AT8372U2 - Desmopressin umfassende zusammensetzung - Google Patents
Desmopressin umfassende zusammensetzung Download PDFInfo
- Publication number
- AT8372U2 AT8372U2 AT0020406U AT2042006U AT8372U2 AT 8372 U2 AT8372 U2 AT 8372U2 AT 0020406 U AT0020406 U AT 0020406U AT 2042006 U AT2042006 U AT 2042006U AT 8372 U2 AT8372 U2 AT 8372U2
- Authority
- AT
- Austria
- Prior art keywords
- desmopressin
- comprehensive composition
- active ingredient
- dosage form
- comprehensive
- Prior art date
Links
- 108010000437 Deamino Arginine Vasopressin Proteins 0.000 title abstract 2
- NFLWUMRGJYTJIN-NXBWRCJVSA-N desmopressin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSCCC(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(N)=O)=O)CCC(=O)N)C1=CC=CC=C1 NFLWUMRGJYTJIN-NXBWRCJVSA-N 0.000 title abstract 2
- 229960004281 desmopressin Drugs 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000002552 dosage form Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000007909 solid dosage form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Die vorliegende Erfindung betrifft eine neue pharmazeutische Zusammensetzung als feste Arzneiform, die Desmopressin als therapeutisch wirksamen Bestandteil umfaßt. Sie behandelt Mittel zur Bereitstellung einer erhöhten Haltbarkeit des wirksamen Bestandteils in der Arzneiform.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0024906U AT8429U3 (de) | 2006-03-02 | 2006-03-31 | Herstellung einer desmopressin umfassenden zusammensetzung |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0600482A SE528446C2 (sv) | 2006-03-02 | 2006-03-02 | Farmaceutisk sammansättning innefattande desmopressin, kiseldioxid och stärkelse |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AT8372U2 true AT8372U2 (de) | 2006-07-15 |
| AT8372U3 AT8372U3 (de) | 2007-03-15 |
Family
ID=36218059
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06005326T ATE394095T1 (de) | 2006-03-02 | 2006-03-15 | Stabile desmopressinformulierung in fester form |
| AT0020406U AT8372U3 (de) | 2006-03-02 | 2006-03-16 | Desmopressin umfassende zusammensetzung |
| AT0043906A AT503320A1 (de) | 2006-03-02 | 2006-03-16 | Desmopressin umfassende zusammensetzung |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06005326T ATE394095T1 (de) | 2006-03-02 | 2006-03-15 | Stabile desmopressinformulierung in fester form |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT0043906A AT503320A1 (de) | 2006-03-02 | 2006-03-16 | Desmopressin umfassende zusammensetzung |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20100273709A1 (de) |
| EP (1) | EP1829532B1 (de) |
| JP (1) | JP4976428B2 (de) |
| AT (3) | ATE394095T1 (de) |
| CY (1) | CY1108231T1 (de) |
| DE (2) | DE602006001103D1 (de) |
| DK (1) | DK1829532T3 (de) |
| ES (1) | ES2304033T3 (de) |
| IL (1) | IL193250A0 (de) |
| NL (1) | NL1031397C2 (de) |
| NO (1) | NO20083555L (de) |
| PL (1) | PL1829532T3 (de) |
| PT (1) | PT1829532E (de) |
| RU (1) | RU2340351C1 (de) |
| SE (1) | SE528446C2 (de) |
| SI (1) | SI1829532T1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0210397D0 (en) | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| PT1530967E (pt) * | 2003-11-13 | 2006-09-29 | Ferring Bv | Embalagem blister e uma forma de dosagem solida que compreende desmopressina. |
| CN103304639A (zh) * | 2013-06-08 | 2013-09-18 | 深圳翰宇药业股份有限公司 | 一种纯化去氨加压素中间体的方法 |
| US9375478B1 (en) | 2015-01-30 | 2016-06-28 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4285858A (en) * | 1979-10-30 | 1981-08-25 | Mt. Sinai School Of Medicine Of The City University Of N.Y. | Vasopressin analogs |
| US4263283A (en) * | 1980-05-16 | 1981-04-21 | Ferring Pharmaceuticals, Inc. | Method for prophylaxis and/or treatment of sickle cell disease |
| SE8306367L (sv) * | 1983-11-18 | 1985-05-19 | Ferring Ab | Antidiuretiskt verkande farmaceutiskt preparat |
| US4863737A (en) * | 1985-05-01 | 1989-09-05 | University Of Utah | Compositions and methods of manufacture of compressed powder medicaments |
| US4764378A (en) * | 1986-02-10 | 1988-08-16 | Zetachron, Inc. | Buccal drug dosage form |
| US6746678B1 (en) * | 1991-02-22 | 2004-06-08 | Howard K. Shapiro | Method of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with medicaments |
| US7074871B2 (en) * | 1992-05-29 | 2006-07-11 | Basell Poliolefine Italia S.R.L. | Crystalline polymers of propylene having improved processability in the molten state and process for their preparation |
| SE9300937L (sv) * | 1993-03-19 | 1994-09-20 | Anne Fjellestad Paulsen | Komposition för oral administrering av peptider |
| SE501677C2 (sv) * | 1993-06-18 | 1995-04-10 | Ferring Bv | Biologiskt aktiva vasopressinanaloger, farmaceutiska preparat innehållande dem samt deras användning för framställning av läkemedel |
| HU221617B1 (hu) * | 1993-06-29 | 2002-12-28 | Ferring B.V. | Vizes készítmény dezmopresszin nazális adagolására |
| US5985835A (en) * | 1993-12-23 | 1999-11-16 | Ferring B.V. | Desmopressin for nocturia, incontinence and enuresis |
| ES2149880T3 (es) * | 1993-06-29 | 2000-11-16 | Ferring Bv | Sintesis de peptidos ciclicos. |
| US5482931A (en) * | 1993-06-29 | 1996-01-09 | Ferring Ab | Stabilized pharmaceutical peptide compositions |
| US5500413A (en) * | 1993-06-29 | 1996-03-19 | Ferring Ab | Process for manufacture of 1-deamino-8-D-arginine vasopressin |
| US5674850A (en) * | 1993-12-23 | 1997-10-07 | Ferring Ab | High purity desmopressin produced in large single batches |
| SE9400918L (sv) * | 1994-03-18 | 1995-09-19 | Anne Fjellstad Paulsen | Stabiliserad komposition för oral administrering av peptider |
| US5849322A (en) * | 1995-10-23 | 1998-12-15 | Theratech, Inc. | Compositions and methods for buccal delivery of pharmaceutical agents |
| US5763398A (en) * | 1996-06-20 | 1998-06-09 | Ferring B.V. | Nasal administration of desmopressin |
| US5922680A (en) * | 1996-10-23 | 1999-07-13 | Ferring, B.V. | Stabilized composition for oral administration of peptides |
| SE9604341D0 (sv) * | 1996-11-26 | 1996-11-26 | Ferring Bv | Hepta-peptide oxytocin analogue |
| US7153845B2 (en) * | 1998-08-25 | 2006-12-26 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets |
| US20060025387A1 (en) * | 1998-12-23 | 2006-02-02 | Cytoscan Sciences Llc | Compositions and methods for the treatment of disorders of the central and peripheral nervous systems |
| AR014640A1 (es) * | 1999-02-23 | 2001-03-28 | Univ Nac Quilmes | UNA COMPOSICíoN FARMACÉUTICA INHIBIDORA DE LA DISEMINACIoN METASTÁSICA DURANTE LA CIRUGíA DE UN TUMOR CANCEROSO, UN PROCEDIMENTO DE PREPARACIoN Y UN KIT PARA UNA FORMULACIoN INYECTABLE. |
| US6248363B1 (en) * | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| US7060708B2 (en) * | 1999-03-10 | 2006-06-13 | New River Pharmaceuticals Inc. | Active agent delivery systems and methods for protecting and administering active agents |
| GB2355454A (en) * | 1999-10-20 | 2001-04-25 | Ferring Bv | Antidiuretic agents |
| AT409081B (de) * | 2000-02-16 | 2002-05-27 | Gebro Pharma Gmbh | Stabile, nasal, oral oder sublingual anwendbare pharmazeutische zubereitung |
| GB0015601D0 (en) * | 2000-06-26 | 2000-08-16 | Ferring Bv | Novel antidiuretic agents |
| TWI287984B (en) * | 2000-10-17 | 2007-10-11 | Wyeth Corp | Pharmaceutical composition for modulating bladder function |
| US6509040B1 (en) * | 2001-06-22 | 2003-01-21 | R.P. Scherer Corporation | Fast dispersing dosage forms essentially free of mammalian gelatin |
| US6667277B2 (en) * | 2001-08-24 | 2003-12-23 | National Starch And Chemical Investment Holding Corporation | Water dispersible starch based physical form modification of agricultural agents |
| DE60307082T4 (de) * | 2002-05-07 | 2015-04-30 | Ferring B.V. | In der mundhöhle dispergierbare phamarzeutische zusammensetzung mit desmopressin |
| GB0210397D0 (en) * | 2002-05-07 | 2002-06-12 | Ferring Bv | Pharmaceutical formulations |
| US20060193825A1 (en) * | 2003-04-29 | 2006-08-31 | Praecis Phamaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
| US7094545B2 (en) * | 2003-04-30 | 2006-08-22 | Ferring Bv | Pharmaceutical composition as solid dosage form and method for manufacturing thereof |
| ES2243840T3 (es) * | 2003-07-25 | 2005-12-01 | Ferring B.V. | Composicion farmaceutica de desmopresina como forma farmaceutica solida de dosificacion y metodo para la fabricacion de la misma. |
| CN1826099B (zh) * | 2003-07-25 | 2010-06-09 | 凡林有限公司 | 固体剂型药物组合物及其制造方法 |
| AU2003287591C1 (en) * | 2003-11-10 | 2009-12-10 | Serenity Pharmaceuticals Llc | Pharmaceutical compositions including low dosages of desmopressin |
| PT1530967E (pt) * | 2003-11-13 | 2006-09-29 | Ferring Bv | Embalagem blister e uma forma de dosagem solida que compreende desmopressina. |
| US7344725B2 (en) * | 2003-11-25 | 2008-03-18 | Alcon, Inc. | Use of inorganic nanoparticles to stabilize hydrogen peroxide solutions |
| ES2254858T3 (es) * | 2003-12-29 | 2006-06-16 | Ferring B.V. | Metodo para preparar una forma farmaceutica solida de desmopresina. |
| US7018653B2 (en) * | 2003-12-29 | 2006-03-28 | Ferring B.V. | Method for preparing solid dosage form of desmopressin |
| RU2007139543A (ru) * | 2005-04-22 | 2009-05-27 | Вайет (Us) | Производные бензодиоксана и бензодиоксолана и их применение |
-
2006
- 2006-03-02 SE SE0600482A patent/SE528446C2/sv unknown
- 2006-03-15 SI SI200630038T patent/SI1829532T1/sl unknown
- 2006-03-15 DK DK06005326T patent/DK1829532T3/da active
- 2006-03-15 ES ES06005326T patent/ES2304033T3/es not_active Expired - Lifetime
- 2006-03-15 AT AT06005326T patent/ATE394095T1/de active
- 2006-03-15 EP EP06005326A patent/EP1829532B1/de not_active Revoked
- 2006-03-15 DE DE602006001103T patent/DE602006001103D1/de not_active Expired - Lifetime
- 2006-03-15 PT PT06005326T patent/PT1829532E/pt unknown
- 2006-03-15 PL PL06005326T patent/PL1829532T3/pl unknown
- 2006-03-16 AT AT0020406U patent/AT8372U3/de not_active IP Right Cessation
- 2006-03-16 AT AT0043906A patent/AT503320A1/de not_active Application Discontinuation
- 2006-03-17 NL NL1031397A patent/NL1031397C2/nl not_active IP Right Cessation
- 2006-03-24 DE DE202006004746U patent/DE202006004746U1/de not_active Ceased
-
2007
- 2007-02-28 RU RU2007107368/15A patent/RU2340351C1/ru not_active IP Right Cessation
- 2007-03-01 JP JP2008556715A patent/JP4976428B2/ja not_active Expired - Fee Related
- 2007-03-01 US US12/224,437 patent/US20100273709A1/en not_active Abandoned
-
2008
- 2008-07-31 CY CY20081100802T patent/CY1108231T1/el unknown
- 2008-08-05 IL IL193250A patent/IL193250A0/en unknown
- 2008-08-18 NO NO20083555A patent/NO20083555L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CY1108231T1 (el) | 2014-02-12 |
| SE0600482L (sv) | 2006-11-14 |
| DK1829532T3 (da) | 2008-08-04 |
| ES2304033T3 (es) | 2008-09-01 |
| ATE394095T1 (de) | 2008-05-15 |
| JP4976428B2 (ja) | 2012-07-18 |
| SE528446C2 (sv) | 2006-11-14 |
| SI1829532T1 (sl) | 2008-08-31 |
| IL193250A0 (en) | 2011-08-01 |
| EP1829532B1 (de) | 2008-05-07 |
| NL1031397A1 (nl) | 2006-05-08 |
| JP2009528312A (ja) | 2009-08-06 |
| RU2340351C1 (ru) | 2008-12-10 |
| DE602006001103D1 (de) | 2008-06-19 |
| RU2007107368A (ru) | 2008-09-10 |
| AT8372U3 (de) | 2007-03-15 |
| NO20083555L (no) | 2008-08-18 |
| US20100273709A1 (en) | 2010-10-28 |
| EP1829532A1 (de) | 2007-09-05 |
| AT503320A1 (de) | 2007-09-15 |
| PL1829532T3 (pl) | 2008-09-30 |
| PT1829532E (pt) | 2009-02-13 |
| NL1031397C2 (nl) | 2006-09-18 |
| DE202006004746U1 (de) | 2006-06-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HA9K | Mention of the inventor |
Inventor name: OLSSON LARS-ERIK, MALMOE (SE); NILSSON ANDERS, LUND |
|
| MA9K | Ceased due to renunciation |
Effective date: 20071023 |