ATE126539T1 - Verfahren zur herstellung von vancomycin. - Google Patents

Verfahren zur herstellung von vancomycin.

Info

Publication number
ATE126539T1
ATE126539T1 AT90917220T AT90917220T ATE126539T1 AT E126539 T1 ATE126539 T1 AT E126539T1 AT 90917220 T AT90917220 T AT 90917220T AT 90917220 T AT90917220 T AT 90917220T AT E126539 T1 ATE126539 T1 AT E126539T1
Authority
AT
Austria
Prior art keywords
pct
fermentation
micropolyspora
ncaim
sec
Prior art date
Application number
AT90917220T
Other languages
English (en)
Inventor
Mariann Nagy
Miklus Jarai
Istvan Financsek
Ilona Varga
Geza Kocsis
Viola Muri
Andras Andrasi
Laszlu Kegl
Gabriella Zlatos
Laszlone Szoeke
Endre Kollar
Agnes Udvardy
Mihaly Garamvoelgyi
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Application granted granted Critical
Publication of ATE126539T1 publication Critical patent/ATE126539T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/867—Micromonospora

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Paper (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
AT90917220T 1989-11-27 1990-11-27 Verfahren zur herstellung von vancomycin. ATE126539T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU896184A HU205971B (en) 1989-11-27 1989-11-27 Process for producing vancomycin

Publications (1)

Publication Number Publication Date
ATE126539T1 true ATE126539T1 (de) 1995-09-15

Family

ID=10971323

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90917220T ATE126539T1 (de) 1989-11-27 1990-11-27 Verfahren zur herstellung von vancomycin.

Country Status (17)

Country Link
US (1) US5223413A (de)
EP (1) EP0455772B1 (de)
JP (1) JP2577133B2 (de)
KR (1) KR920701462A (de)
AT (1) ATE126539T1 (de)
AU (1) AU647757B2 (de)
BR (1) BR9007082A (de)
CA (1) CA2045483A1 (de)
DE (1) DE69021716T2 (de)
DK (1) DK0455772T3 (de)
ES (1) ES2075903T3 (de)
FI (1) FI102388B1 (de)
GR (1) GR1000960B (de)
HU (1) HU205971B (de)
NO (1) NO180382C (de)
WO (1) WO1991008300A1 (de)
ZA (1) ZA909528B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI9500039B (sl) * 1995-02-07 2002-02-28 Lek, Nov kombiniran postopek čiščenja Vankomicin hidroklorida
KR100419707B1 (ko) * 1995-12-29 2004-06-12 씨제이 주식회사 분취용 역상 고압 액체 크로마토그래피를 이용한반코마이신의 정제방법
KR100385152B1 (ko) * 2001-03-14 2003-05-23 씨제이 주식회사 카프레오마이신의 정제방법
TWI233932B (en) 2001-08-24 2005-06-11 Theravance Inc Process for purifying glycopeptide phosphonate derivatives
KR100554481B1 (ko) * 2004-06-30 2006-03-03 씨제이 주식회사 반코마이신 염산염의 정제방법
PL1805211T3 (pl) * 2004-10-27 2009-09-30 Xellia Pharmaceuticals Aps Oczyszczanie glikopeptydów
EP1798237A1 (de) * 2005-12-16 2007-06-20 Pharmatex Italia Srl Prozess zur Reinigung von Makrolid-Antibiotika
GB0814830D0 (en) * 2008-08-13 2008-09-17 Univ Cardiff Antimicrobial agent and method for the production thereof
KR101101663B1 (ko) 2009-01-13 2011-12-30 (주) 제노텍 반코마이신 습체의 정제방법
CN104610434B (zh) * 2013-11-01 2019-06-07 浙江医药股份有限公司新昌制药厂 一种盐酸万古霉素的分离纯化方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3067099A (en) * 1955-09-16 1962-12-04 Lilly Co Eli Vancomycin and method for its preparation
US4400753A (en) 1981-06-19 1983-08-23 International Business Machines Corporation Universal magnetic recording disk cartridge
JPS58194689A (ja) * 1982-05-08 1983-11-12 Mitsui Eng & Shipbuild Co Ltd 船舶用プロペラの製造方法
US4549925A (en) * 1982-11-22 1985-10-29 King Instrument Corporation Splicer plunger assembly
RO87735A2 (ro) * 1982-12-20 1985-10-31 Eli Lilly And Co,Us Procedeu de obtinere a antibioticului a 51568 cu structura gliceproteica
US4558009A (en) * 1982-12-20 1985-12-10 Eli Lilly And Company Process for producing antibiotic A-51568 by fermentation and microorganism
US4667024A (en) 1983-07-13 1987-05-19 Smithkline Beckman Corporation Process for the preparation of purified vancomycin class antibiotics
US4558008A (en) * 1983-12-13 1985-12-10 Eli Lilly And Company Process for production of A-51568B antibiotic
US4548924A (en) * 1984-04-16 1985-10-22 Eli Lilly And Company Antibiotics M43B and M43C, pharmaceutical composition and method of use
US4548925A (en) * 1984-04-16 1985-10-22 Eli Lilly And Company Antibiotic M43A, pharmaceutical composition and method of use
JPH0662674B2 (ja) * 1985-01-11 1994-08-17 三共株式会社 抗生物質クロロポリスポリンｂまたはｃ
JPS61214694A (ja) * 1985-03-18 1986-09-24 インタ−ナショナル　ビジネス　マシ−ンズ　コ−ポレ−ション データ伝送のスイッチング装置
GB8600952D0 (en) * 1986-01-16 1986-02-19 Glaxo Group Ltd Antibiotic production
US4946941A (en) * 1986-01-24 1990-08-07 Shionogi & Co., Ltd. Novel glycopeptide antibiotics
GB8608798D0 (en) * 1986-04-11 1986-05-14 Lepetit Spa Recovery of glycopeptide antibiotics from aqueous solutions
EG18377A (en) * 1986-09-19 1993-04-30 Lilly Co Eli Process for preparing glycopeptide antibiotics
US4845194A (en) * 1987-02-27 1989-07-04 Eli Lilly And Company Glycopeptide recovery process

Also Published As

Publication number Publication date
DK0455772T3 (da) 1995-09-18
US5223413A (en) 1993-06-29
GR900100826A (en) 1992-04-17
JPH05501358A (ja) 1993-03-18
DE69021716D1 (de) 1995-09-21
NO180382B (no) 1996-12-30
WO1991008300A1 (en) 1991-06-13
FI102388B (fi) 1998-11-30
ES2075903T3 (es) 1995-10-16
HU896184D0 (en) 1990-02-28
HU205971B (en) 1992-07-28
NO912832L (no) 1991-09-24
NO912832D0 (no) 1991-07-19
AU647757B2 (en) 1994-03-31
FI913586A0 (fi) 1991-07-26
EP0455772B1 (de) 1995-08-16
GR1000960B (el) 1993-03-16
CA2045483A1 (en) 1991-05-28
DE69021716T2 (de) 1996-02-22
BR9007082A (pt) 1991-12-24
AU6754990A (en) 1991-06-26
NO180382C (no) 1997-04-09
KR920701462A (ko) 1992-08-11
ZA909528B (en) 1991-10-30
FI102388B1 (fi) 1998-11-30
JP2577133B2 (ja) 1997-01-29
EP0455772A1 (de) 1991-11-13
HUT55837A (en) 1991-06-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee