ATE126807T1 - Glykopeptid-antibiotika. - Google Patents

Glykopeptid-antibiotika.

Info

Publication number
ATE126807T1
ATE126807T1 AT89310745T AT89310745T ATE126807T1 AT E126807 T1 ATE126807 T1 AT E126807T1 AT 89310745 T AT89310745 T AT 89310745T AT 89310745 T AT89310745 T AT 89310745T AT E126807 T1 ATE126807 T1 AT E126807T1
Authority
AT
Austria
Prior art keywords
vancosaminyl
epi
alpha
disaccharide
group
Prior art date
Application number
AT89310745T
Other languages
English (en)
Inventor
Manuel Debono
Robert Michael Molloy Sr
Ramakrishnan Nagarajan
Amelia Apolinaria Schabel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE126807T1 publication Critical patent/ATE126807T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT89310745T 1988-10-19 1989-10-19 Glykopeptid-antibiotika. ATE126807T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25967888A 1988-10-19 1988-10-19

Publications (1)

Publication Number Publication Date
ATE126807T1 true ATE126807T1 (de) 1995-09-15

Family

ID=22985922

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89310745T ATE126807T1 (de) 1988-10-19 1989-10-19 Glykopeptid-antibiotika.

Country Status (8)

Country Link
US (1) US6111067A (de)
EP (1) EP0365319B1 (de)
JP (1) JP2854343B2 (de)
AT (1) ATE126807T1 (de)
CA (1) CA1339808C (de)
DE (1) DE68923928T2 (de)
ES (1) ES2077584T3 (de)
GR (1) GR3017211T3 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2145609C1 (ru) * 1994-01-28 2000-02-20 Эли Лилли Энд Компани Производные гликопептида или их соли, способ получения, фармацевтическая композиция
US5840684A (en) * 1994-01-28 1998-11-24 Eli Lilly And Company Glycopeptide antibiotic derivatives
ES2224173T3 (es) * 1995-07-05 2005-03-01 Aventis Bulk S.P.A. Purificacion de antibioticos dalbaheptidos por enfoque isoelectrico.
US5919756A (en) * 1996-06-28 1999-07-06 Eli Lilly And Company Amides
CA2497159A1 (en) * 2002-08-30 2004-03-11 K.U. Leuven Research And Development Glycopeptide antibiotic and semisynthetic derivatives thereof and their use as antiviral agents
US7632918B2 (en) 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
GB2449156B8 (en) * 2007-05-08 2010-06-02 Lead Therapeutics Inc Semi-synthetic glycopeptides with antibacterial activity.
CN101928331B (zh) * 2009-06-26 2014-05-28 上海来益生物药物研究开发中心有限责任公司 一种化合物及其应用
CN102690330B (zh) * 2011-03-23 2014-10-08 浙江医药股份有限公司新昌制药厂 三取代糖肽类衍生物及药物组合物、以及其制备方法和用途
US11174288B2 (en) 2016-12-06 2021-11-16 Northeastern University Heparin-binding cationic peptide self-assembling peptide amphiphiles useful against drug-resistant bacteria

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029769A (en) * 1976-05-24 1977-06-14 Eli Lilly And Company Antibiotic A-35512B aglycone
US4322343A (en) * 1980-12-18 1982-03-30 Eli Lilly And Company Pseudo-aglycone of actaplanin
US4552701A (en) * 1984-04-16 1985-11-12 Eli Lilly And Company Glycopeptide antibiotics and process of preparation
US4946941A (en) * 1986-01-24 1990-08-07 Shionogi & Co., Ltd. Novel glycopeptide antibiotics
JPS62174099A (ja) * 1986-01-24 1987-07-30 Shionogi & Co Ltd 新規グリコペプチド系抗生物質ｐａ−４２８６７−ａおよびｐａ−４２８６７−ｂとその製造方法
EG18377A (en) * 1986-09-19 1993-04-30 Lilly Co Eli Process for preparing glycopeptide antibiotics
IE873523L (en) * 1986-12-30 1988-06-30 Memorex Corp Glycosylated glycopeptides
US5071749A (en) * 1987-04-16 1991-12-10 Shionogi & Co., Ltd. Glycopetide antibiotic pa-45052-b

Also Published As

Publication number Publication date
EP0365319A3 (en) 1990-10-03
EP0365319B1 (de) 1995-08-23
JPH02209893A (ja) 1990-08-21
JP2854343B2 (ja) 1999-02-03
US6111067A (en) 2000-08-29
EP0365319A2 (de) 1990-04-25
GR3017211T3 (en) 1995-11-30
ES2077584T3 (es) 1995-12-01
DE68923928T2 (de) 1996-02-08
DE68923928D1 (de) 1995-09-28
CA1339808C (en) 1998-04-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time