ATE100210T1 - Lyophilisiertes mdm enthaltende zusammensetzung und verfahren zu deren herstellung. - Google Patents
Lyophilisiertes mdm enthaltende zusammensetzung und verfahren zu deren herstellung.Info
- Publication number
- ATE100210T1 ATE100210T1 AT89119819T AT89119819T ATE100210T1 AT E100210 T1 ATE100210 T1 AT E100210T1 AT 89119819 T AT89119819 T AT 89119819T AT 89119819 T AT89119819 T AT 89119819T AT E100210 T1 ATE100210 T1 AT E100210T1
- Authority
- AT
- Austria
- Prior art keywords
- solution
- acid
- benzylpenicilloic
- benzylpenilloic
- benzylpenicillin
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000243 solution Substances 0.000 abstract 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 abstract 6
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 4
- HCYWNSXLUZRKJX-RWMBFGLXSA-N benzylpenicilloic acid Chemical compound N1[C@@H](C(O)=O)C(C)(C)S[C@@H]1[C@@H](C(O)=O)NC(=O)CC1=CC=CC=C1 HCYWNSXLUZRKJX-RWMBFGLXSA-N 0.000 abstract 4
- LRWFMQCGNBOTQP-OLZOCXBDSA-N benzylpenilloic acid Chemical compound N1[C@@H](C(O)=O)C(C)(C)S[C@@H]1CNC(=O)CC1=CC=CC=C1 LRWFMQCGNBOTQP-OLZOCXBDSA-N 0.000 abstract 3
- 206010020751 Hypersensitivity Diseases 0.000 abstract 2
- 229910052783 alkali metal Inorganic materials 0.000 abstract 2
- -1 alkali metal salt Chemical class 0.000 abstract 2
- 208000026935 allergic disease Diseases 0.000 abstract 2
- 239000006179 pH buffering agent Substances 0.000 abstract 2
- 235000019371 penicillin G benzathine Nutrition 0.000 abstract 2
- 229940056360 penicillin g Drugs 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 229930182555 Penicillin Natural products 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000008014 freezing Effects 0.000 abstract 1
- 238000007710 freezing Methods 0.000 abstract 1
- 230000009610 hypersensitivity Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9446—Antibacterials
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26574988A | 1988-11-01 | 1988-11-01 | |
| EP89119819A EP0367090B1 (de) | 1988-11-01 | 1989-10-25 | Lyophilisiertes MDM enthaltende Zusammensetzung und Verfahren zu deren Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE100210T1 true ATE100210T1 (de) | 1994-01-15 |
Family
ID=23011751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89119819T ATE100210T1 (de) | 1988-11-01 | 1989-10-25 | Lyophilisiertes mdm enthaltende zusammensetzung und verfahren zu deren herstellung. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0367090B1 (de) |
| AT (1) | ATE100210T1 (de) |
| DE (1) | DE68912270T2 (de) |
| DK (1) | DK542089A (de) |
| ES (1) | ES2048263T3 (de) |
| IE (1) | IE60788B1 (de) |
| PT (1) | PT92163B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT1588U1 (de) * | 1994-04-27 | 1997-08-25 | Mahl Christian Dr | Verfahren zur herstellung von testsubstanzen für verfahren mit erfassung elektromagnetischer schwingungen |
| US7932365B2 (en) * | 2003-11-08 | 2011-04-26 | Pro Thera Biologics, Llc | Preparation and composition of inter-alpha inhibitor proteins from human plasma for therapeutic use |
| PT2291654T (pt) | 2008-05-28 | 2018-06-15 | Prothera Biologics Inc | Preparação e composição de proteínas inibidoras de interalfa do sangue |
| US9572872B2 (en) | 2012-09-09 | 2017-02-21 | Prothera Biologics, Inc. | Treatment of disease using inter-alpha inhibitor proteins |
| US9409662B2 (en) | 2013-01-15 | 2016-08-09 | Teva Pharmaceutical Industries, Ltd. | Formulations of albu-BChE, preparation and uses thereof |
| EP2945593A4 (de) * | 2013-01-15 | 2016-08-31 | Teva Pharma | Verfahren zur lyophilisierung |
| CN106187934A (zh) * | 2016-07-08 | 2016-12-07 | 上海上药新亚药业有限公司 | 一种羧苄西林钠杂质g的合成方法 |
| CA3036553A1 (en) | 2016-09-13 | 2018-03-22 | Prothera Biologics, Inc. | Methods for treating pulmonary disease using inter-alpha inhibitor proteins |
| KR102587810B1 (ko) | 2017-04-25 | 2023-10-11 | 프로테라 바이오로직스, 인크. | 인터-알파 억제제 단백질을 정량화하는 방법 |
| US20180326095A1 (en) * | 2017-05-11 | 2018-11-15 | AllerQuest LLC | Kits and methods to detect penicillin allergy |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4316882A (en) * | 1978-04-20 | 1982-02-23 | Levine Bernard B | Compositions for testing to predict and/or diagnose allergy to penicillins |
| US4183910A (en) * | 1978-04-20 | 1980-01-15 | Levine Bernard B | Method for testing to predict and/or diagnose allergy to penicillins, and compounds and compositions for use in such tests |
| JPS63174927A (ja) * | 1987-01-14 | 1988-07-19 | Tanabe Seiyaku Co Ltd | 抗菌性凍結乾燥製剤 |
-
1989
- 1989-10-25 ES ES89119819T patent/ES2048263T3/es not_active Expired - Lifetime
- 1989-10-25 DE DE89119819T patent/DE68912270T2/de not_active Expired - Lifetime
- 1989-10-25 EP EP89119819A patent/EP0367090B1/de not_active Expired - Lifetime
- 1989-10-25 AT AT89119819T patent/ATE100210T1/de not_active IP Right Cessation
- 1989-10-30 IE IE339789A patent/IE60788B1/en not_active IP Right Cessation
- 1989-10-31 PT PT92163A patent/PT92163B/pt not_active IP Right Cessation
- 1989-10-31 DK DK542089A patent/DK542089A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IE893397L (en) | 1990-05-01 |
| DE68912270T2 (de) | 1994-04-28 |
| DE68912270D1 (de) | 1994-02-24 |
| DK542089D0 (da) | 1989-10-31 |
| EP0367090A1 (de) | 1990-05-09 |
| IE60788B1 (en) | 1994-08-10 |
| ES2048263T3 (es) | 1994-03-16 |
| PT92163A (pt) | 1990-05-31 |
| DK542089A (da) | 1990-05-02 |
| EP0367090B1 (de) | 1994-01-12 |
| PT92163B (pt) | 1995-07-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |