ATE241014T2 - Hiv-2 varianten - Google Patents

Hiv-2 varianten Download PDF

Info

Publication number
ATE241014T2
ATE241014T2 AT95100149T AT95100149T ATE241014T2 AT E241014 T2 ATE241014 T2 AT E241014T2 AT 95100149 T AT95100149 T AT 95100149T AT 95100149 T AT95100149 T AT 95100149T AT E241014 T2 ATE241014 T2 AT E241014T2
Authority
AT
Austria
Prior art keywords
hiv
variants
virus
rna
dna
Prior art date
Application number
AT95100149T
Other languages
English (en)
Inventor
Dr Karsten Henco
Briesen Hagen Von
Dr Andreas Immelmann
Dr Herbert Kuehnel
Dr Ursula Dietrich
Prof Dr Hel Ruebsamen-Waigmann
Michalina Adamski
Original Assignee
Qiagen Gmbh
Chemotherapeutisches Forschungsinstitut Georg Speyer Haus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6356522&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE241014(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Qiagen Gmbh, Chemotherapeutisches Forschungsinstitut Georg Speyer Haus filed Critical Qiagen Gmbh
Application granted granted Critical
Publication of ATE241014T2 publication Critical patent/ATE241014T2/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02Recovery or purification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16021Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/974Aids related test
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815Carrier is a synthetic polymer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/826Viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT95100149T 1988-06-14 1989-06-13 Hiv-2 varianten ATE241014T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3820223 1988-06-14

Publications (1)

Publication Number Publication Date
ATE241014T2 true ATE241014T2 (de) 2003-06-15

Family

ID=6356522

Family Applications (2)

Application Number Title Priority Date Filing Date
AT89710057T ATE141946T1 (de) 1988-06-14 1989-06-13 Hiv-2-virusvarianten
AT95100149T ATE241014T2 (de) 1988-06-14 1989-06-13 Hiv-2 varianten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT89710057T ATE141946T1 (de) 1988-06-14 1989-06-13 Hiv-2-virusvarianten

Country Status (9)

Country Link
US (2) US5637455A (de)
EP (2) EP0347365B1 (de)
JP (1) JP3088005B2 (de)
KR (1) KR960010948B1 (de)
AT (2) ATE141946T1 (de)
AU (1) AU625174B2 (de)
CA (1) CA1340747C (de)
DE (2) DE68929467T3 (de)
ES (1) ES2194029T5 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5278042A (en) * 1989-02-06 1994-01-11 The United States Of America As Represented By The Department Of Health & Human Services Method for detecting inhibitors of tat protein
DE3934366A1 (de) * 1989-10-14 1991-04-18 Chemotherapeutisches Forschungsinstitut Georg Speyer Haus Vakzine zum schutz vor hiv-virusinfektionen, verfahren zu ihrer herstellung und ihre verwendung als diagnostikum und immuntherapeutikum
US5605798A (en) 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US6428955B1 (en) 1995-03-17 2002-08-06 Sequenom, Inc. DNA diagnostics based on mass spectrometry
US5830655A (en) 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
US20030129589A1 (en) 1996-11-06 2003-07-10 Hubert Koster Dna diagnostics based on mass spectrometry
US5962665A (en) * 1997-06-16 1999-10-05 Abbott Laboratories Nucleic acid primers and probes for detecting HIV-1 and HIV-2
US6001558A (en) * 1997-06-25 1999-12-14 Ortho Clinical Diagnostics, Inc. Amplification and detection of HIV-1 and/or HIV 2
US6846905B2 (en) 1997-08-15 2005-01-25 Abbott Laboratories Antigen constructs useful in the detection and differentiation of antibodies to HIV
US6207370B1 (en) 1997-09-02 2001-03-27 Sequenom, Inc. Diagnostics based on mass spectrometric detection of translated target polypeptides
US6228128B1 (en) 1997-11-10 2001-05-08 Charlotte Johansen Antimicrobial activity of laccases
US6723564B2 (en) 1998-05-07 2004-04-20 Sequenom, Inc. IR MALDI mass spectrometry of nucleic acids using liquid matrices
US7244570B2 (en) 1998-08-04 2007-07-17 Luminex Molecular Diagnostics, Inc. Methods and compositions for modulating “marginally indiscriminant” hybridizations
US7332275B2 (en) 1999-10-13 2008-02-19 Sequenom, Inc. Methods for detecting methylated nucleotides
AU2002230545B2 (en) 2000-10-23 2006-09-21 Gen-Probe Incorporated Compositions and methods for detecting human immunodeficiency virus 2 (HIV-2)
US9394565B2 (en) 2003-09-05 2016-07-19 Agena Bioscience, Inc. Allele-specific sequence variation analysis
US7608394B2 (en) 2004-03-26 2009-10-27 Sequenom, Inc. Methods and compositions for phenotype identification based on nucleic acid methylation
EP1727911B1 (de) 2004-03-26 2013-01-23 Sequenom, Inc. Basenspezifische spaltung methylierungsspezifischer amplifikationsprodukte in kombination mit massenanalyse
JP2008537551A (ja) 2005-03-31 2008-09-18 カランド ファーマシューティカルズ, インコーポレイテッド リボヌクレオチドレダクターゼサブユニット2の阻害剤およびその使用
EP2620511B1 (de) 2008-01-17 2018-02-28 Sequenom, Inc. Einzelmolekül-Nukleinsäurensequenzanalyseverfahren
EP2550362B1 (de) 2010-03-25 2017-01-04 Oregon Health&Science University Cmv-glycoproteine und rekombinante vektoren
EP2710144B1 (de) 2011-05-19 2020-10-07 Agena Bioscience, Inc. Verfahren zur multiplex-identifizierung von nukleinsäuren
PL2691530T3 (pl) 2011-06-10 2019-02-28 Oregon Health & Science University Glikoproteiny i rekombinowane wektory CMV
EP2568289A3 (de) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunselektion von rekombinantem vesikulärem Stomatitisvirus mit Expression von HIV-1-Proteinen durch Breitbandneutralisierungs-Antikörper
EP2586461A1 (de) 2011-10-27 2013-05-01 Christopher L. Parks Von einem eingehüllten Virus abgeleitete Virenpartikel
EP2679596B1 (de) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 Env-proteinvariante
EP2848937A1 (de) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Verfahren zur Identifizierung neuartiger HIV-1-Immunogene
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
EP3069730A3 (de) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
CN107787371B (zh) 2015-04-24 2022-02-01 基纳生物技术有限公司 检测和定量次要变体的并行式方法
HK1250747A1 (zh) 2015-04-24 2019-01-11 Agena Bioscience, Inc. 用於次要等位基因和多态性的监定和定量的多重化方法
US9925258B2 (en) 2015-10-02 2018-03-27 International Aids Vaccine Initiative Replication-competent VSV-HIV Env vaccines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE195148T1 (de) 1986-01-22 2000-08-15 Pasteur Institut Prozess zur rekombinanten herstellung von hiv-2 - proteinen sowie zellen, die hiv-2 - proteine exprimiert
EP0269520A3 (de) * 1986-11-21 1988-08-24 Institut Pasteur Zum Hervorrufen von AIDS geeignetes Retrovirus vom HIV-2-Typ sowie seine Antigen- und Nukleinsäurebestandteile
US4956292A (en) * 1987-10-29 1990-09-11 Institut Pasteur Viral strain isolated from cerebrospinal fluid of an HIV seropositive man having acute and regressive encephalopathy and use of the strain in an immunoassay
AU3063389A (en) * 1988-01-08 1989-08-01 Dpz Deutsches Primatenzentrum Gesellschaft M.B.H. Hiv-2-type retroviruses of primates, vaccines, diagnostic and pharmaceutical compositions
WO1989009815A1 (en) * 1988-04-04 1989-10-19 Research Corporation Technologies, Inc. Novel virus of the hiv-2 family and methods of detection therefor

Also Published As

Publication number Publication date
EP0347365A3 (de) 1991-10-02
KR900000476A (ko) 1990-01-30
EP0655501B2 (de) 2016-07-27
JP3088005B2 (ja) 2000-09-18
US5637455A (en) 1997-06-10
DE68927025D1 (de) 1996-10-02
DE68929467D1 (de) 2003-06-26
DE68927025T2 (de) 1997-03-27
AU625174B2 (en) 1992-07-02
CA1340747C (en) 1999-09-14
ATE141946T1 (de) 1996-09-15
ES2194029T5 (es) 2016-10-26
EP0347365A2 (de) 1989-12-20
EP0655501A1 (de) 1995-05-31
EP0655501B1 (de) 2003-05-21
US5677147A (en) 1997-10-14
EP0347365B1 (de) 1996-08-28
ES2194029T3 (es) 2003-11-16
DE68929467T2 (de) 2004-04-15
AU3636189A (en) 1990-03-29
DE68929467T3 (de) 2016-12-22
KR960010948B1 (ko) 1996-08-14
JPH02131576A (ja) 1990-05-21

Similar Documents

Publication Publication Date Title
DE68929467D1 (de) HIV-2 Varianten
GR3034708T3 (en) Retrovirus of the type HIV-2 capable of inducing AIDS, and the antigenic and nucleic acid components thereof.
DE10399032I1 (de) Rekombinante Viren.
FI864016A0 (fi) Med rekombinant-dna-teknik erhaollen kolonistimulerande faktor-1.
CA2011878A1 (en) Immunogenic regions on the e7 protein of human papillomavirus type 16
NO871025D0 (no) Polypeptid, dna og fremgangsmaate for fremstilling derav.
NO912825L (no) Fremgangsmaate for fremstilling av kokonjugatvaksiner omfattende im munogent protein, hiv-beslektede peptider og anioniske grupper.
DK0817851T5 (da) DNA, der koder for humant papillomvirus type 18
DK476688D0 (da) Hiv-proteiner og -peptider, der er nyttige ved aids-diagnose, -profylakse og -terapi
DE69016935D1 (de) Laserkamera zur Abtastung des Augenhintergrundes.
FI971275A7 (fi) Inaktivoidun IVa2-geenin käsittävät epätäydelliset yhdistelmä-DNA-tekn iset adenovirukset
ATE103980T1 (de) Das f-protein vom aids-virus enthaltender impfstoff.
DK498387A (da) Virus-dna-sekvens
ATE124991T1 (de) Humaner papillomvirus typ 57, seine dna und die davon kodierten proteine.
DK161487D0 (da) Alfa-interferon-analoge og fremgangsmaade til fremstilling deraf samt udtrykkelsesvektorer og vaertsorganismer til anvendelse ved fremgangsmaaden.
DK0490383T3 (da) Peptider af HIV-gag-proteinet, fremstilling og anvendelse deraf
EP0311228A3 (de) Rekombinante Polypeptide und ihre Verwendung einschliesslich Nachweisverfahren für AIDS-Virus
ATE107695T1 (de) Virusvektor und rekombinante dns, die ein oder mehrere strukturelle proteine (ha,f und/oder np) eines morbillivirus kodieren.
NO891691D0 (no) Rekombinant gag-forloeper for hiv.
FI893346A0 (fi) Icke-reverterande rna-virus.
FI871046L (fi) Saett att tillsaetta luktaemne till oxygengas.
IT8919930A0 (it) Procedimento per marcare cromosomi utilizzando dna ripetitivo ricombinante.
ATE102252T1 (de) Rekombinantes gefluegelpockenvirus, expressionsvektoren fuer heterologische proteine und davon derivierte gefluegelvakzine.
AUPN003194A0 (en) Vaccine for the hiv-1 & hiv-2 virus
IE870898L (en) Recombinant vaccinia virus.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0655501

Country of ref document: EP

EELA Cancelled due to lapse of time