ES2074236T3 - Composiciones farmaceuticas que comprenden calcitonina. - Google Patents

Composiciones farmaceuticas que comprenden calcitonina.

Info

Publication number
ES2074236T3
ES2074236T3 ES91311176T ES91311176T ES2074236T3 ES 2074236 T3 ES2074236 T3 ES 2074236T3 ES 91311176 T ES91311176 T ES 91311176T ES 91311176 T ES91311176 T ES 91311176T ES 2074236 T3 ES2074236 T3 ES 2074236T3
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
compositions including
acid
hct
including calcitonin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91311176T
Other languages
English (en)
Inventor
Turdor Arvinte
Katherine Diana Ryman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909026882A external-priority patent/GB9026882D0/en
Priority claimed from GB919119048A external-priority patent/GB9119048D0/en
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2074236T3 publication Critical patent/ES2074236T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • External Artificial Organs (AREA)

Abstract

UNA SOLUCION ACUOSA ESTABLE DE CALCITONINA HUMANA (HCT) QUE PERMANECE LIBRE DE FIBRILLAS HCT POR AL MENOS 24 HORAS A 25 C, QUE COMPRENDE AGUA, HCT Y UN DERIVADO DE CELULOSA Y/O UN ACIDO; EL TIPO DE ACIDO Y LA CANTIDAD DE ACIDO ASI ESCOGIDO LOGRA DICHA ESTABILIDAD EN AUSENCIA DE UNA SAL O UN TOPE.
ES91311176T 1990-12-11 1991-12-02 Composiciones farmaceuticas que comprenden calcitonina. Expired - Lifetime ES2074236T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909026882A GB9026882D0 (en) 1990-12-11 1990-12-11 Pharmaceutical compositions
GB919119048A GB9119048D0 (en) 1991-09-06 1991-09-06 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ES2074236T3 true ES2074236T3 (es) 1995-09-01

Family

ID=26298092

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91311176T Expired - Lifetime ES2074236T3 (es) 1990-12-11 1991-12-02 Composiciones farmaceuticas que comprenden calcitonina.

Country Status (16)

Country Link
EP (1) EP0490549B1 (es)
JP (1) JP3179538B2 (es)
KR (1) KR100253862B1 (es)
AT (1) ATE124869T1 (es)
AU (1) AU653371B2 (es)
CA (1) CA2057291C (es)
DE (1) DE69111205T2 (es)
DK (1) DK0490549T3 (es)
ES (1) ES2074236T3 (es)
HU (1) HU213204B (es)
IE (1) IE66398B1 (es)
IL (1) IL100239A (es)
MX (1) MX9102446A (es)
NZ (1) NZ240901A (es)
PH (1) PH30776A (es)
PT (1) PT99727B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US5541155A (en) * 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5629020A (en) * 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5397479A (en) * 1993-04-26 1995-03-14 International Remote Imaging Systems, Inc. Composition and method for enrichment of white blood cells from whole human blood
DE726075T1 (de) * 1995-02-08 1996-12-12 Therapicon Srl Nicht-inorganische pharmazeutische salzige Lösungen zur endonasale Verabreichung
WO1997036480A1 (en) 1996-03-29 1997-10-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
AU3828597A (en) 1996-06-14 1998-01-07 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US5726154A (en) * 1996-06-28 1998-03-10 University Of Utah Research Foundation Stabilization and oral delivery of calcitonin
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6502208B1 (en) 1997-03-31 2002-12-31 International Business Machines Corporation Method and system for check stop error handling
KR100611559B1 (ko) * 1998-05-08 2007-04-25 동아제약주식회사 칼시토닌을 함유한 비강투여용 약제학적 조성물
ATE389414T1 (de) * 1999-09-08 2008-04-15 Chugai Pharmaceutical Co Ltd Stabile proteinlösung abgefüllt in einem behältnis aus hydrophobem harz und eine methode zur stabilisierung derselben
JP3498041B2 (ja) * 2000-05-29 2004-02-16 科研製薬株式会社 プラルモレリン含有点鼻用製剤
ES2776657T3 (es) 2005-06-14 2020-07-31 Amgen Inc Formulaciones de proteínas autotamponantes
EP2471554A1 (en) * 2010-12-28 2012-07-04 Hexal AG Pharmaceutical formulation comprising a biopharmaceutical drug
SE536091C2 (sv) * 2011-04-14 2013-04-30 Pep Tonic Medical Ab Farmaceutisk komposition innehållande oxytocin eller fragment eller varianter därav och åtminstone en icke-jonisk cellulosaeter
EP3528787B1 (en) 2016-10-21 2026-01-07 Amgen Inc. Pharmaceutical formulations and methods of making the same

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH657858A5 (de) * 1983-06-27 1986-09-30 Ciba Geigy Ag Substanz aus der gruppe der calcitonine.
JPS61194034A (ja) * 1985-02-25 1986-08-28 Teijin Ltd 経鼻投与用粉末状組成物
MY102411A (en) * 1986-12-23 1992-06-17 Ciba Geigy Ag Nasal solutions
US5059587A (en) * 1987-08-03 1991-10-22 Toyo Jozo Company, Ltd. Physiologically active peptide composition for nasal administration
ATE90570T1 (de) * 1988-01-29 1993-07-15 Sumitomo Pharma Verbesserte formulierungen mit kontrollierter abgabe.
US5026825A (en) * 1988-09-08 1991-06-25 Rhone-Poulenc Rorer Pharmaceuticals Inc. Intranasal calcitonin formulations
JPH02174726A (ja) * 1988-12-23 1990-07-06 Toyo Jozo Co Ltd エルカトニン水溶液組成物の安定化法
JP2514249B2 (ja) * 1989-05-23 1996-07-10 帝人株式会社 安定化されたカルシトニン類医薬組成物

Also Published As

Publication number Publication date
DE69111205D1 (de) 1995-08-17
HUT59832A (en) 1992-07-28
JPH06340547A (ja) 1994-12-13
IL100239A (en) 1996-06-18
KR920011516A (ko) 1992-07-24
CA2057291C (en) 2003-09-09
PT99727B (pt) 1999-05-31
PH30776A (en) 1997-10-17
KR100253862B1 (ko) 2000-09-01
PT99727A (pt) 1992-10-30
EP0490549A1 (en) 1992-06-17
CA2057291A1 (en) 1992-06-12
JP3179538B2 (ja) 2001-06-25
NZ240901A (en) 1993-03-26
ATE124869T1 (de) 1995-07-15
AU8889891A (en) 1992-06-18
HU213204B (en) 1997-03-28
MX9102446A (es) 1992-07-01
EP0490549B1 (en) 1995-07-12
AU653371B2 (en) 1994-09-29
DK0490549T3 (da) 1995-08-21
IE66398B1 (en) 1995-12-27
IL100239A0 (en) 1992-09-06
HU913887D0 (en) 1992-02-28
IE914294A1 (en) 1992-06-17
DE69111205T2 (de) 1996-01-04

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