AT389117B - Verfahren zur herstellung einer neuen, wasserfreien und stabilen deltakristallform von prazosinhydrochlorid - Google Patents
Verfahren zur herstellung einer neuen, wasserfreien und stabilen deltakristallform von prazosinhydrochloridInfo
- Publication number
- AT389117B AT389117B AT0344184A AT344184A AT389117B AT 389117 B AT389117 B AT 389117B AT 0344184 A AT0344184 A AT 0344184A AT 344184 A AT344184 A AT 344184A AT 389117 B AT389117 B AT 389117B
- Authority
- AT
- Austria
- Prior art keywords
- producing
- free
- new
- water
- crystal form
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI842544A FI79107C (fi) | 1984-06-25 | 1984-06-25 | Foerfarande foer framstaellning av stabil -form av prazosinhydroklorid. |
Publications (2)
Publication Number | Publication Date |
---|---|
ATA344184A ATA344184A (de) | 1989-03-15 |
AT389117B true AT389117B (de) | 1989-10-25 |
Family
ID=8519293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT0344184A AT389117B (de) | 1984-06-25 | 1984-10-30 | Verfahren zur herstellung einer neuen, wasserfreien und stabilen deltakristallform von prazosinhydrochlorid |
Country Status (17)
Country | Link |
---|---|
US (2) | US4739055A (de) |
JP (1) | JPS6115881A (de) |
AT (1) | AT389117B (de) |
AU (1) | AU566814B2 (de) |
BE (1) | BE900925A (de) |
CH (1) | CH661045A5 (de) |
DE (1) | DE3429415A1 (de) |
FI (1) | FI79107C (de) |
FR (1) | FR2567124B1 (de) |
GB (1) | GB2160861B (de) |
IL (1) | IL73267A (de) |
IT (1) | IT1224142B (de) |
LU (1) | LU85616A1 (de) |
NL (1) | NL8403250A (de) |
NZ (1) | NZ209962A (de) |
PT (1) | PT79411B (de) |
ZA (1) | ZA85910B (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3683760D1 (de) * | 1986-03-21 | 1992-03-12 | Heumann Pharma Gmbh & Co | Kristalline, wasserfreie sigma -form von 2-(4-(2-furoyl-(2-piperazin)-1-yl)-4-amino-6,7-dimethoxychinazolinhydrochlorid und verfahren zu ihrer herstellung. |
JP2756846B2 (ja) * | 1989-12-28 | 1998-05-25 | 住化ファインケム株式会社 | 無水のε型結晶体2―〔4―(2―フロイル)ピペラジン―1―イル〕―4―アミノ―6,7―ジメトキシキナゾリン塩酸塩及びその製造方法 |
JPH07206857A (ja) * | 1993-12-28 | 1995-08-08 | Synthelabo Sa | アルフゾシン塩酸塩の二水和物 |
CN100408579C (zh) * | 2001-02-24 | 2008-08-06 | 贝林格尔英格海姆法玛两合公司 | 黄嘌呤衍生物,其制法及其作为药物组合物的用途 |
US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
US7501426B2 (en) * | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
EP1852108A1 (de) * | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | Zusammensetzungen von DPP-IV-Inhibitoren |
NO347644B1 (no) | 2006-05-04 | 2024-02-12 | Boehringer Ingelheim Int | Polymorfer |
PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
WO2009024542A2 (en) * | 2007-08-17 | 2009-02-26 | Boehringer Ingelheim International Gmbh | Purin derivatives for use in the treatment of fab-related diseases |
AR071175A1 (es) | 2008-04-03 | 2010-06-02 | Boehringer Ingelheim Int | Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante |
PE20100156A1 (es) * | 2008-06-03 | 2010-02-23 | Boehringer Ingelheim Int | Tratamiento de nafld |
UY32030A (es) | 2008-08-06 | 2010-03-26 | Boehringer Ingelheim Int | "tratamiento para diabetes en pacientes inapropiados para terapia con metformina" |
KR20200118243A (ko) | 2008-08-06 | 2020-10-14 | 베링거 인겔하임 인터내셔날 게엠베하 | 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료 |
BRPI0917675A2 (pt) * | 2008-08-15 | 2015-12-01 | Boehringer Ingelheim Int | compostos orgânicos para cura de ferida |
MX2011002558A (es) | 2008-09-10 | 2011-04-26 | Boehringer Ingelheim Int | Terapia de combinacion para el tratamiento de diabetes y estados relacionados. |
US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
US8865729B2 (en) | 2008-12-23 | 2014-10-21 | Boehringer Ingelheim International Gmbh | Salt forms of a xanthine compound |
TW201036975A (en) | 2009-01-07 | 2010-10-16 | Boehringer Ingelheim Int | Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy |
AU2010323068B2 (en) | 2009-11-27 | 2015-09-03 | Boehringer Ingelheim International Gmbh | Treatment of genotyped diabetic patients with DPP-IV inhibitors such as linagliptin |
WO2011138421A1 (en) | 2010-05-05 | 2011-11-10 | Boehringer Ingelheim International Gmbh | Combination therapy |
KR20190050871A (ko) | 2010-06-24 | 2019-05-13 | 베링거 인겔하임 인터내셔날 게엠베하 | 당뇨병 요법 |
AR083878A1 (es) | 2010-11-15 | 2013-03-27 | Boehringer Ingelheim Int | Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento |
KR101985384B1 (ko) | 2011-07-15 | 2019-06-03 | 베링거 인겔하임 인터내셔날 게엠베하 | 치환된 퀴나졸린, 이의 제조 및 약제학적 조성물에서의 이의 용도 |
US9555001B2 (en) | 2012-03-07 | 2017-01-31 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition and uses thereof |
EP2849755A1 (de) | 2012-05-14 | 2015-03-25 | Boehringer Ingelheim International GmbH | Xanthinderivat als dpp-4-hemmer zur verwendung bei der behandlung von durch podozyten vermittelten erkrankungen und/oder des nephrotischen syndroms |
WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
WO2015128453A1 (en) | 2014-02-28 | 2015-09-03 | Boehringer Ingelheim International Gmbh | Medical use of a dpp-4 inhibitor |
US10155000B2 (en) | 2016-06-10 | 2018-12-18 | Boehringer Ingelheim International Gmbh | Medical use of pharmaceutical combination or composition |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU980621A3 (ru) * | 1980-02-26 | 1982-12-07 | Орион Ихтюмя Ой (Фирма) | Способ получени @ -формы гидрохлорида працозина |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE156532C (de) * | ||||
US2969375A (en) * | 1961-01-24 | Certification of correction | ||
NL54420C (de) * | 1937-05-25 | |||
GB1156973A (en) * | 1965-07-06 | 1969-07-02 | Quinazoline Derivatives | |
US3433788A (en) * | 1966-04-27 | 1969-03-18 | Union Carbide Corp | Process for recovery of amines from aqueous solutions by solvent treatment and distillation |
US3421983A (en) * | 1967-03-07 | 1969-01-14 | Lummus Co | Azeotropic distillation of aqueous toluene diamine |
US3511836A (en) * | 1967-12-13 | 1970-05-12 | Pfizer & Co C | 2,4,6,7-tetra substituted quinazolines |
US3743672A (en) * | 1970-05-27 | 1973-07-03 | Halcon International Inc | Separation of water in alkylene glycol mono and diester purification by azeotropic distillation |
GB1308718A (en) * | 1970-07-01 | 1973-03-07 | Sir Soc Italiana Resine Spa | Method of separating vinyl acetate from liquid mixtures |
IT956765B (it) * | 1972-06-22 | 1973-10-10 | Montedison Spa | Procedimento per la purificazione di 1 3 diossolano |
US3935213A (en) * | 1973-12-05 | 1976-01-27 | Pfizer Inc. | Process for hypotensive 4-amino-2-(piperazin-1-yl) quinazoline derivatives |
US4026894A (en) * | 1975-10-14 | 1977-05-31 | Abbott Laboratories | Antihypertensive agents |
US4001237A (en) * | 1976-02-18 | 1977-01-04 | Bristol-Myers Company | Oxazole, isoxazole, thiazole and isothiazole amides |
US4092315A (en) * | 1976-03-01 | 1978-05-30 | Pfizer Inc. | Novel crystalline forms of prazosin hydrochloride |
FI67699C (fi) * | 1979-01-31 | 1985-05-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan |
-
1984
- 1984-06-25 FI FI842544A patent/FI79107C/fi not_active IP Right Cessation
- 1984-08-09 DE DE19843429415 patent/DE3429415A1/de active Granted
- 1984-10-03 GB GB08424999A patent/GB2160861B/en not_active Expired
- 1984-10-15 US US06/660,871 patent/US4739055A/en not_active Expired - Lifetime
- 1984-10-19 AU AU34510/84A patent/AU566814B2/en not_active Ceased
- 1984-10-19 IL IL73267A patent/IL73267A/xx not_active IP Right Cessation
- 1984-10-23 NZ NZ209962A patent/NZ209962A/en unknown
- 1984-10-24 IT IT23292/84A patent/IT1224142B/it active
- 1984-10-25 NL NL8403250A patent/NL8403250A/nl not_active Application Discontinuation
- 1984-10-26 PT PT79411A patent/PT79411B/pt not_active IP Right Cessation
- 1984-10-26 CH CH5142/84A patent/CH661045A5/de not_active IP Right Cessation
- 1984-10-26 FR FR8416401A patent/FR2567124B1/fr not_active Expired - Fee Related
- 1984-10-29 BE BE0/213911A patent/BE900925A/fr not_active IP Right Cessation
- 1984-10-29 JP JP59227640A patent/JPS6115881A/ja active Granted
- 1984-10-29 LU LU85616A patent/LU85616A1/fr unknown
- 1984-10-30 AT AT0344184A patent/AT389117B/de not_active IP Right Cessation
-
1985
- 1985-02-06 ZA ZA85910A patent/ZA85910B/xx unknown
-
1988
- 1988-02-08 US US07/153,780 patent/US4873330A/en not_active Expired - Fee Related
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU980621A3 (ru) * | 1980-02-26 | 1982-12-07 | Орион Ихтюмя Ой (Фирма) | Способ получени @ -формы гидрохлорида працозина |
Also Published As
Publication number | Publication date |
---|---|
IL73267A0 (en) | 1985-01-31 |
ZA85910B (en) | 1985-09-25 |
US4873330A (en) | 1989-10-10 |
IL73267A (en) | 1988-06-30 |
DE3429415C2 (de) | 1990-05-03 |
DE3429415A1 (de) | 1986-01-02 |
FI842544A0 (fi) | 1984-06-25 |
NL8403250A (nl) | 1986-01-16 |
AU566814B2 (en) | 1987-10-29 |
FI79107C (fi) | 1989-11-10 |
US4739055A (en) | 1988-04-19 |
FI79107B (fi) | 1989-07-31 |
GB2160861B (en) | 1987-11-18 |
IT8423292A0 (it) | 1984-10-24 |
JPS6115881A (ja) | 1986-01-23 |
IT1224142B (it) | 1990-09-26 |
FI842544A (fi) | 1985-12-26 |
ATA344184A (de) | 1989-03-15 |
JPH0481993B2 (de) | 1992-12-25 |
FR2567124B1 (fr) | 1990-09-21 |
PT79411A (en) | 1984-11-01 |
CH661045A5 (de) | 1987-06-30 |
AU3451084A (en) | 1986-01-02 |
LU85616A1 (fr) | 1985-06-04 |
GB8424999D0 (en) | 1984-11-07 |
PT79411B (en) | 1986-09-15 |
FR2567124A1 (fr) | 1986-01-10 |
GB2160861A (en) | 1986-01-02 |
NZ209962A (en) | 1987-06-30 |
BE900925A (fr) | 1985-02-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AT389117B (de) | Verfahren zur herstellung einer neuen, wasserfreien und stabilen deltakristallform von prazosinhydrochlorid | |
ATA20485A (de) | Verfahren zur herstellung von neuen tetrahydrocarbazol-derivaten | |
ATA245485A (de) | Verfahren zur herstellung von neuen dihydropyridincarbonsaeure-derivaten | |
ATA28687A (de) | Verfahren zur herstellung von neuen dichloranilinderivaten | |
ATA267888A (de) | Verfahren zur herstellung von neuen 1,4-dihydro-4-oxonaphthydridin-derivaten und deren salzen | |
PT83186A (de) | Verfahren zur herstellung einer stabilen modifikation von torasemid sowie arzneimittel enthaltend torasemid | |
ATA193185A (de) | Verfahren zur herstellung von neuen substituierten benzamiden | |
AT385755B (de) | Verfahren zur herstellung von neuen pyrensulfonsaeurederivaten | |
ATA251585A (de) | Verfahren zur herstellung von neuen ethylendiaminmonoamid-derivaten | |
AT372390B (de) | Verfahren zur herstellung von neuen 4'-jodderivaten von anthracyclinglykosiden | |
ATA5985A (de) | Verfahren zur herstellung von neuen 8alpha-acylaminoergolinen | |
ATA101986A (de) | Verfahren zur herstellung von neuen 5-pyrimidincarboxamiden und deren additionssalzen | |
AT386197B (de) | Verfahren zur herstellung von neuen indolderivaten | |
ATA273486A (de) | Verfahren zur herstellung von neuen dichloranilinderivaten | |
ATA149286A (de) | Verfahren zur herstellung von neuen chinolinderivaten | |
AT384218B (de) | Verfahren zur herstellung von neuen chinazolin-derivaten | |
ATA313686A (de) | Verfahren zur herstellung von neuen carbapenemderivaten | |
ATA298586A (de) | Verfahren zur herstellung von neuen anthracyclinglykosiden | |
ATA284985A (de) | Verfahren zur herstellung von neuen carbapenemderivaten | |
AT386407B (de) | Verfahren zur herstellung von neuen n-sulfamyl -3-halogenpropionamidinen | |
ATA52285A (de) | Verfahren zur herstellung von neuen diazepinoindolen | |
ATA326986A (de) | Verfahren zur herstellung von neuen optisch aktiven 2-chlor-12-/3-dimethylamino-2-methylpropyl/-12h-dibenzo/d,g//1,3,6/dioxazocinen und saeureadditionssalzen derselben | |
PT82393A (de) | Verfahren zur herstellung von neuen benzoesaeurederivaten | |
ATA223986A (de) | Verfahren zur herstellung von neuen dihydropyridinderivaten | |
AT389307B (de) | Verfahren zur herstellung von neuen apovincaminolderivaten und ihren saeureadditionssalzen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELJ | Ceased due to non-payment of the annual fee | ||
ELJ | Ceased due to non-payment of the annual fee |