ATE143266T1 - Komplexe und chelate des azithromycins als antiulcus-mittel - Google Patents

Komplexe und chelate des azithromycins als antiulcus-mittel

Info

Publication number
ATE143266T1
ATE143266T1 AT91103336T AT91103336T ATE143266T1 AT E143266 T1 ATE143266 T1 AT E143266T1 AT 91103336 T AT91103336 T AT 91103336T AT 91103336 T AT91103336 T AT 91103336T AT E143266 T1 ATE143266 T1 AT E143266T1
Authority
AT
Austria
Prior art keywords
chelates
complexes
azithromycin
antiulcus
agent
Prior art date
Application number
AT91103336T
Other languages
German (de)
English (en)
Inventor
Slobodan Djokic
Zlatko Vajtner
Hrvoje Krnjevic
Nevenka Lopotar
Lidija Kolacny-Babic
Original Assignee
Pliva Pharm & Chem Works
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Pharm & Chem Works filed Critical Pliva Pharm & Chem Works
Application granted granted Critical
Publication of ATE143266T1 publication Critical patent/ATE143266T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT91103336T 1990-03-07 1991-03-05 Komplexe und chelate des azithromycins als antiulcus-mittel ATE143266T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU45590A YU45590A (sh) 1990-03-07 1990-03-07 Novi kompleksi odnosno helati antibiotika s dvovalentnim i/ili trovalentnim metalima i postupci za njihovo dobijanje

Publications (1)

Publication Number Publication Date
ATE143266T1 true ATE143266T1 (de) 1996-10-15

Family

ID=25550003

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91103336T ATE143266T1 (de) 1990-03-07 1991-03-05 Komplexe und chelate des azithromycins als antiulcus-mittel

Country Status (20)

Country Link
US (1) US5498699A (enExample)
EP (1) EP0445743B1 (enExample)
JP (1) JP2731636B2 (enExample)
CN (2) CN1041166C (enExample)
AT (1) ATE143266T1 (enExample)
BG (1) BG61230B1 (enExample)
CA (1) CA2037663C (enExample)
CZ (1) CZ280181B6 (enExample)
DE (1) DE69122282T2 (enExample)
DK (1) DK0445743T3 (enExample)
ES (1) ES2094763T3 (enExample)
GR (1) GR3021947T3 (enExample)
HR (1) HRP940256B1 (enExample)
HU (2) HU209455B (enExample)
PL (1) PL166279B1 (enExample)
RO (1) RO107660B1 (enExample)
RU (2) RU2039060C1 (enExample)
SI (1) SI9010455B (enExample)
SK (1) SK279278B6 (enExample)
YU (1) YU45590A (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2064634C (en) * 1991-04-04 1998-08-04 James V. Heck 9-deoxo-8a-aza-8a-homoerythromycin a derivatives modified at the 4"- and8a-positions
GB9120131D0 (en) * 1991-09-20 1991-11-06 Glaxo Group Ltd Medicaments
TW271400B (enExample) * 1992-07-30 1996-03-01 Pfizer
GB9501560D0 (en) 1995-01-26 1995-03-15 Nycomed Imaging As Contrast agents
HUP9900428A2 (hu) * 1995-01-26 1999-06-28 Nycomed Imaging A/S Bizmutvegyületek, ezeket tartalmazó diagnosztikai kontrasztanyag, ennek alkalmazása és ezt tartalmazó gyógyászati készítmény
US5900410A (en) * 1996-08-27 1999-05-04 Hartmann; John F. Monotherapy of peptic ulcers and gastritis
US6861411B1 (en) 1997-12-02 2005-03-01 Pfizer, Inc. Method of treating eye infections with azithromycin
US6239113B1 (en) 1999-03-31 2001-05-29 Insite Vision, Incorporated Topical treatment or prevention of ocular infections
US7056893B2 (en) 1999-03-31 2006-06-06 Insite Vision, Inc. Topical treatment for prevention of ocular infections
HRP20010301A2 (en) * 2001-04-27 2001-12-31 Pliva D D New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases
SI1390377T1 (sl) 2001-05-22 2006-06-30 Pfizer Prod Inc Nova kristalna oblika azitromicina
OA12845A (en) * 2001-08-21 2006-09-15 Pfizer Prod Inc Single dose azithromycin for treating respiratory infections.
RU2283116C2 (ru) * 2002-05-27 2006-09-10 Курский государственный медицинский университет Способ увеличения выживаемости изолированного кожного лоскута "на ножке" у животных с пониженным антиоксидантным фоном
US7468428B2 (en) 2004-03-17 2008-12-23 App Pharmaceuticals, Llc Lyophilized azithromycin formulation
US20060046970A1 (en) * 2004-08-31 2006-03-02 Insite Vision Incorporated Topical otic compositions and methods of topical treatment of prevention of otic infections
EP1805134B1 (en) * 2004-10-25 2012-06-20 Paratek Pharmaceuticals, Inc. 4-aminotetracyclines and methods of use thereof
WO2008045507A2 (en) 2006-10-11 2008-04-17 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds for treatment of bacillus anthracis infections
CN104892694A (zh) * 2015-05-24 2015-09-09 广西师范学院 蔗糖硫酸酯铜类化合物及其制作方法和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862225A (en) * 1961-08-18 1975-01-21 Pfizer D-ring substituted tetracyclines
US3622627A (en) * 1967-09-13 1971-11-23 Pfizer 4-dedimethylaminatetracycline and 5a, 6-anhydro derivatives thereof
HU167946B (enExample) * 1973-04-16 1976-01-28
YU43006B (en) * 1981-03-06 1989-02-28 Pliva Pharm & Chem Works Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof
SG72632A1 (en) * 1985-04-18 2000-05-23 Procter & Gamble Treatment of non-ulcer dyspepsia with bismuth salts
EP0206625B1 (en) * 1985-06-13 1992-09-30 Barry James Dr. Marshall Compositions for the treatment of gastrointestinal disorders
IT1200774B (it) * 1985-10-10 1989-01-27 Pierrel Spa Procedimento di sentisi dell'amikacina
YU44599B (en) * 1986-09-12 1990-10-31 Pliva Pharm & Chem Works Process for preparing complex of n-methyl-11-aza-10-deoxo-10-dihydroeritromicine a and 11-aza-10-deoxo-10-dihydroeritromicine a with metals
HU198913B (en) * 1987-09-03 1989-12-28 Pliva Pharm & Chem Works Process for producing 10-dihydro-10-deoxo-11-aza-erythronolide a-derivatives and pharmaceutical compositions containing them as active components
WO1989003219A1 (en) * 1987-10-12 1989-04-20 Borody Thomas J Improved method for treatment of gastrointestinal disorders
US5246708A (en) * 1987-10-28 1993-09-21 Pro-Neuron, Inc. Methods for promoting wound healing with deoxyribonucleosides
ATE68476T1 (de) * 1989-04-03 1991-11-15 Ranbaxy Lab Ltd Verfahren zur herstellung von alpha-6deoxytetracyclinen.
US5348946A (en) * 1991-02-28 1994-09-20 Biochem Immunosystems, Inc. Heteroanthracycline antitumor analogs
MA28714B1 (fr) * 2005-12-15 2007-07-02 Green Technlology Sarl Une arabinogalactane proteine ayant la propriete d'absorber les graisses et le procede d'obtention de cette arabinogalactane proteine

Also Published As

Publication number Publication date
EP0445743A2 (en) 1991-09-11
CZ280181B6 (cs) 1995-11-15
SK279278B6 (sk) 1998-09-09
HUT56849A (en) 1991-10-28
DE69122282D1 (de) 1996-10-31
PL166279B1 (pl) 1995-04-28
CA2037663A1 (en) 1991-09-08
EP0445743B1 (en) 1996-09-25
HU209455B (en) 1994-06-28
RU2039061C1 (ru) 1995-07-09
JPH06184186A (ja) 1994-07-05
CS9100587A2 (en) 1991-10-15
GR3021947T3 (en) 1997-03-31
BG61230B1 (bg) 1997-03-31
SI9010455B (sl) 2000-04-30
SI9010455A (en) 1997-08-31
RO107660B1 (ro) 1993-12-30
BG93995A (bg) 1993-12-24
YU45590A (sh) 1992-07-20
CN1051560C (zh) 2000-04-19
HRP940256A2 (en) 1997-06-30
CA2037663C (en) 1999-01-19
HU211475A9 (en) 1995-11-28
HRP940256B1 (en) 1998-10-31
EP0445743A3 (en) 1992-10-07
CN1168891A (zh) 1997-12-31
DK0445743T3 (enExample) 1997-02-17
CN1054534A (zh) 1991-09-18
RU2039060C1 (ru) 1995-07-09
ES2094763T3 (es) 1997-02-01
JP2731636B2 (ja) 1998-03-25
HU910740D0 (en) 1991-09-30
US5498699A (en) 1996-03-12
CN1041166C (zh) 1998-12-16
DE69122282T2 (de) 1997-04-24

Similar Documents

Publication Publication Date Title
ATE143266T1 (de) Komplexe und chelate des azithromycins als antiulcus-mittel
NO173976C (no) Forbedret metallholdig diagnostisk middel
DE50102815D1 (de) Neue n-phenylpyrrolbisphosphanverbindungen und deren metallkomplexe
NO305078B1 (no) Heteroatomholdige ligander og metallkomplekser av disse, anvendelse av kompleksene og sett for fremstilling av dem
FI972287L (fi) Uudenlaisia polysubstituoituja DTPA-johdoksia ja niiden metallikomplekseja, kyseisiä komplekseja sisältäviä farmaseuttisia aineita, niiden käyttö diagnosoinnissa ja terapiassa sekä menetelmiä kyseisten kompleksinmuodostajien ja kompleksien valmistamiseksi ja menetelmiä kyseisten.
TR200103525T2 (tr) Bisiklik poliaminosit metal kompleksleri, bunları hazırlamak için yöntem ve bunların tıbbi görüntülemede kullanımı.
ES2181744T3 (es) Hidratos de paclitaxel cristalinos.
DE69807558D1 (de) Chelatkomplexe paramagnetischer Metalle mit niedriger Toxizität
DE58905201D1 (de) Mittel zur behandlung des parkinson-syndroms.
ATE140917T1 (de) Chelatbildende verbindungen, die eine ortho- bindende gruppe besitzen und ihre komplexe
DE69014619D1 (de) Ruthenium(iii)-komplexe als antineoplastische mittel.
ATE273702T1 (de) Eisenverbindungen, zusammensetzungen, herstellungsverfahren und verwendungen davon
ATE227137T1 (de) Liganden zur verbesserung der metallchelatbildungskinetik
ZA921717B (en) Chelates,their metal complexes as well as their use in diagnosis and treatment
ATE130304T1 (de) Neue alpha-glukosidaseinhibitoren.
GR3004570T3 (enExample)
DE69703373D1 (de) Chelierende Verbindungen, ihre Chelate mit paramagnetischen Metallen, ihre Herstellung und Verwendung
DE3851054D1 (de) Antitumor 6-sulfenamid, 6-sulfinamid und 6-sulfonamid-purine, purin-nukleoside, purin-nukleotide und verwandte verbindungen.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee