DE69010001D1 - Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika. - Google Patents

Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika.

Info

Publication number
DE69010001D1
DE69010001D1 DE69010001T DE69010001T DE69010001D1 DE 69010001 D1 DE69010001 D1 DE 69010001D1 DE 69010001 T DE69010001 T DE 69010001T DE 69010001 T DE69010001 T DE 69010001T DE 69010001 D1 DE69010001 D1 DE 69010001D1
Authority
DE
Germany
Prior art keywords
amino acid
aeruginosa
piline
diagnostics
peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69010001T
Other languages
English (en)
Other versions
DE69010001T2 (de
Inventor
Robert Hodges
William Paranchych
Kok Lee
Sastry Parami
Randall Irvin
Peter Doig
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Alberta
Original Assignee
University of Alberta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Alberta filed Critical University of Alberta
Publication of DE69010001D1 publication Critical patent/DE69010001D1/de
Application granted granted Critical
Publication of DE69010001T2 publication Critical patent/DE69010001T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69010001T 1989-04-28 1990-04-26 Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika. Expired - Fee Related DE69010001T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34456589A 1989-04-28 1989-04-28
PCT/CA1990/000135 WO1990013563A1 (en) 1989-04-28 1990-04-26 Synthetic pseudomonas aeruginosa pilin peptide and related vaccines and diagnostics

Publications (2)

Publication Number Publication Date
DE69010001D1 true DE69010001D1 (de) 1994-07-21
DE69010001T2 DE69010001T2 (de) 1994-09-22

Family

ID=23351056

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69010001T Expired - Fee Related DE69010001T2 (de) 1989-04-28 1990-04-26 Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika.

Country Status (9)

Country Link
US (2) US5445818A (de)
EP (1) EP0469045B1 (de)
JP (1) JP2963536B2 (de)
AT (1) ATE107313T1 (de)
AU (1) AU5533490A (de)
CA (3) CA1340530C (de)
DE (1) DE69010001T2 (de)
DK (1) DK0469045T3 (de)
WO (1) WO1990013563A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5494672A (en) * 1989-04-28 1996-02-27 S.P.I. Synthetic Peptides Incorporated Pseudomonas peptide composition and method
US5223604A (en) * 1991-06-25 1993-06-29 S.P.I. Synthetic Peptides Incorporated Pseudomonas exoenzyme s peptide composition and method
WO1996003652A1 (de) 1994-07-25 1996-02-08 Boehringer Mannheim Gmbh Bestimmung von spezifischem immunglobulin unter verwendung multipler antigene
US6872398B2 (en) * 1995-12-22 2005-03-29 The United States Of America As Represented By The Secretary Of The Army Conjugate vaccine against gram-negative bacterial infections
US6270777B1 (en) * 1996-12-20 2001-08-07 University Technologies International Inc. Conserved metalloprotease epitopes
US7314632B1 (en) * 1997-07-11 2008-01-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Pseudomonas exotoxin A-like chimeric immunogens
ES2249838T3 (es) * 1997-07-11 2006-04-01 The Government Of The Usa As Represented By The Secretary Of The Depar. Of Health And Human Services Inmunogenos quimericos similares a la exotoxina a de pseudomonas.
US20030054012A1 (en) * 2000-05-12 2003-03-20 Fitzgerald David J. Pseudomonas exotoxin a-like chimeric immunogens for eliciting a secretory iga-mediated immune response
DE69906729T2 (de) * 1998-06-12 2004-02-05 The Governors Of The University Of Alberta, Edmonton Zusammensetzung und methode zur behandlung von pseudomonas aeruginosa infektionen
US20030228324A1 (en) * 1999-05-06 2003-12-11 Malcolm Andrew J. Peptide compositions and methods of producing and using same
US6863896B1 (en) * 1999-10-26 2005-03-08 Chiron Corporation Plant lectins as mucosal adjuvants
EP1379550B1 (de) * 2000-12-21 2009-03-11 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Ein chimäres protein das nichttoxische pseudomonas exotoxin a und typ iv pilin sequenzen enthält
US7132101B2 (en) * 2002-02-27 2006-11-07 Duquesne University Of The Holy Ghost Compositions and methods for eliciting an immune response to gram-negative bacterial infections
AU2005294436A1 (en) 2004-10-04 2006-04-20 Trinity Biosystems, Inc. Methods and compositions for immunizing against Pseudomonas infection
EP1919494A4 (de) 2005-07-22 2011-11-09 Univ Colorado Regents Nichttoxischer biofolien-hemmer
CA2825952A1 (en) 2010-01-26 2011-08-04 Robert S. Hodges Influenza virus compositions and methods for universal vaccines
MX2016012285A (es) 2014-03-24 2017-01-23 Genentech Inc Tratamiento de cáncer con antagonista de c-met y correlación de estos con la expresión de hgf.
EP3638284B1 (de) 2017-06-14 2023-08-30 Virometix AG Cyclische peptide zum schütz gegen den respiratorischen synzytialvirus
JP2022514411A (ja) 2018-12-20 2022-02-10 ヴァイロメティックス アーゲー リポペプチドビルディングブロックおよび合成ウイルス様粒子
US20230355737A1 (en) 2020-09-28 2023-11-09 Dbv Technologies Particle comprising an rsv-f protein for use in rsv vaccination

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0048422A3 (de) * 1980-09-15 1983-08-24 Bactex Incorporated Haare von Pseudomonas-Aeruginosa und deren Verwendung als Impfstoffe gegen infektiöse P.Aeruginosa
US4443549A (en) * 1981-10-19 1984-04-17 Molecular Genetics, Inc. Production of monoclonal antibodies against bacterial adhesins
US4886663A (en) * 1983-01-03 1989-12-12 Scripps Clinic And Research Foundation Synthetic heat-stable enterotoxin polypeptide of Escherichia coli and multimers thereof
BR8407326A (pt) * 1983-07-23 1986-09-23 Zahnradfabrik Friedrichshafen Dispositivo de comando de medium de pressao para direcoes de forca auxiliar
DK219084D0 (da) * 1984-05-02 1984-05-02 Frederik Carl Peter Lindberg Antigen
CA1256370A (en) * 1984-02-24 1989-06-27 Yuzuru Homma Toxoids of elastase of pseudomonas aeruginosa origin
US4702911A (en) * 1985-09-27 1987-10-27 Immunomed Corporation Preparation of bacterium pili subunits and vaccines containing pili subunits
CA1319101C (en) * 1986-09-03 1993-06-15 Marta Iris Sabara Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules
EP0279151B1 (de) * 1986-12-22 1993-04-28 Trion Forskning- Och Utvecklings Aktiebolag Pertussis-Toxin-Polypeptid und seine Applikationen
US5494672A (en) * 1989-04-28 1996-02-27 S.P.I. Synthetic Peptides Incorporated Pseudomonas peptide composition and method

Also Published As

Publication number Publication date
CA2053924A1 (en) 1990-10-29
AU5533490A (en) 1990-11-29
JPH04504719A (ja) 1992-08-20
US5612036A (en) 1997-03-18
EP0469045A1 (de) 1992-02-05
CA1340530C (en) 1999-05-04
ATE107313T1 (de) 1994-07-15
CA2053924C (en) 2003-10-21
US5445818A (en) 1995-08-29
DK0469045T3 (da) 1994-09-26
WO1990013563A1 (en) 1990-11-15
CA2443232A1 (en) 1990-10-29
DE69010001T2 (de) 1994-09-22
JP2963536B2 (ja) 1999-10-18
EP0469045B1 (de) 1994-06-15

Similar Documents

Publication Publication Date Title
DE69010001T2 (de) Synthetisches pseudomonas aeruginosa pilin-peptid und verwandte impfstoffe und diagnostika.
ES2540771T3 (es) Composición de anticuerpos para uso en vacunación contra estafilococos
KR950702839A (ko) 레트로, 인버소-, 및 레트로- 인버소 합성 펩티드 유사체(retro-, inverso-, and retro-inverso synthetic peptide analogues)
RU98118184A (ru) Пептидные иммуногены для вакцинации и лечения аллергии
DE69327587D1 (de) Konjugate von schwach immunogenen antigenen und synthetischen peptidträgern und impfstoffe diese enthaltend
NO913518L (no) Vaksiner for ikke typebestembar haemophilus influenzae.
SE7604972L (sv) Antigeniskt aktiv polypeptid och forfarande for dess framstellning
DE69738770D1 (de) Porphyromonas gingivalis Antigene zur Diagnose und Behandlung von Periodontitis
Hudecz Manipulation of epitope function by modification of peptide structure: a minireview
DE59101577D1 (de) Immunologisch aktive peptide bzw. polypeptide des parvovirus b19.
KR920004422A (ko) Hiv의 주요 중화 결정인자
CA2128407A1 (en) Synthetic peptides for a rubella vaccine
PT87239A (pt) Process for the preparation of peptides
DK0426314T3 (da) HIV-relaterede peptider
FR2408581A1 (fr) Composition de pentapeptide, son procede d'obtention et composition therapeutique en comportant
Lüscher et al. Induction of immunological tolerance to the penicilloyl antigenic determinant—iv. The effect of BPO-oligolysines and cholestanol-bearing BPO-oligolysines on murine IgE responses
GB2314560A (en) Synthetic peptides of m. gallisepticum, antibodies thereto, their preparations and use
FI961398A (fi) Menetelmä terapeuttisesti käyttökelpoisen peptidin valmistamiseksi
ES2065254A1 (es) Peptidos y vacunas sinteticas contra parvovirus canino y otros virus relacionados.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee