1987-03-18 | 1988-09-29 | Behringwerke Ag | Klonierung von malaria-spezifischen dna-sequenzen:isolierung des gens fuer das 140 kd protein |
| DE3737238A1 (de) * | 1987-11-03 | 1989-05-18 | Behringwerke Ag | Rekombinantes histidinreiches protein (37 kd antigen) von plasmodium falciparum, seine herstellung und verwendung |
| DE3831351A1 (de) * | 1987-12-30 | 1989-07-13 | Behringwerke Ag | Malaria-spezifische dna-sequenzen, ihre expressionsprodukte und deren verwendung |
| WO1990001549A2 (en) * | 1988-08-12 | 1990-02-22 | Trustees Of Dartmouth College | Gene encoding protein antigens of plasmodium falciparum |
-
1990
- 1990-12-24 DE DE4041836A patent/DE4041836A1/de not_active Withdrawn
-
1991
- 1991-12-20 AT AT91121936T patent/ATE136586T1/de active
- 1991-12-20 DE DE59107665T patent/DE59107665D1/de not_active Expired - Fee Related
- 1991-12-20 DK DK91121936.8T patent/DK0492500T3/da active
- 1991-12-20 AU AU89894/91A patent/AU660437B2/en not_active Ceased
- 1991-12-20 EP EP91121936A patent/EP0492500B1/de not_active Expired - Lifetime
- 1991-12-20 CA CA002057761A patent/CA2057761A1/en not_active Abandoned
- 1991-12-20 ES ES91121936T patent/ES2085947T3/es not_active Expired - Lifetime
- 1991-12-23 IE IE455191A patent/IE80429B1/en not_active IP Right Cessation
- 1991-12-23 KR KR1019910023919A patent/KR920012116A/ko not_active Application Discontinuation
- 1991-12-23 PT PT99923A patent/PT99923B/pt not_active IP Right Cessation
- 1991-12-24 JP JP3356233A patent/JPH06121688A/ja active Pending
-
1993
- 1993-11-16 US US08/152,922 patent/US5395614A/en not_active Expired - Fee Related
-
1996
- 1996-05-03 GR GR960401198T patent/GR3019825T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5395614A (en) | 1995-03-07 |
| DE59107665D1 (de) | 1996-05-15 |
| CA2057761A1 (en) | 1992-06-25 |
| AU660437B2 (en) | 1995-06-29 |
| GR3019825T3 (en) | 1996-08-31 |
| PT99923B (pt) | 1999-06-30 |
| EP0492500B1 (de) | 1996-04-10 |
| IE914551A1 (en) | 1992-07-01 |
| DK0492500T3 (da) | 1996-08-12 |
| EP0492500A3 (en) | 1993-02-10 |
| DE4041836A1 (de) | 1992-06-25 |
| ATE136586T1 (de) | 1996-04-15 |
| IE80429B1 (en) | 1998-07-01 |
| KR920012116A (ko) | 1992-07-25 |
| ES2085947T3 (es) | 1996-06-16 |
| JPH06121688A (ja) | 1994-05-06 |
| AU8989491A (en) | 1992-06-25 |
| EP0492500A2 (de) | 1992-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19920814 |
|
| FG3A | Patent granted, date of granting |
Effective date: 19990304 |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20000930 |