IT1247752B - Composizioni farmaceutiche aventi come principio attivo calcitonina da somministrarsi per via intranasale. - Google Patents
Composizioni farmaceutiche aventi come principio attivo calcitonina da somministrarsi per via intranasale.Info
- Publication number
- IT1247752B IT1247752B ITRM910038A ITRM910038A IT1247752B IT 1247752 B IT1247752 B IT 1247752B IT RM910038 A ITRM910038 A IT RM910038A IT RM910038 A ITRM910038 A IT RM910038A IT 1247752 B IT1247752 B IT 1247752B
- Authority
- IT
- Italy
- Prior art keywords
- active principle
- calcitonin
- administration
- pharmaceutical compositions
- intranasal route
- Prior art date
Links
- 102000055006 Calcitonin Human genes 0.000 title abstract 2
- 108060001064 Calcitonin Proteins 0.000 title abstract 2
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 title abstract 2
- 229960004015 calcitonin Drugs 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invenzione riguarda composizioni farmaceutiche adatte alla somministrazione per via intranasale contenenti come principio attivo una calcitonina, in soluzione acquosa salina. La stabilità chimica del principio attivo è prolungata nel tempo grazie alla presenza di un sistema tampone costituito da un amminoacido e da acido cloridrico.A tale composizioni secondo l'invenzione può inoltre essere aggiunto un sale quaternario amfifilico con funzione di agente conservante antimicrobico.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM910038A IT1247752B (it) | 1991-01-18 | 1991-01-18 | Composizioni farmaceutiche aventi come principio attivo calcitonina da somministrarsi per via intranasale. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITRM910038A IT1247752B (it) | 1991-01-18 | 1991-01-18 | Composizioni farmaceutiche aventi come principio attivo calcitonina da somministrarsi per via intranasale. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITRM910038A0 ITRM910038A0 (it) | 1991-01-18 |
| ITRM910038A1 ITRM910038A1 (it) | 1992-07-18 |
| IT1247752B true IT1247752B (it) | 1994-12-30 |
Family
ID=11399757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITRM910038A IT1247752B (it) | 1991-01-18 | 1991-01-18 | Composizioni farmaceutiche aventi come principio attivo calcitonina da somministrarsi per via intranasale. |
Country Status (1)
| Country | Link |
|---|---|
| IT (1) | IT1247752B (it) |
-
1991
- 1991-01-18 IT ITRM910038A patent/IT1247752B/it active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ITRM910038A0 (it) | 1991-01-18 |
| ITRM910038A1 (it) | 1992-07-18 |
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Legal Events
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|---|---|---|---|
| 0001 | Granted |