ATE137972T1 - Niedrig dosierte formulierung eines oralen antikoagulans/plättchen-aggregationsinhibitors - Google Patents

Niedrig dosierte formulierung eines oralen antikoagulans/plättchen-aggregationsinhibitors

Info

Publication number
ATE137972T1
ATE137972T1 AT90913060T AT90913060T ATE137972T1 AT E137972 T1 ATE137972 T1 AT E137972T1 AT 90913060 T AT90913060 T AT 90913060T AT 90913060 T AT90913060 T AT 90913060T AT E137972 T1 ATE137972 T1 AT E137972T1
Authority
AT
Austria
Prior art keywords
platele
low dose
oral anticoagulant
aggregation inhibitor
dose oral
Prior art date
Application number
AT90913060T
Other languages
English (en)
Inventor
William Joseph Addicks
Joseph A Mollica
Gary Howard Slatko
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Application granted granted Critical
Publication of ATE137972T1 publication Critical patent/ATE137972T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
AT90913060T 1989-09-18 1990-09-05 Niedrig dosierte formulierung eines oralen antikoagulans/plättchen-aggregationsinhibitors ATE137972T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/408,394 US5041430A (en) 1989-09-18 1989-09-18 Oral anticoagulant/platelet inhibitor low dose formulation

Publications (1)

Publication Number Publication Date
ATE137972T1 true ATE137972T1 (de) 1996-06-15

Family

ID=23616120

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90913060T ATE137972T1 (de) 1989-09-18 1990-09-05 Niedrig dosierte formulierung eines oralen antikoagulans/plättchen-aggregationsinhibitors

Country Status (22)

Country Link
US (1) US5041430A (de)
EP (1) EP0493408B1 (de)
JP (1) JPH05501109A (de)
KR (1) KR950008307B1 (de)
AT (1) ATE137972T1 (de)
AU (1) AU635881B2 (de)
CA (1) CA2065347A1 (de)
CZ (1) CZ454090A3 (de)
DE (1) DE69027036D1 (de)
FI (1) FI921134A (de)
GR (1) GR1001131B (de)
HU (1) HUT62488A (de)
IE (1) IE903356A1 (de)
IL (1) IL95721A (de)
LV (1) LV10050B (de)
MA (1) MA21953A1 (de)
MX (1) MX173727B (de)
NO (1) NO920946L (de)
NZ (1) NZ235337A (de)
PT (1) PT95343B (de)
WO (1) WO1991004031A1 (de)
ZA (1) ZA907431B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672585A (en) * 1990-04-06 1997-09-30 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5612311A (en) 1990-04-06 1997-03-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5780303A (en) * 1990-04-06 1998-07-14 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US6521594B1 (en) 1990-04-06 2003-02-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5635477A (en) * 1991-09-30 1997-06-03 The Dupont Merck Pharmaceutical Company Cyclic compounds useful as inhibitors of platelet glycoprotein IIB/IIIA
CA2100836C (en) * 1993-07-19 1998-02-03 Bernard Charles Sherman PHARMACEUTICAL COMPOSITION
EP0821587A4 (de) * 1995-04-19 1999-05-19 Lipoprotein Technologies Inc Mittel, kits und verfahren zur verabreichung von antilipämischen und gegen die blutplättchen-aggregation wirkenden arzneistoffen
US8022095B2 (en) * 1996-08-16 2011-09-20 Pozen, Inc. Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
US6121249A (en) * 1998-07-01 2000-09-19 Donald L. Weissman Treatment and prevention of cardiovascular diseases with help of aspirin, antioxidants, niacin, and certain B vitamins
IT1312088B1 (it) * 1999-04-21 2002-04-04 Altergon Sa Cerotto per uso topico contenente eparina e diclofenac.
US8173164B2 (en) * 1999-06-17 2012-05-08 Gruenenthal Gmbh Oral administration forms for administering a fixed tramadol and diclofenac combination
WO2002043806A2 (en) * 2000-12-01 2002-06-06 Rheologics, Inc In vivo delivery methods and compositions
WO2002079778A2 (en) * 2001-03-28 2002-10-10 Rheologics, Inc. In vivo delivery methods and compositions
US7691833B2 (en) * 2002-03-01 2010-04-06 Trustees Of Dartmouth College Compositions and methods for preventing sporadic neoplasia in colon
CA2512666A1 (en) * 2003-01-08 2004-07-29 Flacco-Nesselroad Family Trust Combination therapy for anticoagulation
CZ20032854A3 (cs) * 2003-10-17 2005-05-18 Pliva - Lachema A.S. Způsob přípravy dávkových jednotek pevné lékové formy obsahujících jako účinnou látku sodnou sůl warfarinu
CA2553156A1 (en) * 2003-10-20 2005-05-12 Teva Pharmaceutical Industries Ltd. Composition and dosage form for sustained effect of levodopa
SI21637A (sl) * 2003-12-23 2005-06-30 LEK farmacevtska dru�ba d.d. Farmacevtska oblika z nadzorovanim sproščanjem
US20060003000A1 (en) * 2004-07-01 2006-01-05 Lawrence Solomon Adhesively bonded dosage form
US7838031B2 (en) * 2004-05-21 2010-11-23 Lawrence Solomon Method of administering a partial dose using a segmented pharmaceutical tablet
WO2005112898A1 (en) * 2004-05-21 2005-12-01 Accu-Break Pharmaceuticals, Inc. Pharmaceutical tablets having a relatively inactive segment
US8758814B2 (en) 2004-10-08 2014-06-24 Mcneil-Ppc, Inc. Chewable enteric coated aspirin tablets
US8057820B2 (en) * 2004-10-08 2011-11-15 Mcneil-Ppc, Inc. Enteric coated aspirin granules comingled with binder
JP4613590B2 (ja) 2004-11-16 2011-01-19 セイコーエプソン株式会社 実装基板及び電子機器
US20100034878A1 (en) * 2006-12-19 2010-02-11 Bussey Henry I Combination of vitamin k and vitamin k antagonist such as r-isomer of warfarin, phenprocoumon or r-isomer of phenprocoumon as anticoagulant therapy
WO2008156691A1 (en) * 2007-06-19 2008-12-24 Duke University Anitcoagulants as antifouling agents
DE102008014237A1 (de) * 2008-03-14 2009-09-17 J. Rettenmaier & Söhne Gmbh + Co. Kg Direktverpressbares Tablettierhilfsmittel
JP5529404B2 (ja) * 2008-09-05 2014-06-25 東和薬品株式会社 アスピリン腸溶錠
WO2012060847A1 (en) 2010-11-07 2012-05-10 Targegen, Inc. Compositions and methods for treating myelofibrosis
LV14606B (lv) 2011-05-17 2013-01-20 Tetra, Sia Jauns XII faktora inhibitors
CZ304136B6 (cs) * 2012-06-27 2013-11-13 Veterinární a farmaceutická univerzita Brno, Farmaceutická fakulta Zpusob prípravy pevné lékové formy se sodnou solí warfarinu ve forme klathrátu izopropanolu
JP6304751B2 (ja) * 2014-03-24 2018-04-04 日新製薬株式会社 ワルファリン含有固形製剤及びその製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2265273A1 (en) * 1974-03-29 1975-10-24 Zootherap Laboratoires Anticoagulant-contg. rodenticidal compsn. - contg. (acetyl) salicyclic acid or salt as synergist
LU77353A1 (de) * 1977-05-16 1979-01-19
GB2038625B (en) * 1978-12-29 1983-01-12 Parcor Therapeutic composition having an antithrombotic and antiblood-platelet-aggregating activity
EP0001503B1 (de) * 1977-10-08 1981-01-07 Beecham Group Plc Antithrombotisch wirksame Präparate enthaltend Benzisothiazolone
SU1050708A1 (ru) * 1981-04-27 1983-10-30 Горьковский государственный медицинский институт им.С.М.Кирова Способ лечени гиперкоагул ции при коронарном атеросклерозе
US4444777A (en) * 1981-07-30 1984-04-24 Bristol-Myers Company Pharmaceutical compositions of anagrelide and sulfinpyrazone
DE3576119D1 (de) * 1984-07-21 1990-04-05 Hoechst Ag Kombinationspraeparat aus pyrimido-pyrimidinen und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung.

Also Published As

Publication number Publication date
ZA907431B (en) 1992-05-27
LV10050B (en) 1995-02-20
PT95343B (pt) 1998-06-30
IL95721A0 (en) 1991-06-30
HUT62488A (en) 1993-05-28
NO920946D0 (no) 1992-03-11
AU6330690A (en) 1991-04-18
GR900100702A (en) 1992-01-20
LV10050A (lv) 1994-05-10
KR920703046A (ko) 1992-12-17
FI921134A0 (fi) 1992-03-17
MA21953A1 (fr) 1991-04-01
GR1001131B (el) 1993-04-28
WO1991004031A1 (en) 1991-04-04
CA2065347A1 (en) 1991-03-19
IL95721A (en) 1995-07-31
AU635881B2 (en) 1993-04-01
KR950008307B1 (ko) 1995-07-27
MX173727B (es) 1994-03-24
FI921134A (fi) 1992-03-17
DE69027036D1 (de) 1996-06-20
PT95343A (pt) 1991-08-14
NZ235337A (en) 1993-05-26
NO920946L (no) 1992-03-11
JPH05501109A (ja) 1993-03-04
IE903356A1 (en) 1991-04-10
EP0493408A1 (de) 1992-07-08
EP0493408A4 (en) 1992-10-07
US5041430A (en) 1991-08-20
CZ454090A3 (en) 1996-11-13
EP0493408B1 (de) 1996-05-15

Similar Documents

Publication Publication Date Title
ATE137972T1 (de) Niedrig dosierte formulierung eines oralen antikoagulans/plättchen-aggregationsinhibitors
NO302366B1 (no) 4-merkaptoacetylamino-£2|benzazepinon(3)-derivater, og farmasöytisk preparat
MX9205432A (es) Compuestos inhibidores de la biosintesis de leucotrienos y composicion farmaceutica que los contiene.
AR042345A2 (es) Un procedimiento para la preparacion de una composicion farmaceutica para el tratamiento de aterosclerosis que contiene 8.9 - dehidroesterona o sus sales de la misma
MX9206851A (es) Sales organicas de n,n'-diacetil cistina, proceso para su preparacion y composicion farmaceutica que las contiene.
ES511433A0 (es) "procedimiento de preparacion de productos utiles particularmente en medicamentos utilizables para el tratamiento de melanomas".
PT81885A (de) Synergistische kombination von flupirtin und nichtsteroidalen antiphlogistika
FI793261A (fi) Farmaceutisk komposition som innehaoller 3,4-dihydro-3-oxo-2-kinoxaliner
MX9202763A (es) Nuevos derivados de 2-(1-piperazinil)-4-fenil-cicloalcanopiridina y composicion farmaceutica que los contiene.
ATE6358T1 (de) 2-aminotetralin-verbindungen und pharmazeutische zusammensetzungen mit zentraler alpha1-agonist- wirksamkeit.
MX9203460A (es) Nuevos analogos cc-1065 que tienen dos subunidades cpi.
MX3375A (es) Procedimiento de preparacion de nuevas benzamidas y sus sales, producto obtenido y composicion farmaceutica que lo incluye.
IT8721687A0 (it) Derivati dell'ossima della 1,2,5,6-tetraidropiridin-3-carbossa ldeide, loro procedimento di preparazione e loro impiego come sostanze medicinali.
KR880001293A (ko) 안티트롬빈 작용을 가지는 활성 물질 조합
FR2707455B1 (fr) Empêchement de la reproduction des insectes xylophages, moyens pour le traitement préventif du matériau bois mis en Óoeuvre.
DE3851323D1 (de) Eutektische Zusammensetzung von zwei Nitrazapentanderivaten.
KR920700037A (ko) 치료에 유용한 혈소판 항-응집 효과를 갖는 조성물
ES264630Y (es) Una estanteria, en especial para la exhibicion de zapatos o similares.
MX19466A (es) Procedimiento para la preparacion de derivados isomericos de los 2',3'-dideoxinucleosidos y productos obtenidos mediante el mismo.
IT8819258A0 (it) Composizioni iniettabili per il trattamento delle encefalopatie epatiche.
AR240016A1 (es) Procedimiento de preparacion de una composicion para el tratamiento de flebectasias.
IT8423850A0 (it) Apparecchiatura per l'annullamento dei talloncini farmaceutici, apposti sulle ricette mediche, eper il confezionamento delle stesse e relativo procedimento.
AR240472Q (es) Un procedimiento para la preparaciond e una composicon lubricante de derivados carboxilicos.
MX21671A (es) Procedimiento para la preparacion de derivados de aminoalcoxibenceno substituido y productos obtenidos mediante el mismo.
MX9203372A (es) Composiciones farmaceuticas de buspirona y sales de la misma, de aplicacion oral.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties