ATE147758T1 - Von synthetischer dns abgeleitete rekombinante hiv-1-antigene - Google Patents
Von synthetischer dns abgeleitete rekombinante hiv-1-antigeneInfo
- Publication number
- ATE147758T1 ATE147758T1 AT89121513T AT89121513T ATE147758T1 AT E147758 T1 ATE147758 T1 AT E147758T1 AT 89121513 T AT89121513 T AT 89121513T AT 89121513 T AT89121513 T AT 89121513T AT E147758 T1 ATE147758 T1 AT E147758T1
- Authority
- AT
- Austria
- Prior art keywords
- hiv
- proteins
- synthetic dna
- antigens derived
- recombinant hiv
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Virology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27530988A | 1988-11-23 | 1988-11-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE147758T1 true ATE147758T1 (de) | 1997-02-15 |
Family
ID=23051743
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89121513T ATE147758T1 (de) | 1988-11-23 | 1989-11-21 | Von synthetischer dns abgeleitete rekombinante hiv-1-antigene |
AT95114545T ATE286978T1 (de) | 1988-11-23 | 1989-11-21 | Rekombinante hiv-2 antigenen, abgeleitete aus synthetischen dns |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT95114545T ATE286978T1 (de) | 1988-11-23 | 1989-11-21 | Rekombinante hiv-2 antigenen, abgeleitete aus synthetischen dns |
Country Status (9)
Country | Link |
---|---|
US (3) | US5859193A (de) |
EP (2) | EP0370458B1 (de) |
JP (2) | JP3073752B2 (de) |
AT (2) | ATE147758T1 (de) |
AU (1) | AU628108B2 (de) |
CA (1) | CA2003383A1 (de) |
DE (2) | DE68927665T2 (de) |
ES (2) | ES2238071T3 (de) |
GR (1) | GR3022850T3 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5939074A (en) * | 1986-12-30 | 1999-08-17 | The United States Of America As Represented By The Department Of Health And Human Services | Multideterminant peptide antigens |
FR2676071B1 (fr) * | 1991-05-02 | 1994-11-18 | Transgene Sa | Nouveau variant gp160 non-clivable, soluble, de forme hybride. |
AU665023B2 (en) * | 1991-08-29 | 1995-12-14 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Multideterminant peptide antigens that stimulate helper T lymphocyte response to HIV in a range of human subjects |
GB9208428D0 (en) * | 1992-04-16 | 1992-06-03 | Proteus Molecular Design | Synthetic polypeptides |
EP0572737B1 (de) * | 1992-06-04 | 2001-02-28 | The Research Foundation For Microbial Diseases Of Osaka University | Gag-Env Fusion-Antigen aus HIV |
DE4405810A1 (de) | 1994-02-23 | 1995-08-24 | Behringwerke Ag | Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung |
US6846905B2 (en) * | 1997-08-15 | 2005-01-25 | Abbott Laboratories | Antigen constructs useful in the detection and differentiation of antibodies to HIV |
AU2487300A (en) | 1998-12-31 | 2000-07-31 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
US7935805B1 (en) * | 1998-12-31 | 2011-05-03 | Novartis Vaccines & Diagnostics, Inc | Polynucleotides encoding antigenic HIV Type C polypeptides, polypeptides and uses thereof |
EP1141313A2 (de) * | 1998-12-31 | 2001-10-10 | Chiron Corporation | Verbesserte exprimierung von hiv polypeptiden und herstellung von virusähnliche partikeln |
WO2000039303A2 (en) | 1998-12-31 | 2000-07-06 | Chiron Corporation | Modified hiv env polypeptides |
CA2378539A1 (en) | 1999-07-06 | 2001-01-11 | Merck & Co., Inc. | Adenovirus carrying gag gene hiv vaccine |
US20030096778A1 (en) * | 2002-06-13 | 2003-05-22 | Shiver John W | Polynucleotide vaccines expressing codon optimized hiv-1 nef and modified hiv-1 nef |
US20040063653A1 (en) * | 2000-12-21 | 2004-04-01 | Shiver John W. | Polynucleotide vaccines expressing codon optimized hiv-1 pol and modified hiv-1 pol |
US6733993B2 (en) * | 2000-09-15 | 2004-05-11 | Merck & Co., Inc. | Enhanced first generation adenovirus vaccines expressing codon optimized HIV1-gag, pol, nef and modifications |
US20040101957A1 (en) * | 2001-09-14 | 2004-05-27 | Emini Emilio A. | Enhanced first generation adenovirus vaccines expressing codon optimized hiv1-gag, pol.nef and modifications |
DK1402015T3 (da) * | 2001-06-22 | 2011-12-05 | Hoffmann La Roche | Opløseligt kompleks omfattende et retroviralt overfladeglycoprotein og FkpA eller SlyD |
US7101683B2 (en) | 2001-06-26 | 2006-09-05 | Abbott Laboratories | Methods for the simultaneous detection of HCV antigens and HCV antibodies |
WO2003020876A2 (en) * | 2001-08-31 | 2003-03-13 | Chiron Corporation | Polynucleotides encoding antigenic hiv type b polypeptides, polypeptides and uses thereof |
US6852491B2 (en) * | 2001-09-04 | 2005-02-08 | Abbott Laboratories | Amplification and detection reagents for HIV-1 |
US7825233B2 (en) * | 2004-06-30 | 2010-11-02 | Allergan, Inc. | Optimizing expression of active Botulinum Toxin type E |
EP1773874B1 (de) * | 2004-08-04 | 2012-10-24 | Allergan, Inc. | Optimierung der expression von aktivem botulinumtoxin a |
WO2007141650A2 (en) * | 2006-01-17 | 2007-12-13 | Instituto De Medicina Molecular | Compositions and methods for diagnosing hiv-2 infection |
US8112229B2 (en) * | 2007-05-31 | 2012-02-07 | Abbott Laboratories | Method for determining the order of execution of assays of a sample in a laboratory automation system |
US8188250B2 (en) * | 2008-04-28 | 2012-05-29 | Butamax(Tm) Advanced Biofuels Llc | Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans |
EP2550362B1 (de) | 2010-03-25 | 2017-01-04 | Oregon Health&Science University | Cmv-glycoproteine und rekombinante vektoren |
WO2011163558A1 (en) | 2010-06-25 | 2011-12-29 | Abbott Laboratories | Materials and methods for assay of anti-hepatitis c virus (hcv) antibodies |
PT2691530T (pt) | 2011-06-10 | 2018-05-10 | Univ Oregon Health & Science | Glicoproteínas e vectores recombinantes cmv |
US20130189754A1 (en) | 2011-09-12 | 2013-07-25 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies |
US9402894B2 (en) | 2011-10-27 | 2016-08-02 | International Aids Vaccine Initiative | Viral particles derived from an enveloped virus |
US9689873B2 (en) | 2012-05-30 | 2017-06-27 | Bio-Rad Innovations | Method for diagnosing and differentiating HIV-2 infections |
ES2631608T3 (es) | 2012-06-27 | 2017-09-01 | International Aids Vaccine Initiative | Variante de la glicoproteína Env del VIH-1 |
US20150065381A1 (en) | 2013-09-05 | 2015-03-05 | International Aids Vaccine Initiative | Methods of identifying novel hiv-1 immunogens |
EP2873423B1 (de) | 2013-10-07 | 2017-05-31 | International Aids Vaccine Initiative | Lösliche hiv-1-hüllglykoproteintrimere |
EP3069730A3 (de) | 2015-03-20 | 2017-03-15 | International Aids Vaccine Initiative | Lösliche hiv-1-hüllglykoproteintrimere |
EP3072901A1 (de) | 2015-03-23 | 2016-09-28 | International Aids Vaccine Initiative | Lösliche hiv-1-hüllglykoproteintrimere |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2028287A (en) | 1931-01-02 | 1936-01-21 | William F Leicester | Process of making glued up plywood |
EP0001931A3 (de) * | 1977-11-08 | 1979-06-13 | Genentech, Inc. | Synthetisches DNS, Verfahren zur Herstellung und rekombinanter mikrobieller Cloning Vector welcher solches DNS enthält |
CA1341423C (en) * | 1984-10-31 | 2003-03-04 | Paul A. Luciw | Recombinant proteins of viruses associated with lymphadenopathy syndrome and/or acquired immune deficiency syndrome |
EP0187041B1 (de) * | 1984-12-24 | 1996-05-15 | Genentech, Inc. | Fusionen von AIDS-verwandten Polypeptiden |
DK171119B1 (da) * | 1985-04-19 | 1996-06-17 | Hoffmann La Roche | AIDS-viruskappeprotein, ekspressionsvektor bærende viruskappeproteinet, transformanter transformeret med ekspressionsvektoren, fremgangsmåde til fremstilling af viruskappeproteinet, fremgangsmåde til detektion af AIDS-antistoffer, fremgangsmåde til bestemmelse af AIDS-virus, vaccine mod AIDS, antistoffer mod viruskappeproteinet samt anvendelse af dette til fremstilling af en vaccine og til testnin |
JP2564268B2 (ja) * | 1985-08-28 | 1996-12-18 | 協和醗酵工業株式会社 | 融合抗原ポリペプチド |
US5079342A (en) | 1986-01-22 | 1992-01-07 | Institut Pasteur | Cloned DNA sequences related to the entire genomic RNA of human immunodeficiency virus II (HIV-2), polypeptides encoded by these DNA sequences and use of these DNA clones and polypeptides in diagnostic kits |
US4753873A (en) | 1986-02-03 | 1988-06-28 | Cambridge Bioscience Corporation | Peptides for the diagnosis of HTLV-III antibodies, their preparation and use |
US4925784A (en) | 1986-04-04 | 1990-05-15 | Hoffmann-La Roche Inc. | Expression and purification of an HTLV-III gag/env gene protein |
HUT50875A (en) * | 1986-11-01 | 1990-03-28 | Oxford Gene Systems Ltd | Process for producing particular hybrid hiv antigenes |
ES2104556T3 (es) * | 1987-01-16 | 1997-10-16 | Pasteur Institut | Peptidos que tienen propiedades inmunologicas de hiv-2. |
US4861707A (en) * | 1987-02-02 | 1989-08-29 | E. I. Du Pont De Nemours And Company | Human immunodeficiency virus antigen |
US5124255A (en) * | 1988-03-11 | 1992-06-23 | Abbott Laboratories | CKS method of protein synthesis |
JPH04502760A (ja) * | 1988-10-03 | 1992-05-21 | レプリゲン・コーポレーション | エイズの診断,予防および治療に有効な新規hiv蛋白質およびペプチド |
EP0400245B1 (de) * | 1989-05-31 | 1995-12-20 | Institut Pasteur | HIV-2-EHO-Retrovirus-Proteine und -Glycoproteine, Antikörper gegen sie, Verwendung für diagnostische Zwecke |
-
1989
- 1989-11-20 CA CA002003383A patent/CA2003383A1/en not_active Abandoned
- 1989-11-21 DE DE68927665T patent/DE68927665T2/de not_active Expired - Lifetime
- 1989-11-21 EP EP89121513A patent/EP0370458B1/de not_active Expired - Lifetime
- 1989-11-21 ES ES95114545T patent/ES2238071T3/es not_active Expired - Lifetime
- 1989-11-21 ES ES89121513T patent/ES2099066T3/es not_active Expired - Lifetime
- 1989-11-21 AT AT89121513T patent/ATE147758T1/de not_active IP Right Cessation
- 1989-11-21 AT AT95114545T patent/ATE286978T1/de not_active IP Right Cessation
- 1989-11-21 EP EP95114545A patent/EP0717109B1/de not_active Expired - Lifetime
- 1989-11-21 DE DE68929529T patent/DE68929529T2/de not_active Expired - Lifetime
- 1989-11-22 AU AU45458/89A patent/AU628108B2/en not_active Ceased
- 1989-11-24 JP JP01306353A patent/JP3073752B2/ja not_active Expired - Lifetime
-
1994
- 1994-09-29 US US08/314,570 patent/US5859193A/en not_active Expired - Fee Related
-
1995
- 1995-05-18 US US08/443,961 patent/US6153377A/en not_active Expired - Fee Related
- 1995-05-18 US US08/443,530 patent/US6538127B1/en not_active Expired - Fee Related
-
1997
- 1997-03-17 GR GR970400525T patent/GR3022850T3/el unknown
-
1999
- 1999-02-25 JP JP11048111A patent/JPH11313671A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP3073752B2 (ja) | 2000-08-07 |
AU628108B2 (en) | 1992-09-10 |
US5859193A (en) | 1999-01-12 |
ES2238071T3 (es) | 2005-08-16 |
DE68929529T2 (de) | 2005-12-29 |
CA2003383A1 (en) | 1990-05-23 |
AU4545889A (en) | 1990-07-05 |
DE68927665T2 (de) | 1997-07-17 |
DE68929529D1 (de) | 2005-02-17 |
EP0370458A2 (de) | 1990-05-30 |
GR3022850T3 (en) | 1997-06-30 |
ATE286978T1 (de) | 2005-01-15 |
JPH02273187A (ja) | 1990-11-07 |
US6538127B1 (en) | 2003-03-25 |
EP0717109A1 (de) | 1996-06-19 |
EP0370458B1 (de) | 1997-01-15 |
EP0370458A3 (de) | 1991-11-06 |
EP0717109B1 (de) | 2005-01-12 |
DE68927665D1 (de) | 1997-02-27 |
ES2099066T3 (es) | 1997-05-16 |
US6153377A (en) | 2000-11-28 |
JPH11313671A (ja) | 1999-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |