ATE145331T1 - Verwendung von in situ modifikation von alginat zur vorbeugung von gewebeadhäsion - Google Patents
Verwendung von in situ modifikation von alginat zur vorbeugung von gewebeadhäsionInfo
- Publication number
- ATE145331T1 ATE145331T1 AT93908588T AT93908588T ATE145331T1 AT E145331 T1 ATE145331 T1 AT E145331T1 AT 93908588 T AT93908588 T AT 93908588T AT 93908588 T AT93908588 T AT 93908588T AT E145331 T1 ATE145331 T1 AT E145331T1
- Authority
- AT
- Austria
- Prior art keywords
- situ
- alginate
- articular
- situ modification
- tissue adhesion
- Prior art date
Links
- 235000010443 alginic acid Nutrition 0.000 title abstract 3
- 229920000615 alginic acid Polymers 0.000 title abstract 3
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 title abstract 2
- 229940072056 alginate Drugs 0.000 title abstract 2
- 238000012986 modification Methods 0.000 title abstract 2
- 230000004048 modification Effects 0.000 title abstract 2
- 208000031737 Tissue Adhesions Diseases 0.000 title 1
- 238000011065 in-situ storage Methods 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 2
- 229960001126 alginic acid Drugs 0.000 abstract 1
- 239000000783 alginic acid Substances 0.000 abstract 1
- 150000004781 alginic acids Chemical class 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/906,953 US5266326A (en) | 1992-06-30 | 1992-06-30 | In situ modification of alginate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE145331T1 true ATE145331T1 (de) | 1996-12-15 |
Family
ID=25423289
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93908588T ATE145331T1 (de) | 1992-06-30 | 1993-04-02 | Verwendung von in situ modifikation von alginat zur vorbeugung von gewebeadhäsion |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5266326A (de) |
| EP (1) | EP0648122B1 (de) |
| JP (1) | JPH07504682A (de) |
| AT (1) | ATE145331T1 (de) |
| AU (1) | AU671114B2 (de) |
| CA (1) | CA2139311A1 (de) |
| DE (1) | DE69306114T2 (de) |
| DK (1) | DK0648122T3 (de) |
| ES (1) | ES2094537T3 (de) |
| GR (1) | GR3022093T3 (de) |
| WO (1) | WO1994000134A1 (de) |
Families Citing this family (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5709854A (en) * | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| CN1056973C (zh) * | 1993-10-04 | 2000-10-04 | 毛里齐奥·托内蒂 | 促进组织愈合和再生的药物组合物及包含其的施用药盒 |
| US5931165A (en) * | 1994-09-06 | 1999-08-03 | Fusion Medical Technologies, Inc. | Films having improved characteristics and methods for their preparation and use |
| US6150581A (en) * | 1995-06-07 | 2000-11-21 | United States Surgical Corporation | Chitosan/alginate anti-adhesion barrier |
| US5791352A (en) * | 1996-06-19 | 1998-08-11 | Fusion Medical Technologies, Inc. | Methods and compositions for inhibiting tissue adhesion |
| US7192984B2 (en) * | 1997-06-17 | 2007-03-20 | Fziomed, Inc. | Compositions of polyacids and polyethers and methods for their use as dermal fillers |
| US6869938B1 (en) | 1997-06-17 | 2005-03-22 | Fziomed, Inc. | Compositions of polyacids and polyethers and methods for their use in reducing adhesions |
| US20040096422A1 (en) * | 1997-06-17 | 2004-05-20 | Schwartz Herbert E. | Compositions of polyacids and polyethers and methods for their use in reducing pain |
| US5906997A (en) * | 1997-06-17 | 1999-05-25 | Fzio Med, Inc. | Bioresorbable compositions of carboxypolysaccharide polyether intermacromolecular complexes and methods for their use in reducing surgical adhesions |
| US20050074495A1 (en) * | 1997-06-17 | 2005-04-07 | Fziomed, Inc. | Compositions of polyacids and methods for their use in reducing adhesions |
| CA2212300A1 (en) | 1997-08-04 | 1999-02-04 | Abdellatif Chenite | In vitro or in vivo gelfying chitosan and therapeutic uses thereof |
| US6514534B1 (en) * | 1998-08-14 | 2003-02-04 | Incept Llc | Methods for forming regional tissue adherent barriers and drug delivery systems |
| US6632457B1 (en) | 1998-08-14 | 2003-10-14 | Incept Llc | Composite hydrogel drug delivery systems |
| US6818018B1 (en) | 1998-08-14 | 2004-11-16 | Incept Llc | In situ polymerizable hydrogels |
| US6302848B1 (en) | 1999-07-01 | 2001-10-16 | Sonotech, Inc. | In vivo biocompatible acoustic coupling media |
| KR20010010151A (ko) * | 1999-07-16 | 2001-02-05 | 김윤 | 수용성 알긴산염과 카르복시메틸 셀룰로오스를 주성분으로 하는 유착방지제 및 그의 제조방법 |
| WO2001036000A1 (en) | 1999-11-15 | 2001-05-25 | Bio Syntech Canada, Inc. | Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution |
| EP1233751A1 (de) * | 1999-11-29 | 2002-08-28 | ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, Inc. | Verzögerte percutane verabreichung einer biologisch aktiven substanz |
| US20030158302A1 (en) * | 1999-12-09 | 2003-08-21 | Cyric Chaput | Mineral-polymer hybrid composition |
| DE60004710T2 (de) * | 1999-12-09 | 2004-07-08 | Biosyntech Canada Inc., Laval | Mineral-polymer hybrid-zusammensetzung |
| US6566345B2 (en) | 2000-04-28 | 2003-05-20 | Fziomed, Inc. | Polyacid/polyalkylene oxide foams and gels and methods for their delivery |
| US6638917B1 (en) | 2000-02-25 | 2003-10-28 | Scimed Life Systems, Inc. | Reducing adhesion |
| GB0005743D0 (en) * | 2000-03-10 | 2000-05-03 | Reckitt & Colmann Prod Ltd | Pharmaceutical compositions including alginates |
| DE60138020D1 (de) * | 2000-04-28 | 2009-04-30 | Fziomed Inc | Haemostatische zusammenstellung von polysäuren und polyalkylenoxyden und deren verwendungsmethoden |
| KR20010107067A (ko) * | 2000-05-25 | 2001-12-07 | 김정식 | 유착방지제 |
| ATE320277T1 (de) | 2000-06-29 | 2006-04-15 | Biosyntech Canada Inc | Zusammensetzung und verfahren zur reparatur und regenerierung von knorpel und anderen geweben |
| US6989373B2 (en) * | 2000-11-15 | 2006-01-24 | Bio Syntech Canada Inc. | Method for restoring a fat-pad |
| AU2002221370A1 (en) * | 2000-11-15 | 2002-05-27 | Bio Syntech Canada Inc | Method for restoring a damaged or degenerated intervertebral disc |
| ATE481110T1 (de) * | 2002-07-16 | 2010-10-15 | Biosyntech Canada Inc | Zusammensetzung für die herstellung zellkompatibler, injizierbarer, selbstgelierender chitosan lösungen zum einkapseln und verabreichen von lebenden zellen oderbiologisch aktiven faktoren |
| US7846141B2 (en) | 2002-09-03 | 2010-12-07 | Bluesky Medical Group Incorporated | Reduced pressure treatment system |
| GB0224986D0 (en) | 2002-10-28 | 2002-12-04 | Smith & Nephew | Apparatus |
| WO2004080343A2 (en) * | 2003-03-10 | 2004-09-23 | The Regents Of The University Of Michigan | Compositions and methods for use of alginate dural sealants |
| JP2007504273A (ja) * | 2003-05-30 | 2007-03-01 | エーアールシー ファーマシューティカルズ,インク. | 種々の作用剤を用いた、線維性癒着の抑制に関する医薬組成物及び方法 |
| US20050118206A1 (en) * | 2003-11-14 | 2005-06-02 | Luk Andrew S. | Surfactant-based gel as an injectable, sustained drug delivery vehicle |
| US7909805B2 (en) | 2004-04-05 | 2011-03-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
| US8062272B2 (en) | 2004-05-21 | 2011-11-22 | Bluesky Medical Group Incorporated | Flexible reduced pressure treatment appliance |
| US10058642B2 (en) | 2004-04-05 | 2018-08-28 | Bluesky Medical Group Incorporated | Reduced pressure treatment system |
| GB0409446D0 (en) | 2004-04-28 | 2004-06-02 | Smith & Nephew | Apparatus |
| MX2007004261A (es) * | 2004-10-12 | 2007-06-18 | Fmc Biopolymer As | Sistemas de alginato auto-gelificantes y usos de los mismos. |
| US8663225B2 (en) | 2004-11-12 | 2014-03-04 | Medtronic, Inc. | Hydrogel bone void filler |
| WO2007051311A1 (en) * | 2005-11-04 | 2007-05-10 | Bio Syntech Canada Inc. | Gel formation of polyelectrolyte aqueous solutions by thermally induced changes in ionization state |
| DE102006029500A1 (de) * | 2006-06-27 | 2008-01-03 | Schulz, Hans H. | Verwendung einer antimikrobiellen härtenden Alginatmasse zur topischen Behandlung von Wunden und Entzündungen in der Human-, Zahn- und Veterinärmedizin |
| CA2677532A1 (en) * | 2007-02-06 | 2008-08-14 | Incept, Llc | Polymerization with precipitation of proteins for elution in physiological solution |
| AU2008217916B2 (en) | 2007-02-21 | 2013-03-21 | Mochida Pharmaceutical Co., Ltd. | Composition for treatment of cartilage disease |
| JP2010537717A (ja) * | 2007-08-28 | 2010-12-09 | エフ エム シー コーポレーション | 遅効性自己ゲル化アルギネートシステムおよびその用途 |
| RU2501811C2 (ru) * | 2007-11-13 | 2013-12-20 | Био-Текнолоджи Дженерал (Изрейел) Лтд. | Способ стерилизации посредством фильтрации разбавленных вязкоэластичных биополимеров (варианты) |
| US20090149746A1 (en) * | 2007-11-19 | 2009-06-11 | Rubicor Medical, Inc. | Post-biopsy cavity treatment implants and methods |
| EP3000448B2 (de) | 2007-11-21 | 2022-03-09 | Smith & Nephew PLC | Wundauflage |
| GB0722820D0 (en) | 2007-11-21 | 2008-01-02 | Smith & Nephew | Vacuum assisted wound dressing |
| WO2009067711A2 (en) | 2007-11-21 | 2009-05-28 | T.J. Smith & Nephew, Limited | Suction device and dressing |
| US20130096518A1 (en) | 2007-12-06 | 2013-04-18 | Smith & Nephew Plc | Wound filling apparatuses and methods |
| US11253399B2 (en) | 2007-12-06 | 2022-02-22 | Smith & Nephew Plc | Wound filling apparatuses and methods |
| GB0723875D0 (en) | 2007-12-06 | 2008-01-16 | Smith & Nephew | Wound management |
| ITRM20080037A1 (it) * | 2008-01-23 | 2009-07-24 | Uni Degli Studi Perugia | Procedimento per la ultrapurificazione di alginati. |
| WO2009108760A2 (en) | 2008-02-26 | 2009-09-03 | Board Of Regents, The University Of Texas System | Dendritic macroporous hydrogels prepared by crystal templating |
| GB0803564D0 (en) | 2008-02-27 | 2008-04-02 | Smith & Nephew | Fluid collection |
| EP2095832A1 (de) | 2008-02-28 | 2009-09-02 | Bayer MaterialScience AG | Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile. |
| DE102008022086A1 (de) * | 2008-05-05 | 2009-11-12 | Schulz, Hans H. | Zweikomponenten-Alginat |
| US8367637B2 (en) * | 2008-08-19 | 2013-02-05 | Mochida Pharmaceutical Co., Ltd. | Composition for treating arthritic disorder |
| CA2750242C (en) * | 2009-02-12 | 2018-05-22 | Incept, Llc | Drug delivery through hydrogel plugs |
| GB0902816D0 (en) | 2009-02-19 | 2009-04-08 | Smith & Nephew | Fluid communication path |
| US8252317B2 (en) * | 2009-02-26 | 2012-08-28 | General Electric Company | Metal alginate hydrogel and articles thereof |
| WO2010117266A1 (en) | 2009-04-06 | 2010-10-14 | Broockeville Corporation N.V. | In situ gelling alginate systems |
| US9061095B2 (en) | 2010-04-27 | 2015-06-23 | Smith & Nephew Plc | Wound dressing and method of use |
| GB201011173D0 (en) | 2010-07-02 | 2010-08-18 | Smith & Nephew | Provision of wound filler |
| WO2012048283A1 (en) | 2010-10-08 | 2012-04-12 | Board Of Regents, The University Of Texas System | One-step processing of hydrogels for mechanically robust and chemically desired features |
| JP6042815B2 (ja) | 2010-10-08 | 2016-12-14 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム | 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜 |
| WO2012069794A1 (en) | 2010-11-25 | 2012-05-31 | Smith & Nephew Plc | Composition i-ii and products and uses thereof |
| GB201020005D0 (en) | 2010-11-25 | 2011-01-12 | Smith & Nephew | Composition 1-1 |
| RU2463986C2 (ru) * | 2010-12-13 | 2012-10-20 | Федеральное государственное бюджетное учреждение "Российский научный центр "Восстановительная травматология и ортопедия" имени академика Г.А. Илизарова" Министерства здравоохранения и социального развития Российской Федерации (ФГБУ "РНЦ "ВТО" им. акад. Г.А. Илизарова" Минздравсоцразвития России) | Способ стимуляции репаративных процессов при лечении внутрисуставных переломов |
| US20150159066A1 (en) | 2011-11-25 | 2015-06-11 | Smith & Nephew Plc | Composition, apparatus, kit and method and uses thereof |
| EP2783704A4 (de) * | 2011-11-25 | 2015-04-15 | Otsuka Pharma Co Ltd | Pharmazeutische zusammensetzung zur haftungs- oder hämostaseverhinderung |
| EP2612846A1 (de) | 2012-01-09 | 2013-07-10 | Bayer MaterialScience AG | Beta-Aminosäureester und deren Verwendung |
| EP4253454A3 (de) | 2012-12-11 | 2024-01-03 | Board of Regents, The University of Texas System | Hydrogelmembran zur anhaftungsverhinderung |
| US11565027B2 (en) | 2012-12-11 | 2023-01-31 | Board Of Regents, The University Of Texas System | Hydrogel membrane for adhesion prevention |
| EP2938348A4 (de) * | 2012-12-30 | 2016-07-27 | Hadasit Med Res Service | Alginatezusammensetzungen und verwendungen davon |
| US20160120706A1 (en) | 2013-03-15 | 2016-05-05 | Smith & Nephew Plc | Wound dressing sealant and use thereof |
| EP2968647B1 (de) | 2013-03-15 | 2022-06-29 | Smith & Nephew plc | Wundverbanddichtmasse und verwendung davon |
| AU2015257289B2 (en) | 2014-05-05 | 2020-10-01 | Advanced Medical Solutions Israel (Sealantis) Ltd | Biological adhesives and sealants and methods of using the same |
| CN106573089A (zh) * | 2014-05-16 | 2017-04-19 | 奥创斯特公司 | 相转变制剂 |
| WO2018165327A1 (en) | 2017-03-08 | 2018-09-13 | Alafair Biosciences, Inc. | Hydrogel medium for the storage and preservation of tissue |
| CN113521398A (zh) * | 2021-08-10 | 2021-10-22 | 青岛琛蓝海洋生物工程有限公司 | 一种原位可注射防粘连凝胶及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57167919A (en) * | 1981-04-07 | 1982-10-16 | Hirozo Ohira | Preventing agent for intraperitoneal adhesion |
| CA1202904A (en) * | 1983-11-21 | 1986-04-08 | Brian G. Sparkes | Chitosan based wound dressing materials |
| DE3601132A1 (de) * | 1986-01-16 | 1987-07-23 | Christian Bannert | Verfahren zur behandlung der schleimhaut |
| US4948575A (en) * | 1989-01-24 | 1990-08-14 | Minnesota Mining And Manufacturing Company | Alginate hydrogel foam wound dressing |
| GB8911177D0 (en) * | 1989-05-16 | 1989-07-05 | Vilain Jean | Alginate gel pharmaceutical product |
| US5093319A (en) * | 1989-10-31 | 1992-03-03 | Pfizer Hospital Products Group, Inc. | Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions |
| US4994277A (en) * | 1989-10-31 | 1991-02-19 | Pfizer Hospital Products Group, Inc. | Use of xanthan gum for preventing adhesions |
-
1992
- 1992-06-30 US US07/906,953 patent/US5266326A/en not_active Expired - Fee Related
-
1993
- 1993-04-02 ES ES93908588T patent/ES2094537T3/es not_active Expired - Lifetime
- 1993-04-02 DK DK93908588.2T patent/DK0648122T3/da active
- 1993-04-02 AU AU39356/93A patent/AU671114B2/en not_active Ceased
- 1993-04-02 AT AT93908588T patent/ATE145331T1/de not_active IP Right Cessation
- 1993-04-02 EP EP93908588A patent/EP0648122B1/de not_active Expired - Lifetime
- 1993-04-02 JP JP6502325A patent/JPH07504682A/ja active Pending
- 1993-04-02 DE DE69306114T patent/DE69306114T2/de not_active Expired - Fee Related
- 1993-04-02 WO PCT/US1993/002814 patent/WO1994000134A1/en not_active Ceased
- 1993-04-02 CA CA002139311A patent/CA2139311A1/en not_active Abandoned
-
1996
- 1996-12-18 GR GR960403540T patent/GR3022093T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69306114D1 (de) | 1997-01-02 |
| DE69306114T2 (de) | 1997-03-13 |
| EP0648122A1 (de) | 1995-04-19 |
| ES2094537T3 (es) | 1997-01-16 |
| CA2139311A1 (en) | 1994-01-06 |
| DK0648122T3 (da) | 1996-12-09 |
| EP0648122B1 (de) | 1996-11-20 |
| JPH07504682A (ja) | 1995-05-25 |
| US5266326A (en) | 1993-11-30 |
| AU671114B2 (en) | 1996-08-15 |
| AU3935693A (en) | 1994-01-24 |
| WO1994000134A1 (en) | 1994-01-06 |
| GR3022093T3 (en) | 1997-03-31 |
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