ATE145331T1 - Verwendung von in situ modifikation von alginat zur vorbeugung von gewebeadhäsion - Google Patents

Verwendung von in situ modifikation von alginat zur vorbeugung von gewebeadhäsion

Info

Publication number
ATE145331T1
ATE145331T1 AT93908588T AT93908588T ATE145331T1 AT E145331 T1 ATE145331 T1 AT E145331T1 AT 93908588 T AT93908588 T AT 93908588T AT 93908588 T AT93908588 T AT 93908588T AT E145331 T1 ATE145331 T1 AT E145331T1
Authority
AT
Austria
Prior art keywords
situ
alginate
articular
situ modification
tissue adhesion
Prior art date
Application number
AT93908588T
Other languages
English (en)
Inventor
Harold M Aberman
James J Barry
Paul A Higham
Original Assignee
Howmedica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Howmedica filed Critical Howmedica
Application granted granted Critical
Publication of ATE145331T1 publication Critical patent/ATE145331T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/042—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Vascular Medicine (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Polymers & Plastics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT93908588T 1992-06-30 1993-04-02 Verwendung von in situ modifikation von alginat zur vorbeugung von gewebeadhäsion ATE145331T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/906,953 US5266326A (en) 1992-06-30 1992-06-30 In situ modification of alginate

Publications (1)

Publication Number Publication Date
ATE145331T1 true ATE145331T1 (de) 1996-12-15

Family

ID=25423289

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93908588T ATE145331T1 (de) 1992-06-30 1993-04-02 Verwendung von in situ modifikation von alginat zur vorbeugung von gewebeadhäsion

Country Status (11)

Country Link
US (1) US5266326A (de)
EP (1) EP0648122B1 (de)
JP (1) JPH07504682A (de)
AT (1) ATE145331T1 (de)
AU (1) AU671114B2 (de)
CA (1) CA2139311A1 (de)
DE (1) DE69306114T2 (de)
DK (1) DK0648122T3 (de)
ES (1) ES2094537T3 (de)
GR (1) GR3022093T3 (de)
WO (1) WO1994000134A1 (de)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
DE69426530D1 (de) * 1993-10-04 2001-02-08 Maurizio Tonetti Pharmazeutische zusammensetzung zur förderung der gewebeheilung und -regenerierung und darreichungssatz
US5931165A (en) * 1994-09-06 1999-08-03 Fusion Medical Technologies, Inc. Films having improved characteristics and methods for their preparation and use
US6150581A (en) * 1995-06-07 2000-11-21 United States Surgical Corporation Chitosan/alginate anti-adhesion barrier
US5791352A (en) * 1996-06-19 1998-08-11 Fusion Medical Technologies, Inc. Methods and compositions for inhibiting tissue adhesion
US5906997A (en) * 1997-06-17 1999-05-25 Fzio Med, Inc. Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions
US20050074495A1 (en) * 1997-06-17 2005-04-07 Fziomed, Inc. Compositions of polyacids and methods for their use in reducing adhesions
US20040096422A1 (en) * 1997-06-17 2004-05-20 Schwartz Herbert E. Compositions of polyacids and polyethers and methods for their use in reducing pain
US7192984B2 (en) * 1997-06-17 2007-03-20 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use as dermal fillers
US6869938B1 (en) 1997-06-17 2005-03-22 Fziomed, Inc. Compositions of polyacids and polyethers and methods for their use in reducing adhesions
CA2212300A1 (en) 1997-08-04 1999-02-04 Abdellatif Chenite In vitro or in vivo gelfying chitosan and therapeutic uses thereof
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6818018B1 (en) 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
US6514534B1 (en) 1998-08-14 2003-02-04 Incept Llc Methods for forming regional tissue adherent barriers and drug delivery systems
US6302848B1 (en) 1999-07-01 2001-10-16 Sonotech, Inc. In vivo biocompatible acoustic coupling media
KR20010010151A (ko) * 1999-07-16 2001-02-05 김윤 수용성 알긴산염과 카르복시메틸 셀룰로오스를 주성분으로 하는 유착방지제 및 그의 제조방법
EP1229940B1 (de) 1999-11-15 2014-05-14 Piramal Healthcare (Canada) Limited Temperaturgesteuerte und ph-abhängige selbstgelierende biopolymere wässrige lösung
CA2396431A1 (en) * 1999-11-29 2001-05-31 Advanced Research And Technology Institute, Inc. Sustained percutaneous delivery of a biologically active substance
US20030158302A1 (en) * 1999-12-09 2003-08-21 Cyric Chaput Mineral-polymer hybrid composition
EP1255576B1 (de) * 1999-12-09 2003-08-20 Biosyntech Canada Inc. Mineral-polymer hybrid-zusammensetzung
US6566345B2 (en) 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
US6638917B1 (en) 2000-02-25 2003-10-28 Scimed Life Systems, Inc. Reducing adhesion
GB0005743D0 (en) * 2000-03-10 2000-05-03 Reckitt & Colmann Prod Ltd Pharmaceutical compositions including alginates
CA2407235A1 (en) * 2000-04-28 2001-11-08 Fziomed, Inc. Hemostatic compositions of polyacids and polyalkylene oxides and methods for their use
KR20010107067A (ko) * 2000-05-25 2001-12-07 김정식 유착방지제
KR100880622B1 (ko) 2000-06-29 2009-01-30 바이오신텍 캐나다 인코포레이티드 연골 및 다른 조직의 복구 및 재생용 조성물 및 방법
US6989373B2 (en) * 2000-11-15 2006-01-24 Bio Syntech Canada Inc. Method for restoring a fat-pad
WO2002040070A2 (en) * 2000-11-15 2002-05-23 Bio Syntech Canada Inc. Method for restoring a damaged or degenerated intervertebral disc
JP5614913B2 (ja) * 2002-07-16 2014-10-29 ピラマル ヘルスケア （カナダ） リミテッド 生細胞又は生物学的活性因子を封入し送達するための、細胞適合性、注射可能、かつ自己ゲル化性のキトサン溶液の組成物
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
JP2006519659A (ja) * 2003-03-10 2006-08-31 ザ・リージェンツ・オブ・ジ・ユニバーシティ・オブ・ミシガン アルギネート硬膜シーラントの組成物および使用方法
KR20060034227A (ko) * 2003-05-30 2006-04-21 에이알씨 파마시유티칼즈 인코포레이티드 다양한 제제를 사용하여 섬유성 유착을 억제하는 것에 관한약제학적 조성물 및 방법
US20050118206A1 (en) * 2003-11-14 2005-06-02 Luk Andrew S. Surfactant-based gel as an injectable, sustained drug delivery vehicle
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US8062272B2 (en) 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
CA2583373C (en) * 2004-10-12 2013-09-03 Fmc Biopolymer As Self-gelling alginate systems and uses thereof
US8663225B2 (en) 2004-11-12 2014-03-04 Medtronic, Inc. Hydrogel bone void filler
EP1945712A4 (de) * 2005-11-04 2013-05-01 Piramal Healthcare Canada Ltd Gelbindung von wässrigen polyelektrolytlösungen durch thermisch induzierte änderungen des ionisationszustands
DE102006029500A1 (de) * 2006-06-27 2008-01-03 Schulz, Hans H. Verwendung einer antimikrobiellen härtenden Alginatmasse zur topischen Behandlung von Wunden und Entzündungen in der Human-, Zahn- und Veterinärmedizin
WO2008097581A1 (en) * 2007-02-06 2008-08-14 Incept, Llc Polymerization with precipitation of proteins for elution in physiological solution
AU2008217916B2 (en) * 2007-02-21 2013-03-21 Mochida Pharmaceutical Co., Ltd. Composition for treatment of cartilage disease
CN103463638A (zh) * 2007-08-28 2013-12-25 Fmc有限公司 延迟的自胶凝藻酸盐体系及其应用
WO2009063291A1 (en) * 2007-11-13 2009-05-22 Bio-Technology General (Israel) Ltd. Dilute filtration sterilization process for viscoelastic biopolymers
US20090149746A1 (en) * 2007-11-19 2009-06-11 Rubicor Medical, Inc. Post-biopsy cavity treatment implants and methods
GB0722820D0 (en) 2007-11-21 2008-01-02 Smith & Nephew Vacuum assisted wound dressing
WO2009067711A2 (en) 2007-11-21 2009-05-28 T.J. Smith & Nephew, Limited Suction device and dressing
HUE049431T2 (hu) 2007-11-21 2020-09-28 Smith & Nephew Sebkötözés
US20130096518A1 (en) 2007-12-06 2013-04-18 Smith & Nephew Plc Wound filling apparatuses and methods
GB0723875D0 (en) 2007-12-06 2008-01-16 Smith & Nephew Wound management
US11253399B2 (en) 2007-12-06 2022-02-22 Smith & Nephew Plc Wound filling apparatuses and methods
ITRM20080037A1 (it) * 2008-01-23 2009-07-24 Uni Degli Studi Perugia Procedimento per la ultrapurificazione di alginati.
US8668863B2 (en) 2008-02-26 2014-03-11 Board Of Regents, The University Of Texas System Dendritic macroporous hydrogels prepared by crystal templating
GB0803564D0 (en) 2008-02-27 2008-04-02 Smith & Nephew Fluid collection
EP2095832A1 (de) 2008-02-28 2009-09-02 Bayer MaterialScience AG Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile.
DE102008022086A1 (de) * 2008-05-05 2009-11-12 Schulz, Hans H. Zweikomponenten-Alginat
US8367637B2 (en) * 2008-08-19 2013-02-05 Mochida Pharmaceutical Co., Ltd. Composition for treating arthritic disorder
CA2750242C (en) 2009-02-12 2018-05-22 Incept, Llc Drug delivery through hydrogel plugs
US8252317B2 (en) * 2009-02-26 2012-08-28 General Electric Company Metal alginate hydrogel and articles thereof
WO2010117266A1 (en) 2009-04-06 2010-10-14 Broockeville Corporation N.V. In situ gelling alginate systems
US9061095B2 (en) 2010-04-27 2015-06-23 Smith & Nephew Plc Wound dressing and method of use
GB201011173D0 (en) 2010-07-02 2010-08-18 Smith & Nephew Provision of wound filler
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
US9095558B2 (en) 2010-10-08 2015-08-04 Board Of Regents, The University Of Texas System Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications
BR112013012785A2 (pt) 2010-11-25 2020-10-20 Bluestar Silicones France Sas composição i - ii e produtos e usos das mesmas
GB201020005D0 (en) 2010-11-25 2011-01-12 Smith & Nephew Composition 1-1
RU2463986C2 (ru) * 2010-12-13 2012-10-20 Федеральное государственное бюджетное учреждение "Российский научный центр "Восстановительная травматология и ортопедия" имени академика Г.А. Илизарова" Министерства здравоохранения и социального развития Российской Федерации (ФГБУ "РНЦ "ВТО" им. акад. Г.А. Илизарова" Минздравсоцразвития России) Способ стимуляции репаративных процессов при лечении внутрисуставных переломов
EP2783704A4 (de) * 2011-11-25 2015-04-15 Otsuka Pharma Co Ltd Pharmazeutische zusammensetzung zur haftungs- oder hämostaseverhinderung
US20150159066A1 (en) 2011-11-25 2015-06-11 Smith & Nephew Plc Composition, apparatus, kit and method and uses thereof
EP2612846A1 (de) 2012-01-09 2013-07-10 Bayer MaterialScience AG Beta-Aminosäureester und deren Verwendung
US11565027B2 (en) 2012-12-11 2023-01-31 Board Of Regents, The University Of Texas System Hydrogel membrane for adhesion prevention
WO2014102802A1 (en) * 2012-12-30 2014-07-03 Hadasit Medical Research Services And Development Ltd. Alginate compositions and uses thereof
US20160120706A1 (en) 2013-03-15 2016-05-05 Smith & Nephew Plc Wound dressing sealant and use thereof
BR112016026064B1 (pt) * 2014-05-05 2021-08-17 Sealantis Ltd Adesivos e vedantes biológicos e métodos de uso dos mesmos
SG11201609593RA (en) * 2014-05-16 2016-12-29 Ultrast Inc Phase-shifting formulations
WO2018165327A1 (en) 2017-03-08 2018-09-13 Alafair Biosciences, Inc. Hydrogel medium for the storage and preservation of tissue
CN113521398A (zh) * 2021-08-10 2021-10-22 青岛琛蓝海洋生物工程有限公司 一种原位可注射防粘连凝胶及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57167919A (en) * 1981-04-07 1982-10-16 Hirozo Ohira Preventing agent for intraperitoneal adhesion
CA1202904A (en) * 1983-11-21 1986-04-08 Brian G. Sparkes Chitosan based wound dressing materials
DE3601132A1 (de) * 1986-01-16 1987-07-23 Christian Bannert Verfahren zur behandlung der schleimhaut
US4948575A (en) * 1989-01-24 1990-08-14 Minnesota Mining And Manufacturing Company Alginate hydrogel foam wound dressing
GB8911177D0 (en) * 1989-05-16 1989-07-05 Vilain Jean Alginate gel pharmaceutical product
US5093319A (en) * 1989-10-31 1992-03-03 Pfizer Hospital Products Group, Inc. Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions
US4994277A (en) * 1989-10-31 1991-02-19 Pfizer Hospital Products Group, Inc. Use of xanthan gum for preventing adhesions

Also Published As

Publication number Publication date
GR3022093T3 (en) 1997-03-31
WO1994000134A1 (en) 1994-01-06
US5266326A (en) 1993-11-30
EP0648122B1 (de) 1996-11-20
DK0648122T3 (da) 1996-12-09
EP0648122A1 (de) 1995-04-19
JPH07504682A (ja) 1995-05-25
DE69306114D1 (de) 1997-01-02
CA2139311A1 (en) 1994-01-06
ES2094537T3 (es) 1997-01-16
AU3935693A (en) 1994-01-24
DE69306114T2 (de) 1997-03-13
AU671114B2 (en) 1996-08-15

Similar Documents

Publication Publication Date Title
ATE145331T1 (de) Verwendung von in situ modifikation von alginat zur vorbeugung von gewebeadhäsion
US5866415A (en) Materials for healing cartilage and bone defects
CA2110527A1 (fr) Procede de traitement des tissus osseux et biomateriaux implantables correspondants
ATE201602T1 (de) Verbessertes verfahren zur fixierung von verkalkungsbestendigen biologischen geweben
ES8600613A1 (es) Procedimiento para el tratamiento de tejidos corporales
ES8801111A1 (es) Un procedimiento para la preparacion de un biomaterial a base de un n-acil-citosano y colageno.
FI942895A0 (fi) Kudosten ohjattuun regenerointiin tarkoitetut yhdistelmämateriaalikalvot
ATE273722T1 (de) Injektierbare oder implantierbare biomaterialien zum füllen oder abdecken von hohlräumen und lumen eines körpers
GR3002084T3 (en) Biomaterials based on mixtures of collagen, chitosan and glycosaminoglycans, method for preparing them and their use in human medicine
BR9306375A (pt) Reposiçao de pele viva e processos para a produçao da mesma e de uso de microesferas revestidas de células
BR9407992A (pt) Método para melhorar as reaçoes biológicas a um dispositivo que é cirurgicamente implantável em osso vivo dispositivo protético cirurgicamente implantável em osso vivo implante dental substancialmente cilíndrico método para aumentar a retençao mecânica de um dispositivo que é cirurgicamente implantável em osso vivo
IL115721A (en) Device for the modulation of cell proliferation and wound healing and methods for its preparation
CA2070586A1 (en) Prosthetic Implant
DE60020330D1 (de) Eiweissschaum klebstoff zur chirurgischen und/oder therapeutischen verwendung
NO924697D0 (no) Kirurgisk implantat og en fremgangsmaate for behandling avkirurgisk implantat
ATE242960T1 (de) Vorrichtung und verfahren zur photoaktivierung
DE69943067D1 (de) Verwendung von dreidimensionalen Prothesen, die Hyaluronsäurederivate enthalten
ES2014843A6 (es) Matriz de crecimiento oseo y procedimiento para su fabricacion.
DE69903945D1 (de) Dreidimensionale biomaterialien, frei von zellulären komponenten und produkten, enthaltend hyaluronsäure-derivate, für die in-vivo regeneration von gewebezellen
EP0276836A3 (de) Implantierbares Material und Verfahren zu seiner Herstellung
EP0968729A3 (de) Knochenregenerierungsmaterial
DE69920015D1 (de) Verfahren zur induktion der herstellung von wachstumsfaktoren
ATE382378T1 (de) Implantatmaterial
ATE190507T1 (de) Biodegradierbare führungskanäle zur verwendung als chirurgische hilfsmittel in gewebewiederherstellung
Saha Tissue engineered successful reconstruction of a complex traumatized lower extremity

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee