ATE124869T1 - Stabilisierung von calcitonin enthaltenden pharmazeutischen verbindungen. - Google Patents

Stabilisierung von calcitonin enthaltenden pharmazeutischen verbindungen.

Info

Publication number
ATE124869T1
ATE124869T1 AT91311176T AT91311176T ATE124869T1 AT E124869 T1 ATE124869 T1 AT E124869T1 AT 91311176 T AT91311176 T AT 91311176T AT 91311176 T AT91311176 T AT 91311176T AT E124869 T1 ATE124869 T1 AT E124869T1
Authority
AT
Austria
Prior art keywords
stabilization
compounds containing
pharmaceutical compounds
acid
hct
Prior art date
Application number
AT91311176T
Other languages
English (en)
Inventor
Turdor Arvinte
Katherine Diana Ryman
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909026882A external-priority patent/GB9026882D0/en
Priority claimed from GB919119048A external-priority patent/GB9119048D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Application granted granted Critical
Publication of ATE124869T1 publication Critical patent/ATE124869T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
AT91311176T 1990-12-11 1991-12-02 Stabilisierung von calcitonin enthaltenden pharmazeutischen verbindungen. ATE124869T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909026882A GB9026882D0 (en) 1990-12-11 1990-12-11 Pharmaceutical compositions
GB919119048A GB9119048D0 (en) 1991-09-06 1991-09-06 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ATE124869T1 true ATE124869T1 (de) 1995-07-15

Family

ID=26298092

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91311176T ATE124869T1 (de) 1990-12-11 1991-12-02 Stabilisierung von calcitonin enthaltenden pharmazeutischen verbindungen.

Country Status (16)

Country Link
EP (1) EP0490549B1 (de)
JP (1) JP3179538B2 (de)
KR (1) KR100253862B1 (de)
AT (1) ATE124869T1 (de)
AU (1) AU653371B2 (de)
CA (1) CA2057291C (de)
DE (1) DE69111205T2 (de)
DK (1) DK0490549T3 (de)
ES (1) ES2074236T3 (de)
HU (1) HU213204B (de)
IE (1) IE66398B1 (de)
IL (1) IL100239A (de)
MX (1) MX9102446A (de)
NZ (1) NZ240901A (de)
PH (1) PH30776A (de)
PT (1) PT99727B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US5629020A (en) * 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5541155A (en) * 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5397479A (en) * 1993-04-26 1995-03-14 International Remote Imaging Systems, Inc. Composition and method for enrichment of white blood cells from whole human blood
EP0726075A1 (de) * 1995-02-08 1996-08-14 Therapicon Srl Nicht-inorganische pharmazeutische salzige Lösungen zur endonasale Verabreichung
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
EP0904065A4 (de) 1996-06-14 2000-06-14 Emisphere Tech Inc Mikroverkapselte duftstoffe und herstellungsverfahren
US5726154A (en) * 1996-06-28 1998-03-10 University Of Utah Research Foundation Stabilization and oral delivery of calcitonin
KR100611559B1 (ko) * 1998-05-08 2007-04-25 동아제약주식회사 칼시토닌을 함유한 비강투여용 약제학적 조성물
EP1232753B1 (de) * 1999-09-08 2008-03-19 Chugai Seiyaku Kabushiki Kaisha Stabile proteinlösung abgefüllt in einem behältnis aus hydrophobem harz und eine methode zur stabilisierung derselben
JP3498041B2 (ja) * 2000-05-29 2004-02-16 科研製薬株式会社 プラルモレリン含有点鼻用製剤
CA2610839C (en) 2005-06-14 2019-06-25 Amgen Inc. Self-buffering protein formulations
EP2471554A1 (de) * 2010-12-28 2012-07-04 Hexal AG Pharmazeutische Formulierung mit biopharmazeutischem Arzneimittel
SE536091C2 (sv) * 2011-04-14 2013-04-30 Pep Tonic Medical Ab Farmaceutisk komposition innehållande oxytocin eller fragment eller varianter därav och åtminstone en icke-jonisk cellulosaeter
KR102413592B1 (ko) 2016-10-21 2022-06-27 암젠 인크 약학적 제형 및 그의 제조 방법

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH657858A5 (de) * 1983-06-27 1986-09-30 Ciba Geigy Ag Substanz aus der gruppe der calcitonine.
JPS61194034A (ja) * 1985-02-25 1986-08-28 Teijin Ltd 経鼻投与用粉末状組成物
MY102411A (en) * 1986-12-23 1992-06-17 Ciba Geigy Ag Nasal solutions
US5059587A (en) * 1987-08-03 1991-10-22 Toyo Jozo Company, Ltd. Physiologically active peptide composition for nasal administration
US5236704A (en) * 1988-01-28 1993-08-17 Sumitomo Pharmaceuticals Co., Ltd. Controlled release formulation
US5026825A (en) * 1988-09-08 1991-06-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Intranasal calcitonin formulations
JPH02174726A (ja) * 1988-12-23 1990-07-06 Toyo Jozo Co Ltd エルカトニン水溶液組成物の安定化法
JP2514249B2 (ja) * 1989-05-23 1996-07-10 帝人株式会社 安定化されたカルシトニン類医薬組成物

Also Published As

Publication number Publication date
CA2057291C (en) 2003-09-09
CA2057291A1 (en) 1992-06-12
IE66398B1 (en) 1995-12-27
MX9102446A (es) 1992-07-01
IL100239A0 (en) 1992-09-06
NZ240901A (en) 1993-03-26
KR100253862B1 (ko) 2000-09-01
PT99727A (pt) 1992-10-30
JPH06340547A (ja) 1994-12-13
HU913887D0 (en) 1992-02-28
PT99727B (pt) 1999-05-31
AU653371B2 (en) 1994-09-29
HUT59832A (en) 1992-07-28
HU213204B (en) 1997-03-28
AU8889891A (en) 1992-06-18
KR920011516A (ko) 1992-07-24
IE914294A1 (en) 1992-06-17
EP0490549B1 (de) 1995-07-12
DK0490549T3 (da) 1995-08-21
JP3179538B2 (ja) 2001-06-25
PH30776A (en) 1997-10-17
DE69111205T2 (de) 1996-01-04
EP0490549A1 (de) 1992-06-17
IL100239A (en) 1996-06-18
DE69111205D1 (de) 1995-08-17
ES2074236T3 (es) 1995-09-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee