ATE129693T1 - Verfahren zur herstellung von s(+)-6-methoxy- alpha-methyl-2-naphthalin-essigsäure. - Google Patents
Verfahren zur herstellung von s(+)-6-methoxy- alpha-methyl-2-naphthalin-essigsäure.Info
- Publication number
- ATE129693T1 ATE129693T1 AT91201935T AT91201935T ATE129693T1 AT E129693 T1 ATE129693 T1 AT E129693T1 AT 91201935 T AT91201935 T AT 91201935T AT 91201935 T AT91201935 T AT 91201935T AT E129693 T1 ATE129693 T1 AT E129693T1
- Authority
- AT
- Austria
- Prior art keywords
- methoxy
- alpha
- methyl
- naphthalene
- acetic acid
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- CMWTZPSULFXXJA-UHFFFAOYSA-N Naproxen Natural products C1=C(C(C)C(O)=O)C=CC2=CC(OC)=CC=C21 CMWTZPSULFXXJA-UHFFFAOYSA-N 0.000 abstract 3
- JCBPETKZIGVZRE-SCSAIBSYSA-N (2r)-2-aminobutan-1-ol Chemical compound CC[C@@H](N)CO JCBPETKZIGVZRE-SCSAIBSYSA-N 0.000 abstract 2
- 239000013078 crystal Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL9001703A NL9001703A (nl) | 1990-07-27 | 1990-07-27 | Werkwijze voor de bereiding van s(+)-6-methoxy-alfa-methyl-2-naftaleen-azijnzuur. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE129693T1 true ATE129693T1 (de) | 1995-11-15 |
Family
ID=19857478
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91201935T ATE129693T1 (de) | 1990-07-27 | 1991-07-24 | Verfahren zur herstellung von s(+)-6-methoxy- alpha-methyl-2-naphthalin-essigsäure. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5200555A (de) |
| EP (1) | EP0468592B1 (de) |
| JP (1) | JPH04234342A (de) |
| AT (1) | ATE129693T1 (de) |
| DE (1) | DE69114202D1 (de) |
| NL (1) | NL9001703A (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2061403B1 (es) * | 1993-04-16 | 1995-06-16 | Medichem Sa | Procedimiento de obtencion del acido d-(-) -3 acetiltio-2- metilpropionico. |
| IT1277102B1 (it) * | 1995-12-19 | 1997-11-04 | Farchemia Srl | Procedimento per la scissione dell'acido 6-metossi-alfa-metil-2- naftalenacetico racemico nei suoi enantiomeri |
| DE19624604A1 (de) * | 1996-06-20 | 1998-01-02 | Hoechst Ag | Verfahren zur Herstellung chiraler, nicht racemischer (4-Aryl-2,5-dioxoimidazolidin-1-yl)essigsäuren |
| US6706883B1 (en) * | 1998-07-02 | 2004-03-16 | Schering Corporation | Process for producing (8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-B]pyridin-11-YL)-1-piperdine |
| US6436990B1 (en) | 1999-10-27 | 2002-08-20 | Nobex Corporation | 6-methoxy-2-naphthylacetic acid prodrugs |
| TWI262791B (en) | 1999-10-27 | 2006-10-01 | Nobex Corp | 6-methoxy-2-naphthylacetic acid prodrugs |
| US6552078B2 (en) | 1999-10-27 | 2003-04-22 | Nobex Corp | 6-methoxy-2-naphthylacetic acid prodrugs |
| SI1348684T1 (sl) | 2003-04-09 | 2006-06-30 | Servier Lab | Nov postopek sinteze (2s)-indolin-2-karboksilne kisline in uporaba pri sintezi perindoprila |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3686183A (en) * | 1969-03-24 | 1972-08-22 | Syntex Corp | Preparation of optical isomers of arylalkylacetic acids |
| JPS5822139B2 (ja) * | 1979-12-28 | 1983-05-06 | 日清製粉株式会社 | ｄｌ−２−（６−メトキシ−２−ナフチル）−プロピオン酸の光学分割法 |
| IT1164319B (it) * | 1983-07-27 | 1987-04-08 | Blaschim Spa | Procedimento per la risoluzione dell'acido (+-)2-(6'-metossi-2'-naftil)-propionico |
| JPH0684332B2 (ja) * | 1985-06-20 | 1994-10-26 | 住友化学工業株式会社 | ａ−イソプロピル−ｐ−クロルフエニル酢酸の光学分割法 |
| DE3824353A1 (de) * | 1988-07-19 | 1990-01-25 | Paz Arzneimittelentwicklung | Verfahren zur trennung von gemischen enantiomerer arylpropionsaeuren |
| IT1235650B (it) * | 1988-12-22 | 1992-09-18 | Zambon Spa | Processo per la preparazione dell'estere metilico dell'acido s(+)-2-5-bromo-6-metossi-2-naftil)-propionico per cristallizzazione preferenziale |
-
1990
- 1990-07-27 NL NL9001703A patent/NL9001703A/nl not_active Application Discontinuation
-
1991
- 1991-07-23 US US07/734,598 patent/US5200555A/en not_active Expired - Fee Related
- 1991-07-24 EP EP91201935A patent/EP0468592B1/de not_active Expired - Lifetime
- 1991-07-24 DE DE69114202T patent/DE69114202D1/de not_active Expired - Lifetime
- 1991-07-24 AT AT91201935T patent/ATE129693T1/de not_active IP Right Cessation
- 1991-07-26 JP JP3186729A patent/JPH04234342A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0468592A2 (de) | 1992-01-29 |
| JPH04234342A (ja) | 1992-08-24 |
| NL9001703A (nl) | 1992-02-17 |
| EP0468592A3 (en) | 1992-11-25 |
| US5200555A (en) | 1993-04-06 |
| DE69114202D1 (de) | 1995-12-07 |
| EP0468592B1 (de) | 1995-11-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |