ATE152179T1 - Analytischer marker für krebs, besonders für bösartigen brustkrebs - Google Patents

Analytischer marker für krebs, besonders für bösartigen brustkrebs

Info

Publication number
ATE152179T1
ATE152179T1 AT92901155T AT92901155T ATE152179T1 AT E152179 T1 ATE152179 T1 AT E152179T1 AT 92901155 T AT92901155 T AT 92901155T AT 92901155 T AT92901155 T AT 92901155T AT E152179 T1 ATE152179 T1 AT E152179T1
Authority
AT
Austria
Prior art keywords
cancer
marker
breast cancer
malignant breast
especially malignant
Prior art date
Application number
AT92901155T
Other languages
English (en)
Inventor
Paul Basset
Jean-Pierre Bellocq
Pierre Chambon
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Application granted granted Critical
Publication of ATE152179T1 publication Critical patent/ATE152179T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6489—Metalloendopeptidases (3.4.24)
    • C12N9/6491—Matrix metalloproteases [MMP's], e.g. interstitial collagenase (3.4.24.7); Stromelysins (3.4.24.17; 3.2.1.22); Matrilysin (3.4.24.23)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Display Devices Of Pinball Game Machines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT92901155T 1990-11-21 1991-11-21 Analytischer marker für krebs, besonders für bösartigen brustkrebs ATE152179T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9025326A GB2250993B (en) 1990-11-21 1990-11-21 Stromelysin-3 and its application in the diagnosis and treatment of malignant breast cancer

Publications (1)

Publication Number Publication Date
ATE152179T1 true ATE152179T1 (de) 1997-05-15

Family

ID=10685753

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92901155T ATE152179T1 (de) 1990-11-21 1991-11-21 Analytischer marker für krebs, besonders für bösartigen brustkrebs

Country Status (16)

Country Link
US (1) US5236844A (de)
EP (1) EP0513316B1 (de)
JP (1) JP3516448B2 (de)
AT (1) ATE152179T1 (de)
CA (1) CA2073860A1 (de)
DE (1) DE69125824T2 (de)
DK (1) DK0513316T3 (de)
ES (1) ES2101079T3 (de)
GB (1) GB2250993B (de)
GR (1) GR3023560T3 (de)
HU (1) HU215165B (de)
IE (1) IE914056A1 (de)
NZ (2) NZ260705A (de)
PT (1) PT99562B (de)
WO (1) WO1992009701A1 (de)
ZA (1) ZA919219B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994012645A2 (en) * 1992-11-25 1994-06-09 University Of Pittsburgh Of The Commonwealth System Of Higher Education cDNA CLONE FOR HUMAN INDUCIBLE NITRIC OXYDE SYNTHASE AND PROCESS FOR PREPARING SAME
AU7401394A (en) * 1993-07-20 1995-02-20 University Of Massachusetts Medical Center In vivo nucleic acid hybridization method
DE69412466T2 (de) * 1993-11-30 1999-04-29 Fuji Yakuhin Kogyo K.K., Takaoka, Toyama Neue metalloprotease und kodierende dna dafür
US6825024B1 (en) 1993-11-30 2004-11-30 Fuji Yakuhin Kogyo Kabushiki Kaisha Metalloproteinase and encoding DNA therefor
JPH07303482A (ja) 1993-11-30 1995-11-21 Fuji Yakuhin Kogyo Kk 新規なメタロプロテアーゼおよびそれをコードするｄｎａ
US5710001A (en) * 1994-08-12 1998-01-20 Myriad Genetics, Inc. 17q-linked breast and ovarian cancer susceptibility gene
US5709999A (en) * 1994-08-12 1998-01-20 Myriad Genetics Inc. Linked breast and ovarian cancer susceptibility gene
US5753441A (en) * 1994-08-12 1998-05-19 Myriad Genetics, Inc. 170-linked breast and ovarian cancer susceptibility gene
US5747282A (en) * 1994-08-12 1998-05-05 Myraid Genetics, Inc. 17Q-linked breast and ovarian cancer susceptibility gene
US5763415A (en) * 1995-08-03 1998-06-09 John Hopkins University School Of Medicine Destruction of the epithelium of an exocrine gland in the prophylactic and therapeutic treatment of cancer
AU6883296A (en) * 1995-09-05 1997-03-27 Celltech Therapeutics Limited Dna sequences coding for a human metalloproteinase and variants thereof
US5905027A (en) * 1995-12-27 1999-05-18 Uab Research Foundation Method of diagnosing and treating gliomas
AU2406497A (en) * 1996-04-25 1997-11-12 Takeda Chemical Industries Ltd. Matrix metalloprotease
US20050202499A1 (en) * 1996-10-31 2005-09-15 Billing-Medel Patricia A. Reagents and methods useful for detecting diseases of the breast
US20050153373A1 (en) * 1996-10-31 2005-07-14 Billing-Medel Patricia A. Reagents and methods useful for detecting diseases of the breast
US20030165971A1 (en) * 1996-10-31 2003-09-04 Billing-Medel Patricia A. Reagents and methods useful for detecting diseases of the breast
DE69737788T2 (de) * 1996-10-31 2008-03-13 Abbott Laboratories, Abbott Park Reagenzien und methoden zum nachweis von erkrankungen der brust
EP0960214A4 (de) * 1996-12-06 2004-08-04 Urocor Inc Diagnose des Krankheitszustandesan HAnd von mRNA-Profilen
WO1998040475A1 (en) * 1997-03-11 1998-09-17 Abbott Laboratories Human matrix metalloprotease gene, proteins encoded therefrom and methods of using same
WO1998041238A2 (en) * 1997-03-18 1998-09-24 Ortho-Mcneil Pharmaceutical, Inc. Methods and kits for treating and diagnosing leiomyomas
US6190857B1 (en) 1997-03-24 2001-02-20 Urocor, Inc. Diagnosis of disease state using MRNA profiles in peripheral leukocytes
US7332270B1 (en) 1997-03-24 2008-02-19 Urocor, Inc. Diagnosis of disease state using mRNA profiles in peripheral leukocytes
US20040072210A1 (en) * 1997-07-07 2004-04-15 Billing-Medel Patricia A. Reagents and methods useful for detecting diseases of the breast
WO1999002714A1 (en) * 1997-07-07 1999-01-21 Abbott Laboratories Reagents and methods useful for detecting diseases of the breast
EP1032689A1 (de) * 1997-11-17 2000-09-06 Abbott Laboratories Reagenzien und methoden zum nachweis von krankheiten der brust
US5972615A (en) 1998-01-21 1999-10-26 Urocor, Inc. Biomarkers and targets for diagnosis, prognosis and management of prostate disease
US6600057B2 (en) 2000-12-29 2003-07-29 Kimberly-Clark Worldwide, Inc. Matrix metalloproteinase inhibitors
US7041787B2 (en) * 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases
US20040219551A1 (en) * 2001-07-09 2004-11-04 Petersen Ole William Epsti1, a novel gene induced by epithelial-stromal interaction in human breast cancer
US20030119073A1 (en) * 2001-12-21 2003-06-26 Stephen Quirk Sensors and methods of detection for proteinase enzymes
DE10217254A1 (de) * 2002-04-15 2003-10-23 Proteosys Ag Verwendung von Substanzen zur Behandlung von Tumoren
US20060088899A1 (en) * 2002-05-31 2006-04-27 Alvarez Vernon L Combination chemotherapy with chlorotoxin
US20050193432A1 (en) * 2003-11-18 2005-09-01 Whitehead Institute For Biomedical Research Xenograft model of functional normal and malignant human breast tissues in rodents and methods thereof
US7667001B1 (en) * 2004-01-27 2010-02-23 Compugen Ltd. Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer
US7569662B2 (en) * 2004-01-27 2009-08-04 Compugen Ltd Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer
US20090191543A1 (en) * 2005-05-27 2009-07-30 Theregents Of The University Of California Identification of rac1b as a marker and mediator of metalloproteinase-induced malignancy
CA2724384A1 (en) 2008-05-15 2009-11-19 Transmolecular, Inc. Treatment of metastatic tumors
DK2531206T3 (en) 2010-02-04 2017-09-11 Morphotek Inc CHLOROTOXIN POLYPEPTIDES AND CONJUGATES AND USE THEREOF
KR101972173B1 (ko) 2010-05-11 2019-04-24 프레드 헛친슨 켄서 리서치 센터 클로로톡신 변이체, 접합체, 및 이의 사용 방법
KR101313184B1 (ko) * 2010-06-24 2013-09-30 한국표준과학연구원 질병 지표 검출 키트 및 질병 지표 검출 방법
CA2913029A1 (en) 2012-12-10 2014-06-19 Fred Hutchinson Cancer Research Center Lipocalin fusion partners
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
WO2017181149A1 (en) 2016-04-15 2017-10-19 Blaze Bioscience, Inc. Methods of treating breast cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63503514A (ja) * 1986-06-17 1988-12-22 セルテク・リミテツド タンパク質の製法

Also Published As

Publication number Publication date
ZA919219B (en) 1992-10-28
HUT65373A (en) 1994-05-02
IE914056A1 (en) 1992-06-03
DE69125824D1 (de) 1997-05-28
WO1992009701A1 (fr) 1992-06-11
DK0513316T3 (da) 1997-05-20
HU9202368D0 (en) 1992-10-28
NZ260705A (en) 1997-05-26
GB2250993A (en) 1992-06-24
PT99562A (pt) 1992-10-30
GR3023560T3 (en) 1997-08-29
GB9025326D0 (en) 1991-01-02
HU215165B (hu) 1998-10-28
JPH05505530A (ja) 1993-08-19
US5236844A (en) 1993-08-17
PT99562B (pt) 1999-04-30
AU9089691A (en) 1992-06-25
EP0513316B1 (de) 1997-04-23
EP0513316A1 (de) 1992-11-19
GB2250993B (en) 1995-02-15
AU646914B2 (en) 1994-03-10
CA2073860A1 (en) 1992-05-22
NZ240688A (en) 1994-09-27
JP3516448B2 (ja) 2004-04-05
DE69125824T2 (de) 1997-08-07
ES2101079T3 (es) 1997-07-01

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee