ATE112849T1 - Verfahren und vorrichtung zum abgeben und auftragen von flüssigen reagenzien. - Google Patents

Verfahren und vorrichtung zum abgeben und auftragen von flüssigen reagenzien.

Info

Publication number
ATE112849T1
ATE112849T1 AT87116861T AT87116861T ATE112849T1 AT E112849 T1 ATE112849 T1 AT E112849T1 AT 87116861 T AT87116861 T AT 87116861T AT 87116861 T AT87116861 T AT 87116861T AT E112849 T1 ATE112849 T1 AT E112849T1
Authority
AT
Austria
Prior art keywords
transducer
dispensing
jetting tube
fluid
reagent
Prior art date
Application number
AT87116861T
Other languages
English (en)
Inventor
Donald J Hayes
David B Wallace
Donald J Verlee
Kenneth R Houseman
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25460832&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE112849(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE112849T1 publication Critical patent/ATE112849T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J4/00—Feed or outlet devices; Feed or outlet control devices
    • B01J4/02—Feed or outlet devices; Feed or outlet control devices for feeding measured, i.e. prescribed quantities of reagents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0268—Drop counters; Drop formers using pulse dispensing or spraying, eg. inkjet type, piezo actuated ejection of droplets from capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
    • G01F11/08—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the diaphragm or bellows type
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F11/00—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
    • G01F11/02—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
    • G01F11/08—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the diaphragm or bellows type
    • G01F11/088—Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement of the diaphragm or bellows type using a deformable conduit-like element
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00378—Piezoelectric or ink jet dispensers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1041—Ink-jet like dispensers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Nanotechnology (AREA)
  • Fluid Mechanics (AREA)
  • Materials Engineering (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Composite Materials (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Hydrology & Water Resources (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
AT87116861T 1986-11-17 1987-11-16 Verfahren und vorrichtung zum abgeben und auftragen von flüssigen reagenzien. ATE112849T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93147686A 1986-11-17 1986-11-17

Publications (1)

Publication Number Publication Date
ATE112849T1 true ATE112849T1 (de) 1994-10-15

Family

ID=25460832

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87116861T ATE112849T1 (de) 1986-11-17 1987-11-16 Verfahren und vorrichtung zum abgeben und auftragen von flüssigen reagenzien.

Country Status (7)

Country Link
EP (1) EP0268237B2 (de)
JP (1) JPH076975B2 (de)
KR (1) KR880006117A (de)
AT (1) ATE112849T1 (de)
AU (1) AU603617B2 (de)
CA (1) CA1308467C (de)
DE (1) DE3750655T3 (de)

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GB8810400D0 (en) 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
US7811751B2 (en) 1988-05-03 2010-10-12 Oxford Gene Technology Limited Analysing polynucleotide sequences
US5700637A (en) * 1988-05-03 1997-12-23 Isis Innovation Limited Apparatus and method for analyzing polynucleotide sequences and method of generating oligonucleotide arrays
US6054270A (en) * 1988-05-03 2000-04-25 Oxford Gene Technology Limited Analying polynucleotide sequences
US5275787A (en) * 1989-10-04 1994-01-04 Canon Kabushiki Kaisha Apparatus for separating or measuring particles to be examined in a sample fluid
DE69025370T2 (de) * 1989-10-04 1996-09-12 Canon Kk Gerät und Verfahren zur Trennung oder Messung von zu untersuchenden Teilchen in einer Flüssigkeitsprobe
DE4024545A1 (de) * 1990-08-02 1992-02-06 Boehringer Mannheim Gmbh Verfahren und vorrichtung zum dosierten zufuehren einer biochemischen analysefluessigkeit auf ein target
GB9115053D0 (en) * 1991-07-12 1991-08-28 Graseby Ionics Ltd Fluid sampling system
JPH058128U (ja) * 1991-07-15 1993-02-05 帝国ピストンリング株式会社 組合せオイルリング
DE69233087T2 (de) * 1991-11-22 2003-12-24 Affymetrix Inc N D Ges D Staat Verfahren zur Herstellung von Polymerarrays
DE4202850A1 (de) * 1992-01-31 1993-08-05 Boehringer Mannheim Gmbh Analysenelement fuer immunoassays
JPH0610900A (ja) * 1992-04-27 1994-01-21 Canon Inc 液体移動方法及び移動装置ならびにこれを利用した測定装置
US5947167A (en) * 1992-05-11 1999-09-07 Cytologix Corporation Dispensing assembly with interchangeable cartridge pumps
US6092695A (en) * 1992-05-11 2000-07-25 Cytologix Corporation Interchangeable liquid dispensing cartridge pump
US6180061B1 (en) 1992-05-11 2001-01-30 Cytologix Corporation Moving platform slide stainer with heating elements
US6537817B1 (en) 1993-05-31 2003-03-25 Packard Instrument Company Piezoelectric-drop-on-demand technology
US6203759B1 (en) 1996-05-31 2001-03-20 Packard Instrument Company Microvolume liquid handling system
US6521187B1 (en) 1996-05-31 2003-02-18 Packard Instrument Company Dispensing liquid drops onto porous brittle substrates
DE4331596A1 (de) * 1993-09-17 1995-03-23 Boehringer Mannheim Gmbh Verfahren zur quantitativen Analyse von Probenflüssigkeiten
US6428955B1 (en) 1995-03-17 2002-08-06 Sequenom, Inc. DNA diagnostics based on mass spectrometry
SE9502251D0 (sv) * 1995-06-21 1995-06-21 Pharmacia Ab Flow-through sampling cell and use thereof
JPH0990801A (ja) * 1995-09-20 1997-04-04 Ricoh Co Ltd 定着装置における駆動装置
US5958342A (en) * 1996-05-17 1999-09-28 Incyte Pharmaceuticals, Inc. Jet droplet device
EP0810438B1 (de) * 1996-05-31 2004-02-04 Packard Instrument Company, Inc. Vorrichtung zur Handhabung von Mikroflüssigkeitsmengen
US6083762A (en) * 1996-05-31 2000-07-04 Packard Instruments Company Microvolume liquid handling system
USRE38281E1 (en) 1996-07-26 2003-10-21 Biodot, Inc. Dispensing apparatus having improved dynamic range
US5916524A (en) 1997-07-23 1999-06-29 Bio-Dot, Inc. Dispensing apparatus having improved dynamic range
EP0912253B1 (de) * 1996-07-26 2003-04-02 Bio-Dot, Inc. Dosiervorrichtung mit erweitertem dynamikbereich
US6875620B1 (en) 1996-10-31 2005-04-05 Agilent Technologies, Inc. Tiling process for constructing a chemical array
EP1460083B1 (de) 1996-11-06 2006-01-18 Sequenom, Inc. Verfahren zur Analyse und Vorrichtung
US6024925A (en) 1997-01-23 2000-02-15 Sequenom, Inc. Systems and methods for preparing low volume analyte array elements
US5812272A (en) * 1997-01-30 1998-09-22 Hewlett-Packard Company Apparatus and method with tiled light source array for integrated assay sensing
DE19707204A1 (de) 1997-02-24 1998-08-27 Boehringer Mannheim Gmbh System zur Herstellung diagnostischer Vielfach-Testelemente
EP1512975A3 (de) * 1997-04-08 2006-05-24 Packard Instrument Company, Inc. Vorrichtung zur Handhabung von Mikroflüssigkeitsmengen
AU6963798A (en) * 1997-04-08 1998-10-30 Packard Instrument Company Inc. Microvolume liquid handling system
US6268131B1 (en) 1997-12-15 2001-07-31 Sequenom, Inc. Mass spectrometric methods for sequencing nucleic acids
US6537505B1 (en) 1998-02-20 2003-03-25 Bio Dot, Inc. Reagent dispensing valve
US6183693B1 (en) 1998-02-27 2001-02-06 Cytologix Corporation Random access slide stainer with independent slide heating regulation
JP3801380B2 (ja) * 1998-04-29 2006-07-26 ヒューレット・パッカード・カンパニー 多室流体供給源
US6309062B1 (en) 1998-10-29 2001-10-30 Hewlett-Packard Company Multi-chamber fluid supply
US6126268A (en) * 1998-04-29 2000-10-03 Hewlett-Packard Company Multi-chamber ink supply
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US7541152B2 (en) 2002-12-24 2009-06-02 Agilent Technologies, Inc. Integrated light source for diagnostic arrays
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Also Published As

Publication number Publication date
EP0268237A3 (en) 1988-11-30
EP0268237A2 (de) 1988-05-25
AU8120787A (en) 1988-05-19
DE3750655T3 (de) 2003-04-24
KR880006117A (ko) 1988-07-21
DE3750655T2 (de) 1995-05-11
JPH076975B2 (ja) 1995-01-30
EP0268237B1 (de) 1994-10-12
CA1308467C (en) 1992-10-06
DE3750655D1 (de) 1994-11-17
JPS63139253A (ja) 1988-06-11
AU603617B2 (en) 1990-11-22
EP0268237B2 (de) 2002-12-18

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