ATE107313T1 - Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika. - Google Patents

Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika.

Info

Publication number
ATE107313T1
ATE107313T1 AT90906800T AT90906800T ATE107313T1 AT E107313 T1 ATE107313 T1 AT E107313T1 AT 90906800 T AT90906800 T AT 90906800T AT 90906800 T AT90906800 T AT 90906800T AT E107313 T1 ATE107313 T1 AT E107313T1
Authority
AT
Austria
Prior art keywords
amino acid
aeruginosa
diagnostics
pseudomonas aeruginosa
immunogens
Prior art date
Application number
AT90906800T
Other languages
English (en)
Inventor
Robert S Hodges
William Paranchych
Kok K Lee
Sastry A Parami
Randall T Irvin
Peter C Doig
Original Assignee
Univ Alberta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Alberta filed Critical Univ Alberta
Application granted granted Critical
Publication of ATE107313T1 publication Critical patent/ATE107313T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • C07K16/461Igs containing Ig-regions, -domains or -residues form different species
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT90906800T 1989-04-28 1990-04-26 Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika. ATE107313T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34456589A 1989-04-28 1989-04-28

Publications (1)

Publication Number Publication Date
ATE107313T1 true ATE107313T1 (de) 1994-07-15

Family

ID=23351056

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90906800T ATE107313T1 (de) 1989-04-28 1990-04-26 Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika.

Country Status (9)

Country Link
US (2) US5445818A (de)
EP (1) EP0469045B1 (de)
JP (1) JP2963536B2 (de)
AT (1) ATE107313T1 (de)
AU (1) AU5533490A (de)
CA (3) CA1340530C (de)
DE (1) DE69010001T2 (de)
DK (1) DK0469045T3 (de)
WO (1) WO1990013563A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494672A (en) * 1989-04-28 1996-02-27 S.P.I. Synthetic Peptides Incorporated Pseudomonas peptide composition and method
US5223604A (en) * 1991-06-25 1993-06-29 S.P.I. Synthetic Peptides Incorporated Pseudomonas exoenzyme s peptide composition and method
US6613530B1 (en) 1994-07-25 2003-09-02 Roche Diagnostics Gmbh Determination of a specific immunoglobulin using multiple antigens
US6872398B2 (en) * 1995-12-22 2005-03-29 The United States Of America As Represented By The Secretary Of The Army Conjugate vaccine against gram-negative bacterial infections
US6270777B1 (en) * 1996-12-20 2001-08-07 University Technologies International Inc. Conserved metalloprotease epitopes
US20030054012A1 (en) * 2000-05-12 2003-03-20 Fitzgerald David J. Pseudomonas exotoxin a-like chimeric immunogens for eliciting a secretory iga-mediated immune response
DK1000163T3 (da) * 1997-07-11 2006-02-06 Us Gov Health & Human Serv Pseudomonas-exotoksin A-lignende kimære immunogener
US7314632B1 (en) * 1997-07-11 2008-01-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pseudomonas exotoxin A-like chimeric immunogens
CA2329689A1 (en) * 1998-06-12 1999-12-23 The Governors Of The University Of Alberta Composition and method for treatment of pseudomonas
US20030228324A1 (en) * 1999-05-06 2003-12-11 Malcolm Andrew J. Peptide compositions and methods of producing and using same
US6863896B1 (en) * 1999-10-26 2005-03-08 Chiron Corporation Plant lectins as mucosal adjuvants
ES2322240T3 (es) * 2000-12-21 2009-06-18 The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services Una proteina quimerica que comprende secuencias de exotoxina a de pseudomonas no toxica y de pilina de tipo iv.
US7132101B2 (en) 2002-02-27 2006-11-07 Duquesne University Of The Holy Ghost Compositions and methods for eliciting an immune response to gram-negative bacterial infections
WO2006041906A2 (en) 2004-10-04 2006-04-20 Trinity Biosystems, Inc. Methods and compositions for immunizing against pseudomonas infection
WO2007089272A2 (en) 2005-07-22 2007-08-09 The Regents Of The University Of Colorado, A Body Corporate Non-toxic biofilm inhibitor
WO2011094363A2 (en) 2010-01-26 2011-08-04 The Regents Of The University Of Colorado Influenza virus compositions and methods for universal vaccines
CN107002119A (zh) 2014-03-24 2017-08-01 豪夫迈·罗氏有限公司 使用c‑met拮抗剂的癌症治疗及前者与hgf表达的关联
KR20200018483A (ko) 2017-06-14 2020-02-19 비로메틱스 아게 호흡기 합포체 바이러스에 대한 방어를 위한 고리형 펩티드
AU2019408048A1 (en) 2018-12-20 2021-06-24 Universität Zürich Lipopeptide building blocks and synthetic virus-like particles
US20230355737A1 (en) 2020-09-28 2023-11-09 Dbv Technologies Particle comprising an rsv-f protein for use in rsv vaccination

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0048422A3 (de) * 1980-09-15 1983-08-24 Bactex Incorporated Haare von Pseudomonas-Aeruginosa und deren Verwendung als Impfstoffe gegen infektiöse P.Aeruginosa
US4443549A (en) * 1981-10-19 1984-04-17 Molecular Genetics, Inc. Production of monoclonal antibodies against bacterial adhesins
US4886663A (en) * 1983-01-03 1989-12-12 Scripps Clinic And Research Foundation Synthetic heat-stable enterotoxin polypeptide of Escherichia coli and multimers thereof
DE3465051D1 (en) * 1983-07-23 1987-09-03 Zahnradfabrik Friedrichshafen Pressure medium control unit for servo steerings
DK219084D0 (da) * 1984-05-02 1984-05-02 Frederik Carl Peter Lindberg Antigen
CA1256370A (en) * 1984-02-24 1989-06-27 Yuzuru Homma Toxoids of elastase of pseudomonas aeruginosa origin
US4702911A (en) * 1985-09-27 1987-10-27 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
CA1319101C (en) * 1986-09-03 1993-06-15 Marta Iris Sabara Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules
JP2635742B2 (ja) * 1986-12-22 1997-07-30 トリオン、フォルスクニング‐オホ、ウトベクリングス、アクチェボラーグ 新規ポリペプチド及びその用途
US5494672A (en) * 1989-04-28 1996-02-27 S.P.I. Synthetic Peptides Incorporated Pseudomonas peptide composition and method

Also Published As

Publication number Publication date
EP0469045A1 (de) 1992-02-05
WO1990013563A1 (en) 1990-11-15
US5445818A (en) 1995-08-29
JP2963536B2 (ja) 1999-10-18
DE69010001D1 (de) 1994-07-21
US5612036A (en) 1997-03-18
DK0469045T3 (da) 1994-09-26
AU5533490A (en) 1990-11-29
CA2443232A1 (en) 1990-10-29
CA2053924A1 (en) 1990-10-29
DE69010001T2 (de) 1994-09-22
CA1340530C (en) 1999-05-04
EP0469045B1 (de) 1994-06-15
JPH04504719A (ja) 1992-08-20
CA2053924C (en) 2003-10-21

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee