ATE129526T1 - Wasserunlösbares reagenz, nukleinsäure-sonde, testsatz und verfahren zur diagnose und isolierung. - Google Patents

Wasserunlösbares reagenz, nukleinsäure-sonde, testsatz und verfahren zur diagnose und isolierung.

Info

Publication number
ATE129526T1
ATE129526T1 AT91200082T AT91200082T ATE129526T1 AT E129526 T1 ATE129526 T1 AT E129526T1 AT 91200082 T AT91200082 T AT 91200082T AT 91200082 T AT91200082 T AT 91200082T AT E129526 T1 ATE129526 T1 AT E129526T1
Authority
AT
Austria
Prior art keywords
nucleic acid
water
diagnosis
acid probe
isolation
Prior art date
Application number
AT91200082T
Other languages
English (en)
Inventor
Harold Chester Iii C O Warren
Street State
John Bruce C O Eastman Findlay
Marlene Marie C O Eastman King
Original Assignee
Johnson & Johnson Clin Diag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson Clin Diag filed Critical Johnson & Johnson Clin Diag
Application granted granted Critical
Publication of ATE129526T1 publication Critical patent/ATE129526T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • AIDS & HIV (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT91200082T 1990-01-26 1991-01-17 Wasserunlösbares reagenz, nukleinsäure-sonde, testsatz und verfahren zur diagnose und isolierung. ATE129526T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47116890A 1990-01-26 1990-01-26

Publications (1)

Publication Number Publication Date
ATE129526T1 true ATE129526T1 (de) 1995-11-15

Family

ID=23870526

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91200082T ATE129526T1 (de) 1990-01-26 1991-01-17 Wasserunlösbares reagenz, nukleinsäure-sonde, testsatz und verfahren zur diagnose und isolierung.

Country Status (10)

Country Link
US (1) US5328825A (de)
EP (1) EP0439222B1 (de)
JP (1) JPH0746999A (de)
KR (1) KR910014701A (de)
AT (1) ATE129526T1 (de)
CA (1) CA2031659A1 (de)
DE (1) DE69114023T2 (de)
FI (1) FI910396A (de)
HK (1) HK38196A (de)
IE (1) IE910264A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232829A (en) * 1989-09-29 1993-08-03 Hoffmann-La Roche Inc. Detection of chlamydia trachomatis by polymerase chain reaction using biotin labelled lina primers and capture probes
US5663318A (en) * 1991-03-01 1997-09-02 Pegg; Randall Kevin Assay preparation containing capture and detection polynucleotides covalently bound to substrates with a heterobifunctional crosslinking agent
FR2677039B1 (fr) * 1991-05-31 1994-09-09 Cis Bio Int Oligonucleotides, utilisables comme reactifs pour la detection in vitro des infections a retrovirus de type hiv et procede de detection de retrovirus de type hiv.
FR2680005B1 (fr) * 1991-08-01 1994-09-02 Coletica Utilisation de collagene comme support solide de fixation d'un capteur capable de reagir specifiquement avec un element a detecter dans un milieu biologique, reactif et procede de mise en óoeuvre.
US5648208A (en) * 1991-08-01 1997-07-15 Coletica Use of a collagen as solid binding substrate for a ligand capable of reacting specifically with an element to be detected in a biological medium, reactant and implementation
US5747244A (en) * 1991-12-23 1998-05-05 Chiron Corporation Nucleic acid probes immobilized on polystyrene surfaces
US5679510A (en) * 1993-04-27 1997-10-21 Hybridon, Inc. Quantitative detection of specific nucleic acid sequences using lambdoid bacteriophages linked by oligonucleotides to solid support
US5591580A (en) * 1994-03-31 1997-01-07 Johnson & Johnson Clinical Diagnostics, Inc. Method, test element and test kit for semi-quantitative detection of target nucleic acid
US5622822A (en) 1994-09-13 1997-04-22 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using polyethyleneimine and an anionic phosphate ester surfactant and amplification of same
US5705366A (en) 1994-09-15 1998-01-06 Johnson & Johnson Clinical Diagnostics, Inc. Coamplification of target nucleic acids using volume exclusion agent in reaction composition, test kit and test device useful therefor
US5582988A (en) 1994-09-15 1996-12-10 Johnson & Johnson Clinical Diagnostics, Inc. Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same
US5989813A (en) * 1995-07-13 1999-11-23 Molecular Innovations, Inc. Detection of amplified nucleic acid sequences using bifunctional haptenization and dyed microparticles
JPH11509100A (ja) * 1995-07-13 1999-08-17 イムノロジカル アソシエーツ オブ デンバー 核酸抽出、増幅および検出を統合する自己充足装置
ZA9610721B (en) 1995-12-21 1998-06-19 Cornell Res Foundation Inc Grapevine leafroll virus proteins and their uses.
ZA984232B (en) 1997-05-20 1998-12-01 Cornell Res Foundation Inc Grapevine leafroll virus type 2 proteins coding sequences and methods
US6093544A (en) * 1997-05-20 2000-07-25 Cornell Research Foundation, Inc. Rupestris stem pitting associated virus nucleic acids, proteins, and their uses
US6326489B1 (en) 1997-08-05 2001-12-04 Howard Hughes Medical Institute Surface-bound, bimolecular, double-stranded DNA arrays
US6511803B1 (en) * 1997-10-10 2003-01-28 President And Fellows Of Harvard College Replica amplification of nucleic acid arrays
EP1021558A1 (de) 1997-10-10 2000-07-26 President And Fellows Of Harvard College Oberflächengebundene, doppelsträngige dna-protein-arrays
AU737174B2 (en) 1997-10-10 2001-08-09 President & Fellows Of Harvard College Replica amplification of nucleic acid arrays
US6485944B1 (en) 1997-10-10 2002-11-26 President And Fellows Of Harvard College Replica amplification of nucleic acid arrays
EP0967218A1 (de) * 1998-05-26 1999-12-29 Academisch Ziekenhuis Bij De Universiteit Van Amsterdam Silica-Guanidiniumthiocyanat-DNS-Isolierung die Casein gebraucht
CA2370122C (en) 1999-05-04 2011-04-26 Ortho-Clinical Diagnostics, Inc. Rapid and efficient capture of dna from sample without using cell lysing reagent
JP4919568B2 (ja) 1999-10-22 2012-04-18 ピーエイチアールアイ プロパティーズ,インコーポレイテッド 短い配列の変異体を検出するためのアッセイ
AU7955800A (en) * 1999-10-25 2001-05-08 Wakunaga Pharmaceutical Co., Ltd Method of detecting target nucleic acid
US7262006B1 (en) 2000-05-01 2007-08-28 Ortho-Clinical Diagnostics, Inc. Rapid and efficient capture of DNA from sample without using cell lysing reagent
GB2363381B (en) * 2000-06-12 2004-11-24 Cambridge Molecular Tech Solution
GB0016836D0 (en) * 2000-07-07 2000-08-30 Lee Helen Improved dipstick assays (1)
US20040126900A1 (en) * 2001-04-13 2004-07-01 Barry Stephen E High affinity peptide- containing nanoparticles
JP2002333446A (ja) * 2001-05-09 2002-11-22 Fuji Photo Film Co Ltd 生物学的素材チップ
US20100105024A1 (en) * 2008-01-14 2010-04-29 Transgenex Nanobiotech, Inc. Rapid test including genetic sequence probe

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
CA1180647A (en) * 1981-07-17 1985-01-08 Cavit Akin Light-emitting polynucleotide hybridization diagnostic method
JPS59224565A (ja) * 1983-04-28 1984-12-17 Morinaga Milk Ind Co Ltd 抗原検出用試薬
US4713326A (en) * 1983-07-05 1987-12-15 Molecular Diagnostics, Inc. Coupling of nucleic acids to solid support by photochemical methods
US4582810A (en) * 1983-09-30 1986-04-15 Becton, Dickinson And Company Immuno-agglutination particle suspensions
US4748111A (en) * 1984-03-12 1988-05-31 Molecular Diagnostics, Inc. Nucleic acid-protein conjugate used in immunoassay
US4775619A (en) * 1984-10-16 1988-10-04 Chiron Corporation Polynucleotide determination with selectable cleavage sites
GB8507706D0 (en) * 1985-03-25 1985-05-01 Genetics Int Inc Magnetic nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
CA1308372C (en) * 1986-08-11 1992-10-06 Geneva Ruth Davis Nucleic acid probe sandwich assay methods and compositions
US4812414A (en) * 1987-09-18 1989-03-14 Eastman Kodak Company Immunoreactive reagent particles having tracer, receptor molecules and protein of pI less than 6
US4828978A (en) * 1987-09-18 1989-05-09 Eastman Kodak Company Agglutination reagent and method of preparing same
JPH07107537B2 (ja) * 1987-08-03 1995-11-15 イーストマン コダック カンパニー アビジン−及びビオチン−固定試薬,分析要素並びにその使用法

Also Published As

Publication number Publication date
IE910264A1 (en) 1991-07-31
FI910396A0 (fi) 1991-01-25
JPH0746999A (ja) 1995-02-21
US5328825A (en) 1994-07-12
EP0439222A3 (en) 1991-09-18
HK38196A (en) 1996-03-15
DE69114023D1 (de) 1995-11-30
EP0439222B1 (de) 1995-10-25
FI910396A (fi) 1991-07-27
EP0439222A2 (de) 1991-07-31
KR910014701A (ko) 1991-08-31
CA2031659A1 (en) 1991-07-27
DE69114023T2 (de) 1996-04-18

Similar Documents

Publication Publication Date Title
ATE129526T1 (de) Wasserunlösbares reagenz, nukleinsäure-sonde, testsatz und verfahren zur diagnose und isolierung.
ATE351923T1 (de) Diagnostische methode zur identifizierung von fötaler dna in einer maternalen probe
DE69032410T2 (de) Vorrichtung zur behandlung biologischer proben für die analyse von nukleinsäuren
DE69031984D1 (de) Ein nichtinvasives verfahren zur trennung und zum nachweis von fetaler dna
DE3750774D1 (de) Chaotropisches verfahren zur schätzung von nukleinen säuren in einer biologischen probe.
DE3486124D1 (de) Verfahren und strukturen in welchen chemisch markierte, nichtradioaktive polynucleotidesonden benutzt werden.
DE69535240D1 (de) Zusammensetzungen und Verfahren für die gleichzeitige Detektion und Quantifizierung von einer Mehrheit spezifischer Nuklein Säure Sequenzen
ATE180570T1 (de) Verfahren und vorrichtung zur herstellung von mikromatrizen für biologische proben
DE68926238D1 (de) Dns-analyse verfahren mit genamplifikation und magnetischen teilchen
ATE37551T1 (de) Sonde, die eine nukleinsaeure enthaelt und die durch spezifische antikoerper erkennbar ist, und deren anwendung zum nachweisen und charakterisieren einer homologen dns-sequenz.
DE3578349D1 (de) Hybridisierungstest fuer nukleinsaeure mittels anwendung von nachweisbaren anti-hybridantikoerpern.
EP0353985A3 (de) Nukleinsäureprobe zur Detektion von Neisseria gonorrhoea
DE69807293D1 (de) Multiplex-PCR zum Nachweis von Infektionen verursacht durch Mycobacterium Avium Komplex
AU1010688A (en) Diagnostic assays using nucleic acid probes
Katz et al. Colorimetric diagnosis of prolonged bluetongue viremia in sheep, using an enzyme-linked oligonucleotide sorbent assay of amplified viral nucleic acids
EP0305145A3 (de) Verfahren und Sonden zur Bestimmung von Nukleinsäuren
DE60219813D1 (de) Test-streife-probesystem und verfahren zur nachweis von spezifischen nukleinsäuresequenzen
ATE78301T1 (de) Molekulare genetische sonde und verfahren zu ihrer herstellung, testmethode und satz in denen diese molekulare genetische sonde gebraucht wird.
DE69129192T2 (de) Verfahren und reagenzien für die karakterisierung von hla-drbeta-dns
ATE147789T1 (de) Verfahren und vorrichtung zur ausführung biochemischer reaktionen
DE69022362D1 (de) Nukleinsäuresonden für die detektion von neisseria gonorrhoeae.
ES8801375A1 (es) Un metodo para determinar una secuencia polinucleotidica particular presente en un virus o celula
DE69019770D1 (de) Verfahren zur Reinigung, Vervielfachung und zum Nachweis einer Nukleinsäure.
DE69026006D1 (de) Enzymatisches Verfahren zur Bestimmung der Analyt-Konzentration
ATE133205T1 (de) Diagnoseverfahren für infektionskrankheiten sowie verfahren zum nachweis und identifizierung von mikroorganismen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties