ATE114160T1 - Immunogenische zusammensetzungen gegen gastrin- peptide. - Google Patents
Immunogenische zusammensetzungen gegen gastrin- peptide.Info
- Publication number
- ATE114160T1 ATE114160T1 AT90300456T AT90300456T ATE114160T1 AT E114160 T1 ATE114160 T1 AT E114160T1 AT 90300456 T AT90300456 T AT 90300456T AT 90300456 T AT90300456 T AT 90300456T AT E114160 T1 ATE114160 T1 AT E114160T1
- Authority
- AT
- Austria
- Prior art keywords
- immunogenic compositions
- disclosed
- compositions against
- compositions
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/595—Gastrins; Cholecystokinins [CCK]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/301,353 US5023077A (en) | 1989-01-24 | 1989-01-24 | Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease |
| US35119389A | 1989-05-12 | 1989-05-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE114160T1 true ATE114160T1 (de) | 1994-12-15 |
Family
ID=26972322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90300456T ATE114160T1 (de) | 1989-01-24 | 1990-01-17 | Immunogenische zusammensetzungen gegen gastrin- peptide. |
Country Status (12)
| Country | Link |
|---|---|
| US (3) | US5607676A (de) |
| EP (1) | EP0380230B1 (de) |
| JP (1) | JP2526418B2 (de) |
| AT (1) | ATE114160T1 (de) |
| AU (1) | AU645967B2 (de) |
| CA (1) | CA2045594C (de) |
| DE (1) | DE69014137T2 (de) |
| DK (1) | DK0380230T3 (de) |
| ES (1) | ES2063912T3 (de) |
| IE (1) | IE66267B1 (de) |
| PT (1) | PT92938B (de) |
| WO (1) | WO1990008774A1 (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6861510B1 (en) * | 1989-01-24 | 2005-03-01 | Aphton Corporation | Immunogenic compositions against gastrin peptides |
| US5023077A (en) * | 1989-01-24 | 1991-06-11 | Aphton Corporation | Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease |
| EP0380230B1 (de) * | 1989-01-24 | 1994-11-17 | Aphton Corporation | Immunogenische Zusammensetzungen gegen Gastrin-Peptide |
| US5468494A (en) * | 1993-11-12 | 1995-11-21 | Aphton Corp. | Immunogenic compositions against human gastrin 17 |
| US5688506A (en) * | 1994-01-27 | 1997-11-18 | Aphton Corp. | Immunogens against gonadotropin releasing hormone |
| GB9406974D0 (en) * | 1994-04-08 | 1994-06-01 | Pharmaceutical Proteins Ltd | Transgenic production |
| DE69740173D1 (de) * | 1996-02-08 | 2011-05-26 | Cancer Advances Inc | Immunologische methoden zur behandlung von gastrointestinalem krebs |
| US6072086A (en) * | 1996-04-12 | 2000-06-06 | Intergen Company | Method and composition for controlling formaldehyde fixation by delayed quenching |
| US6982249B1 (en) | 1997-04-23 | 2006-01-03 | The Regents Of The University Of Michigan | Bradykinin analogs as selective inhibitors of cell activation |
| WO1998047522A1 (en) * | 1997-04-23 | 1998-10-29 | The Regents Of The University Of Michigan | Bradykinin analogs as selective inhibitors of cell activation |
| US20040001842A1 (en) * | 1997-05-12 | 2004-01-01 | Dov Michaeli | Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors |
| DE69827621T9 (de) * | 1997-05-12 | 2007-06-06 | Aphton Corp., Woodland | Immunogene zusammensetzungen gegen den cck-b-gastrin-rezeptor und verfahren zur behandlung von tumoren |
| CA2332774A1 (en) * | 1998-05-15 | 1999-11-25 | Dov Michaeli | Method for the treatment of gastroesophageal reflux disease |
| EP1897556A1 (de) * | 1998-05-15 | 2008-03-12 | Receptor Biologix, Inc. | Vorbeugung und Behandlung von Hypergastrinämie |
| EP1579863A3 (de) * | 1998-05-15 | 2008-03-19 | Receptor Biologix, Inc. | Kombinationstherapie mit Anti-G17 Gastrin Antikörper zur Behandlung von Tumoren |
| PT1077721E (pt) * | 1998-05-15 | 2007-06-21 | Receptor Biologix Inc | Prevenção e tratamento da hipergastrinemia. |
| JP2002515457A (ja) * | 1998-05-15 | 2002-05-28 | アフトン コーポレーション | 腫瘍治療のための併用療法 |
| US20030068326A1 (en) * | 1998-05-15 | 2003-04-10 | Aphton Corporation | Method for the treatment of gastroesophageal reflux disease |
| JP2003522105A (ja) * | 1998-06-18 | 2003-07-22 | チョワース、ミッチャル、ワイ. | ヘリコバクター・ピロリ(Helicobacterpylori)関連疾患治療用医薬組成物 |
| CA2441228A1 (en) * | 2001-03-23 | 2002-10-03 | Aphton Corporation | Combination treatment of pancreatic cancer |
| US20090191232A1 (en) | 2001-05-04 | 2009-07-30 | Gevas Philip C | Combination therapy for the treatment of tumors |
| KR20040049830A (ko) * | 2001-07-09 | 2004-06-12 | 애프톤 코포레이션 | 간, 폐 및 식도의 암 및 전암 상태의 치료 및 예방 |
| EP1837031B1 (de) * | 2002-06-07 | 2009-10-14 | Waratah Pharmaceuticals, Inc. | Methoden und Kompositionen um Diabetes zu behandeln |
| US20050169979A1 (en) * | 2002-07-03 | 2005-08-04 | Dov Michaeli | Liposomal vaccine |
| JP2006506386A (ja) * | 2002-10-22 | 2006-02-23 | ワラタ ファーマシューティカルズ, インコーポレイテッド | 糖尿病の処置 |
| US20080096824A1 (en) * | 2003-02-28 | 2008-04-24 | Shigemi Matsuyama | Ku-70-derived bax-suppressing peptides and use thereof for the protection of damaged cells |
| CN1781023A (zh) | 2003-03-28 | 2006-05-31 | 埃弗顿有限公司 | 胃泌素激素免疫测定 |
| CN1997669A (zh) * | 2004-03-29 | 2007-07-11 | 受体生物技术公司 | 抗胃泌素激素单克隆抗体 |
| AU2005228897B2 (en) * | 2004-03-29 | 2009-12-10 | Cancer Advances, Inc. | Monoclonal antibodies to gastrin hormone |
| JP2008513536A (ja) | 2004-09-22 | 2008-05-01 | レセプター バイオロジックス インコーポレイテッド | プロガストリンに対するモノクローナル抗体 |
| GB201121571D0 (en) * | 2011-12-15 | 2012-01-25 | Astrimmune Ltd | Compounds and uses thereof |
| WO2014009209A2 (en) | 2012-07-13 | 2014-01-16 | S-Target Therapeutics Gmbh | Immunoregulatory vaccine |
| EP2999485B1 (de) | 2013-05-21 | 2018-01-31 | Tyg Oncology Ltd. | Immunogene gastrin-peptid-zusammensetzung |
| JP7469225B2 (ja) | 2017-06-15 | 2024-04-16 | キャンサー アドヴァンシーズ インク. | 腫瘍及び癌に対する体液性及び細胞性免疫を誘発するための組成物及び方法 |
| US12150978B2 (en) | 2017-06-15 | 2024-11-26 | Cancer Advances Inc. | Compositions and methods for preventing tumors and cancer |
| US20230398196A1 (en) * | 2020-11-06 | 2023-12-14 | Cancer Advances Inc. | Compositions and methods for enhancing t cell penetration of tumors and cancers |
| CN115639360B (zh) * | 2021-07-19 | 2025-05-13 | 武汉市朗典精医生物科技有限公司 | 制备前体胃泌素(pg80)抗体及建立clia检测pg80试剂盒 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3932242A (en) * | 1957-11-21 | 1976-01-13 | Bartley Charles E | Solid propellant with butyl rubber binder |
| DE2256445C3 (de) * | 1972-11-17 | 1981-11-05 | Hoechst Ag, 6000 Frankfurt | Heptapeptide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate |
| US4526716A (en) * | 1981-11-20 | 1985-07-02 | The Ohio State University | Antigenic modification of polypeptides |
| US4384995A (en) * | 1980-01-16 | 1983-05-24 | The Ohio State University | Antigenic modification of polypeptides |
| US4691006A (en) * | 1983-03-04 | 1987-09-01 | Ohio State University | Antigenic modification of polypeptides |
| SU1414392A1 (ru) * | 1982-12-29 | 1988-08-07 | Всесоюзный кардиологический научный центр АМН СССР | Противо звенное средство |
| FR2575164B1 (fr) * | 1984-12-20 | 1987-03-20 | Sanofi Sa | Esters de tri- et tetrapeptides inhibiteurs de la secretion gastrique, procede d'obtention et compositions pharmaceutiques les contenant |
| US5023077A (en) * | 1989-01-24 | 1991-06-11 | Aphton Corporation | Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease |
| EP0380230B1 (de) * | 1989-01-24 | 1994-11-17 | Aphton Corporation | Immunogenische Zusammensetzungen gegen Gastrin-Peptide |
| US5468494A (en) * | 1993-11-12 | 1995-11-21 | Aphton Corp. | Immunogenic compositions against human gastrin 17 |
-
1990
- 1990-01-17 EP EP90300456A patent/EP0380230B1/de not_active Expired - Lifetime
- 1990-01-17 DE DE69014137T patent/DE69014137T2/de not_active Expired - Fee Related
- 1990-01-17 ES ES90300456T patent/ES2063912T3/es not_active Expired - Lifetime
- 1990-01-17 DK DK90300456.2T patent/DK0380230T3/da active
- 1990-01-17 AT AT90300456T patent/ATE114160T1/de not_active IP Right Cessation
- 1990-01-23 IE IE25090A patent/IE66267B1/en not_active IP Right Cessation
- 1990-01-23 PT PT92938A patent/PT92938B/pt not_active IP Right Cessation
- 1990-01-23 JP JP2503438A patent/JP2526418B2/ja not_active Expired - Lifetime
- 1990-01-23 US US07/721,638 patent/US5607676A/en not_active Expired - Fee Related
- 1990-01-23 CA CA002045594A patent/CA2045594C/en not_active Expired - Fee Related
- 1990-01-23 AU AU50820/90A patent/AU645967B2/en not_active Ceased
- 1990-01-23 WO PCT/US1990/000520 patent/WO1990008774A1/en not_active Ceased
-
1994
- 1994-08-04 US US08/285,984 patent/US5609870A/en not_active Expired - Lifetime
-
1995
- 1995-06-05 US US08/462,158 patent/US5785970A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1990008774A1 (en) | 1990-08-09 |
| IE66267B1 (en) | 1995-12-27 |
| AU645967B2 (en) | 1994-02-03 |
| PT92938A (pt) | 1990-07-31 |
| PT92938B (pt) | 1996-09-30 |
| JPH04503072A (ja) | 1992-06-04 |
| US5785970A (en) | 1998-07-28 |
| DK0380230T3 (da) | 1995-01-16 |
| ES2063912T3 (es) | 1995-01-16 |
| US5609870A (en) | 1997-03-11 |
| IE900250L (en) | 1990-07-24 |
| CA2045594A1 (en) | 1990-07-25 |
| EP0380230B1 (de) | 1994-11-17 |
| JP2526418B2 (ja) | 1996-08-21 |
| EP0380230A3 (de) | 1991-06-26 |
| DE69014137D1 (de) | 1994-12-22 |
| DE69014137T2 (de) | 1995-06-08 |
| US5607676A (en) | 1997-03-04 |
| CA2045594C (en) | 2002-08-13 |
| AU5082090A (en) | 1990-08-24 |
| EP0380230A2 (de) | 1990-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |