ES2091159A1 - Antigeno recombinante, rsm14, procedente de schistosoma mansoni, su obtencion y utilizacion. - Google Patents

Antigeno recombinante, rsm14, procedente de schistosoma mansoni, su obtencion y utilizacion.

Info

Publication number
ES2091159A1
ES2091159A1 ES09401198A ES9401198A ES2091159A1 ES 2091159 A1 ES2091159 A1 ES 2091159A1 ES 09401198 A ES09401198 A ES 09401198A ES 9401198 A ES9401198 A ES 9401198A ES 2091159 A1 ES2091159 A1 ES 2091159A1
Authority
ES
Spain
Prior art keywords
fatty acid
binding protein
acid binding
vaccine against
schistosoma mansoni
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES09401198A
Other languages
English (en)
Other versions
ES2091159B1 (es
Inventor
Miriam Tendler
Naftale Katz
Andrew John Simpson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fundacao Oswaldo Cruz
Original Assignee
Fundacao Oswaldo Cruz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacao Oswaldo Cruz filed Critical Fundacao Oswaldo Cruz
Publication of ES2091159A1 publication Critical patent/ES2091159A1/es
Application granted granted Critical
Publication of ES2091159B1 publication Critical patent/ES2091159B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C07K14/4354—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A61P33/12—Schistosomicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

ANTIGENO RECOMBINANTE, RSM14, PROCEDENTE DE CVASCHISTOSOMA MANSONI, SU OBTENCION Y UTILIZACION. EL ANTIGENO RECOMBINANTE RSM14 ES UNA PROTEINA DE FUSION QUE COMPRENDE UNA CADENA POLIPEPTIDICA DERIVADA DE UN BACTERIOFAGO UNIDA A LA CADENA POLIPEPTIDICA DE LA PROTEINA SM14 NATIVA DE CVASCHISTOSOMA MANSONI POR UN ENLACE PEPTIDICO. EL ANTIGENO PUEDE OBTENERSE POR EXPRESION DE UN MICROORGANISMO TRANSFORMADO Y PUEDE SER UTILIZADO COMO VACUNA CONTRA LAS ENFERMEDADES CAUSADAS POR LAS INFECCIONES HELMINTICAS DE HUMANOS Y ANIMALES, EN PARTICULAR, LAS CAUSADAS POR ESPECIES DE CVASCHISTOSOMA O FASCIOLA, ASI COMO REACTIVO PARA LA DIAGNOSIS DE ESQUISTOSOMIASIS Y FASCIOLIASIS.
ES09401198A 1993-12-16 1994-06-01 Antigeno recombinante, rsm14, procedente de schistosoma mansoni, su obtencion y utilizacion. Expired - Fee Related ES2091159B1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BR9305075A BR9305075A (pt) 1993-12-16 1993-12-16 Antígeno para conferir imunidade protetora contra infecções helmínticas em humanos e animais,e processo de vacinação para aplicação na imunoprofilaxia de doenças helmintológicas de interesse veterinário e médico

Publications (2)

Publication Number Publication Date
ES2091159A1 true ES2091159A1 (es) 1996-10-16
ES2091159B1 ES2091159B1 (es) 1997-05-01

Family

ID=39496068

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09401198A Expired - Fee Related ES2091159B1 (es) 1993-12-16 1994-06-01 Antigeno recombinante, rsm14, procedente de schistosoma mansoni, su obtencion y utilizacion.

Country Status (10)

Country Link
US (1) US5730984A (es)
JP (1) JP4087908B2 (es)
AU (2) AU684496B2 (es)
BR (1) BR9305075A (es)
DE (1) DE4419264B4 (es)
ES (1) ES2091159B1 (es)
FR (1) FR2714065B1 (es)
GB (2) GB9410856D0 (es)
IT (1) IT1269879B (es)
NZ (2) NZ260649A (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TR200202078T2 (tr) * 1999-03-12 2002-11-21 University Of Massachusetts Lipoglikan bileşimleri ve parazit enfeksiyonlarını tedavi etme metotları
WO2002094228A1 (en) * 2001-05-23 2002-11-28 David Follansbee Prevention and treatment of allergies by helminthic regulation of ige
BRPI0303266B8 (pt) * 2003-01-31 2021-05-25 Fundacao Oswaldo Cruz proteína recombinante sm14, composição imunogênica, e,kit de diagnóstico.
US20110158998A1 (en) * 2005-08-03 2011-06-30 The Council Of The Queensland Institute Of Medical Research Helminth antigen and immunotherapy
KR101245004B1 (ko) * 2010-10-14 2013-03-19 원광대학교산학협력단 주혈흡충증 진단에 유용한 합성 주혈흡충 특이항원 및 이를 포함하는 주혈흡충증의 검출을 위한 진단 키트
BR102021012953A2 (pt) 2021-06-29 2023-01-10 Fabp Biotech Desenvolvimento Em Biotecnologia Ltda. Composição de vacina veterinária contra helmintos, método para tratamento e prevenção de infecção causada por helmintos e uso

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990002563A1 (en) * 1988-09-07 1990-03-22 Medical Research Council Antigens of schistosoma mansoni
US5051254A (en) * 1988-09-30 1991-09-24 The Johns Hopkins University Immunoprophylactic polypeptides for schistosomiasis
WO1993023542A1 (en) * 1992-05-08 1993-11-25 The Biotechnology And Biological Sciences Research Recombinant dna molecules encoding aminopeptidase enzymes and their use in the preparation of vaccines against helminth infections

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4396600A (en) * 1980-12-18 1983-08-02 Gus Gallucci Adult schistosome worm-derived antigenic substance and method of obtaining same
US4656033A (en) * 1985-06-05 1987-04-07 The United States Of America As Represented By The Department Of Health And Human Services Isolated, soluble immunogen against Schistosoma mansoni and a method of vaccination employing same
US5219566A (en) * 1988-09-30 1993-06-15 The Johns Hopkins University Immunoprophylactic polypeptides for schistosomiasis
IL100783A0 (en) * 1992-01-28 1992-09-06 Yeda Res & Dev Vaccine against schistosomiasis
GB9322808D0 (en) * 1993-11-05 1993-12-22 Agricultural & Food Res Vaccines
DE19960225B4 (de) * 1999-12-14 2007-03-01 Max Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Kristallines, in der asymmetrischen Einheit mindestens eine an der Katalyse beteiligte (Sub)-Domaine eines humanen m-Calpains aufweisendes Polypeptid, Verfahren zur Identifizierung von Verbindungen unter dessen Verwendung, Verfahren zu dessen Kristallisation und Verfahren zur Darstellung einer 3-dimensionalen Struktur dieses Peptids

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990002563A1 (en) * 1988-09-07 1990-03-22 Medical Research Council Antigens of schistosoma mansoni
US5051254A (en) * 1988-09-30 1991-09-24 The Johns Hopkins University Immunoprophylactic polypeptides for schistosomiasis
WO1993023542A1 (en) * 1992-05-08 1993-11-25 The Biotechnology And Biological Sciences Research Recombinant dna molecules encoding aminopeptidase enzymes and their use in the preparation of vaccines against helminth infections

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MOSER, D. et al. "A 14-kDa Schistosoma mansoni Polypeptide Is Homologous to a Gene Family of Fatty Acid Binding Proteins". THE JOURNAL OF BIOLOGICAL CHEMISTRY. 5 de Mayo, 1991. Vol. 266, N‘ 13, pßginas 8447-8454 * Todo el documento * *

Also Published As

Publication number Publication date
GB2285626A (en) 1995-07-19
NZ260649A (en) 1997-05-26
US5730984A (en) 1998-03-24
BR9305075A (pt) 1995-08-08
IT1269879B (it) 1997-04-15
GB9425479D0 (en) 1995-02-15
FR2714065B1 (fr) 1998-08-07
AU6341794A (en) 1995-06-29
JP4087908B2 (ja) 2008-05-21
DE4419264A1 (de) 1995-06-22
DE4419264B4 (de) 2010-06-10
FR2714065A1 (fr) 1995-06-23
ITMI941134A1 (it) 1995-12-01
GB9410856D0 (en) 1994-07-20
ES2091159B1 (es) 1997-05-01
GB2285626B (en) 1998-04-15
AU1133195A (en) 1996-08-01
AU684496B2 (en) 1997-12-18
NZ314432A (en) 1997-11-24
JPH07196689A (ja) 1995-08-01
ITMI941134A0 (it) 1994-06-01

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